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Effects of Probiotics on Breeding Environment and Intestinal Microorganisms of Livestock and Poultry 认领 引用
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作者 Pan Huiqing Zeng Yan +3 位作者 Zhang Yanda Shi Shaohua Yang Rongping Zhao Qi 《Animal Husbandry and Feed Science》 CAS 2022年第1期50-53,共4页
[Objectives] The paper was to study the effects of probiotics on breeding environment of livestock and poultry and intestinal microorgan-isms of breeding animals. [Method] Chicken houses and hog houses were selected a... [Objectives] The paper was to study the effects of probiotics on breeding environment of livestock and poultry and intestinal microorgan-isms of breeding animals. [Method] Chicken houses and hog houses were selected as the research objects. The breeding house supplemented with basal diet was used as the control group;the breeding house sprayed with probiotics product 1 was experimental group 1(exogenous treatment);the basal diet mixed with probiotics product 2 and drinking water mixed with product 3 was experimental group 2(endogenous treatment);and the com-bination of the two experimental groups was experimental group 3. [Results] Experimental groups 1 and 2 reduced the concentration of ammonia in hog houses and chicken houses, and the effect of experimental group 2 was better than that of experimental group 1. Experimental group 3 had the best effect, which significantly reduced the ammonia concentration in hog houses and chicken houses by 28.67% and 34.09%, respectively, and the average ammonia concentration outside the house within the range of 100-300 m was less than 2 mg/m3. Moreover, it significantly increased the number of intestinal lactobacillus and reduced the number of Escherichia coli. [Conclusions] Probiotics can effectively reduce the ammonia concentration in livestock and poultry breeding environment, and improve the intestinal microbial structure of breeding animals. The technology of spraying exogenous probiotics combined with the use of content-derived probiotics has great potential for popularization and application. 展开更多
关键词 Probiotics Livestock and poultry Breeding environment Intestinal microorganisms
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Lactobacillus plantarum and Lactobacillus brevis alleviate enterotoxigenic Escherichia coli-induced intestinal inflammation and stabilize intestinal microorganisms and serum metabolites in piglets 认领 引用 被引量:5
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作者 Xuebing Han Rong Gao +3 位作者 Sujuan Ding Hao Yao Jun Fang Gang Liu 《Animal Nutrition》 SCIE CAS CSCD 2025年第3期165-178,共14页
Enterotoxigenic Escherichia coli(ETEC)is a major pathogen causing diarrhea in weaned piglets,and oral administration of probiotics has become an important strategy for preventing and treating ETEC-induced diarrhea.The... Enterotoxigenic Escherichia coli(ETEC)is a major pathogen causing diarrhea in weaned piglets,and oral administration of probiotics has become an important strategy for preventing and treating ETEC-induced diarrhea.The aim of this study was to investigate the protective effect of two probiotics,Lactobacillus plantarum and Lactobacillus brevis,on ETEC-induced injury in piglets.Twenty-four piglets were randomly divided into control(CON)group(fed with a basal diet and treated with sterile saline),ETEC group(fed with the basal diet and treated with ETEC),LP-ETEC group(fed with the basal diet and treated with ETEC and L.plantarum)and LB-ETEC group(fed with the basal diet and treated with ETEC and L.brevis),with 6 piglets in each group.The experiment lasted for 21 days.The results indicated that both probiotics were able to inhibit the ETEC-induced reduction in daily weight gain of piglets and prevent the damage to jejunum.L.brevis significantly increased daily weight gain(P=0.012),while L.plantarum showed a similar trend(P=0.063).Serum metabolomic analysis showed that both probiotics significantly increased some beneficial metabolites including phosphatidylethanolamine,monoacylglyceride,cholic acid and rhodoxanthin(P<0.05).Transcriptome sequencing indicated that L.plantarum and L.brevis may alleviate piglet diarrhea by regulating genes including LBH and RNASE1.According to 16s rRNA sequencing,both probiotics were able to maintain the normal microbial community of the gut.In summary,L.plantarum and L.brevis can protect piglets from ETEC-induced damage and promote healthy growth of piglets by regulating metabolites and gene expression. 展开更多
