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Effects of TiB2 on microstructure,mechanical properties,and fluidity of AlSi10MnMg alloy fabricated by high-pressure die casting 认领 引用
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作者 Lei Liu Wei-xiao Yang +8 位作者 Kai Zhao Yan-qiang Li Tao Zhang Ying Fu Zhi-rou Zhang En-yu Guo Hui-jun Kang Zong-ning Chen Tong-min Wang 《China Foundry》 SCIE EI CAS CSCD 2026年第3期396-406,共11页
Optimizing the mechanical properties and fluidity of hypoeutectic Al-Si alloys in high-pressure die casting(HPDC)is critical for manufacturing thin-walled components with large sizes.The performance and fluidity of ca... Optimizing the mechanical properties and fluidity of hypoeutectic Al-Si alloys in high-pressure die casting(HPDC)is critical for manufacturing thin-walled components with large sizes.The performance and fluidity of castings over long flow distances depend on the precise control of solidification behavior during the complex HPDC process.In this study,an AlSi10 MnMg alloy was fabricated using a fluidity test mold with three channels of different thicknesses to investigate the influence of varying TiB2 content on the microstructure,mechanical properties,and fluidity of the alloy during long-distance filling in HPDC.Results indicate that the addition of 0.018 wt.%TiB2 significantly reduces externally solidified crystals(ESCs)and porosity contents,improving the filling distance from 1,700 mm to 1,833 mm.The reduction in ESCs in the castings by TiB2 is attributed to its ability to promote the migration of ESCs from the shot sleeve toward the melt center,where temperature and flow velocity are higher.At a filling distance of 1,300 mm,the ultimate tensile strength(UTS),yield strength(YS),and elongation increase notably with addition of 0.018 wt.%TiB2.When the addition of TiB2 increases to 0.036 wt.%,the area fraction of ESCs in the channel increases compared to that with 0.018 wt.%,and the filling distance slightly decreases to 1,796.9 mm.The mechanical properties of the alloy with 0.036 wt.%TiB2 are better than those of the alloy with 0.018 wt.%TiB2 over short distances,but become inferior beyond 1,000 mm.This work reveals the role of TiB2 in regulating solidification and flow during long-range filling,offering new insights into the processability of HPDC Al-Si alloys. 展开更多
关键词 high-pressure die casting TiB2 AlSi10MnMg fluidity mechanical properties
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High pressure die casting of aluminum alloys:A fluidity-centric review 认领 引用
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作者 Zu-nian He Yi-xian Liu +3 位作者 Peng-zhan Wang Saria Akhtar Zhi-hong Jia Shou-mei Xiong 《China Foundry》 SCIE EI CAS CSCD 2026年第4期485-514,共30页
Fluidity is one of the critical indicators for evaluating castability and has become a major research focus over the past five years due to advancements in high pressure die casting(HPDC)technology.Aluminum alloys,whi... Fluidity is one of the critical indicators for evaluating castability and has become a major research focus over the past five years due to advancements in high pressure die casting(HPDC)technology.Aluminum alloys,which were widely used in HPDC,offer promising structural and functional properties.The variables affecting the fluidity of alloy determine the solidification mode and the behavior of liquid flow,which forms the fundamental basis for understanding and controlling the macroscopic flow length.Here,an up-to-date and comprehensive review of research on fluidity of HPDC aluminum alloys is provided.It begins by discussing the main variables affecting fluidity,such as shot phases,compositions,solidification mode,and flow regime transition.The discussion then presents a summary of the recently proposed flow choking mechanisms.Additionally,algorithms related to fluidity under HPDC are reviewed,with particular emphasis on the increasing application of machine learning techniques in recent years.Finally,remaining challenges and perspectives for future materials,processes,and applications in HPDC fluidity research are proposed. 展开更多
关键词 fluidity high pressure die casting aluminum alloys models algorithms
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Role of preservation conditions on enrichment and fluidity maintenance of medium to high maturity lacustrine shale oil 认领 引用 被引量：3
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作者 ZHAO Wenzhi LIU Wei +9 位作者 BIAN Congsheng LIU Xianyang PU Xiugang LU Jiamin LI Yongxin LI Junhui LIU Shiju GUAN Ming FU Xiuli DONG Jin 《Petroleum Exploration and Development》 SCIE 2025年第1期1-16,共16页
