The emergence of avian inffllfluenza virus(AIVs)in seabird populations has intensiffiified in recent years,signaling a signiffiificant shift in host ecology and transmission dynamics.To address this,this study introdu...The emergence of avian inffllfluenza virus(AIVs)in seabird populations has intensiffiified in recent years,signaling a signiffiificant shift in host ecology and transmission dynamics.To address this,this study introduces the Terrestrial Bird-Seabird Co-occurrence Index(TSCI),a novel metric designed to assess the spatial and temporal cooccurrence between terrestrial bird and seabird AIV hosts.The TSCI demonstrates strong predictive performance(AUC=0.94),capturing over 84.10%of conffiifirmed seabirds AIV cases within global high-risk zones.Based on this,363 Mha of coastal wetlands(representing 2.44%of global land area)were identiffiified as high-risk terrestrial birds and seabirds contact interface,providing a robust tool for identifying high-risk zones of potential virus spillover at the“terrestrial birds and seabirds contact interface.”Our analysis highlights that temperate coastal regions,particularly in Europe,North America,and East Asia,exhibit high TSCI values.Wetland ecosystems serve as critical hotspots for virus spillover,emphasizing the need for habitat-speciffiific conservation and surveillance strategies.Our study offers a scalable tool to enhance targeted monitoring,guide resource allocation,and inform integrated policies for preventing zoonotic spillover from wild bird reservoirs under the One Health framework.展开更多
Conventional metallic current collectors in lithium-sulfur(Li-S)batteries suffer from high cost,corrosion,and poor compatibility with high-sulfur-loading electrodes.Here,we develop a current collector-free allcarbon h...Conventional metallic current collectors in lithium-sulfur(Li-S)batteries suffer from high cost,corrosion,and poor compatibility with high-sulfur-loading electrodes.Here,we develop a current collector-free allcarbon host to achieve high-performance Li-S systems.Graphene(Gr)nanosheets are in situ grown on carbon nanotubes(CNTs)via plasma-enhanced chemical vapor deposition(PECVD),forming Gr@CNTs heterojunctions that serve simultaneously as conductive frameworks and self-supporting hosts.This hierarchical architecture can effectively overcome the stacking and closure issues of each component.Thus-obtained Gr@CNTs host exhibits ultrafast polysulfide adsorption(within 5 s in 5 mmol L-1Li2S6solution)and enables uniform sulfur deposition,ensuring efficient charge transport and suppressed shuttle effect.Consequently,the all-carbon host Li-S batteries deliver a high capacity of 1609.32 mA h g-1at 0.2C and remarkable cycling stability with only 0.073%decay per cycle over 300 cycles at 5C,establishing a promising pathway toward lightweight,high-energy-density Li-S systems.展开更多
For Li metal battery,Li metal anodes severely suffer from dendritic growth due to heterogeneous electrodeposition,which inhibits their development and application.While extensive studies for Li dendrite suppression em...For Li metal battery,Li metal anodes severely suffer from dendritic growth due to heterogeneous electrodeposition,which inhibits their development and application.While extensive studies for Li dendrite suppression empirically utilize 3D hosts to homogenize the micro-scaled electric field within the host,the inherent correlation between host structure and electric field distribution and underlying principles remains elusive,and the corresponding design of hosts to enhance the electric effects remains challenging.Here,the host microstructure-electric field correlations are established via COMSOL simulations and demonstrate the enhanced redistribution of the electric field through structural redesign of hosts.Based on a structure model,an enhanced gradient electric field host(EGHx)with a supercontinuous gradient pore architecture is fabricated with the assistance of the porogen dissolution method,which achieves a self-leveling-like Li deposition through spatially programmed charge redistribution.Through further structural optimization,the EGH2(with 2 wt%porogen)exhibits an~98%Coulombic efficiency(CE)over 350 cycles(1 mA cm-2,1 mAh cm-2).Further multidimensional testing with argon protection reveals the role of the host in modulating solid-electrolyte interphase(SEI)composition.Accordingly,the EGH2 enables stable dendrite-free Li plating/stripping behaviors for 2100 h.The assembled full cell and pouch cell also display stable cycling performance with an LFP cathode.展开更多
The evolution of parasitic strategies through tracking host life-history patterns represents a key adaptive trait in avian brood parasites.However,when hosts successfully exploit human-modiffiified environments—such ...The evolution of parasitic strategies through tracking host life-history patterns represents a key adaptive trait in avian brood parasites.However,when hosts successfully exploit human-modiffiified environments—such as diverse and concealed nesting sites—the mechanisms enabling cuckoos(Cuculus spp.)to accurately locate and parasitize such nests remains unclear.The Daurian Redstart(Phoenicurus auroreus),a human-commensal secondary cavitynester,often breeds in diverse artiffiificial structures—leading to variable and concealed nest locations—making it an ideal system to study this question.Using long-term ffiifield monitoring and a nestbox attraction experiment,we investigated how Common Cuckoos(Cuculus canorus)locate and parasitize such concealed nests.Our results show no signiffiificant variation in Common Cuckoo parasitism rates across different natural nesting sites.However,nestboxes that were more exposed experienced higher parasitism rates than natural nests.Furthermore,cuckoos targeted exclusively those boxes with active host attendance,rather than boxes occupied by other species.This study provides the ffiifirst evidence of cuckoo parasitism on a human-associated host nesting indoors,underscoring the key role of host activity cues and suggesting that cuckoos,like their hosts,are also adapting to anthropogenic refuges.展开更多
Human metapneumovirus(hMPV)is a prevalent respiratory virus in children with acute lower respiratory tract infections that is highly homologous with respiratory syncytial virus(RSV),the primary etiological agent of pe...Human metapneumovirus(hMPV)is a prevalent respiratory virus in children with acute lower respiratory tract infections that is highly homologous with respiratory syncytial virus(RSV),the primary etiological agent of pediatric upper and lower respiratory tract infections.Although hMPV and RSV are the only human pathogens within the Pneumoviridae family and share similar clinical manifestations,the mechanisms underlying their divergent pathogenicity remain poorly understood.In this study,we performed transcriptomic analysis on clinical respiratory samples collected between 2017 and 2019 from 61 children:including hMPV-infected,RSV-infected and healthy controls.This analysis revealed a shared upregulation of antiviral response pathways,including neutrophil activation and signaling mediated by interferons and interleukins.Conversely,cilium organization and assembly pathways were commonly downregulated in both infections.hMPV infection uniquely upregulated pathways associated with extracellular component activity,ion channel complexes,and neuroactive ligand‒receptor interactions.In contrast,pathways related to membrane rafts and membrane microdomains were uniquely downregulated in hMPV-infected patients.Analysis of differentially expressed immune-related and interferon-stimulated genes revealed significant hMPV-specific increases in EGF and FCGR1A,alongside decreased EPAS1 expression.The genes that were uniquely upregulated during hMPV infection were enriched in cytokine production regulation,cytokinecytokine receptor interactions,and PI3K/AKT signaling,whereas those that were uniquely downregulated involved the viral entry and endocytic vesicle pathways.Both hMPV infection and RSV infection significantly increased the proportions of M1 macrophages and neutrophils but decreased the proportions of M0 and M2 macrophages.Notably,hMPV infection resulted in a significant increase in monocytes and activated NK cells coupled with a decrease in resting memory CD4+T cells,compared with RSV infection.The results also revealed a significantly greater relative abundance of Prevotella salivae in the hMPV infection group,whereas Streptococcus salivarius and Streptococcus mitis were enriched in the RSV group.These distinct immune and microbial signatures provide novel insights into the pathogenesis of pediatric hMPV and RSV infections.展开更多
