Objectives:Missed nursing care is a widespread issue in clinical practice and represents a global challenge.Reducing missed nursing care is crucial for improving care quality and implementing high-quality nursing serv...Objectives:Missed nursing care is a widespread issue in clinical practice and represents a global challenge.Reducing missed nursing care is crucial for improving care quality and implementing high-quality nursing services.This study conducted a longitudinal survey among clinical nurses to investigate the impact and underlying mechanisms of the nursing work environment,moral sensitivity,and humanistic care ability on missed nursing care,aiming to provide theoretical evidence for optimizing the work environment and enhancing nursing quality.Methods:From October 2024 to April 2025,a longitudinal survey was conducted at three time points among 989 clinical nurses using the Nursing Work Environment Scale,Missed Nursing Care Scale,Moral Sensitivity Questionnaire,and the Nurse Humanistic Care Ability Scale.A total of 902 valid responses were included in the final analysis.Structural equation modeling and mediation pathway analysis were performed using AMOS 26.0,and data analysis was conducted using SPSS 25.0.Results:The mean score of missed nursing care among clinical nurses was 43.10±15.87.The clinical nursing work environment was negatively correlated with missed nursing care(r=−0.502,P<0.01),and positively correlated with both moral sensitivity(r=0.241,P<0.01)and humanistic care ability(r=0.312,P<0.01).Moral sensitivity was positively correlated with humanistic care ability(r=0.228,P<0.01)and negatively correlated with missed nursing care(r=−0.430,P<0.01).Furthermore,humanistic care ability was negatively correlated with missed nursing care(r=−0.526,P<0.01).Moral sensitivity and humanistic care ability served as a chain mediating pathway between the nursing work environment and missed nursing care(β=−0.015,P<0.001),and the overall model demonstrated good fit indices.Conclusion:The clinical nursing work environment is a key factor influencing missed nursing care.Moral sensitivity and humanistic care ability among nurses act as a mediating mechanism linking the nursing work environment to missed nursing care.Therefore,healthcare administrators may consider strengthening nurses’moral sensitivity and humanistic care capacity as strategic entry points for developing targeted interventions to reduce missed nursing care.展开更多
Developing high-performance catalysts that possess both strong oxidation and reduction capabilities remains a big challenge.Herein,a multi-level complex heterostructure system with both heterojunction and heterophase ...Developing high-performance catalysts that possess both strong oxidation and reduction capabilities remains a big challenge.Herein,a multi-level complex heterostructure system with both heterojunction and heterophase junction(hollow core-shell CeO2@t-BiVO4/m-BiVO4)was developed.Vacancymediated active electron transfer behavior between low-valent metal elements simultaneously enhances photocatalytic oxidation and reduction properties,ultimately achieving a 4.25-fold increase in oxidation capability and a 4.56-fold increase in reduction capability.The reason that the heterostructure system is more favorable for multi-electron transfer processes is owing to the abundant oxygen vacancies(Ov)and the flexible Ce3+/Ce4+redox behavior in CeO2.Notably,the rapid interconversion of Ce3+/Ce4+can accelerate the effective transfer and efficient utilization of photogenerated electrons.Concurrently,the transfer of electrons from Ce3+to Bi3+,Ovand V4+sites enhances the separation ability of photogenerated charge carriers and effectively reduces the high recombination caused by localized electron enrichment,which is the key to the significant enhancement of both oxidation and reduction capabilities.This study is expected to provide new insights into the design of high-performance photocatalysts capable of effectively addressing the challenges of water pollution and CO2reduction.展开更多
Working memory is a fundamental aspect of brain cognitive function.Its anti-interference ability relies on the network structure and the balance between excitatory and inhibitory neurons in neural systems.Here,we disc...Working memory is a fundamental aspect of brain cognitive function.Its anti-interference ability relies on the network structure and the balance between excitatory and inhibitory neurons in neural systems.Here,we discuss the resistance of the spiking neuron-astrocyte network(SNAN)to noise interference of the input signal during working memory tasks,and we underscore that astrocytes play an essential regulatory role in synaptic plasticity.These results indicate that,compared to the SNAN and spiking neuron network(SNN),the improved SNAN incorporated 2-Arachidonoylglycerol(2-AG)modulation displays notable resistance to high noise interference.The improved SNAN shows optimal working memory performance,demonstrating a greater correlation between recalled patterns and input patterns.This may be due to the reduced connection sparsity of the neural network and decreased neural firing frequency caused by 2-AG,as well as its simultaneous impact on the secretion of glutamate.At the same time,astrocytes affecting memory maintenance generate overlapping calcium signals in multi-task working memory.In addition,astrocytes can significantly enhance working memory performance by modulating synaptic coupling under high noise interference.This study may provide insights into understanding the role of astrocytes in the neural mechanisms of working memory and information processing.展开更多
Early social isolation(SI)impairs social ability,which can be partially rescued after resocialization,but the underlying mechanisms have been rarely addressed.This study reported that adolescent SI mice resocialized w...Early social isolation(SI)impairs social ability,which can be partially rescued after resocialization,but the underlying mechanisms have been rarely addressed.This study reported that adolescent SI mice resocialized with group housing(GH)mice,but not with SI mice,showed improved social behavior performances,increased myelination in the medial prefrontal cortex(mPFC),and upregulated Egr2 expression in oligodendrocytes(OLs).Specific downregulation of OL Egr2 in GH companions or overexpression of OL Egr2 in SI peers abolished or rescued their repair effects on mPFC hypomyelination and social ability defects in SI mice,respectively.Furthermore,the improving effect of GH companions on OL Egr2 expression and myelinogenesis in the mPFC of SI mice was abolished when GH mice were treated with corticosterone.RNA-sequencing analysis showed that Egr2 enhanced myelination by inhibiting PDGFRα.Together,these results revealed that the Egr2/PDGFRαaxis mediates distinct peer effects in rescuing SIinduced hypomyelination and social ability impairment.展开更多
Mango(Mangifera indica)is a tropical,climacteric fruit with unique flavor and rich nutrition,but its postharvest shelf life is limited due to softening,rotting,and cold damage susceptibility.Recent research indicates ...Mango(Mangifera indica)is a tropical,climacteric fruit with unique flavor and rich nutrition,but its postharvest shelf life is limited due to softening,rotting,and cold damage susceptibility.Recent research indicates that storage at 12℃ can preserve mango fruit well,but the underlying preservation mechanism remains poorly understood.In this study,postharvest quality changes and antioxidant mechanism of‘Tainong No.1'mango stored at 12 and 30℃ with 90%±5%RH for 24 d were explored.The results showed that,compared with storage at 30℃,storage at 12℃ significantly maintained fruit firmness,while reducing weight loss rate and malondialdehyde(MDA)content.Better cell morphology and delayed starch degradation were found at 12℃ through microscopic analysis.Moreover,the mango fruit stored at 12℃ showed significantly enhanced activities of antioxidant enzymes,including peroxidase(POD),superoxide dismutase(SOD),phenylalanine ammonia lyase(PAL),and ascorbate peroxidase(APX).Induced expressions of enzyme genes supported the corresponding enhanced enzyme activities.Furthermore,correlation analysis demonstrated that SOD,total phenols,and flavonoids might have a greater contribution to balancing the ROS homeostasis of postharvest mangoes.These findings suggest that storage at 12℃ might maintain mango quality and prolong the storage period by regulating fruit antioxidant capacity.展开更多