关键词 Lactobacillus plantarum Lactobacillus brevis Enterotoxigenic Escherichia coli Metabolite Intestinal microorganism Transcriptome
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Trace metal elements: a bridge between host and intestinal microorganisms 认领 引用 被引量:20
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作者 Yong Ma Yanquan Fei +3 位作者 Sujuan Ding Hongmei Jiang Jun Fang Gang Liu 《Science China(Life Sciences)》 SCIE CAS CSCD 2023年第9期1976-1993,共18页
Trace metal elements, such as iron, copper, manganese, and zinc, are essential nutrients for biological processes. Although their intake demand is low, they play a crucial role in cell homeostasis as the cofactors of ... Trace metal elements, such as iron, copper, manganese, and zinc, are essential nutrients for biological processes. Although their intake demand is low, they play a crucial role in cell homeostasis as the cofactors of various enzymes. Symbiotic intestinal microorganisms compete with their host for the use of trace metal elements. Moreover, the metabolic processes of trace metal elements in the host and microorganisms affect the organism's health. Supplementation or the lack of trace metal elements in the host can change the intestinal microbial community structure and function. Functional changes in symbiotic microorganisms can affect the host's metabolism of trace metal elements. In this review, we discuss the absorption and transport processes of trace metal elements in the host and symbiotic microorganisms and the effects of dynamic changes in the levels of trace metal elements on the intestinal microbial community structure. We also highlight the participation of trace metal elements as enzyme cofactors in the host immune process. Our findings indicate that the host uses metal nutrition immunity or metal poisoning to resist pathogens and improve immunity. 展开更多
关键词 trace metal elements intestinal microorganisms host immunity metal metabolism
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Study on the interaction between grain polyphenols and intestinal microorganisms:A review 认领 引用 被引量:7
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作者 Yaqin Zhou Ying Zhang +2 位作者 Ming Zhou Yifei Wu Xiao Guan 《Food Bioscience》 SCIE 2023年第3期58-67,共10页
Studies have shown that grain polyphenols are mainly utilized by microorganisms in the large intestine and feedback regulate the composition of intestinal microorganisms.In addition,microorganisms in the intestine and... Studies have shown that grain polyphenols are mainly utilized by microorganisms in the large intestine and feedback regulate the composition of intestinal microorganisms.In addition,microorganisms in the intestine and the host are interdependent,and the polyphenols can coordinate their social behaviors through quorum sensing(QS)communication system.Therefore,the interaction between grain polyphenols and intestinal microorganisms were preliminarily explored in this paper,and the classification of grain polyphenols,the digestion and absorption of grain polyphenols in the gastrointestinal tract and the relationship between intestinal microorganisms and QS were summarized.It was found that grain polyphenols had a promoting effect on intestinal beneficial bacteria,and plant polyphenols can be used as a QS inhibitor to regulate the expression of virulence factors of some intestinal harmful bacteria.This study is expected to provide a theoretical basis for the study on the regulation of intestinal microorganisms by grain polyphenols through QS mechanism,in order to regulate intestinal homeostasis and promote human health. 展开更多
关键词 Grain polyphenols Intestinal microorganisms Gastrointestinal digestion Quorum sensing
Polyphenols and intestinal microorganisms:A review of their interactions and effects on human health 认领 引用 被引量:5
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作者 Zijing Li Rabia Kanwal +2 位作者 Xiqing Yue Mohan Li Aijun Xie 《Food Bioscience》 SCIE 2024年第6期373-383,共11页