Fungi play crucial roles in nutrient acquisition,plant growth promotion,and the enhancement of resistance to both abiotic and biotic stresses.However,studies on the fungal communities associated with peas (Pisum sativ...Fungi play crucial roles in nutrient acquisition,plant growth promotion,and the enhancement of resistance to both abiotic and biotic stresses.However,studies on the fungal communities associated with peas (Pisum sativum L.) remain limited.In this study,we systematically investigated the ecological effects of host niches (soil,root,stem,leaf,and pod) and genotypes on the diversity and composition of fungal communities in peas using a multi-level approach that encompassed pattern recognition (β-diversity decomposition),mechanism validation (neutral community model testing),and dynamic tracking methods (migration pathway source-tracking).The results revealed that the dominant fungal phyla across niches and genotypes were Ascomycota,Basidiomycota,and Mortierellomycota,and the community structures of the soil–plant continuum were primarily determined by the pea niches rather than genotypes.β-diversity decomposition was largely attributed to species replacement rather than richness differences,indicating strong niche specificity and microbial replacement across microhabitats.Neutral model analysis revealed that stochastic processes influenced genotypeassociated communities,while deterministic processes played a dominant role in niche-based community assembly.Source-tracking analysis identified niche-to-niche fungal migration,with Erysiphe,Fusarium,Cephaliophora,Ascobolus,Alternaria,and Aspergillus as the key genera.Migration rates from exogenous to endogenous niches were low (1.3–61.5%),whereas those within exogenous (64.4–83.7%) or endogenous (73.9–96.4%) compartments were much higher,suggesting that the pea epidermis acts as a selective barrier that filters and enriches microbial communities prior to internal colonization.This study provides comprehensive insights into the mechanisms of host filtering,enrichment and microbial sourcing,which increases our understanding of the assembly rules of the pea-associated fungal microbiome.展开更多
Background Eating speed is a key eating behavior trait that influences energy intake and fat deposition,yet its regulation by host genetics and gut microbiota remains poorly understood in birds.Results We systematical...Background Eating speed is a key eating behavior trait that influences energy intake and fat deposition,yet its regulation by host genetics and gut microbiota remains poorly understood in birds.Results We systematically investigated the interplay among host genetics,gut microbiota,eating speed,and fat deposition in chickens.Phenotypic analyses revealed a positive association between eating speed and abdominal fat,and Mendelian randomization(MR)analysis identified a bidirectional feedback loop in which fat deposition promotes faster eating,which in turn exacerbates fat accumulation.Microbiome and MR analyses highlighted the ileal genus Bradyrhizobium as a causal regulator of both eating speed and fat deposition,with higher abundance reducing abdominal fat,triglyceride levels,and inflammatory markers.Microbiome genome-wide association studies(mGWAS)further identified host genetic variants and candidate genes,including convergent signals at RECK,influencing Bradyrhizobium abundance.Mediation analyses indicated that Bradyrhizobium modulates eating speed partially through its effects on abdominal fat,emphasizing a host-microbe-behavior feedback axis.Conclusions Our findings reveal a complex interplay among host genetics,gut microbes,and eating behavior,providing mechanistic insights and potential targets for precision interventions to optimize growth and metabolic health in poultry.展开更多
As global demand for milk and meat increases,young ruminants need rapid gut development and sufficient mucosal immunity immediately after birth.However,their growing intestines face oxidative and microbial challenges ...As global demand for milk and meat increases,young ruminants need rapid gut development and sufficient mucosal immunity immediately after birth.However,their growing intestines face oxidative and microbial challenges that can harm long-term performance.This review systematically summarizes recent advances in how host genetics,early nutrition,and emerging microbiota interact to influence intestinal development and mucosal immunity under standard rearing conditions.We explore how the host regulates the gut microbiota,the microbiota's role in maintaining gut integrity,barrier function,development,intestinal cell health,mucosal immunity,and how diet modulates gut microbiota composition in young ruminants.Microbial signals promote increased villus length and better epithelial functions.Conversely,dysbiosis delays gut closure,weakens barrier integrity,and skews immunity toward proinflammatory responses.Feeding strategies such as colostrum timing,milk replacers,and the addition of starter fiber and probiotics can alter microbial communities within days.Nonetheless,challenges remain in standardizing neonatal feeding practices,identifying microbe metabolite indicators of gut health,and integrating precision feeding technologies.By mapping the three-way interaction among host,microbiota,and diet,this review offers a blueprint for neonatal ruminant feeding that enhances both animal welfare and the productivity of future ruminant systems.This review also provides a novel mechanistic integration of host genetics,gut microbiota succession,and dietary interventions in young ruminants,filling the gap of fragmented multi-omics analyses in existing literature and offering targeted insights for optimizing gastrointestinal development and production efficiency.展开更多
Background Rumen microbiota drive fermentation and contribute to variation in feed efficiency among ruminants,yet the underlying host–microbe mechanisms remain poorly understood.This study explores how rumen microbes...Background Rumen microbiota drive fermentation and contribute to variation in feed efficiency among ruminants,yet the underlying host–microbe mechanisms remain poorly understood.This study explores how rumen microbes shape feed conversion efficiency(FCR)through integrated interactions with multiple host organs.Results We applied a multi-omics strategy—combining rumen metagenomics and host multi-organ transcriptomics—in Hu sheep with divergent FCR.From a uniform cohort of 150 weaned male Hu lambs,13 low-FCR(LFCR)and 13 high-FCR(HFCR)individuals were selected for integrated analyses.LFCR sheep exhibited greater growth performance and higher ruminal propionate concentrations compared with HFCR animals.The ruminal microbiomes were enriched in Saccharofermentans and Succinivibrionaceae_UBA2804,and showed functional convergence on amino acid biosynthesis,central carbon metabolism,and propionate-oriented fermentation in LFCR sheep.Carbohydrateactive enzyme profiles indicated that LFCR animals favored fiber-and starch-associated modules(GH126,CBM27,EPS-GT),whereas HFCR animals were enriched in host-glycan and uronic acid–degrading families(CE14,GH89,PL15).Hydrogen metabolism highlighted a clear dichotomy:LFCR animals redirected H2 toward propionate and sulfate reduction,while HFCR animals retained greater butyrate-producing and methanogenic capacity.Transcriptomic profiling across rumen epithelium,liver,and muscle identified tissue-specific regulatory modules.Only the liver showed strong enrichment of carbohydrate metabolism,with a complete glycogen turnover and glucose export system(GYS2,PYGL,PGM2,G6PC1)and pathways linking microbial short-chain fatty acids to gluconeogenesis.In contrast,muscle efficiency modules were dominated by contractile and cytoskeletal genes(e.g.,MYL2,TNNC1,TPM3),reflecting optimized energy expenditure rather than substrate metabolism.No efficiency-associated modules were detected in the rumen epithelium,consistent with its role in propionate absorption rather than metabolism.Conclusions The rumen microbiota of LFCR sheep possess highly efficient capacities for volatile fatty acid and amino acid synthesis,thereby enhancing energy utilization at its source.The resulting propionate further promotes hepatic gluconeogenesis,directly supplying energy for muscle cell growth and ultimately improving FCR.Thus,co-metabolism between rumen microbiota and the liver provides energy for muscle cell growth and is a key determinant of improved feed efficiency.展开更多
The antioxidant activity of selenium-containing soybean peptides(SePPs)has been previously demonstrated,despite their limited absorption in the small intestine.This study investigates the antioxidant mechanism of a se...The antioxidant activity of selenium-containing soybean peptides(SePPs)has been previously demonstrated,despite their limited absorption in the small intestine.This study investigates the antioxidant mechanism of a selenium-containing tetrapeptide,Ser-Phe-Gln-SeM(SFQSeM),identified from SePPs,with particular emphasis on its interaction with the intestinal microbiota and its role in modulating host antioxidant defenses.The effects of SFQSeM were evaluated in a D-galactose-induced oxidative stress model and an antibiotictreated mouse model.SFQSeM supplementation significantly reduced the oxidative stress in D-galactosetreated mice.It also promoted the growth of beneficial bacteria and increased the levels of acetate,butyrate and lactate in the intestine(P<0.05).In the antibiotic-treated mouse model,depletion of the intestinal microbiota significantly reduced hepatic glutathione peroxidase(GSH-Px)activity(26.6%)and glutathione peroxidase 1(GPx-1)expression(48.77%)compared to normal mice supplemented with SFQSeM(P<0.05).In contrast to Na2SeO3and selenomethionine,SFQSeM effectively restored the diversity of the intestinal microbiota disrupted by antibiotics.Lactobacillus,Lachnospiraceae_NK4A136_group,and Muribaculaceae were identified as predominant bacteria in the SFQSeM group,and were strongly associated with increased hepatic GSH-Px activity and GPx-1 mRNA expression(P<0.05).In conclusion,intestinal microbiota enhances the antioxidant efficacy of SFQSeM by modulating microbial composition,producing active metabolites,and converting SFQSeM into a bioactive form of selenium.展开更多
