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Pile installation effects in natural soft clays:A semi-analytical solution using strain path method 认领 引用
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作者 Liang Li Pan Zhou +3 位作者 Jingpei Li Seyedmohsen Miraei Peng Feng Mingdong Wei 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2026年第1期728-744,共17页
This paper develops a semi-analytical solution for pile penetration in natural soft clays using the strain path method(SPM).The stress-strain behavior of soils is characterized by the S-CLAY1S model,which can capture ... This paper develops a semi-analytical solution for pile penetration in natural soft clays using the strain path method(SPM).The stress-strain behavior of soils is characterized by the S-CLAY1S model,which can capture the anisotropic evolution and destructuring nature of soft clays.By integrating the S-CLAY1S model into the theoretical framework of the SPM,a set of ordinary differential equations is formulated with respect to the vertical coordinate of soil particles.The distribution of excess pore water pressure(EPWP)following pile installation is approximated through one-dimensional(1D)radial integration around the pile shaft.The distribution of stresses and EPWP,along with the evolution of fabric anisotropy within the soil surrounding the pile,is presented to illustrate the response of pile penetration in natural soft clays.The proposed solution is validated against existing theoretical solutions using the SPM and cavity expansion method(CEM),along with experimental data.The findings demonstrate that the SPM reveals lower radial effective stresses and EPWP at the pile shaft than that of CEM.Pile penetration alters the soil's anisotropic properties,inducing rotational hardening and affecting post-installation stress distribution.Soil destructuration eliminates bonding among particles near the pile,resulting in a complete disruption of soil structure at the pile surface,which is particularly pronounced for higher initial soil structure ratios.Minimal variation was observed in the three principal stresses and shear stress on the cone side surface as the angle increased from 18°to 60°,except for a slight reduction in EPWP. 展开更多
关键词 Pile penetration Strain path method Natural soft clays Anisotropy evolution Destructuration
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Multi-omic analysis for dietary supplementation of different ratios of soluble and insoluble fiber on intestinal microbiota,metabolites and inflammation of weaned piglets 认领 引用
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作者 Yetong Xu Chengyu Zhou +7 位作者 Yingying Lu Xutong Guo Minyue Zong Junwei Zhu Pan Zhou Jiaman Pang Xie Peng Zhihong Sun 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2026年第4期1606-1618,共13页
Different types of dietary fiber(DF)play important roles in enhancing intestinal health and overall performance in animals.This study investigated the effects of high-DF diets containing different ratios of soluble to... Different types of dietary fiber(DF)play important roles in enhancing intestinal health and overall performance in animals.This study investigated the effects of high-DF diets containing different ratios of soluble to insoluble dietary fiber(SDF:IDF)on growth performance,intestinal barrier integrity,microbiota,and metabolite profiles in weaned piglets.The four dietary treatments consisted of a basal diet(CON)and three high-DF diets with SDF:IDF ratios of 0.37,0.25,and 0.13(designated HF-0.37,HF-0.25,and HF-0.13,respectively).On days 14 and 28,colonic tumor necrosis factor-α,interleukin-1β,interleukin-6,and interleukin-8 concentrations were higher in the HF-0.37 group than in the CON,HF-0.25,and HF-0.13 groups(P<0.05).Plasma D-lactate and endotoxin levels were lower in the HF-0.25 group compared to the CON group at both time points(P<0.05).Furthermore,colonic zonula occludens 1 expression was upregulated in the HF-0.25 and HF-0.13 groups compared to the CON and HF-0.37 groups on day 14(P<0.05).At the transcriptional level,all three high-DF diets modulated signaling pathways associated with inflammation and immune responses in the colon.Notably,DF supplementation particularly the HF-0.25 diet upregulated colonic levels of 3-indole butyric acid,nicotinic acid,and 3-methylthiopropylamine on d 14 and reduced certain peptide levels by d 28.These findings indicate that DF supplementation,especially at an SDF:IDF ratio of 0.25,exerts beneficial effects on intestinal integrity in weaned piglets,potentially mediated by alterations in colonic metabolite profiles,whereas HF-0.37 and HF-0.13 exhibited limited impacts on intestinal barrier function. 展开更多