In addition to the organic matter type,abundance,thermal maturity,and shale reservoir space,the preservation conditions of source rocks play a key factor in affecting the quantity and quality of retained hydrocarbons ... In addition to the organic matter type,abundance,thermal maturity,and shale reservoir space,the preservation conditions of source rocks play a key factor in affecting the quantity and quality of retained hydrocarbons in source rocks of lacustrine shale,yet this aspect has received little attention.This paper,based on the case analysis,explores how preservation conditions influence the enrichment of mobile hydrocarbons in shale oil.Research showns that good preservation conditions play three key roles.(1)Ensure the retention of sufficient light hydrocarbons(C1–C13),medium hydrocarbons(C14–C25)and small molecular aromatics(including 1–2 benzene rings)in the formation,which enhances the fluidity and flow of shale oil;(2)Maintain a high energy field(abnormally high pressure),thus facilitating the maximum outflow of shale oil;(3)Ensure that the retained hydrocarbons have the miscible flow condition of multi-component hydrocarbons(light hydrocarbons,medium hydrocarbons,heavy hydrocarbons,and heteroatomic compounds),so that the heavy hydrocarbons(C25+)and heavy components(non-hydrocarbons and asphaltenes)have improved fluidity and maximum flow capacity.In conclusion,in addition to the advantages of organic matter type,abundance,thermal maturity,and reservoir space,good preservation conditions of shale layers are essential for the formation of economically viable shale oil reservoirs,which should be incorporated into the evaluation criteria of shale oil-rich areas/segments and considered a necessary factor when selecting favorable exploration targets. 展开更多
关键词 medium-to-high maturity lacustrine shale oil mobile hydrocarbon enrichment preservation conditions stratum energy field miscible hydrocarbon component retained hydrocarbon fluidity Songliao Basin Ordos Basin Junggar Basin Bohai Bay Basin
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Effect of pouring and mold temperatures on fluidity and hot tearing behavior of cast Al-Li-Cu-Mg-Sc-Zr-Ti alloy 认领 引用 被引量：2
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作者 Yi-xiao WANG Guo-hua WU +4 位作者 Liang ZHANG You-jie GUO Xin TONG Liang-bin LI Xun-man XIONG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2025年第3期669-683,共15页
The influence of pouring temperature and mold temperature on the fluidity and hot tearing behavior of Al-2Li-2Cu-0.5Mg-0.15Sc-0.1Zr-0.1Ti alloys was investigated by experimental investigation and simulation assessment... The influence of pouring temperature and mold temperature on the fluidity and hot tearing behavior of Al-2Li-2Cu-0.5Mg-0.15Sc-0.1Zr-0.1Ti alloys was investigated by experimental investigation and simulation assessment.The results showed that the length of the spiral fluidity sample increases from 302 to 756 mm as the pouring temperature increases from 680 to 740℃,and from 293 to 736 mm as the mold temperature increases from 200 to 400℃.The hot tearing susceptibility(HTS)firstly decreases and then increases with increasing pouring and mold temperatures,which is mainly caused by the oxide inclusion originating from the high activity of Li at excessive pouring temperature.Excessive pouring and mold temperatures easily produce oxide inclusions and holes,leading to a reduction in fluidity and an increase in HTS of the alloy.Combining the experimental and simulation results,the optimized pouring and mold temperatures are~720℃ and~300℃ for the cast Al-Li alloy,respectively. 展开更多
关键词 pouring temperature mold temperature fluidity hot tearing behavior cast Al−Li alloy numerical simulation
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Influence of minor cerium addition on microstructure and fluidity of as-cast Al-Cu-Mn-Mg alloy 认领 引用 被引量：1
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作者 Yishan Wang Yu Bai +3 位作者 Kaixi Jiang Wenxue Fan Puxuan Wang Hai Hao 《Journal of Rare Earths》 SCIE EI CAS CSCD 2025年第2期377-383,I0006,共7页
Al-Cu-Mn alloys are widely used to produce automobile components like cylinder heads and engine blocks because of their capability to retain excellent thermal and mechanical characteristics at high temperatures.Howeve... Al-Cu-Mn alloys are widely used to produce automobile components like cylinder heads and engine blocks because of their capability to retain excellent thermal and mechanical characteristics at high temperatures.However,the Al-Cu-Mn-based alloys demonstrate restricted fluidity,leading to casting defects such as shrinkage and incomplete filling.This research investigated the microstructure and fluidity of Al-4.7Cu-1.0Mn-0.5Mg(wt%)alloy with minor cerium(Ce)addition.The as-cast alloys predominantly compriseα-Al matrix,accompanied by the presence of Al2Cu,Al6Mn,and Al8Cu4Ce phases.The influence of adding Ce on the fluidity of the Al-4.7Cu-1.0Mn-0.5Mg alloy was investigated using a trispiral fluidity test mold in this research.The findings suggest that the addition of Ce within the range of 0.1 wt%to 0.5 wt%in the Al-4.7Cu-1.0Mn-0.5Mg alloy results in an enhancement in fluidity.Specifically,the alloy containing 0.4 wt%Ce exhibits a significant increase in fluidity distance,from 349.7 to 485.7 mm.This improvement can be attributed to the reduction in viscosity,the refinement of secondary dendrite arm spacing,and the modification of secondary phase particles.However,a higher concentration of Ce leads to a decrease in fluidity length,potentially due to the formation of Al8Cu4Ce. 展开更多