This review explores the complex interactions between polyphenols and intestinal microorganisms,highlighting their significant impact on human health.Polyphenols,abundant in various plant-based foods,are renowned for ... This review explores the complex interactions between polyphenols and intestinal microorganisms,highlighting their significant impact on human health.Polyphenols,abundant in various plant-based foods,are renowned for their anti-aging,antioxidant,and lipid-lowering effects,primarily mediated through their metabolism by gut microbiota.This review investigates the absorption mechanisms of polyphenols,their metabolic pathways within the gastrointestinal tract,and the bidirectional influences between polyphenols and gut microorganisms.Key findings reveal how these interactions modulate the composition of gut microbiota and microbial metabolites,thereby influencing the gastrointestinal system,immune responses,and cardiovascular health.Additionally,the review provides a thorough analysis of recent advancements in enhancing polyphenol bioavailability,including nanoencapsulation and synergistic combinations with other bioactive compounds.By synthesizing current research,this review offers a robust theoretical framework for future studies aimed at optimizing human health through dietary polyphenols.Practical applications and future research directions are discussed,emphasizing the potential for developing innovative functional foods and therapeutic strategies that leverage polyphenolmicrobiota interactions.This work aims to advance the understanding of polyphenol-gut microbiota dynamics,thereby contributing to the fields of nutritional science and health intervention. 展开更多
关键词 Polyphenols Intestinal microorganisms Polyphenol metabolites Interactions
Regulation of dietary fiber on intestinal microorganisms and its effects on animal health 认领 引用 被引量:28
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作者 Xuebing Han Yong Ma +2 位作者 Sujuan Ding Jun Fang Gang Liu 《Animal Nutrition》 SCIE CAS CSCD 2023年第3期356-369,共14页
The animal gut harbors diverse microbes that play an essential role in the well-being of their host.Specific diets,such as those rich in dietary fiber,are vital in disease prevention and treatment because they affect ... The animal gut harbors diverse microbes that play an essential role in the well-being of their host.Specific diets,such as those rich in dietary fiber,are vital in disease prevention and treatment because they affect intestinal flora and have a positive impact on the metabolism,immunity,and intestinal function of the host.Dietary fiber can provide energy to colonic epithelial cells,regulate the structure and metabolism of intestinal flora,promote the production of intestinal mucosa,stimulate intestinal motility,improve glycemic and lipid responses,and regulate the digestion and absorption of nutrients,which is mainly attributed to short-chain fatty acids(SCFA),which is the metabolite of dietary fiber.By binding with G protein-coupled receptors(including GPR41,GPR43 and GPR109A)and inhibiting the activity of histone deacetylases,SCFA regulate appetite and glucolipid metabolism,promote the function of the intestinal barrier,alleviate oxidative stress,suppress inflammation,and maintain immune system homeostasis.This paper reviews the physicochemical properties of dietary fiber,the interaction between dietary fiber and intestinal microorganisms,the role of dietary fiber in maintaining intestinal health,and the function of SCFA,the metabolite of dietary fiber,in inhibiting inflammation.Furthermore,we consider the effects of dietary fiber on the intestinal health of pigs,the reproduction and lactation performance of sows,and the growth performance and meat quality of pigs. 展开更多
关键词 Dietary fiber Short-chain fatty acid Intestinal microorganism Inflammation Pig Lactation performance
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Phasic study of intestinal homeostasis disruption in experimental intestinal obstruction 认领 引用 被引量:11
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作者 Xiang-Yang Yu Chang-Lin Zou +3 位作者 Zhen-Li Zhou Tao Shan Dong-Hua Li Nai-Qiang Cui 《World Journal of Gastroenterology》 SCIE CAS 2014年第25期8130-8138,共9页
AIM: To investigate the phasic alteration of intestinal homeostasis in an experimental model of intestinal obstruction.