Background:Maternal mental health literacy is a cognitive resource that may support preschoolers’emotional development,yet its influence on emotional regulation and the related mechanisms remains unclear.This study e...Background:Maternal mental health literacy is a cognitive resource that may support preschoolers’emotional development,yet its influence on emotional regulation and the related mechanisms remains unclear.This study examined whether maternal depressive mood and democratic parenting form a chain pathway linking maternal mental health literacy to preschoolers’emotional regulation ability.Methods:Mothers of 544 preschoolers in China’s Mainland completed an online questionnaire that assessed maternal mental health literacy,depressive mood,democratic parenting,and child emotional regulation.Structural path analysis was conducted with child age and gender controlled.Indirect effects were tested using 5000 bootstrap samples.Results:Maternal mental health literacy did not directly predict preschoolers’emotional regulation.Three indirect effects were significant.The pathway through depressive mood had an effect of 0.005,the pathway through democratic parenting had an effect of 0.004,and the chain pathway through depressive mood and democratic parenting had an effect of 0.002.All confidence intervals excluded 0.Conclusion:Maternal mental health literacy influences preschoolers’emotional regulation only through maternal depressive mood and democratic parenting,indicating that cognitive resources affect child emotional outcomes through emotional and behavioral processes rather than a direct pathway.展开更多
In response to the practical problems of insufficient cultivation of innovative thinking,weak practical application ability,and fragmented research training systems among current pharmacy undergraduates,this study con...In response to the practical problems of insufficient cultivation of innovative thinking,weak practical application ability,and fragmented research training systems among current pharmacy undergraduates,this study constructs a theoretical model of synergistic education characterized by"competitiondriven innovation,innovationdriven learning,and deep integration of competition and innovation",using disciplinary competitions and the College Student Innovation and Entrepreneurship Training Program(College Student Innovation Program)as dual core carriers.Through the coordinated integration of disciplinary competition resources,optimization of the toplevel design of the College Student Innovation Program,establishment of interdisciplinary practical platforms,and construction of a wholeprocess diversified evaluation system,the core abilities of pharmacy undergraduates including scientific research thinking,practical operation,teamwork,and innovation achievement transformation are systematically strengthened.Based on the inherent laws of cultivating innovative pharmaceutical talents and the development needs of the pharmaceutical industry,this study explores the theoretical reconstruction of educational pathways,providing a referenceable and scalable theoretical framework and implementation paradigm for the cultivation of innovative pharmaceutical talents in the new era.展开更多
Objective:This study aims to understand the medical science popularization abilities of medical students and their influencing factors,providing a reference for improving medical students’medical science popularizati...Objective:This study aims to understand the medical science popularization abilities of medical students and their influencing factors,providing a reference for improving medical students’medical science popularization capabilities.Methods:From November 2024 to January 2025,310 medical students from Tianjin,Baotou,Fuzhou,and Yinchuan were selected as the study subjects.Surveys were conducted using a general information questionnaire and an evaluation scale for medical students’medical science popularization abilities.Results:The median score for medical science popularization abilities among the 310 medical students was 172(interquartile range:159,198).Multiple linear regression analysis revealed that the students’place of origin,grade level,and whether they had experience in medical science popularization were the primary influencing factors,accounting for 10%of the total variance.Conclusion:Medical students’medical science popularization abilities are at a moderate level.School administrators need to develop targeted intervention measures based on these influencing factors to enhance medical students’medical science popularization capabilities.展开更多
Intelligent technology and digital education strategy are profoundly reshaping the teaching paradigm of application-oriented colleges and universities,and putting forward new requirements for teachers’teaching abilit...Intelligent technology and digital education strategy are profoundly reshaping the teaching paradigm of application-oriented colleges and universities,and putting forward new requirements for teachers’teaching ability.This paper systematically analyzes the three transformation trends of teaching objectives turning to ability generation,teaching scene extending to open ecology,and technology role upgrading as core empowerment,and then analyzes the multi-dimensional ability challenges faced by teachers from the four dimensions of goal design,process control,technology integration,and role transformation.The research points out that to meet these challenges,it is necessary to build integrated practice-oriented teacher development content,create a school-based support environment for collaborative innovation,and improve the teaching evaluation and incentive mechanism with clear guidance.This paper aims to provide a reference for the theoretical construction and practical improvement of teachers’ability development in application-oriented universities.展开更多
Rheumatoid arthritis(RA)patients face significant psychological challenges alongside physical symptoms,necessitating a comprehensive understanding of how psychological vulnerability and adaptation patterns evolve thro...Rheumatoid arthritis(RA)patients face significant psychological challenges alongside physical symptoms,necessitating a comprehensive understanding of how psychological vulnerability and adaptation patterns evolve throughout the disease course.This review examined 95 studies(2000-2025)from PubMed,Web of Science,and CNKI databases including longitudinal cohorts,randomized controlled trials,and mixed-methods research,to characterize the complex interplay between biological,psychological,and social factors affecting RA patients’mental health.Findings revealed three distinct vulnerability trajectories(45%persistently low,30%fluctuating improvement,25%persistently high)and four adaptation stages,with critical intervention periods occurring 3-6 months postdiagnosis and during disease flares.Multiple factors significantly influence psychological outcomes,including gender(females showing 1.8-fold increased risk),age(younger patients experiencing 42%higher vulnerability),pain intensity,inflammatory markers,and neuroendocrine dysregulation(48%showing cortisol rhythm disruption).Early psychological intervention(within 3 months of diagnosis)demonstrated robust benefits,reducing depression incidence by 42%with effects persisting 24-36 months,while different modalities showed complementary advantages:Cognitive behavioral therapy for depression(Cohen’s d=0.68),mindfulness for pain acceptance(38%improvement),and peer support for meaning reconstruction(25.6%increase).These findings underscore the importance of integrating routine psychological assessment into standard RA care,developing stage-appropriate interventions,and advancing research toward personalized biopsychosocial approaches that address the dynamic psychological dimensions of the disease.展开更多