关键词 Al-Cu-Mn-Mg alloy Rare earths Ce addition Microstructure Fluidity
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Optimizing the fluidity in thin-section investment casting for vacuum induction molten AZ91D-1 wt.% CaO 认领 引用
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作者 V.H.Carneiro V.Lopes +1 位作者 I.Duarte H.Puga 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2025年第6期2845-2854,共10页
This paper discusses an experimental investigation into the fluidity of AZ91D-1 wt.%Ca O magnesium melt via induction for thin-section investment casting.Plaster molds with thin spiral cavities(0.5 to 1.5 mm square se... This paper discusses an experimental investigation into the fluidity of AZ91D-1 wt.%Ca O magnesium melt via induction for thin-section investment casting.Plaster molds with thin spiral cavities(0.5 to 1.5 mm square sections)were designed and manufactured to assess the impact of casting conditions on filling length,as magnesium alloys cause severe melting and melt-mold exothermic reactions,making investment casting challenging.Combinations of traditional Mg-mold reaction mitigation techniques,such as applying a protective mold coating(Yttria)and vacuum,were examined to determine their role in the filling process.The results suggest that when induction is employed to melt reactive alloys,these methods are not always beneficial,as initially thought.Particularly at higher melt temperatures,the combination of Yttria-coated molds with low-pressure vacuum induction significantly reduce fluidity:vacuum induced melt levitation which promotes oxidation with the residual atmosphere;and Yttria-coating cracking due to thermal stress during the mold fabrication slows filling and promotes significant melt-mold reaction.This study shows that best results to investment cast thin-sections are obtained by avoiding both vacuum and protective coatings,providing a viable route for the precision manufacturing of stent biomedical devices. 展开更多
关键词 AZ91D-1 wt.%CAO Fluidity Investment casting Yttria-coating Vacuum
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From solid to fluid: The possible role of tissue fluidity in mechanical stretch-induced tissue expansion 认领 引用
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作者 Shengzhou Shan Xusong Luo 《Chinese Journal of Plastic and Reconstructive Surgery》 2025年第1期56-58,共3页
Tissue expansion is a widely utilized technique in plastic and reconstructive surgery;however,the biological mechanisms underlying the skin response remain poorly understood.We propose that tissue fluidity,the transit... Tissue expansion is a widely utilized technique in plastic and reconstructive surgery;however,the biological mechanisms underlying the skin response remain poorly understood.We propose that tissue fluidity,the transition of tissue from a solid-like state to a fluid-like state,plays a pivotal role in enabling the reorganization of the epidermal structure and cellular spatial order,which is essential for effective tissue expansion.Drawing parallels between fluidity in materials science and biological systems,we suggest that the fluid-like behavior in the skin may be critical for mechanical adaptability.Understanding the influence of tissue fluidity may open pathways for modulating this process,potentially enhancing tissue expansion efficiency,reducing procedural duration,and improving clinical outcomes.This perspective highlights the importance of investigating the biological dynamics of tissue fluidity and exploring the potential for targeted manipulation of fluidity-related pathways to optimize tissue expansion.Such advancements could profoundly affect regenerative and reconstructive surgical practices. 展开更多
关键词 Tissue expansion Tissue fluidity Mechanical stretch Epidermis
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Effect of polypropylene fiber and coarse aggregate on the ductility and fluidity of cemented tailings backfill 认领 引用 被引量：15
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作者 YAN Rong-fu LIU Jia-ming +3 位作者 YIN Sheng-hua ZOU Long KOU Yong-yuan ZHANG Peng-qiang 《Journal of Central South University》 SCIE EI CAS CSCD 2022年第2期515-527,共13页