Despite their high theoretical capacity and energy density,lithiumsulfur(Li–S)batteries still face challenges such as soluble lithium polysulfides(LiPSs)shuttling and sluggish redox kinetics.In this work,we used a no...Despite their high theoretical capacity and energy density,lithiumsulfur(Li–S)batteries still face challenges such as soluble lithium polysulfides(LiPSs)shuttling and sluggish redox kinetics.In this work,we used a novel MoS2-Mo2C heterostructure anchored on a carbon sponge(CS)as a Li2S host to solve these problems.A simple hydrothermal process following carbothermal reduction was used to construct the MoS2-Mo2C heterostructure,enabling control of the phases and integration of MoS2 and Mo2C.Structural characterization confirmed the coherent interface of the heterostructure with a precise orientation relationship between the two phases and their uniform distribution.An evaluation of the adsorption and catalytic performance of the material showed that it has an exceptional LiPSs adsorption capacity with faster conversion from Li2S4 to Li2S2.Density functional theory calculations further confirmed these results.As a result,the cathode had a high initial discharge capacity of 693 mAh g−1 at 0.2 C and achieved stable cycling at 2 C for 500 cycles with a low decay rate of 0.107%per cycle.The heterostructure design,coupled with the macroporous CS framework,effectively prevented the shuttling and increased sulfur utilization,offering a promising way to produce practical high-energydensity Li–S batteries.展开更多
Single-component solution-processed organic light-emitting diodes(OLEDs)that simultaneously achieve high luminance,high efficiency,and low efficiency roll-off represent a significant challenge.Herein,we report a serie...Single-component solution-processed organic light-emitting diodes(OLEDs)that simultaneously achieve high luminance,high efficiency,and low efficiency roll-off represent a significant challenge.Herein,we report a series of thermally activated delayed fluorescence(TADF)dendrimers(m-CzBr,m-CzPhCz,m-CzCzPh and m-CzTPA)featuring a 4CzIPN emissive core tethered to diverse peripheral host units via flexible alkoxy linkers.The localized LUMO on the 4CzIPN core ensures efficient electron transport,while systematic peripheral host modulation precisely tunes photophysical properties,HOMO levels,and charge transport properties.This molecular design leads to a dramatic improvement in device performance,with external quantum efficiency(EQE)rising from 0.76%(m-CzTPA)to 26.5%(m-CzPhCz)and the maximum luminance(Lmax)increasing from 4407 to 59812 cd m-2.The optimized dendrimer,m-CzPhCz,integrates a high photoluminescence quantum yield,satisfactory charge-transport capability,and highly balanced bipolar carrier transport.These synergistic characteristics facilitate the realization of solution-processed,non-doped TADF-OLEDs that exhibit high external quantum efficiency,together with record-breaking luminance and the smallest efficiency roll-off under high brightness.Impressively,the device achieves unprecedented EQE retention of 25.4%at 5000 cd m-2 and 24%at 10000 cd m-2.展开更多
Luminescent metal-organic frameworks(MOFs)have garnered significant attention due to their structural tunability and potential applications in solid-state lighting,bioimaging,sensing,anticounterfeiting,and other field...Luminescent metal-organic frameworks(MOFs)have garnered significant attention due to their structural tunability and potential applications in solid-state lighting,bioimaging,sensing,anticounterfeiting,and other fields.Nevertheless,due to the tendency of1,4-benzenedicarboxylic acid(BDC)to rotate within the framework,MOFs composed of it exhibit significant non-radiative energy dissipation and thus impair the emissive properties.In this study,efficient luminescence of MIL-140A nanocrystals(NCs)with BDC rotors as ligands is achieved by pressure treatment strategy.Pressure treatment effectively modulates the pore structure of the framework,enhancing the interactions between the N,N-dimethylformamide guest molecules and the BDC ligands.The enhanced host-guest interaction contributes to the structural rigidity of the MOF,thereby suppressing the rotation-induced excited-state energy loss.As a result,the pressure-treated MIL-140A NCs displayed bright blue-light emission,with the photoluminescence quantum yield increasing from an initial 6.8%to 69.2%.This study developed an effective strategy to improve the luminescence performance of rotor ligand MOFs,offers a new avenue for the rational design and synthesis of MOFs with superior luminescent properties.展开更多
Discrete 2:2 host–guest complexes provide a well-defined platform for correlating supramolecular structure with emergent photophysical behavior.Althoughγ-cyclodextrin(γ-CD)is widely used in aqueous host–guest chem...Discrete 2:2 host–guest complexes provide a well-defined platform for correlating supramolecular structure with emergent photophysical behavior.Althoughγ-cyclodextrin(γ-CD)is widely used in aqueous host–guest chemistry,structurally well-defined 2:2 complexes and their formation mechanisms remain poorly understood.Here we report aγ-CD-mediated 2:2 host–guest complex formed with 1,3,6,8-tetrakis(4-carboxyphenyl)pyrene tetrasodium salt(TCP)and systematically elucidate its structural,mechanistic,and photophysical characteristics.Combined1H NMR,2D NMR,and DOSY analyses resolve the 2:2 architecture,while thermodynamic and kinetic studies reveal a multistep complexation network involving 1:1,1:2,and 2:2 species,with dimerization providing the dominant thermodynamic driving force.The resulting 2:2 complex exhibits enhanced fluorescence emission and pronounced chiroptical responses,including circular dichroism and circularly polarized luminescence,arising from supramolecular chirality induced by the chiralγ-CD cavities.Importantly,analogousγ-CD-mediated 2:2 complexation and associated photophysical features are also observed for a tetraphenylethylene-based guest,indicating that this binding mode is not limited to a single chromophoric scaffold.This study clarifies how 2:2 host–guest complexes can form inγ-CD systems and provides mechanistic insight into the emergence of chiral photophysical properties in such complexes.展开更多
Short-wavelength infrared(SWIR)organic light-emitting diodes(OLEDs)are highly attractive for applications in night vision,bio-imaging,and optical communication,yet achieving efficient emission beyond 900 nm remains ch...Short-wavelength infrared(SWIR)organic light-emitting diodes(OLEDs)are highly attractive for applications in night vision,bio-imaging,and optical communication,yet achieving efficient emission beyond 900 nm remains challenging due to severe non-radiative losses and limited exciton utilization.Here,we introduce a phosphorescent-host-based exciton management strategy,in which phosphorescent materials function as hosts rather than conventional sensitizers.By simultaneously harvesting singlet and triplet excitons,this approach enables highly efficient SWIR OLEDs with an emission peak at 1000 nm.The resulting devices deliver a record external quantum efficiency(EQE)exceeding 0.22%and a radiance of 1805 mW sr−1 m−2,representing record performance for SWIR OLEDs.Photophysical studies reveal that host-mediated exciton management and triplet energy confinement are critical to suppressing energy-loss pathways.This work establishes a general host-engineering strategy for extending OLED emission into the SWIR region.展开更多
BACKGROUND Aspergillus sydowii(A.sydowii)is a ubiquitous saprophytic mold that is only rarely implicated in human disease.Pulmonary infection due to A.sydowii is exceedingly uncommon,particularly in immunocompetent in...BACKGROUND Aspergillus sydowii(A.sydowii)is a ubiquitous saprophytic mold that is only rarely implicated in human disease.Pulmonary infection due to A.sydowii is exceedingly uncommon,particularly in immunocompetent individuals.With increasing environmental exposure and advances in fungal diagnostic techniques,rare Aspergillus species are increasingly being recognized as causative agents of respiratory infections.CASE SUMMARY A 25-year-old immunocompetent female healthcare worker from northwestern India presented with a two-week history of persistent cough,dyspnea,and sputum production.Chest computed tomography showed focal peribronchial thickening with nodular opacities in the left lower lobe.Sputum microscopy demonstrated fungal elements,and fungal culture on Sabouraud dextrose agar yielded a mold that was identified as A.sydowii by lactophenol cotton blue mount and confirmed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.The patient was treated with oral voriconazole,resulting in marked clinical improvement.CONCLUSION This case highlights A.sydowii as a rare but important cause of pulmonary infection in immunocompetent individuals.Early recognition using advanced mycological techniques such as MALDI-TOF mass spectrometry is essential for accurate diagnosis and appropriate management.展开更多
