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Effects of Respiratory Function Training on Pulmonary Function and Recurrence of Wheezing Diseases in Children 认领 引用
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作者 Shilan Chen Rong Feng +1 位作者 Yan Chen Yuehong Li 《Journal of Clinical and Nursing Research》 2026年第6期308-315,共8页
Objective:To explore the clinical application effects of respiratory function training on children with wheezing diseases.Methods:A total of 96 children with wheezing diseases admitted to Yancheng Maternity and Child ... Objective:To explore the clinical application effects of respiratory function training on children with wheezing diseases.Methods:A total of 96 children with wheezing diseases admitted to Yancheng Maternity and Child Healthcare Hospital from January 2025 to March 2026 were enrolled and divided into a control group and an observation group by random number table,with 48 cases in each group.The control group received conventional treatment and routine nursing.On the basis of conventional interventions,the observation group was given additional respiratory function training for a total of 3 months.Pulmonary function indicators,wheezing recurrence rate,readmission rate,and nursing satisfaction were compared between the two groups before and after intervention.Results:After intervention,the levels of FEV1,FVC,and PEF in the observation group were superior to those of the control group.The wheezing recurrence rate was lower,while the nursing satisfaction was higher in the observation group,with all differences being statistically significant.Conclusion:Respiratory function training can effectively improve pulmonary function,reduce wheezing recurrence,and raise nursing satisfaction among children with wheezing diseases.It is worthy of clinical promotion. 展开更多
关键词 Respiratory function training Childhood wheezing diseases Pulmonary function
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Effect of vocal respiratory training on respiratory function and respiratory neural plasticity in patients with cervical spinal cord injury:a randomized controlled trial 认领 引用 被引量：9
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作者 Xiao-Ying Zhang Wei-Yong Yu +7 位作者 Wen-Jia Teng Yi-Chuan Song De-Gang Yang Hong-Wei Liu Song-Huai Liu Xiao-Bing Li Wen-Zhu Wang Jian-Jun Li 《Neural Regeneration Research》 SCIE CAS CSCD 2022年第5期1065-1071,共7页
In previous studies,researchers have used singing to treat respiratory function in patients with spinal cord injury.However,few studies have examined the way in which vocal training affects respiratory neural plastici... In previous studies,researchers have used singing to treat respiratory function in patients with spinal cord injury.However,few studies have examined the way in which vocal training affects respiratory neural plasticity in patients with spinal cord injury.Vocal respiratory training(VRT)is a type of vocal muscle-related treatment that is often a component of music therapy(MT)and focuses on strengthening respiratory muscles and improving lung function.In this randomized controlled study,we analyzed the therapeutic effects of VRT on respiratory dysfunction at 3 months after cervical spinal cord injury.Of an initial group of 37 patients,26 completed the music therapy intervention,which comprised five 30-minute sessions per week for 12 weeks.The intervention group(n=13)received VRT training delivered by professional certified music therapists.The control group(n=13)received respiratory physical therapy delivered by professional physical therapists.Compared with the control group,we observed a substantial increase in respiratory function in the intervention group after the 12-week intervention.Further,the nerve fiber bundles in the respiratory center in the medulla exhibited a trend towards increased diversification,with an increased number,path length,thickness,and density of nerve fiber bundles.These findings provide strong evidence for the effect of music therapeutic VRT on neural plasticity.This study was approved by the Ethics Committee of China Rehabilitation Research Center(approval No.2020-013-1)on April 1,2020,and was registered with the Chinese Clinical Trial Registry(registration No.Chi CTR2000037871)on September 2,2020. 展开更多
关键词 cervical spinal cord injury music therapy neural plasticity respiratory center respiratory function vocal respiratory training
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Analysis of the impact of ERAS-based respiratory function training on older patients’ability to prevent pulmonary complications after abdominal surgery 认领 引用 被引量：2
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作者 Yue-Xia Gu Xin-Yu Wang +2 位作者 Mei-Xia Xu Jia-Jie Qian Yan Wang 《World Journal of Gastrointestinal Surgery》 SCIE 2023年第2期201-210,共10页
BACKGROUND In China,as the population grows older,the number of elderly people who have died from respiratory problems has increased.AIM To investigate whether enhanced recovery after surgery(ERAS)-based respiratory f... BACKGROUND In China,as the population grows older,the number of elderly people who have died from respiratory problems has increased.AIM To investigate whether enhanced recovery after surgery(ERAS)-based respiratory function training may help older patients who had abdominal surgery suffer fewer pulmonary problems,shorter hospital stays,and improved lung function.METHODS The data of 231 elderly individuals having abdominal surgery was retrospectively analyzed.Based on whether ERAS-based respiratory function training was provided,patients were divided into ERAS group(n=112)and control group(n=119).Deep vein thrombosis(DVT),pulmonary embolism(PE),and respiratory tract infection(RTI)were the primary outcome variables.Secondary outcome variables included the Borg score Scale,FEV1/FVC and postoperative hospital stay.RESULTS The percentage of 18.75%of ERAS group participants and 34.45%of control group participants,respectively,had respiratory infections(P=0.007).None of the individuals experienced PE or DVT.The ERAS group’s median postoperative hospital stay was 9.5 d(3-21 d)whereas the control groups was 11 d(4-18 d)(P=0.028).The Borg score decreased on the 4th d following surgery in the ERAS group compared to the 2nd d prior(P=0.003).The incidence of RTIs was greater in the control group than in the ERAS group among patients who spent more than 2 d in the hospital before surgery(P=0.029).CONCLUSION ERAS-based respiratory function training may reduce the risk of pulmonary complications in older individuals undergoing abdominal surgery. 展开更多