BACKGROUND Lower extremity arteriosclerotic occlusive disease(LEAOD)is a prevalent chronic vascular condition that significantly increases the risk of lower limb dysfunction and depressive symptoms.Mindfulness-based i...BACKGROUND Lower extremity arteriosclerotic occlusive disease(LEAOD)is a prevalent chronic vascular condition that significantly increases the risk of lower limb dysfunction and depressive symptoms.Mindfulness-based interventions have demonstrated efficacy in improving mood and coping ability in patients with various chronic illnesses;however,their specific impact on the dual burden of depression and walking ability in patients with LEAOD remains unclear.AIM To explore mindfulness training impact on depression scores and walking ability in patients with LEAOD complicated with depression.METHODS From September 2023 to October 2025,176 patients with LEAOD and depression were enrolled and divided into the control(routine treatmentursing,n=93)and study(mindfulness training plus routine treatmentursing,n=83)groups.Baseline confounding factors were balanced between the groups using 1:1 propensity score matching,with 62 cases in each group.Depression scores,walking ability,self-efficacy,quality-of-life,and complications were compared between the two groups before the intervention,8 weeks after the intervention,and at 1 month follow-up.RESULTS After 8 weeks of intervention and at 1 month follow-up,the Self-Rating Depression Scale score of the intervention group were 37.21±5.32 and 30.76±4.94 points,respectively,which were significantly lower than those of the control group(44.68±5.77 and 38.94±5.13 points)(P<0.05).The pain-free walking distance in the intervention group were 243.06±13.44 m and 263.35±11.52 m,respectively,and the six-minute walk distances were 387.24±15.22 m and 426.55±13.02 m,respectively,both of which were higher than those of the control group(pain-free walking distance:224.55±11.87 m and 244.56±10.43 m;six-minute walk distances:364.45±13.34 m and 307.06±10.73 m)(P<0.05).The Chinese Self-Efficacy Exercise Scale and MOS36-item short form health survey scores of the two groups were significantly higher than those before the intervention(P<0.05).The total complication rate in the intervention group was 3.23%lower than that in the control group(14.52%)(P<0.05).CONCLUSION Mindfulness training effectively alleviated depression and enhanced walking ability,self-efficacy,and quality-oflife in patients with LEAOD concomitant with depression,suggesting a valuable supplementary rehabilitation intervention.展开更多
As outstanding talents of higher education in China,postgraduates majoring in ethnic medicine should have their career development ability cultivated.This study explores countermeasures to improve the professional abi...As outstanding talents of higher education in China,postgraduates majoring in ethnic medicine should have their career development ability cultivated.This study explores countermeasures to improve the professional ability training of ethnic medicine postgraduates,helping them establish correct career awareness and conduct reasonable career planning,so as to improve competitiveness in the increasingly severe employment situation and solve the employment difficulties of ethnic medicine postgraduates,which can make positive contributions to the medical and health undertakings of the motherland.It is highly necessary to cultivate postgraduates’professional ability and guide reasonable career planning.展开更多
Medical research and human health are deeply connected,and international medical exchanges play a important role in raising research level.This study employs bibliometric and visual analytic approaches to identify eff...Medical research and human health are deeply connected,and international medical exchanges play a important role in raising research level.This study employs bibliometric and visual analytic approaches to identify effective strategies for improving international medical collaborations.We retrieved relevant literature from the Web of Science Core Collection,including SCI-Expanded,SSCI,CPCI-S,and CPCI-SSH databases,covering the period 1992-2022.CiteSpace software was utilized to generate knowledge visualization maps.A total of 443 articles were included in the analysis.The number of publications related to international educational exchange in medicine has grown steadily over time.Keyword co-occurrence analysis identified“international educational exchange,”“higher education,”“healthcare,”and“global health”as the most prevalent terms.Remote online training has emerged as a prevalent modality for international educational exchange and cooperation.Technologies leveraging computer networks for platform-based learning have attained increasing sophistication.Future international collaboration will be characterized by openness,resource-sharing,diversity,and digitalization(intelligence).展开更多
This study aimed to evaluate the application of the problem-based learning(PBL)teaching method in emergency ultrasound training,specifically its effect on improving rapid diagnostic ability and learning outcomes.From ...This study aimed to evaluate the application of the problem-based learning(PBL)teaching method in emergency ultrasound training,specifically its effect on improving rapid diagnostic ability and learning outcomes.From May 2020 to May 2025,40 emergency ultrasound resident doctors were randomly selected and divided into a control group(n=20,receiving conventional teaching)and an observation group(n=20,receiving PBL teaching).After training,the observation group scored significantly higher than the control group in both rapid diagnostic ability for emergency ultrasound(including static image/dynamic video interpretation,standard section acquisition,rapid screening process and timeliness,quality of written diagnostic reports,and clinical decision support)and learning effect scores(learning interest,learning initiative,and self-confidence),with all differences showing statistical significance(p<0.05).In conclusion,the application of the PBL teaching method in emergency ultrasound training for resident doctors effectively enhances their rapid diagnostic ability and learning outcomes.展开更多
Objective:To explore the impact of narrative medicine writing intervention on the empathy ability and job burnout of residents undergoing standardized training in oncology(referred to as“standardized training”),and ...Objective:To explore the impact of narrative medicine writing intervention on the empathy ability and job burnout of residents undergoing standardized training in oncology(referred to as“standardized training”),and to provide empirical evidence for optimizing the standardized training system in oncology.Methods:A total of 70 trainees who received standardized training in the oncology department of our hospital from January 2024 to June 2025 were selected as the study subjects.They were divided into an observation group and a control group with 35 cases each according to the random number table method.The control group received routine standardized training in oncology,while the observation group received additional narrative medicine writing training on the basis of routine standardized training.Baseline data of the two groups were statistically analyzed,and the empathy ability and job burnout levels of the trainees in both groups were evaluated before the intervention(January 2024)and after the intervention(June 2025),respectively.Results:Before the intervention,there were no statistically significant differences in demographic characteristics such as gender,age,educational background,and rotation duration between the two groups of trainees(all P>0.05).After the intervention,the total score and scores in each dimension of the JSE-HP in the observation group were significantly higher than those in the control group,and the scores in the observation group after the intervention were significantly higher than those before the intervention(all P<0.001).After the intervention,the scores in the dimensions of emotional exhaustion and cynicism in the observation group were significantly lower than those in the control group,while the score in the dimension of reduced professional efficacy was significantly higher than that in the control group.Moreover,in the observation group,the scores in emotional exhaustion and cynicism decreased significantly after the intervention,and the score in reduced professional efficacy increased significantly(all P<0.001).After the intervention,the total score of the JSE-HP in the observation group showed a significant negative correlation with the emotional exhaustion dimension of the MBI-GS(r=-0.664,P<0.001),a significant negative correlation with the cynicism dimension(r=-0.571,P<0.001),and a significant positive correlation with the reduced professional efficacy dimension(r=0.425,P<0.001).Conclusion:Narrative medicine writing can effectively enhance the empathy ability of trainees in standardized training programs for oncology and reduce their level of job burnout,making it worthy of promotion and application in the standardized training system for oncology.展开更多