关键词 weaned piglets soluble fiber insoluble fiber multi-omics intestinal integrity
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Advances in organoelectrochemical copper-catalyzed reactions 认领 引用
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作者 Pan Zhou Ting Zou +2 位作者 Hong-Jian Song Yu-Xiu Liu Qing-Min Wang 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第1期25-38,共14页
The combination of electrochemistry and metal catalysts has been a popular research topic in the field of organic synthesis due to the abundance and controllable valence states of transition metals,where electron tran... The combination of electrochemistry and metal catalysts has been a popular research topic in the field of organic synthesis due to the abundance and controllable valence states of transition metals,where electron transfer at the electrode produces catalysts with more valence states.Among these transition metal catalysts,electrochemical conversions catalyzed by inexpensive copper metals have received considerable attention.This article systematically investigated this field and reviewed the electrochemical copper catalytic methods applied in organic synthesis from the different activation modes of substrates,which can be broadly classified into the functionalization of C=C bonds,C-H bond activation,C-C and C-X bond activation,and so on. 展开更多
关键词 Electrochemistry Transition metal catalysis Copper catalysis Copper electrocatalysis
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Thermophysical-mechanical behaviors of hot dry granite subjected to thermal shock cycles and dynamic loadings 认领 引用 被引量：2
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作者 Ju Wang Feng Dai +2 位作者 Yi Liu Hao Tan Pan Zhou 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2025年第9期5437-5452,共16页
Exploring dynamic mechanical responses and failure behaviors of hot dry rock(HDR)is significant for geothermal exploitation and stability assessment.In this study,via the split Hopkinson pressure bar(SHPB)system,a ser... Exploring dynamic mechanical responses and failure behaviors of hot dry rock(HDR)is significant for geothermal exploitation and stability assessment.In this study,via the split Hopkinson pressure bar(SHPB)system,a series of dynamic compression tests were conducted on granite treated by cyclic thermal shocks at different temperatures.We analyzed the effects of cyclic thermal shock on the thermal-related physical and dynamic mechanical behaviors of granite.Specifically,the P-wave velocity,dynamic strength,and elastic modulus of the tested granite decrease with increasing temperature and cycle number,while porosity and peak strain increase.The degradation law of dynamic mechanical properties could be described by a cubic polynomial.Cyclic thermal shock promotes shear cracks propagation,causing dynamic failure mode of granite to transition from splitting to tensile-shear composite failure,accompanied by surface spalling and debris splashing.Moreover,the thermal shock damage evolution and coupled failure mechanism of tested granite are discussed.The evolution of thermal shock damage with thermal shock cycle numbers shows an obvious S-shaped surface,featured by an exponential correlation with dynamic mechanical parameters.In addition,with increasing thermal shock temperature and cycles,granite mineral species barely change,but the length and width of thermal cracks increase significantly.The non-uniform expansion of minerals,thermal shock-induced cracking,and water-rock interaction are primary factors for deteriorating dynamic mechanical properties of granite under cyclic thermal shock. 展开更多
关键词 Geothermal exploitation Cyclic thermal shock Granite Thermal-related physical properties Dynamic mechanical behavior Failure mechanism
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Leveraging Bayesian methods for addressing multi-uncertainty in data-driven seismic liquefaction assessment 认领 引用
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作者 Zhihui Wang Roberto Cudmani +2 位作者 Andrés Alfonso Peña Olarte Chaozhe Zhang Pan Zhou 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2025年第4期2474-2491,共18页