关键词 Intestinal obstruction Rabbit model Homeostasis disruption Intestinal epithelial cells Intestinal microorganisms Intestinal immune system
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Simvastatin Improves Outcomes of Endotoxin-induced Coagulopathy by Regulating Intestinal Microenvironment 认领 引用 被引量:2
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作者 Min XU Li-li LUO +4 位作者 Meng-yi DU Lu TANG Jie ZHOU Yu HU Heng MEI 《Current Medical Science》 SCIE CAS 2022年第1期26-38,共13页
Objective:The systemic inflammatory response is regarded as the major cause of endotoxin-induced coagulopathy,which is a strong predictor of mortality in patients with severe sepsis.Simvastatin plays an important role... Objective:The systemic inflammatory response is regarded as the major cause of endotoxin-induced coagulopathy,which is a strong predictor of mortality in patients with severe sepsis.Simvastatin plays an important role in reducing inflammation.In addition,the gut has long been hypothesized to be the“motor”of critical illness,driving or aggravating sepsis by the increased intestinal permeability and bacterial translocation. 展开更多
关键词 endotoxemia endotoxin-induced coagulopathy simvastatin inflammatory cytokines intestinal permeability intestinal microorganism
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Influence of Gut Microbiota and its Metabolites on Progression of Metabolic Associated Fatty Liver Disease 认领 引用 被引量:3
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作者 Yuan-Yuan Wang Hai-Lian Lin +5 位作者 Ke-Lang Wang Gen-Xiang Que Ting Cao La-Mei Zhu Xia Yang Xue-Feng Yang 《Chinese Medical Sciences Journal》 CAS CSCD 2023年第4期286-296,共11页
Metabolic associated fatty liver disease(MAFLD)has become a prevalent chronic liver disease worldwide because of lifestyle and dietary changes.Gut microbiota and its metabolites have been shown to play a critical role... Metabolic associated fatty liver disease(MAFLD)has become a prevalent chronic liver disease worldwide because of lifestyle and dietary changes.Gut microbiota and its metabolites have been shown to play a critical role in the pathogenesis of MAFLD.Understanding of the function of gut microbiota and its metabolites in MAFLD may help to elucidate pathological mechanisms,identify diagnostic markers,and develop drugs or probiotics for the treatment of MAFLD.Here we review the pathogenesis of MAFLD by gut microbiota and its metabolites and discuss the feasibility of treating MAFLD from the perspective of gut microbes. 展开更多
关键词 metabolic associated fatty liver disease intestinal microorganisms non-alcoholic fatty liver disease liver fibrosis hepatocellular carcinoma
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The Use of Restriction Fragment Length Polymorphism and Fluorescence in Situ Hybridization to Investigate Microbiota of Piglets after Feeding Oregano 认领 引用
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作者 Katrin Stelter Andreas Berk +4 位作者 Lutz Geue Stefanie Barth Petra Schlien Alexander Swidsinski Sven Danicke 《Food and Nutrition Sciences》 CAS 2014年第17期1628-1636,共9页
A total of 80 piglets (7.9 ± 1.0 kg) were used in a feeding experiment with dried oregano. The diets differed in their oregano content: 0 g, 2 g, 4 g and 8 g oregano/kg feed, corresponding to 0, 23.5, 46.9 and 93... A total of 80 piglets (7.9 ± 1.0 kg) were used in a feeding experiment with dried oregano. The diets differed in their oregano content: 0 g, 2 g, 4 g and 8 g oregano/kg feed, corresponding to 0, 23.5, 46.9 and 93.9 mg carvacrol/kg DM. After the experimental period of 5 weeks, 20 piglets of both extreme feeding groups were slaughtered: 10 animals of the control group and 10 animals of the group that received 8 g oregano/kg. Ingesta samples of jejunum, caecum and colon were collected and analyzed by FISH and PCR RFLP to compare the diversity of microbiota. The results showed no significant changes in microbiota in response to oregano. The patterns of the PCR-RFLP showed a similarity of 61.8% - 91.8% in both feeding groups. In conclusion, an effect of oregano on the in- testinal microbiota could not be shown under the methods used. 展开更多
关键词 Piglets Origanum vulgare L. Fluorescence in Situ Hybridization Restriction Fragment Length Polymorphism Intestinal Microorganisms
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Can drinking tea become an effective way to alleviate the extraintestinal manifestations of inflammatory bowel disease:A comprehensive review 认领 引用 被引量:3
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作者 Yong Lin Siling Xie +5 位作者 Lizheng Xiao Zhenyun Liu Wanping Ke Jian-an Huang Zhonghua Liu Wei Quan 《Food Bioscience》 SCIE 2024年第3期414-426,共13页
