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Psychological intervention and health education effects on quality of life in patients after pancreatic cancer surgery:A meta-analysis 认领 引用
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作者 Xiao-Lan Shi Jia-Ping Chen +3 位作者 He Li Bi-Rong Zhao Dong-Mei Xu Lu-Qing Xu 《World Journal of Gastrointestinal Surgery》 SCIE 2026年第5期352-366,共15页
BACKGROUND Pancreatic cancer is one of the most aggressive malignancies,and surgery remains the only potentially curative treatment.However,postoperative complications,psychological distress,and treatment-related symp... BACKGROUND Pancreatic cancer is one of the most aggressive malignancies,and surgery remains the only potentially curative treatment.However,postoperative complications,psychological distress,and treatment-related symptoms can severely impair quality of life(QoL)of patients.Although psychological interventions and health education have shown beneficial effects in other cancer populations,their effectiveness in postoperative patients with pancreatic cancer remains inconsistent and inadequately synthesized.We hypothesized that structured psychological and educational support would improve global health status,functional outcomes,and the symptom burden of postoperative patients with pancreatic cancer compared to standard care.AIM To determine how psychological intervention and health education affects the QoL of postoperative patients with pancreatic cancer.METHODS We searched PubMed,EMBASE,Cochrane Library,Web of Science,CINAHL,and MEDLINE from inception to October 2025.Two investigators independently screened studies,extracted data,and assessed bias.Quality was appraised using the Cochrane Risk of Bias tool(RoB 2.0),and the primary effect measure was the standardized mean difference(SMD)derived from a meta-analysis using RevMan 5.4.RESULTS Of the 1613 records initially identified,six studies involving 712 patients were included in the final analysis after applying exclusion criteria.The meta-analysis revealed that,compared with usual care,psychological interventions and health education significantly improved patients’global health status[MD=7.12,95%confidence interval(CI):4.91 to 9.32,P<0.001],physical functioning(SMD=0.61,95%CI:0.37 to 0.85,P<0.001),role functioning(SMD=0.64,95%CI:0.33 to 0.94,P<0.001),emotional functioning(SMD=1.03,95%CI:0.78 to 1.28,P<0.001),dietary digestion(MD=-2.37,95%CI:-3.12 to-1.63,P<0.001),and nursing satisfaction(MD=0.69,95%CI:0.50 to 0.88,P<0.001).CONCLUSION Psychological interventions combined with health education can improve global health status,alleviate symptom burden,and enhance functional outcomes compared to standard care among postoperative patients with pancreatic cancer. 展开更多
关键词 Psychological intervention Health education Pancreatic cancer Quality of life Systematic review Meta-analysis
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