When assessing seismic liquefaction potential with data-driven models,addressing the uncertainties of establishing models,interpreting cone penetration tests(CPT)data and decision threshold is crucial for avoiding bia... When assessing seismic liquefaction potential with data-driven models,addressing the uncertainties of establishing models,interpreting cone penetration tests(CPT)data and decision threshold is crucial for avoiding biased data selection,ameliorating overconfident models,and being flexible to varying practical objectives,especially when the training and testing data are not identically distributed.A workflow characterized by leveraging Bayesian methodology was proposed to address these issues.Employing a Multi-Layer Perceptron(MLP)as the foundational model,this approach was benchmarked against empirical methods and advanced algorithms for its efficacy in simplicity,accuracy,and resistance to overfitting.The analysis revealed that,while MLP models optimized via maximum a posteriori algorithm suffices for straightforward scenarios,Bayesian neural networks showed great potential for preventing overfitting.Additionally,integrating decision thresholds through various evaluative principles offers insights for challenging decisions.Two case studies demonstrate the framework's capacity for nuanced interpretation of in situ data,employing a model committee for a detailed evaluation of liquefaction potential via Monte Carlo simulations and basic statistics.Overall,the proposed step-by-step workflow for analyzing seismic liquefaction incorporates multifold testing and real-world data validation,showing improved robustness against overfitting and greater versatility in addressing practical challenges.This research contributes to the seismic liquefaction assessment field by providing a structured,adaptable methodology for accurate and reliable analysis. 展开更多
关键词 Data-driven method Bayes analysis Seismic liquefaction Uncertainty Neural network
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N-acylethanolamine acid amidase inhibitor-loaded polymeric micelles in the treatment of dry eye disease 认领 引用
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作者 Yang Zhao Pan Zhou +6 位作者 Bang-Yan Zhou Wen-Xuan Zeng Qi-Yue Du Fang-Yu Chen Jie Ren Hong-Wei Fu Yan Qiu 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2025年第10期1815-1822,共8页
AIM:To investigate F96,a N-acylethanolamine acid amidase(NAAA)inhibitor,as a novel drug for treating dry eye disease(DED)and to enhance its corneal retention time by utilizing nanometer micelles to improve therapeutic... AIM:To investigate F96,a N-acylethanolamine acid amidase(NAAA)inhibitor,as a novel drug for treating dry eye disease(DED)and to enhance its corneal retention time by utilizing nanometer micelles to improve therapeutic efficacy.METHODS:The study compared nanomicelles encapsulating doxorubicin with an aqueous solution of doxorubicin to assess the ability of the nanomicelles to prolong drug retention on the ocular surface.Dry eye was induced in mice through subcutaneous injections of scopolamine hydrobromide.The efficacy of F96 was evaluated using various clinical assessments,including the phenol red cotton test,Oregon green dextran staining,periodic acid-Schiff(PAS)staining,and Terminal dUTP Nick-End Labeling(TUNEL)assay.RESULTS:Doxorubicin micelles exhibited significantly prolonged retention compared to the aqueous solution.By 15min,the corneal fluorescence intensity of the micelle group was markedly higher than that of theaqueous solution group(P<0.05),and this enhanced effect persisted for at least 4h.Furthermore,mice treated with F96 demonstrated superior outcomes in tear production,corneal staining,and goblet cell density compared to the control groups.Specifically,F96-mPPP significantly increased tear secretion(3.35±0.45 vs 1.85±0.51 mm in the vehicle group,P<0.001),restored conjunctival goblet cell density(54.5±4.5 vs 31.3±3.0,P<0.01),and reduced corneal fluorescein staining scores(3.4±0.32 vs 6.5±0.72,P<0.001).Additionally,F96-mPPP treatment markedly decreased TUNEL-positive cells in the corneal epithelium,indicating suppression of apoptosis.CONCLUSION:F96 nanometer micelles have the potential to serve as a promising novel approach for effectively alleviating ocular surface damage in the treatment of dry eye disease. 展开更多
关键词 dry eye disease F96 retention time micelles
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迷宫与无限——华黎静艺术作品对谈录 认领 引用
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作者 华黎静 潘周 王晓琼 《苏州工艺美术职业技术学院学报》 2026年第1期98-100,共3页
在全球化语境下,中国当代艺术家正面临一个永恒的命题:如何在继承传统的基础上,重塑语言结构,并建立起属于自己的视觉系统。出生于苏州、毕业于南京艺术学院的华黎静,长期致力于传统文化的当代表达与视觉语言的实验性建构。他的系列作品... 在全球化语境下,中国当代艺术家正面临一个永恒的命题:如何在继承传统的基础上,重塑语言结构,并建立起属于自己的视觉系统。出生于苏州、毕业于南京艺术学院的华黎静,长期致力于传统文化的当代表达与视觉语言的实验性建构。他的系列作品,以严谨的构图与富有张力的图像系统,构筑出一个跨越传统与当代、物质与虚拟、理性与神秘的视觉张力场,体现出他对文化母体的深层次再认知与重构能力。本文通过艺术家、策展人和传媒人的对谈,从创作观念、形式语言与文化阐释三个维度展开分析,梳理其图像生成机制与视觉修辞路径,探讨其如何在传统资源的当代转译中实现符号更新与意义再生产。 展开更多
关键词 当代艺术 油画 视觉语言
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A review of fire-extinguishing agent on suppressing lithium-ion batteries fire 认领 引用 被引量：33
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作者 Shuai Yuan Chongye Chang +4 位作者 Shuaishuai Yan Pan Zhou Xinming Qian Mengqi Yuan Kai Liu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2021年第11期262-280,I0006,共19页