Objective:To analyze the improvement effect of early postoperative rehabilitation training on balance ability and quality of life in elderly patients with hip fracture.Methods:A total of 50 elderly patients with hip f...Objective:To analyze the improvement effect of early postoperative rehabilitation training on balance ability and quality of life in elderly patients with hip fracture.Methods:A total of 50 elderly patients with hip fracture admitted to our hospital from January 2023 to January 2024 were selected and divided into the observation group(25 cases)and the control group(25 cases)by random number table method.The control group received routine nursing,while the observation group received early rehabilitation training on the basis of routine nursing.The balance ability(Berg Balance Scale,BBS)and quality of life(SF-36)of the two groups were compared.Results:The BBS scores of the observation group at all postoperative time points were significantly higher than those of the control group(p<0.05),and the quality-of-life scores of the observation group were also significantly higher than those of the control group(p<0.05).Conclusion:Early postoperative rehabilitation training for elderly patients with hip fracture can improve their balance ability,enhance their quality of life,and reduce the incidence of postoperative complications,which is worthy of clinical promotion.展开更多
Objective:To explore the intervention effect of the bidirectional quality feedback nursing model on the quality of life and self-management ability of patients with chronic obstructive pulmonary disease(COPD).Methods:...Objective:To explore the intervention effect of the bidirectional quality feedback nursing model on the quality of life and self-management ability of patients with chronic obstructive pulmonary disease(COPD).Methods:A total of 60 COPD cases in the stable phase of the disease admitted to our hospital from January to December 2024 were included.Using a random number table method,they were divided into a control group and an observation group,with 30 cases in each group.The control group received the standard nursing protocol,while the observation group underwent a three-month bidirectional quality feedback nursing intervention in addition to the standard protocol.The quality of life and self-management ability scores of the two groups were compared before and after the intervention.Results:After the intervention,compared with the control group,the observation group showed lower scores in all dimensions of the St.George’s Respiratory Questionnaire(SGRQ)and higher scores in all domains and the total score of the Self-Care of Chronic Illness Inventory-Modified for COPD(SCMMS)(p<0.05).Conclusion:The bidirectional quality feedback nursing intervention can significantly improve the self-care level and quality of life of patients with COPD,demonstrating clinical application value.展开更多
Guided by the National Vocational College Skills Competition Teaching Ability Competition,this paper selects the“Object Detection”teaching unit and elaborates on the teaching design and practice process in detail fr...Guided by the National Vocational College Skills Competition Teaching Ability Competition,this paper selects the“Object Detection”teaching unit and elaborates on the teaching design and practice process in detail from aspects such as overall teaching design,teaching implementation process,students’learning effects,and reflection and improvement measures.By introducing real application scenarios of smart factories,it cultivates students’craftsman spirit of striving for excellence and sense of responsibility to serve the country through science and technology,providing experience and reference for transporting high-quality technical and skilled talents for the high-quality development of the artificial intelligence industry.展开更多
The low egg production of goose greatly limits the development of the industry.China possesses the most abundant goose breeds resources.In this study,genome resequencing data of swan goose(Anser cygnoides)and domestic...The low egg production of goose greatly limits the development of the industry.China possesses the most abundant goose breeds resources.In this study,genome resequencing data of swan goose(Anser cygnoides)and domesticated high and low laying goose breeds(Anser cygnoides domestiation)were used to identify key genes related to egg laying ability in geese and verify their functions.Selective sweep analyses revealed 416 genes that were specifically selected during the domestication process from swan geese to high laying geese.Furthermore,SNPs and Indels markers were used in GWAS analyses between high and low laying breed geese.The results showed that RTCB,BPIFC,SYN3,SYNE1,VIP,and ESR1 may be related to the differences in laying ability of geese.Notably,only ESR1 was identified simultaneously by GWAS and selective sweep analysis.The genotype of Indelchr3:54429172,located downstream of ESR1,was confirmed to affect the expression of ESR1 in the ovarian stroma and showed significant correlation with body weight at first egg and laying frequency of geese.CCK-8,EdU,and flow cytometry confirmed that ESR1 can promote the apoptosis of goose pre-hierarchical follicles ganulosa cells(phGCs)and inhibit their proliferation.Combined with transcriptome data,it was found ESR1 involved in the function of goose phGCs may be related to MAPK and TGF-beta signaling pathways.Overall,our study used genomic information from different goose breeds to identify an indel located in the downstream of ESR1 associated with goose laying ability.The main pathways and biological processes of ESR1 involved in the regulation of goose laying ability were identified by cell biology and transcriptomics methods.These results are helpful to further understand the laying ability characteristics of goose and improve the egg production of geese.展开更多
Radial jet drilling(RJD)technology is expected to be a technology for the efficient exploitation of geothermal resources.However,the low rock-breaking efficiency is the major obstacle hindering the development of RJD ...Radial jet drilling(RJD)technology is expected to be a technology for the efficient exploitation of geothermal resources.However,the low rock-breaking efficiency is the major obstacle hindering the development of RJD technology.The flow field characteristics and rock breaking ability of cone-straight abrasive jet,rotary abrasive jet,and straight-rotating mixed abrasive jet are analyzed by numerical simulations and experiments.Results show that the axial velocity of the cone-straight abrasive jet is high,the tangential velocity is basically zero,the radial velocity is also small,and the jet impact area is concentrated in the center.A deep hole with a diameter of only 25 mm is formed when the cone-straight abrasive jet breaks the granite.Due to the presence of the guiding impeller,the rotary abrasive jet basically has no axial velocity and has the highest tangential and radial velocity,so it can break the granite to form a hole with a diameter of about 55 mm and a central bulge.The straight-rotating mixed abrasive jet has a large axialangentialadial velocity at the same time,so it can break the granite to form a hole with a diameter of about 52 mm with a low bulge.The results show that the straight-rotating mixed abrasive jet combines the advantages of the cone-straight jet and the rotary jet,and is more suitable for the RJD technology.The research results can provide reference for the development of efficient rock-breaking and hole-forming technology,and promote the development of RJD technology in the field of geothermal development.展开更多
基金Medical Science and Technology Tackling Program Project of Henan Province[RKX202402028].