This study was conducted from October to December 2017 in the CNRA fruit orchards in Azaguié(southern Côte d’Ivoire)in order to identify alternative host plants and refuge areas for mango fruit flies during...This study was conducted from October to December 2017 in the CNRA fruit orchards in Azaguié(southern Côte d’Ivoire)in order to identify alternative host plants and refuge areas for mango fruit flies during mango off-season.Six attractants were spread in a 3 to 4 ha orchard,resulting in the capture of 6440 flies,mainly Bactrocera dorsalis.Methyl eugenol and Torula were the most effective attractants,recording 4380 flies(average:243.3 fliesrap/week)and 1484 flies(247.3 fliesrap/week),respectively,of which more than 97%were B.dorsalis.Residual fruits from 19 fruit tree species were collected and incubated.Emergence was observed on only four species:Pouteria campechiana(Sapotaceae),Myrianthus arboreus(Cecropiaceae),Chrysophyllum cainito(Sapotaceae),and Annona esculenta(Annonaceae).Infestation levels varied:P.campechiana:672 larvae,545 pupae,pupation rate 85.7%;emerged species:C.punctata(81.5%)and B.dorsalis(18.5%);Myrianthus arboreus:464 larvae,423 pupae,pupation rate 91.5%;C.anonae domine(94.3%);a native parasitoid,Fopius caudatus,represented 5.7%emergence;C.cainito:33 larvae,15 pupae,pupation rate 45.5%,emergence 53.3%,exclusively B.dorsalis;A.esculenta:503 larvae,255 pupae,pupation 71.9%,emergence 48.9%,only B.dorsalis.A total of four fly species were identified(B.dorsalis,C.cosyra,C.punctata,C.anonae)as well as a parasitoid,Fopius caudatus(Figure 1).The results showed that the orchards of Azaguiéconstitute an active refuge area for Tephritidae during the inter-seasonal period,promoting the survival of B.dorsalis and the presence of secondary host plants,and revealing a potential for natural biological control that remains under-exploited.展开更多
Coevolution within the plant holobiont extends the capacity of host plants for nutrient acquisition and stress resistance.However,the role of the rhizospheric microbiota in maintaining multinutrient utilization(i.e.mu...Coevolution within the plant holobiont extends the capacity of host plants for nutrient acquisition and stress resistance.However,the role of the rhizospheric microbiota in maintaining multinutrient utilization(i.e.multinutrient traits)in the host remains to be elucidated.Multinutrient cycling index(MNC),analogous to the widely used multifunctionality index,provides a straightforward and interpretable measure of the multinutrient traits in host plants.Using tomato as a model plant,we characterized MNC(based on multiple aboveground nutrient contents)in host plants under different nitrogen andwater supply regimes and explored the associations between rhizospheric bacterial community assemblages and host plant multinutrient profiles.Rhizosphere bacterial community diversity,quantitative abundance,predicted function,and key topological features of the co-occurrence network were more sensitive to water supply than to nitrogen supply.A core bacteriome comprising 61 genera,such as Candidatus Koribacter and Streptomyces,persisted across different habitats and served as a key predictor of host plant nutrient uptake.The MNC index increased with greater diversity and higher core taxon abundance in the rhizobacterial community,while decreasing with higher average degree and graph density of rhizobacterial co-occurrence network.Multinutrient absorption by host plants was primarily regulated by community diversity and rhizobacterial network complexity under the interaction of nitrogen and water.The high biodiversity and complex species interactions of the rhizospheric bacteriome play crucial roles in host plant performance.This study supports the development of rhizosphere microbiome engineering,facilitating effectivemanipulation of the microbiome for enhanced plant benefits,which supports sustainable agricultural practices and plant health.展开更多
Composite solid electrolytes(CSEs)are promising for solid-state Li metal batteries but suffer from inferior room-temperature ionic conductivity due to sluggish ion transport and high cost due to expensive active ceram...Composite solid electrolytes(CSEs)are promising for solid-state Li metal batteries but suffer from inferior room-temperature ionic conductivity due to sluggish ion transport and high cost due to expensive active ceramic fillers.Here,a host–guest inversion engineering strategy is proposed to develop superionic CSEs using cost-effective SiO2 nanoparticles as passive ceramic hosts and poly(vinylidene fluoride-hexafluoropropylene)(PVH)microspheres as polymer guests,forming an unprecedented“polymer guest-in-ceramic host”(i.e.,PVH-in-SiO2)architecture differing from the traditional“ceramic guest-in-polymer host”.The PVH-in-SiO2 exhibits excellent Li-salt dissociation,achieving high-concentration free Li+.Owing to the low diffusion energy barriers and high diffusion coefficient,the free Li+is thermodynamically and kinetically favorable to migrate to and transport at the SiO2/PVH interfaces.Consequently,the PVH-in-SiO2 delivers an exceptional ionic conductivity of 1.32.10−3 S cm−1 at 25℃(vs.typically 10−5–10−4 S cm−1 using high-cost active ceramics),achieved under an ultralow residual solvent content of 2.9 wt%(vs.8–15 wt%in other CSEs).Additionally,PVH-in-SiO2 is electrochemically stable with Li anode and various cathodes.Therefore,the PVH-in-SiO2 demonstrates excellent high-rate cyclability in LiFePO4|Li full cells(92.9%capacity-retention at 3C after 300 cycles under 25℃)and outstanding stability with high-mass-loading LiFePO4(9.2 mg cm−1)and high-voltage NCM622(147.1 mAh g−1).Furthermore,we verify the versatility of the host–guest inversion engineering strategy by fabricating Na-ion and K-ion-based PVH-in-SiO2 CSEs with similarly excellent promotions in ionic conductivity.Our strategy offers a simple,low-cost approach to fabricating superionic CSEs for large-scale application of solid-state Li metal batteries and beyond.展开更多
Unraveling the precise mineralization age is vital to understand the geodynamic setting and ore-forming mechanism of the sediment-hosted Pb-Zn deposit;this has long been a challenge.The Sichuan-Yunnan-Guizhou(SYG)tria...Unraveling the precise mineralization age is vital to understand the geodynamic setting and ore-forming mechanism of the sediment-hosted Pb-Zn deposit;this has long been a challenge.The Sichuan-Yunnan-Guizhou(SYG)triangle in the southwestern margin of the Yangtze Block is a globally recognized carbonate-hosted Pb-Zn metallogenic province and also an essential part of the South China low-temperature metallogenic domain.This region has>30 million tons(Mt)Zn and Pb resources and shows the enrichment of dispersed metals,such as Ga,Ge,Cd,Se,and Tl.During the past 2 decades,abundant data on mineralization ages of Pb-Zn deposits within the SYG triangle have been documented based on various radioisotopic dating methods,resulting in significant progress in understanding the geodynamic background and ore formation of Pb-Zn deposits hosted in sedimentary rocks at SYG triangle.This paper provides a comprehensive summary of the geochronological results and Pb-Sr isotopic data regarding Pb-Zn deposits in the SYG triangle,which identified two distinct Pb-Zn mineralization periods influencing the dynamic processes associated with the expansion and closure of the Paleo-Tethys Ocean in the western margin of the Yangtze Block.The predominant phase of Pb-Zn mineralization at SYG triangle spanned from the Middle Triassic to Early Jurassic(226-191 Ma),which was intensely correlated with the large-scale basin fluid transport triggered by the closure of the Paleo-Tethys Ocean and Indosinian orogeny.The secondary Pb-Zn mineralization phase occurred during the Late Devonian to Late Carboniferous and was controlled by extensional structures associated with the expansion of the Paleo-Tethys Ocean.Further investigation is necessary to clarify the occurrence and potential factors involved in the Pb-Zn mineralization events during the Late Devonian to Late Carboniferous.展开更多
基金supported financially by the National Key R&D Program of China(2022YFF0802400,2021YFD1300501)the National Natural Science Foundation of China(41971276)。
摘要The emergence of avian inffllfluenza virus(AIVs)in seabird populations has intensiffiified in recent years,signaling a signiffiificant shift in host ecology and transmission dynamics.To address this,this study introduces the Terrestrial Bird-Seabird Co-occurrence Index(TSCI),a novel metric designed to assess the spatial and temporal cooccurrence between terrestrial bird and seabird AIV hosts.The TSCI demonstrates strong predictive performance(AUC=0.94),capturing over 84.10%of conffiifirmed seabirds AIV cases within global high-risk zones.Based on this,363 Mha of coastal wetlands(representing 2.44%of global land area)were identiffiified as high-risk terrestrial birds and seabirds contact interface,providing a robust tool for identifying high-risk zones of potential virus spillover at the“terrestrial birds and seabirds contact interface.”Our analysis highlights that temperate coastal regions,particularly in Europe,North America,and East Asia,exhibit high TSCI values.Wetland ecosystems serve as critical hotspots for virus spillover,emphasizing the need for habitat-speciffiific conservation and surveillance strategies.Our study offers a scalable tool to enhance targeted monitoring,guide resource allocation,and inform integrated policies for preventing zoonotic spillover from wild bird reservoirs under the One Health framework.