Safety issue of lithium-ion batteries(LIBs)such as fires and explosions is a significant challenge for their large scale applications.Considering the continuously increased battery energy density and wider large-scale... Safety issue of lithium-ion batteries(LIBs)such as fires and explosions is a significant challenge for their large scale applications.Considering the continuously increased battery energy density and wider large-scale battery pack applications,the possibility of LIBs fire significantly increases.Because of the fast burning and the easy re-ignition characteristics of LIBs,achieving an efficient and prompt LIBs fire suppression is critical for minimizing the fire hazards.Different from conventional fire hazards,the LIBs fire shows complicated and comprehensive characteristics,and an effective and suitable fire-extinguishing agent particularly designed for LIBs is highly desirable.Considerable efforts have been devoted to this topic,to the best of our knowledge,a comprehensive review on this regard is still rare.Moreover,in practice,a guidance for the design and selections of a proper fire-extinguishing agent for LIBs is urgently needed.Herein,the special mechanisms and characteristics for LIBs fire and the corresponding design principles for LIBs fire-extinguishing agent were introduced.It is revealed that a fire-extinguishing agent developed for LIBs fire will most likely need a high heat capacity,high wetting,low viscosity and low electrical conductivity.After a comprehensive comparison of these agents in terms of these performances,water-based fire-extinguishing agents show best.Several typical fire-extinguishing agents such as gaseous agents,dry powders,water-based and aerosol fire-extinguishing agents were then introduced,and their fire extinguishment mechanisms were presented.Finally,their effectiveness in suppressing the fire were summarized.Water-based fire-extinguishing agents possess high cooling capacity and excellent anti-reflash performance for the fire.We believe this review could shed light on developing an efficient fire-extinguishing agent particularly designed for LIBs. 展开更多
关键词 Lithium-ion battery Battery safety Fire-extinguishing agent Fire suppression
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Regulating the growth of lithium dendrite by coating an ultra-thin layer of gold on separator for improving the fast-charging ability of graphite anode 认领 引用 被引量：6
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作者 Shuaishuai Yan Xiaoxia Chen +5 位作者 Pan Zhou Peican Wang Hangyu Zhou Weili Zhang Yingchun Xia Kai Liu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2022年第4期467-473,共7页
With the ever-growing application of lithium-ion batteries(LIBs), their fast-charging technology has attracted great interests of scientists. However, growth of lithium dendrites during fast charge of the bat teries w... With the ever-growing application of lithium-ion batteries(LIBs), their fast-charging technology has attracted great interests of scientists. However, growth of lithium dendrites during fast charge of the bat teries with high energy density may pose great threats to the operation and cause serious safety issues Herein, we prepared a functional separator with an ultra-thin(20 nm) layer of Au nanoparticles deposited by evaporation coating method which could regulate growth direction and morphology of the lithium dendrites, owing to nearly zero overpotential of lithium meal nucleation on lithiated Au. Once the Li den drites are about to form on the graphite anode during fast charging(or lithiation), they plate predomi nantly on the Au deposited separator rather than on the graphite. Such selective deposition does no compromise the electrochemical performance of batteries under normal cycling. More importantly, i enables the better cycling stability of batteries at fast charge condition. The Li/Graphite cells with Au nanoparticles coated separator could cycle stably with a high areal capacity retention of 90.5% over 95 cycles at the current density of 0.72 m A cm-2. The functional separator provides an effective strategy to adjust lithium plating position at fast charge to ensure high safety of batteries without a compromise on the energy density of LIBs. 展开更多
关键词 Fast-charging Functional separator Lithium-ion batteries Dendrites Safety
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Recent Advances in Electrolytes for High-Voltage Cathodes of Lithium-Ion Batteries 认领 引用 被引量：8
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作者 Wenhui Hou Yang Lu +5 位作者 Yu Ou Pan Zhou Shuaishuai Yan Xi He Xuewen Geng Kai Liu 《Transactions of Tianjin University》 EI CAS 2023年第2期120-135,共16页