摘要Objectives:Missed nursing care is a widespread issue in clinical practice and represents a global challenge.Reducing missed nursing care is crucial for improving care quality and implementing high-quality nursing services.This study conducted a longitudinal survey among clinical nurses to investigate the impact and underlying mechanisms of the nursing work environment,moral sensitivity,and humanistic care ability on missed nursing care,aiming to provide theoretical evidence for optimizing the work environment and enhancing nursing quality.Methods:From October 2024 to April 2025,a longitudinal survey was conducted at three time points among 989 clinical nurses using the Nursing Work Environment Scale,Missed Nursing Care Scale,Moral Sensitivity Questionnaire,and the Nurse Humanistic Care Ability Scale.A total of 902 valid responses were included in the final analysis.Structural equation modeling and mediation pathway analysis were performed using AMOS 26.0,and data analysis was conducted using SPSS 25.0.Results:The mean score of missed nursing care among clinical nurses was 43.10±15.87.The clinical nursing work environment was negatively correlated with missed nursing care(r=−0.502,P<0.01),and positively correlated with both moral sensitivity(r=0.241,P<0.01)and humanistic care ability(r=0.312,P<0.01).Moral sensitivity was positively correlated with humanistic care ability(r=0.228,P<0.01)and negatively correlated with missed nursing care(r=−0.430,P<0.01).Furthermore,humanistic care ability was negatively correlated with missed nursing care(r=−0.526,P<0.01).Moral sensitivity and humanistic care ability served as a chain mediating pathway between the nursing work environment and missed nursing care(β=−0.015,P<0.001),and the overall model demonstrated good fit indices.Conclusion:The clinical nursing work environment is a key factor influencing missed nursing care.Moral sensitivity and humanistic care ability among nurses act as a mediating mechanism linking the nursing work environment to missed nursing care.Therefore,healthcare administrators may consider strengthening nurses’moral sensitivity and humanistic care capacity as strategic entry points for developing targeted interventions to reduce missed nursing care.
基金Project supported by the National Natural Science Foundation of China(22408229)National Key R&D Program of China(2023YFB3507100)Science and Technology Major Project Inner Mongolia Autonomous Region in China(2019ZD023,2021ZD0028)。
摘要Developing high-performance catalysts that possess both strong oxidation and reduction capabilities remains a big challenge.Herein,a multi-level complex heterostructure system with both heterojunction and heterophase junction(hollow core-shell CeO2@t-BiVO4/m-BiVO4)was developed.Vacancymediated active electron transfer behavior between low-valent metal elements simultaneously enhances photocatalytic oxidation and reduction properties,ultimately achieving a 4.25-fold increase in oxidation capability and a 4.56-fold increase in reduction capability.The reason that the heterostructure system is more favorable for multi-electron transfer processes is owing to the abundant oxygen vacancies(Ov)and the flexible Ce3+/Ce4+redox behavior in CeO2.Notably,the rapid interconversion of Ce3+/Ce4+can accelerate the effective transfer and efficient utilization of photogenerated electrons.Concurrently,the transfer of electrons from Ce3+to Bi3+,Ovand V4+sites enhances the separation ability of photogenerated charge carriers and effectively reduces the high recombination caused by localized electron enrichment,which is the key to the significant enhancement of both oxidation and reduction capabilities.This study is expected to provide new insights into the design of high-performance photocatalysts capable of effectively addressing the challenges of water pollution and CO2reduction.
基金supported by the National Natural Science Foundation of China(Grant Nos.12305054 and 12572032)the Guangdong Provincial Key Laboratory of Mathematical and Neural Dynamical Systems(Grant No.2024B1212010004)the Fundamental Research Funds for Central Universities,China University of Geosciences(Wuhan)(Grant No.CUGQT2023001)。
摘要Working memory is a fundamental aspect of brain cognitive function.Its anti-interference ability relies on the network structure and the balance between excitatory and inhibitory neurons in neural systems.Here,we discuss the resistance of the spiking neuron-astrocyte network(SNAN)to noise interference of the input signal during working memory tasks,and we underscore that astrocytes play an essential regulatory role in synaptic plasticity.These results indicate that,compared to the SNAN and spiking neuron network(SNN),the improved SNAN incorporated 2-Arachidonoylglycerol(2-AG)modulation displays notable resistance to high noise interference.The improved SNAN shows optimal working memory performance,demonstrating a greater correlation between recalled patterns and input patterns.This may be due to the reduced connection sparsity of the neural network and decreased neural firing frequency caused by 2-AG,as well as its simultaneous impact on the secretion of glutamate.At the same time,astrocytes affecting memory maintenance generate overlapping calcium signals in multi-task working memory.In addition,astrocytes can significantly enhance working memory performance by modulating synaptic coupling under high noise interference.This study may provide insights into understanding the role of astrocytes in the neural mechanisms of working memory and information processing.
基金supported by the National Natural Science Foundation of China(82304466)the China Postdoctoral Science Foundation(2023T160070 and 2023M740372)Postgraduate Research&Practice Innovation Program of Jiangsu Province(JX10114060).
摘要Early social isolation(SI)impairs social ability,which can be partially rescued after resocialization,but the underlying mechanisms have been rarely addressed.This study reported that adolescent SI mice resocialized with group housing(GH)mice,but not with SI mice,showed improved social behavior performances,increased myelination in the medial prefrontal cortex(mPFC),and upregulated Egr2 expression in oligodendrocytes(OLs).Specific downregulation of OL Egr2 in GH companions or overexpression of OL Egr2 in SI peers abolished or rescued their repair effects on mPFC hypomyelination and social ability defects in SI mice,respectively.Furthermore,the improving effect of GH companions on OL Egr2 expression and myelinogenesis in the mPFC of SI mice was abolished when GH mice were treated with corticosterone.RNA-sequencing analysis showed that Egr2 enhanced myelination by inhibiting PDGFRα.Together,these results revealed that the Egr2/PDGFRαaxis mediates distinct peer effects in rescuing SIinduced hypomyelination and social ability impairment.