Inflammatory bowel disease(IBD)has become increasingly prevalent worldwide in the past decade,often accompanied by various parenteral manifestations,which seriously affecting the liver,bile,kidney,cardiovascular,and e... Inflammatory bowel disease(IBD)has become increasingly prevalent worldwide in the past decade,often accompanied by various parenteral manifestations,which seriously affecting the liver,bile,kidney,cardiovascular,and even brain functions.Tea contains various active ingredients,including polyphenols,and polysaccharides with good anti-inflammatory and antioxidant properties.Previous studies have shown that tea can alleviate IBD symptoms.To review the effects and mechanism of tea consumption on the extraintestinal manifestations of IBD,data were collected from PubMed,Embase,Web of Science,ScienceDirect,and China National Knowledge Infrastructure databases from initial establishment to Oct 2023.This study reviewed the pathophysiological mechanisms of inflammatory bowel disease and its extraintestinal manifestations,as well as the intervention effects of tea consumption on inflammatory bowel disease.Meanwhile,the potential effects and mechanisms of tea drinking in alleviating IBD and its extraintestinal manifestations including hepatobiliary and renal manifestations,cardiovascular diseases,and brain inflammation were explored through anti-inflammatory and antioxidant signaling pathways,and the regulation of intestinal microorganisms and metabolic pathways were also discussed.This review aims to broaden the scope of the development and application of tea consumption as potential effective approach for daily health management and alleviation of chronic diseases. 展开更多
关键词 Tea consumption Inflammatory bowel disease Extraintestinal manifestations Intestinal microorganisms Pathophysiological mechanisms
Effect of low-salinity seawater transient on antioxidant capacity,muscle quality and intestinal microorganism of crucian carp(Carassius auratus gibelio) 认领 引用 被引量:1
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作者 Yawen Hong Yunyun Pan +6 位作者 Qijian Zhu Yongyong Li Huicheng Yang Bangchu Lin Zheyun Dong Yongjiang Lou Shiqian Fu 《Food Bioscience》 SCIE 2024年第6期4310-4319,共10页
Freshwater fish are frequently disliked by consumers due to their fishy odor and loose texture.Therefore,salinity treatment before market release is crucial for improving the muscle quality of freshwater fish.In this ... Freshwater fish are frequently disliked by consumers due to their fishy odor and loose texture.Therefore,salinity treatment before market release is crucial for improving the muscle quality of freshwater fish.In this study,Carassius auratus gibelio was temporarily reared in low-salinity seawater(6 ppt)for 15 days,and changes of antioxidant levels,muscle texture,and intestinal microbial were determined.After temporary rearing in seawater,the hardness,gumminess,and chewiness of the muscle texture improved,and the relative contents of fishy and fatty odors decreased.This indicated that low-salinity treatment can enhance muscle quality and flavor while reducing fishy odor.According to microbiome research,low-salinity saltwater temporarily reduced the relative abundance of some opportunistic pathogens,such as Vibrio(from 47.61% to 0.1%)and Shewanella(from 15.20% to 5.86%)in the intestinal tract of crucian carp,and increased the relative abundance of beneficial bacteria,such as Sphingomonas(from 2.52% to 28.38%).This study can provide a reference for using low-salinity seawater for temporary rearing to enhance the quality of fish prior to marketing. 展开更多
关键词 Carassius auratus gibelio Salinity Seawater Muscle quality Intestinal microorganisms
Inhibition of anaerobic probiotics on colorectal cancer cells using intestinal microfluidic systems 认领 引用
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作者 Lin Zhou Sifeng Mao +2 位作者 Qiushi Huang Xiangwei He Jin-Ming Lin 《Science China Chemistry》 SCIE EI CAS CSCD 2018年第8期1034-1042,共9页
Intestinal flora play an important role in human's immune system. Many bacteria adhere to the wall of the testinal wall. These Intestinal flora help digestion, and also stop their disease-causing counterparts from... Intestinal flora play an important role in human's immune system. Many bacteria adhere to the wall of the testinal wall. These Intestinal flora help digestion, and also stop their disease-causing counterparts from invading. Most of the current researches focused on the interaction between cells and the construction of organs, but few researches studied on the role of microorganisms and cells. Here, we developed an in vitro living cell systems to simulate the structure, absorption, transport and pathophysiological characteristics of the human intestinal tract and the key microbial symbiosis. The co-culture of Clostridium butyricum(C.butyricum) and colon cancer cells showed a different immune effect. C. butyricum could inhibit the proliferation of HCT116 cells, cause cell cycle arrest and promote apoptosis. But it had no significant effect on Caco-2 cells. Thus, basic functional characteristics of the gut were successfully simulated in a controlled microfluidic system. This approach is suggested as a powerful method in the investigation on drug metabolism and intestinal diseases. 展开更多
关键词 microfluidics intestinal microorganisms co-culture metabolism
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