基金supported by the National Natural Science Foundation of China(52202038,52336003,52172239)the Natural Science Foundation of Shandong Province(ZR2022QE081)+2 种基金the Youth Innovation Technology Project of Higher School in Shandong Province(2023KJ102)the China Postdoctoral Science Foundation(2025M770023)the Taishan Scholar Project of Shandong Province(China)(tstp20250505)。
摘要Conventional metallic current collectors in lithium-sulfur(Li-S)batteries suffer from high cost,corrosion,and poor compatibility with high-sulfur-loading electrodes.Here,we develop a current collector-free allcarbon host to achieve high-performance Li-S systems.Graphene(Gr)nanosheets are in situ grown on carbon nanotubes(CNTs)via plasma-enhanced chemical vapor deposition(PECVD),forming Gr@CNTs heterojunctions that serve simultaneously as conductive frameworks and self-supporting hosts.This hierarchical architecture can effectively overcome the stacking and closure issues of each component.Thus-obtained Gr@CNTs host exhibits ultrafast polysulfide adsorption(within 5 s in 5 mmol L-1Li2S6solution)and enables uniform sulfur deposition,ensuring efficient charge transport and suppressed shuttle effect.Consequently,the all-carbon host Li-S batteries deliver a high capacity of 1609.32 mA h g-1at 0.2C and remarkable cycling stability with only 0.073%decay per cycle over 300 cycles at 5C,establishing a promising pathway toward lightweight,high-energy-density Li-S systems.
基金LiaoNing Revitalization Talents Program(XLYC2202003)National Natural Science Foundation of China(NSFC,U24B20198)+1 种基金Fundamental Research Funds for the Central Universities(DUT23LAB612)National Key Research and Development Program of China(2022YFB4101602)。
摘要For Li metal battery,Li metal anodes severely suffer from dendritic growth due to heterogeneous electrodeposition,which inhibits their development and application.While extensive studies for Li dendrite suppression empirically utilize 3D hosts to homogenize the micro-scaled electric field within the host,the inherent correlation between host structure and electric field distribution and underlying principles remains elusive,and the corresponding design of hosts to enhance the electric effects remains challenging.Here,the host microstructure-electric field correlations are established via COMSOL simulations and demonstrate the enhanced redistribution of the electric field through structural redesign of hosts.Based on a structure model,an enhanced gradient electric field host(EGHx)with a supercontinuous gradient pore architecture is fabricated with the assistance of the porogen dissolution method,which achieves a self-leveling-like Li deposition through spatially programmed charge redistribution.Through further structural optimization,the EGH2(with 2 wt%porogen)exhibits an~98%Coulombic efficiency(CE)over 350 cycles(1 mA cm-2,1 mAh cm-2).Further multidimensional testing with argon protection reveals the role of the host in modulating solid-electrolyte interphase(SEI)composition.Accordingly,the EGH2 enables stable dendrite-free Li plating/stripping behaviors for 2100 h.The assembled full cell and pouch cell also display stable cycling performance with an LFP cathode.
基金supported by the National Natural Science Foundation of China(Nos.32260253 and 32570559 to L.W.,32470513 and 32270526 to W.L.)the Talent Research Startup Foundation of Hainan Normal University(HSZK-KYQD-202606 to L.W.)。
摘要The evolution of parasitic strategies through tracking host life-history patterns represents a key adaptive trait in avian brood parasites.However,when hosts successfully exploit human-modiffiified environments—such as diverse and concealed nesting sites—the mechanisms enabling cuckoos(Cuculus spp.)to accurately locate and parasitize such nests remains unclear.The Daurian Redstart(Phoenicurus auroreus),a human-commensal secondary cavitynester,often breeds in diverse artiffiificial structures—leading to variable and concealed nest locations—making it an ideal system to study this question.Using long-term ffiifield monitoring and a nestbox attraction experiment,we investigated how Common Cuckoos(Cuculus canorus)locate and parasitize such concealed nests.Our results show no signiffiificant variation in Common Cuckoo parasitism rates across different natural nesting sites.However,nestboxes that were more exposed experienced higher parasitism rates than natural nests.Furthermore,cuckoos targeted exclusively those boxes with active host attendance,rather than boxes occupied by other species.This study provides the ffiifirst evidence of cuckoo parasitism on a human-associated host nesting indoors,underscoring the key role of host activity cues and suggesting that cuckoos,like their hosts,are also adapting to anthropogenic refuges.
基金funded by the Beijing Research Center for Respiratory Infectious Diseases Project(BJRID2025-008)the Beijing Natural Science Foundation(5242007,L222076)+1 种基金the High-level Public Health Technical Talents Project by the Beijing Municipal Commission of Health(Key discipline personnel-02-05)the Reform and Development of the Beijing Municipal Health Commission,and the Respiratory Research Project of the National Clinical Research Center for Respiratory Diseases(HXZX-202106).
摘要Human metapneumovirus(hMPV)is a prevalent respiratory virus in children with acute lower respiratory tract infections that is highly homologous with respiratory syncytial virus(RSV),the primary etiological agent of pediatric upper and lower respiratory tract infections.Although hMPV and RSV are the only human pathogens within the Pneumoviridae family and share similar clinical manifestations,the mechanisms underlying their divergent pathogenicity remain poorly understood.In this study,we performed transcriptomic analysis on clinical respiratory samples collected between 2017 and 2019 from 61 children:including hMPV-infected,RSV-infected and healthy controls.This analysis revealed a shared upregulation of antiviral response pathways,including neutrophil activation and signaling mediated by interferons and interleukins.Conversely,cilium organization and assembly pathways were commonly downregulated in both infections.hMPV infection uniquely upregulated pathways associated with extracellular component activity,ion channel complexes,and neuroactive ligand‒receptor interactions.In contrast,pathways related to membrane rafts and membrane microdomains were uniquely downregulated in hMPV-infected patients.Analysis of differentially expressed immune-related and interferon-stimulated genes revealed significant hMPV-specific increases in EGF and FCGR1A,alongside decreased EPAS1 expression.The genes that were uniquely upregulated during hMPV infection were enriched in cytokine production regulation,cytokinecytokine receptor interactions,and PI3K/AKT signaling,whereas those that were uniquely downregulated involved the viral entry and endocytic vesicle pathways.Both hMPV infection and RSV infection significantly increased the proportions of M1 macrophages and neutrophils but decreased the proportions of M0 and M2 macrophages.Notably,hMPV infection resulted in a significant increase in monocytes and activated NK cells coupled with a decrease in resting memory CD4+T cells,compared with RSV infection.The results also revealed a significantly greater relative abundance of Prevotella salivae in the hMPV infection group,whereas Streptococcus salivarius and Streptococcus mitis were enriched in the RSV group.These distinct immune and microbial signatures provide novel insights into the pathogenesis of pediatric hMPV and RSV infections.