基金funded by the Hainan Province Agricultural Reclamation Team Joint Innovation Project(Grant No.HKKJ202432)the National Key Research and Development Program Project(Grant No.2023YFD2300803–7)Hainan University Mango Industry Technology System Construction Project.
摘要Mango(Mangifera indica)is a tropical,climacteric fruit with unique flavor and rich nutrition,but its postharvest shelf life is limited due to softening,rotting,and cold damage susceptibility.Recent research indicates that storage at 12℃ can preserve mango fruit well,but the underlying preservation mechanism remains poorly understood.In this study,postharvest quality changes and antioxidant mechanism of‘Tainong No.1'mango stored at 12 and 30℃ with 90%±5%RH for 24 d were explored.The results showed that,compared with storage at 30℃,storage at 12℃ significantly maintained fruit firmness,while reducing weight loss rate and malondialdehyde(MDA)content.Better cell morphology and delayed starch degradation were found at 12℃ through microscopic analysis.Moreover,the mango fruit stored at 12℃ showed significantly enhanced activities of antioxidant enzymes,including peroxidase(POD),superoxide dismutase(SOD),phenylalanine ammonia lyase(PAL),and ascorbate peroxidase(APX).Induced expressions of enzyme genes supported the corresponding enhanced enzyme activities.Furthermore,correlation analysis demonstrated that SOD,total phenols,and flavonoids might have a greater contribution to balancing the ROS homeostasis of postharvest mangoes.These findings suggest that storage at 12℃ might maintain mango quality and prolong the storage period by regulating fruit antioxidant capacity.
摘要Background:Maternal mental health literacy is a cognitive resource that may support preschoolers’emotional development,yet its influence on emotional regulation and the related mechanisms remains unclear.This study examined whether maternal depressive mood and democratic parenting form a chain pathway linking maternal mental health literacy to preschoolers’emotional regulation ability.Methods:Mothers of 544 preschoolers in China’s Mainland completed an online questionnaire that assessed maternal mental health literacy,depressive mood,democratic parenting,and child emotional regulation.Structural path analysis was conducted with child age and gender controlled.Indirect effects were tested using 5000 bootstrap samples.Results:Maternal mental health literacy did not directly predict preschoolers’emotional regulation.Three indirect effects were significant.The pathway through depressive mood had an effect of 0.005,the pathway through democratic parenting had an effect of 0.004,and the chain pathway through depressive mood and democratic parenting had an effect of 0.002.All confidence intervals excluded 0.Conclusion:Maternal mental health literacy influences preschoolers’emotional regulation only through maternal depressive mood and democratic parenting,indicating that cognitive resources affect child emotional outcomes through emotional and behavioral processes rather than a direct pathway.
基金Supported by Guangxi Degree and Postgraduate Education Reform Project(JGY2023213).
摘要In response to the practical problems of insufficient cultivation of innovative thinking,weak practical application ability,and fragmented research training systems among current pharmacy undergraduates,this study constructs a theoretical model of synergistic education characterized by"competitiondriven innovation,innovationdriven learning,and deep integration of competition and innovation",using disciplinary competitions and the College Student Innovation and Entrepreneurship Training Program(College Student Innovation Program)as dual core carriers.Through the coordinated integration of disciplinary competition resources,optimization of the toplevel design of the College Student Innovation Program,establishment of interdisciplinary practical platforms,and construction of a wholeprocess diversified evaluation system,the core abilities of pharmacy undergraduates including scientific research thinking,practical operation,teamwork,and innovation achievement transformation are systematically strengthened.Based on the inherent laws of cultivating innovative pharmaceutical talents and the development needs of the pharmaceutical industry,this study explores the theoretical reconstruction of educational pathways,providing a referenceable and scalable theoretical framework and implementation paradigm for the cultivation of innovative pharmaceutical talents in the new era.
基金Scientific Research Plan Project of Tianjin Municipal Education Commission(2023SK011)。
摘要Objective:This study aims to understand the medical science popularization abilities of medical students and their influencing factors,providing a reference for improving medical students’medical science popularization capabilities.Methods:From November 2024 to January 2025,310 medical students from Tianjin,Baotou,Fuzhou,and Yinchuan were selected as the study subjects.Surveys were conducted using a general information questionnaire and an evaluation scale for medical students’medical science popularization abilities.Results:The median score for medical science popularization abilities among the 310 medical students was 172(interquartile range:159,198).Multiple linear regression analysis revealed that the students’place of origin,grade level,and whether they had experience in medical science popularization were the primary influencing factors,accounting for 10%of the total variance.Conclusion:Medical students’medical science popularization abilities are at a moderate level.School administrators need to develop targeted intervention measures based on these influencing factors to enhance medical students’medical science popularization capabilities.
基金The 2025 Annual Teaching Quality and Teaching Reform Project of Guangdong University of Science and Technology“Evaluation System and Enhancement Strategies for TPACK Competencies of Teachers in Application-Oriented Universities from the Perspective of Intelligent Teaching Collaboration”(GKZLGC2025155)。
摘要Intelligent technology and digital education strategy are profoundly reshaping the teaching paradigm of application-oriented colleges and universities,and putting forward new requirements for teachers’teaching ability.This paper systematically analyzes the three transformation trends of teaching objectives turning to ability generation,teaching scene extending to open ecology,and technology role upgrading as core empowerment,and then analyzes the multi-dimensional ability challenges faced by teachers from the four dimensions of goal design,process control,technology integration,and role transformation.The research points out that to meet these challenges,it is necessary to build integrated practice-oriented teacher development content,create a school-based support environment for collaborative innovation,and improve the teaching evaluation and incentive mechanism with clear guidance.This paper aims to provide a reference for the theoretical construction and practical improvement of teachers’ability development in application-oriented universities.
基金Supported by Chongqing Health Commission and Chongqing Science and Technology Bureau,No.2023MSXM182。
摘要Rheumatoid arthritis(RA)patients face significant psychological challenges alongside physical symptoms,necessitating a comprehensive understanding of how psychological vulnerability and adaptation patterns evolve throughout the disease course.This review examined 95 studies(2000-2025)from PubMed,Web of Science,and CNKI databases including longitudinal cohorts,randomized controlled trials,and mixed-methods research,to characterize the complex interplay between biological,psychological,and social factors affecting RA patients’mental health.Findings revealed three distinct vulnerability trajectories(45%persistently low,30%fluctuating improvement,25%persistently high)and four adaptation stages,with critical intervention periods occurring 3-6 months postdiagnosis and during disease flares.Multiple factors significantly influence psychological outcomes,including gender(females showing 1.8-fold increased risk),age(younger patients experiencing 42%higher vulnerability),pain intensity,inflammatory markers,and neuroendocrine dysregulation(48%showing cortisol rhythm disruption).Early psychological intervention(within 3 months of diagnosis)demonstrated robust benefits,reducing depression incidence by 42%with effects persisting 24-36 months,while different modalities showed complementary advantages:Cognitive behavioral therapy for depression(Cohen’s d=0.68),mindfulness for pain acceptance(38%improvement),and peer support for meaning reconstruction(25.6%increase).These findings underscore the importance of integrating routine psychological assessment into standard RA care,developing stage-appropriate interventions,and advancing research toward personalized biopsychosocial approaches that address the dynamic psychological dimensions of the disease.