Adding polypropylene(PP)fibers and coarse aggregates has become a popular way to enhance the strength and stability of the cemented tailings backfilling(CTB)body.It is essential to explore the influence of tailings-ag... Adding polypropylene(PP)fibers and coarse aggregates has become a popular way to enhance the strength and stability of the cemented tailings backfilling(CTB)body.It is essential to explore the influence of tailings-aggregate ratio and fiber content on the mechanical properties of CTB samples.The comprehensive tests of the unconfined compressive strength(UCS),slump and microstructure were designed,and the regression models were established to characterize the effect of the strength,ductility and fluidity.The results indicate that the tailings-aggregate ratio of 5:5 and PP fiber content of 0.5 kg/m3 are the optimum point considering the UCS,cracking strain,peak strain and post-peak ductility.The tailings-aggregate ratio is consistent with the unary quadratic to the UCS and a linear model with a negative slope to the slump.Microstructural analysis indicates that PP fiber tends to bridge the cracks and rod-mill sand to serve as the skeleton of the paste matrix,which can enhance the compactness and improve the ductility of the CTB.The results presented here are of great significance to the understanding and application of coarse aggregates and fibers to improve the mechanical properties of CTB. 展开更多
关键词 cemented tailings backfill polypropylene fiber coarse aggregate unconfined compressive strength postpeak ductility fluidity
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Versatile fluidity test model for cast superalloys and comparison between IN718 and IN939 认领 引用 被引量：4
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作者 Jun ZHANG Zi-qi JIE +1 位作者 Miao-nan LIU Min GUO 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2024年第9期2881-2888,共8页
A spiral fluidity test model of superalloys with 10 mm in height and 3 mm in thickness was designed to evaluate the fluidity of two distinct Ni-based superalloys IN718 and IN939.The factors influencing fluidity are as... A spiral fluidity test model of superalloys with 10 mm in height and 3 mm in thickness was designed to evaluate the fluidity of two distinct Ni-based superalloys IN718 and IN939.The factors influencing fluidity are ascertained through comparative analysis utilizing methodologies such as JMat Pro,differential scanning calorimetry and high-temperature confocal laser scanning microscopy.The results show that under identical testing conditions,the fluidity of the IN939 superalloy surpasses that of the IN718 superalloy.When subjected to the same temperature,the melt viscosity and surface tension of IN939 superalloy are considerably reduced relative to those of IN718 superalloy,which is beneficial to improving the melt fluidity.Furthermore,the liquidus temperature and solidification range for the IN939 superalloy are both smaller compared with those of the IN718 superalloy.This condition proves advantageous in delaying dendrite coherency,thereby improving fluidity. 展开更多
关键词 fluidity solidification range superalloys surface tension viscosity
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Simultaneously improving thermal conductivity,mechanical properties and metal fluidity through Cu alloying in Mg-Zn-based alloys 认领 引用 被引量：4
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作者 Yuntao Zhang Wei Liu +3 位作者 Weipeng Chen Zhiqiang Li Hua Hou Yuhong Zhao 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第9期3823-3839,共17页
Mg-Zn-based alloys have been widely used in computer,communication,and consumer(3C)products due to excellent thermal conductivity.However,it is still a challenge to balance their mechanical performance and thermal con... Mg-Zn-based alloys have been widely used in computer,communication,and consumer(3C)products due to excellent thermal conductivity.However,it is still a challenge to balance their mechanical performance and thermal conductivity.Here,we investigate microstructure,mechanical performance,thermal conductivity and metal fluidity of Mg-5Zn(wt.%)alloy after Cu alloying by experimental and simulation methods.First,Mg-5Zn alloy consist ofα-Mg matrix and interdendritic MgZn phases.As the Cu content increases,however,MgZn phases disappear but intragranular Mg2Cu and interdendritic MgZnCu phases appear in Mg-5Zn-Cu alloys.Besides,the grain size ofα-Mg phase is refined and the volume fraction of MgZnCu phase increases as the Cu content increases.Second,Cu addition is found to improve thermal conductivity of Mg-5Zn alloy remarkably.Especially,Mg-5Zn-4Cu alloy exhibits the best thermal conductivity of 124 W/(m·K),which is mainly due to the significant reduction in both solid solubility of Zn in theα-Mg matrix and lattice distortion ofα-Mg matrix.Moreover,a stable crystal structure of MgZnCu phase also contributes to an increased thermal conductivity based on first principles and molecular dynamics simulations.Third,Cu addition simultaneously enhances strength and ductility of Mg-5Zn alloy.Tensile yield strength and elongation of Mg-5Zn-6Cu alloy reach 117 MPa and 18.0%,respectively,which is a combined result of refinement,solution,second phase,and dislocation strengthening.Finally,combined with a phase field simulation,we found that Cu addition enhances metal fluidity of Mg-5Zn alloy.On the one hand,Cu alloying not only delays dendrite growth but also prolongs solidification time.On the other hand,MgZnCu phase stabilizes the dendrite growth of theα-Mg phases by reducing energy consumption during solidification of liquid metal.This work demonstrates that Cu alloying is an ideal strategy for synergistically improving the thermal conductivity,mechanical performance and metal fluidity of Mg-based alloys. 展开更多