基金financial y supported by the National Key Research and Development Program of China (2023YFD1900902)the Joint Funds of the Zhejiang Provincial Natural Science Foundation of China (LLSSZ24C030001)+1 种基金the Earmarked Fund for China Agriculture Research System (CARS-08-G-09)sponsored by the K.C.Wong Magna Fund of Ningbo University,China。
摘要Fungi play crucial roles in nutrient acquisition,plant growth promotion,and the enhancement of resistance to both abiotic and biotic stresses.However,studies on the fungal communities associated with peas (Pisum sativum L.) remain limited.In this study,we systematically investigated the ecological effects of host niches (soil,root,stem,leaf,and pod) and genotypes on the diversity and composition of fungal communities in peas using a multi-level approach that encompassed pattern recognition (β-diversity decomposition),mechanism validation (neutral community model testing),and dynamic tracking methods (migration pathway source-tracking).The results revealed that the dominant fungal phyla across niches and genotypes were Ascomycota,Basidiomycota,and Mortierellomycota,and the community structures of the soil–plant continuum were primarily determined by the pea niches rather than genotypes.β-diversity decomposition was largely attributed to species replacement rather than richness differences,indicating strong niche specificity and microbial replacement across microhabitats.Neutral model analysis revealed that stochastic processes influenced genotypeassociated communities,while deterministic processes played a dominant role in niche-based community assembly.Source-tracking analysis identified niche-to-niche fungal migration,with Erysiphe,Fusarium,Cephaliophora,Ascobolus,Alternaria,and Aspergillus as the key genera.Migration rates from exogenous to endogenous niches were low (1.3–61.5%),whereas those within exogenous (64.4–83.7%) or endogenous (73.9–96.4%) compartments were much higher,suggesting that the pea epidermis acts as a selective barrier that filters and enriches microbial communities prior to internal colonization.This study provides comprehensive insights into the mechanisms of host filtering,enrichment and microbial sourcing,which increases our understanding of the assembly rules of the pea-associated fungal microbiome.
基金supported by Chinese Universities Scientific Fund(2025TC121)Hainan Provincial Natural Science Foundation of China(325RC806)the China Agricultural University Sanya Research Institute"Young Research Fellow"Start-up Funding Project(SYND-QDJF-04)。
摘要Background Eating speed is a key eating behavior trait that influences energy intake and fat deposition,yet its regulation by host genetics and gut microbiota remains poorly understood in birds.Results We systematically investigated the interplay among host genetics,gut microbiota,eating speed,and fat deposition in chickens.Phenotypic analyses revealed a positive association between eating speed and abdominal fat,and Mendelian randomization(MR)analysis identified a bidirectional feedback loop in which fat deposition promotes faster eating,which in turn exacerbates fat accumulation.Microbiome and MR analyses highlighted the ileal genus Bradyrhizobium as a causal regulator of both eating speed and fat deposition,with higher abundance reducing abdominal fat,triglyceride levels,and inflammatory markers.Microbiome genome-wide association studies(mGWAS)further identified host genetic variants and candidate genes,including convergent signals at RECK,influencing Bradyrhizobium abundance.Mediation analyses indicated that Bradyrhizobium modulates eating speed partially through its effects on abdominal fat,emphasizing a host-microbe-behavior feedback axis.Conclusions Our findings reveal a complex interplay among host genetics,gut microbes,and eating behavior,providing mechanistic insights and potential targets for precision interventions to optimize growth and metabolic health in poultry.
基金funded by the National Key Research and Development Program of China(2022YFA1304204)Characterization and Regulation of the Gut Functional Microbiome in Large-Scale Farmed Animals。
摘要As global demand for milk and meat increases,young ruminants need rapid gut development and sufficient mucosal immunity immediately after birth.However,their growing intestines face oxidative and microbial challenges that can harm long-term performance.This review systematically summarizes recent advances in how host genetics,early nutrition,and emerging microbiota interact to influence intestinal development and mucosal immunity under standard rearing conditions.We explore how the host regulates the gut microbiota,the microbiota's role in maintaining gut integrity,barrier function,development,intestinal cell health,mucosal immunity,and how diet modulates gut microbiota composition in young ruminants.Microbial signals promote increased villus length and better epithelial functions.Conversely,dysbiosis delays gut closure,weakens barrier integrity,and skews immunity toward proinflammatory responses.Feeding strategies such as colostrum timing,milk replacers,and the addition of starter fiber and probiotics can alter microbial communities within days.Nonetheless,challenges remain in standardizing neonatal feeding practices,identifying microbe metabolite indicators of gut health,and integrating precision feeding technologies.By mapping the three-way interaction among host,microbiota,and diet,this review offers a blueprint for neonatal ruminant feeding that enhances both animal welfare and the productivity of future ruminant systems.This review also provides a novel mechanistic integration of host genetics,gut microbiota succession,and dietary interventions in young ruminants,filling the gap of fragmented multi-omics analyses in existing literature and offering targeted insights for optimizing gastrointestinal development and production efficiency.
基金supported by the National Key Research and Development Program of China(NKPs)(Grant No.2021YFF1000703)the Fundamental Research Funds for the Central Universities(KJJQ2025020)the Research Fund of Tarim University(Grant No.HS202302)。
摘要Background Rumen microbiota drive fermentation and contribute to variation in feed efficiency among ruminants,yet the underlying host–microbe mechanisms remain poorly understood.This study explores how rumen microbes shape feed conversion efficiency(FCR)through integrated interactions with multiple host organs.Results We applied a multi-omics strategy—combining rumen metagenomics and host multi-organ transcriptomics—in Hu sheep with divergent FCR.From a uniform cohort of 150 weaned male Hu lambs,13 low-FCR(LFCR)and 13 high-FCR(HFCR)individuals were selected for integrated analyses.LFCR sheep exhibited greater growth performance and higher ruminal propionate concentrations compared with HFCR animals.The ruminal microbiomes were enriched in Saccharofermentans and Succinivibrionaceae_UBA2804,and showed functional convergence on amino acid biosynthesis,central carbon metabolism,and propionate-oriented fermentation in LFCR sheep.Carbohydrateactive enzyme profiles indicated that LFCR animals favored fiber-and starch-associated modules(GH126,CBM27,EPS-GT),whereas HFCR animals were enriched in host-glycan and uronic acid–degrading families(CE14,GH89,PL15).Hydrogen metabolism highlighted a clear dichotomy:LFCR animals redirected H2 toward propionate and sulfate reduction,while HFCR animals retained greater butyrate-producing and methanogenic capacity.Transcriptomic profiling across rumen epithelium,liver,and muscle identified tissue-specific regulatory modules.Only the liver showed strong enrichment of carbohydrate metabolism,with a complete glycogen turnover and glucose export system(GYS2,PYGL,PGM2,G6PC1)and pathways linking microbial short-chain fatty acids to gluconeogenesis.In contrast,muscle efficiency modules were dominated by contractile and cytoskeletal genes(e.g.,MYL2,TNNC1,TPM3),reflecting optimized energy expenditure rather than substrate metabolism.No efficiency-associated modules were detected in the rumen epithelium,consistent with its role in propionate absorption rather than metabolism.Conclusions The rumen microbiota of LFCR sheep possess highly efficient capacities for volatile fatty acid and amino acid synthesis,thereby enhancing energy utilization at its source.The resulting propionate further promotes hepatic gluconeogenesis,directly supplying energy for muscle cell growth and ultimately improving FCR.Thus,co-metabolism between rumen microbiota and the liver provides energy for muscle cell growth and is a key determinant of improved feed efficiency.
基金Financial support from the National Natural Science Foundation of China(32502106)One health Interdisciplinary Research Project,Institute of One Health Science,Ningbo University(NBUOH202502)the Ningbo Top Talent Project(215-432094250).
摘要The antioxidant activity of selenium-containing soybean peptides(SePPs)has been previously demonstrated,despite their limited absorption in the small intestine.This study investigates the antioxidant mechanism of a selenium-containing tetrapeptide,Ser-Phe-Gln-SeM(SFQSeM),identified from SePPs,with particular emphasis on its interaction with the intestinal microbiota and its role in modulating host antioxidant defenses.The effects of SFQSeM were evaluated in a D-galactose-induced oxidative stress model and an antibiotictreated mouse model.SFQSeM supplementation significantly reduced the oxidative stress in D-galactosetreated mice.It also promoted the growth of beneficial bacteria and increased the levels of acetate,butyrate and lactate in the intestine(P<0.05).In the antibiotic-treated mouse model,depletion of the intestinal microbiota significantly reduced hepatic glutathione peroxidase(GSH-Px)activity(26.6%)and glutathione peroxidase 1(GPx-1)expression(48.77%)compared to normal mice supplemented with SFQSeM(P<0.05).In contrast to Na2SeO3and selenomethionine,SFQSeM effectively restored the diversity of the intestinal microbiota disrupted by antibiotics.Lactobacillus,Lachnospiraceae_NK4A136_group,and Muribaculaceae were identified as predominant bacteria in the SFQSeM group,and were strongly associated with increased hepatic GSH-Px activity and GPx-1 mRNA expression(P<0.05).In conclusion,intestinal microbiota enhances the antioxidant efficacy of SFQSeM by modulating microbial composition,producing active metabolites,and converting SFQSeM into a bioactive form of selenium.