基金Supported by Henan Provincial Science and Technology Research Project,No.242102311120。
摘要BACKGROUND Lower extremity arteriosclerotic occlusive disease(LEAOD)is a prevalent chronic vascular condition that significantly increases the risk of lower limb dysfunction and depressive symptoms.Mindfulness-based interventions have demonstrated efficacy in improving mood and coping ability in patients with various chronic illnesses;however,their specific impact on the dual burden of depression and walking ability in patients with LEAOD remains unclear.AIM To explore mindfulness training impact on depression scores and walking ability in patients with LEAOD complicated with depression.METHODS From September 2023 to October 2025,176 patients with LEAOD and depression were enrolled and divided into the control(routine treatmentursing,n=93)and study(mindfulness training plus routine treatmentursing,n=83)groups.Baseline confounding factors were balanced between the groups using 1:1 propensity score matching,with 62 cases in each group.Depression scores,walking ability,self-efficacy,quality-of-life,and complications were compared between the two groups before the intervention,8 weeks after the intervention,and at 1 month follow-up.RESULTS After 8 weeks of intervention and at 1 month follow-up,the Self-Rating Depression Scale score of the intervention group were 37.21±5.32 and 30.76±4.94 points,respectively,which were significantly lower than those of the control group(44.68±5.77 and 38.94±5.13 points)(P<0.05).The pain-free walking distance in the intervention group were 243.06±13.44 m and 263.35±11.52 m,respectively,and the six-minute walk distances were 387.24±15.22 m and 426.55±13.02 m,respectively,both of which were higher than those of the control group(pain-free walking distance:224.55±11.87 m and 244.56±10.43 m;six-minute walk distances:364.45±13.34 m and 307.06±10.73 m)(P<0.05).The Chinese Self-Efficacy Exercise Scale and MOS36-item short form health survey scores of the two groups were significantly higher than those before the intervention(P<0.05).The total complication rate in the intervention group was 3.23%lower than that in the control group(14.52%)(P<0.05).CONCLUSION Mindfulness training effectively alleviated depression and enhanced walking ability,self-efficacy,and quality-oflife in patients with LEAOD concomitant with depression,suggesting a valuable supplementary rehabilitation intervention.
基金Innovation Project of Guangxi Graduate Education(No.JGY2020105)。
摘要As outstanding talents of higher education in China,postgraduates majoring in ethnic medicine should have their career development ability cultivated.This study explores countermeasures to improve the professional ability training of ethnic medicine postgraduates,helping them establish correct career awareness and conduct reasonable career planning,so as to improve competitiveness in the increasingly severe employment situation and solve the employment difficulties of ethnic medicine postgraduates,which can make positive contributions to the medical and health undertakings of the motherland.It is highly necessary to cultivate postgraduates’professional ability and guide reasonable career planning.
基金supported by the Comprehensive Reform and Development of Graduate Education at the Graduate School of the China Academy of Chinese Medical Sciences.
摘要Medical research and human health are deeply connected,and international medical exchanges play a important role in raising research level.This study employs bibliometric and visual analytic approaches to identify effective strategies for improving international medical collaborations.We retrieved relevant literature from the Web of Science Core Collection,including SCI-Expanded,SSCI,CPCI-S,and CPCI-SSH databases,covering the period 1992-2022.CiteSpace software was utilized to generate knowledge visualization maps.A total of 443 articles were included in the analysis.The number of publications related to international educational exchange in medicine has grown steadily over time.Keyword co-occurrence analysis identified“international educational exchange,”“higher education,”“healthcare,”and“global health”as the most prevalent terms.Remote online training has emerged as a prevalent modality for international educational exchange and cooperation.Technologies leveraging computer networks for platform-based learning have attained increasing sophistication.Future international collaboration will be characterized by openness,resource-sharing,diversity,and digitalization(intelligence).
摘要This study aimed to evaluate the application of the problem-based learning(PBL)teaching method in emergency ultrasound training,specifically its effect on improving rapid diagnostic ability and learning outcomes.From May 2020 to May 2025,40 emergency ultrasound resident doctors were randomly selected and divided into a control group(n=20,receiving conventional teaching)and an observation group(n=20,receiving PBL teaching).After training,the observation group scored significantly higher than the control group in both rapid diagnostic ability for emergency ultrasound(including static image/dynamic video interpretation,standard section acquisition,rapid screening process and timeliness,quality of written diagnostic reports,and clinical decision support)and learning effect scores(learning interest,learning initiative,and self-confidence),with all differences showing statistical significance(p<0.05).In conclusion,the application of the PBL teaching method in emergency ultrasound training for resident doctors effectively enhances their rapid diagnostic ability and learning outcomes.
摘要Objective:To explore the impact of narrative medicine writing intervention on the empathy ability and job burnout of residents undergoing standardized training in oncology(referred to as“standardized training”),and to provide empirical evidence for optimizing the standardized training system in oncology.Methods:A total of 70 trainees who received standardized training in the oncology department of our hospital from January 2024 to June 2025 were selected as the study subjects.They were divided into an observation group and a control group with 35 cases each according to the random number table method.The control group received routine standardized training in oncology,while the observation group received additional narrative medicine writing training on the basis of routine standardized training.Baseline data of the two groups were statistically analyzed,and the empathy ability and job burnout levels of the trainees in both groups were evaluated before the intervention(January 2024)and after the intervention(June 2025),respectively.Results:Before the intervention,there were no statistically significant differences in demographic characteristics such as gender,age,educational background,and rotation duration between the two groups of trainees(all P>0.05).After the intervention,the total score and scores in each dimension of the JSE-HP in the observation group were significantly higher than those in the control group,and the scores in the observation group after the intervention were significantly higher than those before the intervention(all P<0.001).After the intervention,the scores in the dimensions of emotional exhaustion and cynicism in the observation group were significantly lower than those in the control group,while the score in the dimension of reduced professional efficacy was significantly higher than that in the control group.Moreover,in the observation group,the scores in emotional exhaustion and cynicism decreased significantly after the intervention,and the score in reduced professional efficacy increased significantly(all P<0.001).After the intervention,the total score of the JSE-HP in the observation group showed a significant negative correlation with the emotional exhaustion dimension of the MBI-GS(r=-0.664,P<0.001),a significant negative correlation with the cynicism dimension(r=-0.571,P<0.001),and a significant positive correlation with the reduced professional efficacy dimension(r=0.425,P<0.001).Conclusion:Narrative medicine writing can effectively enhance the empathy ability of trainees in standardized training programs for oncology and reduce their level of job burnout,making it worthy of promotion and application in the standardized training system for oncology.