With the increasing scale of energy storage,it is urgently demanding for further advancements on battery technologies in terms of energy density,cost,cycle life and safety.The development of lithium-ion batteries(LIBs... With the increasing scale of energy storage,it is urgently demanding for further advancements on battery technologies in terms of energy density,cost,cycle life and safety.The development of lithium-ion batteries(LIBs)not only relies on electrodes,but also the functional electrolyte systems to achieve controllable formation of solid electrolyte interphase and high ionic conductivity.In order to satisfy the needs of higher energy density,high-voltage(>4.3 V)cathodes such as Li-rich layered compounds,olivine LiNiPO4,spinel LiNi0.5Mn1.5O4 have been extensively studied.However,high-voltage cathodebased LIBs fade rapidly mainly owing to the anodic decomposition of electrolytes,gradually thickening of interfacial passivation layer and vast irreversible capacity loss,hence encountering huge obstacle toward practical applications.To tackle this roadblock,substantial progress has been made toward oxidation-resistant electrolytes to block its side reaction with high-voltage cathodes.In this review,we discuss degradation mechanisms of electrolytes at electrolyte/cathode interface and ideal requirements of electrolytes for high-voltage cathode,as well as summarize recent advances of oxidation-resistant electrolyte optimization mainly from solvents and additives.With these insights,it is anticipated that development of liquid electrolyte tolerable to high-voltage cathode will boost the large-scale practical applications of high-voltage cathode-based LIBs. 展开更多
关键词 High-voltage cathodes Oxidation resistance Electrolytes optimization Solvents Additives
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Association of cardiometabolic multimorbidity with all-cause and cardiovascular disease mortality among Chinese hypertensive patients 认领 引用 被引量：10
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作者 Luo-Xi XIAO Zi-Yu WANG +12 位作者 Jiang-Tao LI Hai-Mei WANG Yi-Ming HAO Pan ZHOU Yu-Lin HUANG Qiu-Ju DENG Yong-Chen HAO Na YANG Li-Zhen HAN Zhao YANG Ping-Ping JIA Yue QI Jing LIU 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2024年第2期211-218,共8页
BACKGROUND Hypertension usually clusters with multiple comorbidities.However,the association between cardiometabolic multimorbidity(CMM)and mortality in hypertensive patients is unclear.This study aimed to investigate... BACKGROUND Hypertension usually clusters with multiple comorbidities.However,the association between cardiometabolic multimorbidity(CMM)and mortality in hypertensive patients is unclear.This study aimed to investigate the association between CMM and all-cause and cardiovascular disease(CVD)mortality in Chinese patients with hypertension.METHODS The data used in this study were from the China National Survey for Determinants of Detection and Treatment Status of Hypertensive Patients with Multiple Risk Factors(CONSIDER),which comprised 5006 participants aged 19–91 years.CMM was defined as the presence of one or more of the following morbidities:diabetes mellitus,dyslipidemia,chronic kidney disease,coronary heart disease,and stroke.Cox proportional hazard models were used to calculate the hazard ratios(HR)with 95%CI to determine the association between the number of CMMs and both all-cause and CVD mortality.RESULTS Among 5006 participants[mean age:58.6±10.4 years,50%women(2509 participants)],76.4%of participants had at least one comorbidity.The mortality rate was 4.57,4.76,8.48,and 16.04 deaths per 1000 person-years in hypertensive patients without any comorbidity and with one,two,and three or more morbidities,respectively.In the fully adjusted model,hypertensive participants with two cardiometabolic diseases(HR=1.52,95%CI:1.09–2.13)and those with three or more cardiometabolic diseases(HR=2.44,95%CI:1.71–3.48)had a significantly elevated risk of all-cause mortality.The findings were similar for CVD mortality but with a greater increase in risk magnitude.CONCLUSIONS In this study,three-fourths of hypertensive patients had CMM.Clustering with two or more comorbidities was associated with a significant increase in the risk of all-cause and cardiovascular mortality among hypertensive patients,suggesting more intensive treatment and control in this high-risk patient group. 展开更多
关键词 hypertensive patients morbidity
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Smart materials for safe lithium-ion batteries against thermal runaway 认领 引用 被引量：4