关键词 Mg-Zn-Cu alloy Phase field Molecular dynamics Thermal conductivity Metal fluidity
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Evaluation of casting fluidity and filling capacity of Zr-based amorphous metal melts 认领 引用 被引量：2
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作者 De-qiang Ma Xiao-zhao Ma +3 位作者 Hong-yuan Zhang Ming-zhen Ma Xin-yu Zhang Ri-ping Liu 《Journal of Iron and Steel Research International》 SCIE EI CAS CSCD 2018年第11期1163-1171,共9页
Understanding the flow characteristics of amorphous metal melts is important for casting and molding processes.Fluidity of Zr-based amorphous metal melts was determined by using a self-designed apparatus.Phase analysi... Understanding the flow characteristics of amorphous metal melts is important for casting and molding processes.Fluidity of Zr-based amorphous metal melts was determined by using a self-designed apparatus.Phase analysis demonstrated that the fluidity test samples were fuUy amorphous structure.The onset crystallization temperature significantly moved toward high temperature with the increases of casting temperature,which improved the glass-forming ability and thermal stability of Zr-based amorphous metal.Fluidity test results demonstrated that the fluidity length increased monotonically with the increases of temperature,pressure,and runner diameter.By identifying the types and quantities of the defect in castings,it could conclude that smooth filling processes occurred under appropriate conditions.Experimental results indicated that the flow behavior of the Zr-based amorphous metal melts strongly depended on the casting temperature and equivalent thickness.Constitutive equation based on Newton's law of heat exchange and Rayleigh rule was established to'evaluate the fluidity of Zr-based amorphous metal melts.Theoretical calculations and experimental tests were basically coincided with each other.The determined optimal casting temperatures and equivalent thicknesses were adopted to successfully fabricate a series of fully shaped castings through gravity casting. 展开更多
关键词 Amorphous metal melt Casting Fluidity Constitutive equation Filling capacity
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Effects of BYHW Decoction and Its Effective Constituents on the Fluidity of the Cell Membrane in a Stroke-Modeled Rat Brain 认领 引用 被引量：5
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作者 卢景芬 李晨旭 +4 位作者 古力努尔 李廷凤 屠鹏飞 殷俊杰 蔡少青 《Journal of Chinese Pharmaceutical Sciences》 CAS 2002年第4期132-136,共5页
With in vitro spin labeling electron spin resonance (ESR) spectroscopy, we have studied the effects of Bu Yang Huan Wu (BYHW) decoction and its effective constituents such as astragaloside IV ferulic acid, chuanxiongz... With in vitro spin labeling electron spin resonance (ESR) spectroscopy, we have studied the effects of Bu Yang Huan Wu (BYHW) decoction and its effective constituents such as astragaloside IV ferulic acid, chuanxiongzine, rutin, chlorogenic acid, 9,10 dimethoxy pterocarpane 7 O β D glucoside, calycosin, formononetin, calycosin 7 O glucoside, paeoniflorin, paeonal and quercein on the cell membrane fluidity of a rat brain which was modeled after the dual cervical arteries were intercepted and released for realizing an ischemia reperfusion injury which was selected as a brain stroke model. Our results indicated that the cell membrane fluidity in the model group decreased approximately 8% compared with the control group, and after brain cells were incubatied with species, the membrane fluidity could be recovered closely to the control level depending on the BYHW decoction and its different constituents. As the membrane fluidity is a very sensitive biological index which reflectsd the cell status, our method will be useful to study the molecular mechanism of tradition Chinese medicine (TCM) and its combination recipe. 展开更多
关键词 Bu Yang Huan Wu decoction Brain stroke Cell membrane fluidity ESR
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Effect of fluidity on the manufacturing of open cell magnesium alloy foams 认领 引用 被引量：3
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作者 Xue-Zheng Yue Koichi Kitazono +1 位作者 Xue-Jie Yue Bo-Young Hur 《Journal of Magnesium and Alloys》 SCIE CAS 2016年第1期1-7,共7页