摘要Despite their high theoretical capacity and energy density,lithiumsulfur(Li–S)batteries still face challenges such as soluble lithium polysulfides(LiPSs)shuttling and sluggish redox kinetics.In this work,we used a novel MoS2-Mo2C heterostructure anchored on a carbon sponge(CS)as a Li2S host to solve these problems.A simple hydrothermal process following carbothermal reduction was used to construct the MoS2-Mo2C heterostructure,enabling control of the phases and integration of MoS2 and Mo2C.Structural characterization confirmed the coherent interface of the heterostructure with a precise orientation relationship between the two phases and their uniform distribution.An evaluation of the adsorption and catalytic performance of the material showed that it has an exceptional LiPSs adsorption capacity with faster conversion from Li2S4 to Li2S2.Density functional theory calculations further confirmed these results.As a result,the cathode had a high initial discharge capacity of 693 mAh g−1 at 0.2 C and achieved stable cycling at 2 C for 500 cycles with a low decay rate of 0.107%per cycle.The heterostructure design,coupled with the macroporous CS framework,effectively prevented the shuttling and increased sulfur utilization,offering a promising way to produce practical high-energydensity Li–S batteries.
基金supported by the National Natural Science Foundation of China(T2441002,52503235,U22A6002)。
摘要Single-component solution-processed organic light-emitting diodes(OLEDs)that simultaneously achieve high luminance,high efficiency,and low efficiency roll-off represent a significant challenge.Herein,we report a series of thermally activated delayed fluorescence(TADF)dendrimers(m-CzBr,m-CzPhCz,m-CzCzPh and m-CzTPA)featuring a 4CzIPN emissive core tethered to diverse peripheral host units via flexible alkoxy linkers.The localized LUMO on the 4CzIPN core ensures efficient electron transport,while systematic peripheral host modulation precisely tunes photophysical properties,HOMO levels,and charge transport properties.This molecular design leads to a dramatic improvement in device performance,with external quantum efficiency(EQE)rising from 0.76%(m-CzTPA)to 26.5%(m-CzPhCz)and the maximum luminance(Lmax)increasing from 4407 to 59812 cd m-2.The optimized dendrimer,m-CzPhCz,integrates a high photoluminescence quantum yield,satisfactory charge-transport capability,and highly balanced bipolar carrier transport.These synergistic characteristics facilitate the realization of solution-processed,non-doped TADF-OLEDs that exhibit high external quantum efficiency,together with record-breaking luminance and the smallest efficiency roll-off under high brightness.Impressively,the device achieves unprecedented EQE retention of 25.4%at 5000 cd m-2 and 24%at 10000 cd m-2.
基金supported by the National Key R&D Program of China(Grant No.2023YFA1406200)the National Natural Science Foundation of China(No.12274177 and 12304261)the China Postdoctoral Science Foundation(No.2024M751076)。
摘要Luminescent metal-organic frameworks(MOFs)have garnered significant attention due to their structural tunability and potential applications in solid-state lighting,bioimaging,sensing,anticounterfeiting,and other fields.Nevertheless,due to the tendency of1,4-benzenedicarboxylic acid(BDC)to rotate within the framework,MOFs composed of it exhibit significant non-radiative energy dissipation and thus impair the emissive properties.In this study,efficient luminescence of MIL-140A nanocrystals(NCs)with BDC rotors as ligands is achieved by pressure treatment strategy.Pressure treatment effectively modulates the pore structure of the framework,enhancing the interactions between the N,N-dimethylformamide guest molecules and the BDC ligands.The enhanced host-guest interaction contributes to the structural rigidity of the MOF,thereby suppressing the rotation-induced excited-state energy loss.As a result,the pressure-treated MIL-140A NCs displayed bright blue-light emission,with the photoluminescence quantum yield increasing from an initial 6.8%to 69.2%.This study developed an effective strategy to improve the luminescence performance of rotor ligand MOFs,offers a new avenue for the rational design and synthesis of MOFs with superior luminescent properties.
基金Th supported by the National Key R&D Program of China(Grant No.:2021YFA1501600 for G.W.)the National Natural Science Foundation of China(Grant No.:22250004 for X.C.,Grant No.:22171103 for G.W.,Grant No.:22301010 for Y.S.)+1 种基金the Natural Science Foun-dation of Jilin Province(Grant No.:***202301002 for G.W.)the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China(Grant No.:JYB2025XDXM401).
摘要Discrete 2:2 host–guest complexes provide a well-defined platform for correlating supramolecular structure with emergent photophysical behavior.Althoughγ-cyclodextrin(γ-CD)is widely used in aqueous host–guest chemistry,structurally well-defined 2:2 complexes and their formation mechanisms remain poorly understood.Here we report aγ-CD-mediated 2:2 host–guest complex formed with 1,3,6,8-tetrakis(4-carboxyphenyl)pyrene tetrasodium salt(TCP)and systematically elucidate its structural,mechanistic,and photophysical characteristics.Combined1H NMR,2D NMR,and DOSY analyses resolve the 2:2 architecture,while thermodynamic and kinetic studies reveal a multistep complexation network involving 1:1,1:2,and 2:2 species,with dimerization providing the dominant thermodynamic driving force.The resulting 2:2 complex exhibits enhanced fluorescence emission and pronounced chiroptical responses,including circular dichroism and circularly polarized luminescence,arising from supramolecular chirality induced by the chiralγ-CD cavities.Importantly,analogousγ-CD-mediated 2:2 complexation and associated photophysical features are also observed for a tetraphenylethylene-based guest,indicating that this binding mode is not limited to a single chromophoric scaffold.This study clarifies how 2:2 host–guest complexes can form inγ-CD systems and provides mechanistic insight into the emergence of chiral photophysical properties in such complexes.
基金support from the National Natural Science Foundation of China(Grant Nos.62175171,22175124,52573209,62375193)supported by Jiangsu Key Laboratory of Nano-Optoelectronic Materials,Suzhou Key Laboratory of Functional Nano&Soft Materials,Collaborative Innovation Center of Suzhou Nano Science&Technology(Nano-CIC),the 111 Projectthe Joint International Research Laboratory of Carbon-Based Functional Materials and Devices.
摘要Short-wavelength infrared(SWIR)organic light-emitting diodes(OLEDs)are highly attractive for applications in night vision,bio-imaging,and optical communication,yet achieving efficient emission beyond 900 nm remains challenging due to severe non-radiative losses and limited exciton utilization.Here,we introduce a phosphorescent-host-based exciton management strategy,in which phosphorescent materials function as hosts rather than conventional sensitizers.By simultaneously harvesting singlet and triplet excitons,this approach enables highly efficient SWIR OLEDs with an emission peak at 1000 nm.The resulting devices deliver a record external quantum efficiency(EQE)exceeding 0.22%and a radiance of 1805 mW sr−1 m−2,representing record performance for SWIR OLEDs.Photophysical studies reveal that host-mediated exciton management and triplet energy confinement are critical to suppressing energy-loss pathways.This work establishes a general host-engineering strategy for extending OLED emission into the SWIR region.
摘要BACKGROUND Aspergillus sydowii(A.sydowii)is a ubiquitous saprophytic mold that is only rarely implicated in human disease.Pulmonary infection due to A.sydowii is exceedingly uncommon,particularly in immunocompetent individuals.With increasing environmental exposure and advances in fungal diagnostic techniques,rare Aspergillus species are increasingly being recognized as causative agents of respiratory infections.CASE SUMMARY A 25-year-old immunocompetent female healthcare worker from northwestern India presented with a two-week history of persistent cough,dyspnea,and sputum production.Chest computed tomography showed focal peribronchial thickening with nodular opacities in the left lower lobe.Sputum microscopy demonstrated fungal elements,and fungal culture on Sabouraud dextrose agar yielded a mold that was identified as A.sydowii by lactophenol cotton blue mount and confirmed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.The patient was treated with oral voriconazole,resulting in marked clinical improvement.CONCLUSION This case highlights A.sydowii as a rare but important cause of pulmonary infection in immunocompetent individuals.Early recognition using advanced mycological techniques such as MALDI-TOF mass spectrometry is essential for accurate diagnosis and appropriate management.