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作者 Yu Ou Pan Zhou +5 位作者 Wenhui Hou Xiao Ma Xuan Song Shuaishuai Yan Yang Lu Kai Liu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第7期360-392,共33页
In recent years,the new energy storage system,such as lithium ion batteries(LIBs),has attracted much attention.In order to meet the demand of industrial progress for longer cycle life,higher energy density and cost ef... In recent years,the new energy storage system,such as lithium ion batteries(LIBs),has attracted much attention.In order to meet the demand of industrial progress for longer cycle life,higher energy density and cost efficiency,a quantity of research has been conducted on the commercial application of LIBs.However,it is difficult to achieve satisfying safety and cycling performance simultaneously.There may be thermal runaway(TR),external impact,overcharge and overdischarge in the process of battery abuse,which makes the safety problem of LIBs more prominent.In this review,we summarize recent progress in the smart safety materials design towards the goal of preventing TR of LIBs reversibly from different abuse conditions.Benefiting from smart responsive materials and novel structural design,the safety of LIBs can be improved a lot.We expect to provide a comprehensive reference for the development of smart and safe lithium-based battery materials. 展开更多
关键词 Lithium ion batteries(LIBs) Thermal runaway(TR) Smart materials Safe batteries Solid electrolyte interface(SEI)
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Theoretical investigation on axial cyclic performance of monopile in sands using interface constitutive models 认领 引用 被引量：2
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作者 Pan Zhou Jingpei Li +2 位作者 Kaoshan Dai Stefan Vogt Seyedmohsen Miraei 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第7期2645-2662,共18页
Cyclic loads generated by environmental factors,such as winds,waves,and trains,will likely lead to performance degradation in pile foundations,resulting in issues like permanent displacement accumulation and bearing c... Cyclic loads generated by environmental factors,such as winds,waves,and trains,will likely lead to performance degradation in pile foundations,resulting in issues like permanent displacement accumulation and bearing capacity attenuation.This paper presents a semi-analytical solution for predicting the axial cyclic behavior of piles in sands.The solution relies on two enhanced nonlinear load-transfer models considering stress-strain hysteresis and cyclic degradation in the pile-soil interaction.Model parameters are calibrated through cyclic shear tests of the sand-steel interface and laboratory geotechnical testing of sands.A novel aspect involves the meticulous formulation of the shaft loadtransfer function using an interface constitutive model,which inherently inherits the interface model’s advantages,such as capturing hysteresis,hardening,degradation,and particle breakage.The semi-analytical solution is computed numerically using the matrix displacement method,and the calculated values are validated through model tests performed on non-displacement and displacement piles in sands.The results demonstrate that the predicted values show excellent agreement with the measured values for both the static and cyclic responses of piles in sands.The displacement pile response,including factors such as bearing capacity,mobilized shaft resistance,and convergence rate of permanent settlement,exhibit improvements compared to non-displacement piles attributed to the soil squeezing effect.This methodology presents an innovative analytical framework,allowing for integrating cyclic interface models into the theoretical investigation of pile responses. 展开更多
关键词 Piles Cyclic degradation Load-transfer models Interface constitutive model Semi-analytical solution Model tests
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An Untethered Soft-Swallowing Robot with Enhanced Heat Resistance,Damage Tolerance,and Impact Mitigation 认领 引用
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作者 Haili Li Xingzhi Li +1 位作者 Pan Zhou Jiantao Yao 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第6期456-465,共10页