The effect of fluidity on open cell AZ31 metal foam samples fabricated using a solid state space holder method was investigated.Granule was fabricated by plaster powder and perlite powder.Granules were sieved which co... The effect of fluidity on open cell AZ31 metal foam samples fabricated using a solid state space holder method was investigated.Granule was fabricated by plaster powder and perlite powder.Granules were sieved which compacted layer by layer in casting mold.Preforms which made by granules were then heated to 200℃,300℃,400℃,500℃ under a rough(mechanical)vacuum before pressure infiltration with AZ31 Mg alloy.Samples were infiltrated using vacuum pressure values range of 8-14 KPa.The conditions of pressure and temperature were performed in order to get different fluidity on manufacturer of open cell AZ31 metal foam specimen quantity.It is found that the fluidity plays significant role to determine the open cell AZ31 alloy foam.The fluidity is affected by preheat temperature and infiltration vacuum pressure.The macrostructure,the distribution of the pores,microstructure,infiltration length,and porosity were investigated. 展开更多
关键词 Magnesium alloy Fluidity Open cell Vacuum
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Epigallocatechin-3-gallate affects the growth of LNCaP cells via membrane fluidity and distribution of cellular zinc 认领 引用 被引量：2
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作者 Jun-guo YANG Hai-ning YU +5 位作者 Shi-li SUN Lan-cui ZHANG Guo-qing HE Undurti N. DAS Hui RUAN Sheng-rong SHEN 《Journal of Zhejiang University-SCIENCE B》 SCIE CAS 2009年第6期411-421,共11页
Objective:To evaluate effects of epigallocatechin-3-gallate (EGCG) on the viability, membrane properties, and zinc distribution, with and without the presence of Zn2+, in human prostate carcinoma LNCaP cells. Methods:... Objective:To evaluate effects of epigallocatechin-3-gallate (EGCG) on the viability, membrane properties, and zinc distribution, with and without the presence of Zn2+, in human prostate carcinoma LNCaP cells. Methods: We examined changes in cellular morphology and membrane fluidity of LNCaP cells, distribution of cellular zinc, and the incorporated portion of EGCG after treatments with EGCG, Zn2+, and EGCG+Zn2+. Results: We observed an alteration in cellular morphology and a decrease in membrane fluidity of LNCaP cells after treatment with EGCG or Zn2+. The proportion of EGCG incorporated into liposomes treated with the mixture of EGCG and Zn2+ at the ratio of 1:1 was 90.57%, which was significantly higher than that treated with EGCG alone (30.33%). Electron spin resonance (ESR) studies and determination of fatty acids showed that the effects of EGCG on the membrane fluidity of LNCaP were decreased by Zn2+. EGCG accelerated the accumulation of zinc in the mitochondria and cytosol as observed by atomic absorption spectrometer. Conclusion: These results show that EGCG interacted with cell membrane, decreased the membrane fluidity of LNCaP cells, and accelerated zinc accumulation in the mitochondria and cytosol, which could be the mechanism by which EGCG inhibits proliferation of LNCaP cells. In addition, high concentrations of Zn2+ could attenuate the actions elicited by EGCG. 展开更多
关键词 Epigallocatechin-3-gallate （EGCG） Zinc LNCaP Membrane fluidity
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Differential effects of insecticides on mitochondrial membrane fluidity and ATPase activity between the wolf spider and the rice stem borer 认领 引用 被引量：12
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作者 LI Hai-ping CHANG Jing +1 位作者 FENG Tao GAO Xi-wu 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2015年第12期2574-2580,共7页
Differential effects of methamidophos and three pyrethroids on ATPase activity and membrane fluidity of mitochondria were investigated between the wolf spider（Pirata subpiraticus（Boes.et Str.））and the rice stem bo... Differential effects of methamidophos and three pyrethroids on ATPase activity and membrane fluidity of mitochondria were investigated between the wolf spider（Pirata subpiraticus（Boes.et Str.））and the rice stem borer（Chilo suppressalis（Walker））.Based on a comparison of LD_（50） values,the toxicities of the tested insecticides were higher to the wolf spider than to the rice stem borer.Cyhalothrin at 1×10^（–4） mmol L^（–1） caused inhibition of the mitochondrial Na~＋-K~＋-ATPase and Ca^（2＋）-Mg^（2＋）-ATPase activities,and it’s inhibitions on Na＋-K＋-ATPase and Ca^（2＋）-Mg^（2＋）-ATPase activities were significantly higher in the wolf spider（44 and 28%）than in the rice stem borer（19 and 11%）.Methamidophos at 1×10^（–4） mmol L^（–1） decreased Ca^（2＋）-Mg^（2＋）-ATPase activity by 16 and 27%in the wolf spider and the rice stem borer,respectively,but no significant effect on the specific activity of Na＋-K＋-ATPase was observed.The DPH（1,6-diphenyl-1,3,5-hexatriene）fluorescence polarization values of mitochondrial membranes were not significantly affected by methamidophos in either species.However,cyhalothrin and alpha-cypermethrin induced the values of DPH polarization of mitochondrial membrane increasing with the concentration of cyhalothrin and alpha-cypermethrin from 20 to 100μmol L^（–1） in the rice stem borer and the wolf spider.Effect of ethofenprox on fluidity of the wolf spider and the rice stem borer was contrary.These results suggest that both inhibition of membrane ATPase and changes of membrane fluidity could be appended to the action mechanisms of pyrethroid insecticides. 展开更多