基金Chongqing Education Science Planning Project.Project Name:Research on Talent Training of Community Rehabilitation Major in Higher Vocational Colleges Based on OBE Concept(Project No.:K23ZG3420222)。
摘要Objective:To analyze the improvement effect of early postoperative rehabilitation training on balance ability and quality of life in elderly patients with hip fracture.Methods:A total of 50 elderly patients with hip fracture admitted to our hospital from January 2023 to January 2024 were selected and divided into the observation group(25 cases)and the control group(25 cases)by random number table method.The control group received routine nursing,while the observation group received early rehabilitation training on the basis of routine nursing.The balance ability(Berg Balance Scale,BBS)and quality of life(SF-36)of the two groups were compared.Results:The BBS scores of the observation group at all postoperative time points were significantly higher than those of the control group(p<0.05),and the quality-of-life scores of the observation group were also significantly higher than those of the control group(p<0.05).Conclusion:Early postoperative rehabilitation training for elderly patients with hip fracture can improve their balance ability,enhance their quality of life,and reduce the incidence of postoperative complications,which is worthy of clinical promotion.
摘要Objective:To explore the intervention effect of the bidirectional quality feedback nursing model on the quality of life and self-management ability of patients with chronic obstructive pulmonary disease(COPD).Methods:A total of 60 COPD cases in the stable phase of the disease admitted to our hospital from January to December 2024 were included.Using a random number table method,they were divided into a control group and an observation group,with 30 cases in each group.The control group received the standard nursing protocol,while the observation group underwent a three-month bidirectional quality feedback nursing intervention in addition to the standard protocol.The quality of life and self-management ability scores of the two groups were compared before and after the intervention.Results:After the intervention,compared with the control group,the observation group showed lower scores in all dimensions of the St.George’s Respiratory Questionnaire(SGRQ)and higher scores in all domains and the total score of the Self-Care of Chronic Illness Inventory-Modified for COPD(SCMMS)(p<0.05).Conclusion:The bidirectional quality feedback nursing intervention can significantly improve the self-care level and quality of life of patients with COPD,demonstrating clinical application value.
基金2023 Shandong Provincial Educational and Teaching Research Project(Project No.:2023JXY154)。
摘要Guided by the National Vocational College Skills Competition Teaching Ability Competition,this paper selects the“Object Detection”teaching unit and elaborates on the teaching design and practice process in detail from aspects such as overall teaching design,teaching implementation process,students’learning effects,and reflection and improvement measures.By introducing real application scenarios of smart factories,it cultivates students’craftsman spirit of striving for excellence and sense of responsibility to serve the country through science and technology,providing experience and reference for transporting high-quality technical and skilled talents for the high-quality development of the artificial intelligence industry.
基金supported by the China Agriculture Research System of MOF and MARA(CARS-42-4)School Cooperation Project of Ya’an(21SXHZ0028)the Key Technology Support Program of Sichuan Province,China(2021YFYZ0014),for the financial support。
摘要The low egg production of goose greatly limits the development of the industry.China possesses the most abundant goose breeds resources.In this study,genome resequencing data of swan goose(Anser cygnoides)and domesticated high and low laying goose breeds(Anser cygnoides domestiation)were used to identify key genes related to egg laying ability in geese and verify their functions.Selective sweep analyses revealed 416 genes that were specifically selected during the domestication process from swan geese to high laying geese.Furthermore,SNPs and Indels markers were used in GWAS analyses between high and low laying breed geese.The results showed that RTCB,BPIFC,SYN3,SYNE1,VIP,and ESR1 may be related to the differences in laying ability of geese.Notably,only ESR1 was identified simultaneously by GWAS and selective sweep analysis.The genotype of Indelchr3:54429172,located downstream of ESR1,was confirmed to affect the expression of ESR1 in the ovarian stroma and showed significant correlation with body weight at first egg and laying frequency of geese.CCK-8,EdU,and flow cytometry confirmed that ESR1 can promote the apoptosis of goose pre-hierarchical follicles ganulosa cells(phGCs)and inhibit their proliferation.Combined with transcriptome data,it was found ESR1 involved in the function of goose phGCs may be related to MAPK and TGF-beta signaling pathways.Overall,our study used genomic information from different goose breeds to identify an indel located in the downstream of ESR1 associated with goose laying ability.The main pathways and biological processes of ESR1 involved in the regulation of goose laying ability were identified by cell biology and transcriptomics methods.These results are helpful to further understand the laying ability characteristics of goose and improve the egg production of geese.
基金funded by the National Natural Science Foundation of China(No.52374018)Science Foundation of China University of Petroleum,Beijing(No.2462021YJRC009)。
摘要Radial jet drilling(RJD)technology is expected to be a technology for the efficient exploitation of geothermal resources.However,the low rock-breaking efficiency is the major obstacle hindering the development of RJD technology.The flow field characteristics and rock breaking ability of cone-straight abrasive jet,rotary abrasive jet,and straight-rotating mixed abrasive jet are analyzed by numerical simulations and experiments.Results show that the axial velocity of the cone-straight abrasive jet is high,the tangential velocity is basically zero,the radial velocity is also small,and the jet impact area is concentrated in the center.A deep hole with a diameter of only 25 mm is formed when the cone-straight abrasive jet breaks the granite.Due to the presence of the guiding impeller,the rotary abrasive jet basically has no axial velocity and has the highest tangential and radial velocity,so it can break the granite to form a hole with a diameter of about 55 mm and a central bulge.The straight-rotating mixed abrasive jet has a large axialangentialadial velocity at the same time,so it can break the granite to form a hole with a diameter of about 52 mm with a low bulge.The results show that the straight-rotating mixed abrasive jet combines the advantages of the cone-straight jet and the rotary jet,and is more suitable for the RJD technology.The research results can provide reference for the development of efficient rock-breaking and hole-forming technology,and promote the development of RJD technology in the field of geothermal development.