Soft robotics focuses on addressing the locomotion problem in unstructured environments and the manipulation problem of non-cooperative objects,which inevitably leads to soft robots encountering multiple uncertainties... Soft robotics focuses on addressing the locomotion problem in unstructured environments and the manipulation problem of non-cooperative objects,which inevitably leads to soft robots encountering multiple uncertainties and damages.Therefore,improving the robustness of soft robots in hostile environmental conditions has always been a challenge.Existing methods usually improve this robustness through damage isolation,material elasticity,and self-healing mechanisms.In contrast to existing methods,this paper proposes a method to improve the robustness of an untethered soft-swallowing robot based on the physical properties of fluids,such as the high specific heat capacity of water,the viscosity of soft glue,and the shear thickening of non-Newtonian fluids.Based on this method,we developed a soft-swallowing robot with enhanced heat resistance,damage tolerance,and impact mitigation capability by only replacing its fluid working medium.Experiments show that the developed soft-swallowing robot can withstand high temperatures above 600°C,maintain high performance even after enduring hundreds of damages,and protect grasped object from more than 90%of external impacts.This principle extends beyond the three fluids used in this study.Other fluids,such as magnetic fluid,can increase adhesion to metal materials,whereas oily fluids can reduce frictional resistance between soft structures.Additionally,other solid materials with elasticity and compliance can serve as alternative working mediums for the soft-swallowing robot.This work contributes an effective method for fluid-dependent soft robotic systems to resist the damage from uncertain factors in harsh environments. 展开更多
关键词 Soft gripper Untethered design Heat resistance Damage tolerance Impact mitigation
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Difunctional NH2-modified MOF supporting plentiful ion channels and stable LiF-rich SEI construction via organocatalysis for all-solid-state lithium metal batteries 认领 引用 被引量：4
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作者 Xuanyi Zhou Chenghan Li +4 位作者 Biao Zhang Fenfen Huang Pan Zhou Xinming Wang Zengsheng Ma 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2023年第5期140-148,共9页
As an essential part of the performance improvement of lithium metal batteries,the acquisition of dense(LiF-rich solid electrolyte interphase(SEI))has always been an urgent problem to be solved.Herein,we synthesized Z... As an essential part of the performance improvement of lithium metal batteries,the acquisition of dense(LiF-rich solid electrolyte interphase(SEI))has always been an urgent problem to be solved.Herein,we synthesized Zeolitic Imidazolate Frameworks(ZIFs)modified by two different functional groups(-NH2,-CH3)and used them as the fillers of polyethylene oxide(PEO)composite solid electrolytes to explore the catalytic effect of groups on LiF generation at the Li/electrolytes interface.In a LiFePO 4||SPE||Li cell test,the PEO-ZIF-NH2with LiF-rich SEI exhibits enhanced cycling performance,which was 3.8 times longer than that of PEO-ZIF-CH3.The formation mechanism of LiF-rich SEI was investigated using first-principles calculation,revealing that ZIFs-NH2makes the C-F bond in TFSI-longer compared with ZIFs-CH3,which leads to easier breakage of the C-F bond and promoted the formation of LiF.The simple design idea of using organic catalysis to generate more stable SEI provides a new aspect for preparing high-performance lithium metal batteries. 展开更多
关键词 LiF-rich SEI Organic catalysis Functional groups Hydrogen bond Difunctional MOF
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Verapamil inhibits scar formation after peripheral nerve repair in vivo 认领 引用 被引量：4
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作者 A-chao Han Jing-xiu Deng +4 位作者 Qi-shun Huang Huai-yuan Zheng Pan Zhou Zhi-wei Liu Zhen-bing Chen 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第3期508-511,共4页
The calcium channel blocker,verapamil,has been shown to reduce scar formation by inhibiting fibroblast adhesion and proliferation in vitro.It was not clear whether topical application of verapamil after surgical repai... The calcium channel blocker,verapamil,has been shown to reduce scar formation by inhibiting fibroblast adhesion and proliferation in vitro.It was not clear whether topical application of verapamil after surgical repair of the nerve in vivo could inhibit the formation of excessive scar tissue.In this study,the right sciatic nerve of adult Sprague-Dawley rats was transected and sutured with No.10-0 suture.The stoma was wrapped with gelfoam soaked with verapamil solution for 4 weeks.Compared with the control group（stoma wrapped with gelfoam soaked with physiological saline）,the verapamil application inhibited the secretion of extracellular matrix from fibroblasts in vivo,suppressed type I and III collagen secretion and increased the total number of axons and the number of myelinated axons.These findings suggest that verapamil could reduce the formation of scar tissue and promote axon growth after peripheral nerve repair. 展开更多
