BACKGROUND Situs inversus totalis(SIT)is a rare congenital anomaly characterized by complete mirror-image transposition of thoracic and abdominal organs.The presence of gallstone disease in these patients represents a...BACKGROUND Situs inversus totalis(SIT)is a rare congenital anomaly characterized by complete mirror-image transposition of thoracic and abdominal organs.The presence of gallstone disease in these patients represents a diagnostic and technical challenge,particularly when laparoscopic cholecystectomy is indicated.CASE SUMMARY We report two cases of symptomatic gallstone disease in patients with SIT.The first case involved a 27-year-old female diagnosed with cholelithiasis following radiological evaluation,while the second case involved a 45-year-old male presenting with cholelithiasis and choledocholithiasis requiring preoperative endoscopic retrograde cholangiopancreatography.Cases were identified retrospectively from institutional surgical records.Data were collected from clinical charts,imaging studies,operative reports,and follow-up visits.In both patients,laparoscopic cholecystectomy was successfully performed using a mirror-image port placement strategy.No intraoperative or postoperative complications occurred,and both patients were discharged on the first postoperative day.CONCLUSION Laparoscopic cholecystectomy in patients with SIT is safe and feasible when meticulous preoperative imaging and careful adaptation of surgical technique are employed.Awareness of mirror-image anatomy and strict adherence to the critical view of safety are essential to minimize the risk of iatrogenic injury.展开更多
摘要BACKGROUND Situs inversus totalis(SIT)is a rare congenital anomaly characterized by complete mirror-image transposition of thoracic and abdominal organs.The presence of gallstone disease in these patients represents a diagnostic and technical challenge,particularly when laparoscopic cholecystectomy is indicated.CASE SUMMARY We report two cases of symptomatic gallstone disease in patients with SIT.The first case involved a 27-year-old female diagnosed with cholelithiasis following radiological evaluation,while the second case involved a 45-year-old male presenting with cholelithiasis and choledocholithiasis requiring preoperative endoscopic retrograde cholangiopancreatography.Cases were identified retrospectively from institutional surgical records.Data were collected from clinical charts,imaging studies,operative reports,and follow-up visits.In both patients,laparoscopic cholecystectomy was successfully performed using a mirror-image port placement strategy.No intraoperative or postoperative complications occurred,and both patients were discharged on the first postoperative day.CONCLUSION Laparoscopic cholecystectomy in patients with SIT is safe and feasible when meticulous preoperative imaging and careful adaptation of surgical technique are employed.Awareness of mirror-image anatomy and strict adherence to the critical view of safety are essential to minimize the risk of iatrogenic injury.