摘要This study was conducted from October to December 2017 in the CNRA fruit orchards in Azaguié(southern Côte d’Ivoire)in order to identify alternative host plants and refuge areas for mango fruit flies during mango off-season.Six attractants were spread in a 3 to 4 ha orchard,resulting in the capture of 6440 flies,mainly Bactrocera dorsalis.Methyl eugenol and Torula were the most effective attractants,recording 4380 flies(average:243.3 fliesrap/week)and 1484 flies(247.3 fliesrap/week),respectively,of which more than 97%were B.dorsalis.Residual fruits from 19 fruit tree species were collected and incubated.Emergence was observed on only four species:Pouteria campechiana(Sapotaceae),Myrianthus arboreus(Cecropiaceae),Chrysophyllum cainito(Sapotaceae),and Annona esculenta(Annonaceae).Infestation levels varied:P.campechiana:672 larvae,545 pupae,pupation rate 85.7%;emerged species:C.punctata(81.5%)and B.dorsalis(18.5%);Myrianthus arboreus:464 larvae,423 pupae,pupation rate 91.5%;C.anonae domine(94.3%);a native parasitoid,Fopius caudatus,represented 5.7%emergence;C.cainito:33 larvae,15 pupae,pupation rate 45.5%,emergence 53.3%,exclusively B.dorsalis;A.esculenta:503 larvae,255 pupae,pupation 71.9%,emergence 48.9%,only B.dorsalis.A total of four fly species were identified(B.dorsalis,C.cosyra,C.punctata,C.anonae)as well as a parasitoid,Fopius caudatus(Figure 1).The results showed that the orchards of Azaguiéconstitute an active refuge area for Tephritidae during the inter-seasonal period,promoting the survival of B.dorsalis and the presence of secondary host plants,and revealing a potential for natural biological control that remains under-exploited.
基金supported by the National Natural Science Foundation of China(32202468,32372808)the Basic and Applied Basic Research Foundation of Guangdong Province(2021A1515110126,2023A1515012213)+1 种基金the Shenzhen Science and Technology Program(202206193000001,20220816113416001,JCYJ20230807111217035)the Young Elite Scientists Sponsorship Program by CAST(2019QNRC001).
摘要Coevolution within the plant holobiont extends the capacity of host plants for nutrient acquisition and stress resistance.However,the role of the rhizospheric microbiota in maintaining multinutrient utilization(i.e.multinutrient traits)in the host remains to be elucidated.Multinutrient cycling index(MNC),analogous to the widely used multifunctionality index,provides a straightforward and interpretable measure of the multinutrient traits in host plants.Using tomato as a model plant,we characterized MNC(based on multiple aboveground nutrient contents)in host plants under different nitrogen andwater supply regimes and explored the associations between rhizospheric bacterial community assemblages and host plant multinutrient profiles.Rhizosphere bacterial community diversity,quantitative abundance,predicted function,and key topological features of the co-occurrence network were more sensitive to water supply than to nitrogen supply.A core bacteriome comprising 61 genera,such as Candidatus Koribacter and Streptomyces,persisted across different habitats and served as a key predictor of host plant nutrient uptake.The MNC index increased with greater diversity and higher core taxon abundance in the rhizobacterial community,while decreasing with higher average degree and graph density of rhizobacterial co-occurrence network.Multinutrient absorption by host plants was primarily regulated by community diversity and rhizobacterial network complexity under the interaction of nitrogen and water.The high biodiversity and complex species interactions of the rhizospheric bacteriome play crucial roles in host plant performance.This study supports the development of rhizosphere microbiome engineering,facilitating effectivemanipulation of the microbiome for enhanced plant benefits,which supports sustainable agricultural practices and plant health.
基金financial support from the National Natural Science Foundation of China(Nos.52250010 and 52201242)the 261 Project of MIIT,Natural Science Foundation of Jiangsu Province(No.BK20240179)the Young Elite Scientists Sponsorship Program by CAST(No.2021QNRC001).
摘要Composite solid electrolytes(CSEs)are promising for solid-state Li metal batteries but suffer from inferior room-temperature ionic conductivity due to sluggish ion transport and high cost due to expensive active ceramic fillers.Here,a host–guest inversion engineering strategy is proposed to develop superionic CSEs using cost-effective SiO2 nanoparticles as passive ceramic hosts and poly(vinylidene fluoride-hexafluoropropylene)(PVH)microspheres as polymer guests,forming an unprecedented“polymer guest-in-ceramic host”(i.e.,PVH-in-SiO2)architecture differing from the traditional“ceramic guest-in-polymer host”.The PVH-in-SiO2 exhibits excellent Li-salt dissociation,achieving high-concentration free Li+.Owing to the low diffusion energy barriers and high diffusion coefficient,the free Li+is thermodynamically and kinetically favorable to migrate to and transport at the SiO2/PVH interfaces.Consequently,the PVH-in-SiO2 delivers an exceptional ionic conductivity of 1.32.10−3 S cm−1 at 25℃(vs.typically 10−5–10−4 S cm−1 using high-cost active ceramics),achieved under an ultralow residual solvent content of 2.9 wt%(vs.8–15 wt%in other CSEs).Additionally,PVH-in-SiO2 is electrochemically stable with Li anode and various cathodes.Therefore,the PVH-in-SiO2 demonstrates excellent high-rate cyclability in LiFePO4|Li full cells(92.9%capacity-retention at 3C after 300 cycles under 25℃)and outstanding stability with high-mass-loading LiFePO4(9.2 mg cm−1)and high-voltage NCM622(147.1 mAh g−1).Furthermore,we verify the versatility of the host–guest inversion engineering strategy by fabricating Na-ion and K-ion-based PVH-in-SiO2 CSEs with similarly excellent promotions in ionic conductivity.Our strategy offers a simple,low-cost approach to fabricating superionic CSEs for large-scale application of solid-state Li metal batteries and beyond.
基金supported by the National Natural Science Foundation of China(92162218,42302101,42202099)the Guizhou Provincial Natural Science Foundation(ZK[2023]477)。
摘要Unraveling the precise mineralization age is vital to understand the geodynamic setting and ore-forming mechanism of the sediment-hosted Pb-Zn deposit;this has long been a challenge.The Sichuan-Yunnan-Guizhou(SYG)triangle in the southwestern margin of the Yangtze Block is a globally recognized carbonate-hosted Pb-Zn metallogenic province and also an essential part of the South China low-temperature metallogenic domain.This region has>30 million tons(Mt)Zn and Pb resources and shows the enrichment of dispersed metals,such as Ga,Ge,Cd,Se,and Tl.During the past 2 decades,abundant data on mineralization ages of Pb-Zn deposits within the SYG triangle have been documented based on various radioisotopic dating methods,resulting in significant progress in understanding the geodynamic background and ore formation of Pb-Zn deposits hosted in sedimentary rocks at SYG triangle.This paper provides a comprehensive summary of the geochronological results and Pb-Sr isotopic data regarding Pb-Zn deposits in the SYG triangle,which identified two distinct Pb-Zn mineralization periods influencing the dynamic processes associated with the expansion and closure of the Paleo-Tethys Ocean in the western margin of the Yangtze Block.The predominant phase of Pb-Zn mineralization at SYG triangle spanned from the Middle Triassic to Early Jurassic(226-191 Ma),which was intensely correlated with the large-scale basin fluid transport triggered by the closure of the Paleo-Tethys Ocean and Indosinian orogeny.The secondary Pb-Zn mineralization phase occurred during the Late Devonian to Late Carboniferous and was controlled by extensional structures associated with the expansion of the Paleo-Tethys Ocean.Further investigation is necessary to clarify the occurrence and potential factors involved in the Pb-Zn mineralization events during the Late Devonian to Late Carboniferous.