关键词 nerve regeneration nerve injury verapamil scar sciatic nerve type I collagen type III collagen neural regeneration
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Transfer of β-hydroxy-β-methylbutyrate from sows to their offspring and its impact on muscle fiber type transformation and performance in pigs 认领 引用 被引量：2
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作者 Haifeng Wan Jiatao Zhu +9 位作者 Caimei Wu Pan Zhou Yong Shen Yan Lin Shengyu Xu Lianqiang Che Bin Feng Jian Li Zhengfeng Fang De Wu 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2017年第2期438-449,共12页
Background： Previous studies suggested that supplementation of lactating sows with β-hydroxy-β-methylbutyrate（HMB） could improve the performance of weaning pigs, but there were little information in the muscle fi... Background： Previous studies suggested that supplementation of lactating sows with β-hydroxy-β-methylbutyrate（HMB） could improve the performance of weaning pigs, but there were little information in the muscle fiber type transformation of the offspring and the subsequent performance in pigs from weaning through finishing in response to maternal HMB consumption. The purpose of this study was to determine the effect of supplementing lactating sows with HMB on skeletal muscle fiber type transformation and growth of the offspring during d 28 and180 after birth. A total of 20 sows according to their body weight were divided into the control（CON, n = 10） or HMB groups（HMB, n = 10）. Sows in the HMB group were supplemented with β-hydroxy-β-methylbutyrate calcium（HMB-Ca） 2 g/kg feed during d 1 to 27 of lactation. After weaning, 48 mixed sex piglets were blocked by sow treatment and fed standard diets for post-weaning, growing, finishing periods. Growth performance was recorded during d 28 to 180 after birth. Pigs were slaughtered on d 28（n = 6reatment） and 180（n = 6reatment） postnatal and the longissimus dorsi（LD） was collected, respectively.Results： The HMB-fed sows during lactation showed increased HMB concentration（P ＆lt; 0.05） in milk and LD of weaning piglets（P ＆lt; 0.05）. In addition, offsprings in HMB group had a higher finishing BW and lean percentage than did pigs in CON group（P ＆lt; 0.05）, meanwhile, compared with pigs from sows fed the CON diet, pigs from sows fed HMB diet showed higher type Ⅱ muscle fiber cross-sectional area（CSA）, elevated myosin heavy chain（MyHC） Ⅱb and Sox6 mRNA, and fast-MyHC protein levels in LD（P ＆lt; 0.05）.Conclusions： HMB supplemented to sow diets throughout lactation increases the levels of HMB in maternal milk and skeletal muscle of pigs during d 28 after birth and promotes subsequent performance of pigs between d 28 and 180 of age by enhancing glycolytic muscle fiber transformation. 展开更多
关键词 β-hydroxy-β-methylbutyrate Lactating sow Muscle fiber Offspring Performance
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自主水下航行器核心功能载荷分析 认领 引用
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作者 邵星 潘州 +1 位作者 张新龙 叶子云 《舰船电子工程》 2025年第10期128-134,201,共7页
自主水下航行器(AUV)正朝向简约模块化、高效智能化方向发展,需要与之相适应的顶层设计概念。为实现AUV的通用系统架构设计、指导建立AUV关键技术实现路线谱图,对AUV的核心功能载荷进行了分析。调研并总结了多型典型AUV产品及其载荷设计... 自主水下航行器(AUV)正朝向简约模块化、高效智能化方向发展,需要与之相适应的顶层设计概念。为实现AUV的通用系统架构设计、指导建立AUV关键技术实现路线谱图,对AUV的核心功能载荷进行了分析。调研并总结了多型典型AUV产品及其载荷设计,对其基础技术指标、通信链路、探测及导航定位等功能载荷进行了对比分析,并归纳出AUV核心功能载荷分类;以调研结果为基础,选取其中一型AUV(Gavia AUV)作为分析案例,对其主要功能载荷及其技术架构进行了逐项分析,由此发掘出AUV的核心功能载荷设计要素。相关结果可用于支持模块化AUV设计,并为其核心载荷选定、整合、优化提供指导性依据。 展开更多
关键词 水下航行器 载荷 系统架构
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脓毒症的治疗进展 认领 引用 被引量：29
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作者 夏文芳 李冰玉 +3 位作者 林维山 潘舟 邓志敏 张勇刚 《医学综述》 CAS 2019年第11期2169-2175,共7页
脓毒症是一种临床常见的危重疾病,具有发病率高、发病机制复杂、病情严重和病死率高的特点。其本质为由感染引发的宿主免疫反应失调,并表现为由此导致的威胁生命的器官功能障碍的临床综合征。自1991年脓毒症的概念出现至今,脓毒症一直... 脓毒症是一种临床常见的危重疾病,具有发病率高、发病机制复杂、病情严重和病死率高的特点。其本质为由感染引发的宿主免疫反应失调,并表现为由此导致的威胁生命的器官功能障碍的临床综合征。自1991年脓毒症的概念出现至今,脓毒症一直是重症医学领域的一个热点和前沿问题。目前,临床常用的脓毒症治疗方法主要有液体治疗与复苏、抗感染治疗和血流动力学支持。未来,应用抗菌肽、免疫疗法、中医中药治疗等治疗方法可能成为脓毒症治疗的新方向。 展开更多
关键词 脓毒症 免疫疗法 中医中药治疗
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新型一维偏移耦合映像格系统及其动态特性 认领 引用 被引量：4
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作者 赵耿 潘周 +1 位作者 马英杰 董有恒 《计算机应用研究》 CSCD 北大核心 2023年第11期3289-3293,3302,共5页
混沌系统具有复杂的动力学行为,但在数字系统中运行时会出现动力学特性退化的问题。元胞自动机在时间、空间上都具有离散性,能够有效减弱混沌系统在有限精度下的动力学退化问题。基于元胞自动机,提出了一种一维偏移耦合映像格系统,利用... 混沌系统具有复杂的动力学行为,但在数字系统中运行时会出现动力学特性退化的问题。元胞自动机在时间、空间上都具有离散性,能够有效减弱混沌系统在有限精度下的动力学退化问题。基于元胞自动机,提出了一种一维偏移耦合映像格系统,利用初等元胞自动机每次更新的不同状态,动态产生每个格子的耦合索引偏移量,再根据偏移量对混沌序列施加不同的扰动,然后交替切换元胞自动机的迭代规则。最后,对混沌系统的动力学特性进行对比分析以及对该系统产生的时间序列进行量化和随机性检测,仿真实验结果表明,该混沌系统周期更长,遍历性更好,产生的序列随机性更佳,在序列密码算法中有很大的应用价值。 展开更多
关键词 混沌 元胞自动机 耦合映像格子 序列密码 Lyapunov指数
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