关键词 pyrethroids membrane fluidity ATPase wolf spider rice stem borer
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Effects of Organosilane-modified PCE on the Fluidity and Hydration Properties of Cement-Fly Ash Composite Binder 认领 引用 被引量：1
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作者 HE Yan LIU Shuhua +2 位作者 JI Tao KONG Yaning SHUI Liangliang 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2020年第6期1081-1089,共9页
Effects of organosilane-modified PCE (OS-PCE) on the fluidity and the hydration properties of cement-fly ash (FA) composite binder were systematically analyzed.The experimental results show that OS-PCE possesses respe... Effects of organosilane-modified PCE (OS-PCE) on the fluidity and the hydration properties of cement-fly ash (FA) composite binder were systematically analyzed.The experimental results show that OS-PCE possesses respectively 36.98% and 36.67% higher saturated adsorption amount on cement and FA,in comparison with ordinary PCE,and can contribute to higher fluidity of cement-FA composite binder.The addition of OS-PCE retards hydration process of cement-FA composite binder proportionally with the dosage of OS-PCE,but promotes the hydration kinetics of the composite binder.The reactivity enhancement is attributed to the well-dispersed FA by OS-PCE,which provides more nucleation sites for the reaction of heterogeneous C-S-H and enhances the contact with water to react with CH forming pozzolanic C-S-H.Well-distributed hydration products are exhibited in the hardened binder added with OS-PCE,with a large number of hydrated gels uniformly fill in the pores and gaps,which improves the compaction of the hardened structure. 展开更多
关键词 cement fly ash organosilane-modified PCE fluidity hydration properties
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Changes of cell membrane fluidity for mesenchymal stem cell spheroids on biomaterial surfaces 认领 引用 被引量：2
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作者 Chui-Wei Wong Hao-Wei Han Shan-hui Hsu 《World Journal of Stem Cells》 SCIE 2022年第8期616-632,共17页
BACKGROUND The therapeutic potential of mesenchymal stem cells(MSCs)in the form of threedimensional spheroids has been extensively demonstrated.The underlying mechanisms for the altered cellular behavior of spheroids ... BACKGROUND The therapeutic potential of mesenchymal stem cells(MSCs)in the form of threedimensional spheroids has been extensively demonstrated.The underlying mechanisms for the altered cellular behavior of spheroids have also been investigated.Cell membrane fluidity is a critically important physical property for the regulation of cell behavior,but it has not been studied for the spheroid-forming cells to date.AIM To explore the association between cell membrane fluidity and the morphological changes of MSC spheroids on the surface of biomaterials to elucidate the role of membrane fluidity during the spheroid-forming process of MSCs.METHODS We generated three-dimensional(3D)MSC spheroids on the surface of various culture substrates including chitosan(CS),CS-hyaluronan(CS-HA),and polyvinyl alcohol(PVA)substrates.The cell membrane fluidity and cell morphological change were examined by a time-lapse recording system as well as a highresolution 3D cellular image explorer.MSCs and normal/cancer cells were prestained with fluorescent dyes and co-cultured on the biomaterials to investigate the exchange of cell membrane during the formation of heterogeneous cellular spheroids.RESULTS We discovered that vesicle-like bubbles randomly appeared on the outer layer of MSC spheroids cultured on different biomaterial surfaces.The average diameter of the vesicle-like bubbles of MSC spheroids on CS-HA at 37℃ was approximately 10μm,smaller than that on PVA substrates(approximately 27μm).Based on time-lapse images,these unique bubbles originated from the dynamic movement of the cell membrane during spheroid formation,which indicated an increment of membrane fluidity for MSCs cultured on these substrates.Moreover,the membrane interaction in two different types of cells with similar membrane fluidity may further induce a higher level of membrane translocation during the formation of heterogeneous spheroids.CONCLUSION Changes in cell membrane fluidity may be a novel path to elucidate the complicated physiological alterations in 3D spheroid-forming cells. 展开更多
关键词 Cell membrane fluidity Cell-cell interaction Cellular spheroids Chitosan Hyaluronan
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Effect of Holding Time on Thixotropic Fluidity of Semi-solid AZ91D Magnesium Alloy 认领 引用 被引量：7
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作者 Zesheng JI Maoliang HU Xiaoping ZHENG 《Journal of Materials Science & Technology》 SCIE EI CAS 2007年第2期247-252,共6页
To investigate the thixotropic fluidities, microstructures and mechanical properties of semi-solid AZ91D magnesium alloy during reheating, a self-made die set with channels of different sizes were used. The results sh... To investigate the thixotropic fluidities, microstructures and mechanical properties of semi-solid AZ91D magnesium alloy during reheating, a self-made die set with channels of different sizes were used. The results show that critical forming forces and maximal forming forces could be obtained and related to the holding times in the semi-solid forming process. In the holding time of 0-2700 s, with increasing the holding time, maximal forming force decreased sharply and critical forming force decreased slowly. In the whole thixotropic flowing process, the filling-in was steady and the surface fineness was good. The forming force increased when the slurry changed the flowing direction or flowed from the big-diameter chamber to the small-diameter one. The tensile strength and elongation to failure of the sample after holding time for 2700 s, compared to as-cast sample, are increased by approximately 42.7% and 180%, respectively, and the fractured surfaces presented dimple-like pattern. 展开更多
关键词 AZ91D magnesium alloy Semi-solid Thixotropic fluidity Microstructure
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Relationship Between H^+-ATPase Activity and Fluidity of Tonoplast in Barley Roots Under NaCl Stress 认领 引用 被引量：23
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作者 章文华 陈沁 刘友良 《Acta Botanica Sinica》 2002年第3期292-296,共5页
H +_ATPase activity of tonoplast in roots of Hordeum vulgare L. cv. 'Tanyin 2' (salt_tolerant cultivar) increased when the roots were exposed to 50-200 mmol/L NaCl for 2 d, and decreased when NaCl concentratio... H +_ATPase activity of tonoplast in roots of Hordeum vulgare L. cv. 'Tanyin 2' (salt_tolerant cultivar) increased when the roots were exposed to 50-200 mmol/L NaCl for 2 d, and decreased when NaCl concentration was increased to 600 mmol/L. In 'Kepin 7' (salt_sensitive cultivar), tonoplast H +_ATPase activity in roots also increased at lower levels of NaCl (50-100 mmol/L), but decreased at higher levels of NaCl (200-600 mmol/L). Tonoplast fluidity in roots of 'Tanyin 2' decreased at 50-200 mmol/L NaCl, and increased significantly at 600 mmol/L NaCl. Under salt stress, the change of tonoplast fluidity was identical with that of the ratio of unsaturated fatty acids to saturated fatty acids in tonoplast lipid of barley roots. It is proposed that the increase of tonoplast fluidity due to increased degree of unsaturation of fatty acids is one of the reasons leading to the decrease of H +_ATPase activity under higher level of NaCl stress. 展开更多
关键词 salt stress H +_ATPase membrane fluidity fatty acid composition barley
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Effect of reinforcement amount, mold temperature, superheat, and mold thickness on fluidity of in-situ Al-Mg_2Si composites 认领 引用 被引量：3
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作者 Reza Vatankhah Barenji 《China Foundry》 SCIE CAS 2018年第1期66-74,共9页
In the present study, the effects of mold temperature, superheat, mold thickness, and Mg_2Si amount on the fluidity of the Al-Mg_2Si as-cast in-situ composites were investigated using the mathematical models. Composit... In the present study, the effects of mold temperature, superheat, mold thickness, and Mg_2Si amount on the fluidity of the Al-Mg_2Si as-cast in-situ composites were investigated using the mathematical models. Composites with different amounts of Mg_2Si were fabricated, and the fluidity and microstructure of each were then analyzed. For this purpose, the experiments were designed using a central composite rotatable design, and the relationship between parameters and fluidity were developed using the response surface method. In addition, optical and scanning electron microscopes were used for microstructural observation. The ANOVA shows that the mathematical models can predict the fluidity accurately. The results show that by increasing the mold temperature from 25℃ to 200℃, superheat from 50℃ to 250℃, and thickness from 3 mm to 12 mm, the fluidity of the composites decreases, where the mold thickness is more effective than other factors. In addition, the higher amounts of Mg_2Si in the range from 15 wt.% to 25 wt.% lead to the lower fluidity of the composites. For example, when the mold temperature, superheat, and thickness are respectively 100℃, 150℃, and 7 mm, the fluidity length is changed in the range of 11.9 cm to 15.3 cm. By increasing the amount of Mg_2Si, the morphology of the primary Mg_2Si becomes irregular and the size of primary Mg_2Si is increased. Moreover, the change of solidification mode from skin to pasty mode is the most noticeable microstructural effect on the fluidity. 展开更多
关键词 Al-Mg2Si composites microstructure fluidity
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