关键词 Pulmonary complications Respiratory function training Enhanced recovery after surgery Abdominal surgery
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Effect of nursing on postoperative respiratory function and mental health of lung cancer patients 认领 引用 被引量：6
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作者 Xiang Yang Dan Yin Shi-Qing Chen 《World Journal of Clinical Cases》 SCIE 2024年第5期922-930,共9页
BACKGROUND Both pulmonary rehabilitation training and psychological care have been shown to have a positive effect on the postoperative recovery of patients with lung cancer.However,few studies have combined the two t... BACKGROUND Both pulmonary rehabilitation training and psychological care have been shown to have a positive effect on the postoperative recovery of patients with lung cancer.However,few studies have combined the two to explore their combined effect.Therefore,this study aimed to investigate the effects of pulmonary rehabil-itation training combined with psychological care on postoperative respiratory function and mental health in lung cancer patients.AIM To investigate effect of nursing on postoperative respiratory function and mental health of lung cancer patients.METHODS 122 cases of lung cancer patients who underwent surgical treatment in our hospital and were treated in our department from January 2022 to April 2023 were selected and randomly divided into the control group and observation group.The control group performed the routine care intervention.The obser-vation group was given pulmonary rehabilitation training and psychological care based on conventional nursing interventions.Forced expiratory volume,forced vital capacity.Maximum ventilatory volume(MVV)in one second was measured,and the patient's 6-min walking distance and dyspnoea index scale were used to assess the patient's respiratory condition.The Connor-Davidson resilience scale(CD-RISC),self-rating anxiety scale(SAS),and self-rating depression scale(SDS)were used to evaluate the mental health of the patients.RESULTS There was no difference between the two groups regarding age,gender,education level,surgical procedure,type of pathology,and treatment(P>0.05).After treatment,MVV,6-min walking distance,toughness,strength,optimism,and total CD-RISC scores were significantly higher in the observation group(P<0.05),dyspnoea scores,SAS,and SDS scores were substantially lower in the control group compared to the observation group(P<0.05).CONCLUSION Pulmonary rehabilitation training combined with psychological care for patients after lung cancer resection could improve lung function,enhance daily activities,effectively relieve negative emotions such as anxiety and depression,and reduce complications. 展开更多
关键词 Pulmonary rehabilitation training Psychological care Lung cancer Postoperative care Respiratory function
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Effects of Video Combined with the Teach-Back Method on the Respiratory Function Exercise of Patients Undergoing Thoracotomy 认领 引用 被引量：2
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作者 Heping Wu Juan Yuan Lihong Qiu 《Journal of Cancer Therapy》 2022年第5期243-251,共9页
Objective: To explore the effect of video combined with the teach-back method on respiratory function exercise in patients undergoing tumor thoracotomy. Methods: Eligible patients undergoing thoracotomy for tumor were... Objective: To explore the effect of video combined with the teach-back method on respiratory function exercise in patients undergoing tumor thoracotomy. Methods: Eligible patients undergoing thoracotomy for tumor were selected from the thoracic surgery at a level-A tertiary hospital between August 2021 and December 2021 and included in the control group and the observation group (40 patients in each group). To prevent two groups of patients from interacting with each other, the thoracic surgery ward I was distinguished as the control group, which was adopted by the routine instruction. Based on routine instruction, the thoracic surgery ward II conducted respiratory function exercise instruction by video combined with the teach-back method to compare the two groups’ compliance with respiratory function exercise, complication rates, and patient satisfaction. Results: The patient compliance with respiratory function exercise in the observation group was significantly higher (P < 0.05) and the rate of pulmonary complications in the observation group was lower (P < 0.05) than that in the control group, while the observation group had a high level of satisfaction (P Conclusion: Taking video combined with the teach-back method, an effective health education method, can improve the compliance of the respiratory function exercise of patients undergoing thoracotomy for tumor and promote the recovery of pulmonary function to reduce the incidence of postoperative pulmonary complications so as to improve patient satisfaction. 展开更多
关键词 Respiratory Function Exercise Video Education Teach-Back Method
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The Relationship between Gait Asymmetry and Respiratory Function in Stroke Patients: A Pilot Study 认领 引用 被引量：1
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作者 Yoshino Terui Satomi Iwasawa +5 位作者 Kazuto Kikuchi Yutaka Furukawa Eriko Suto Sachiko Uemura Masahiro Satake Takanobu Shioya 《Open Journal of Therapy and Rehabilitation》 2021年第4期111-122,共12页
INTRODUCTION: Gait asymmetry can become very pronounced in patients who have suffered a stroke. The impairment of trunk function in some stroke patients can restrict thorax mobility and cause respiratory muscle weakne... INTRODUCTION: Gait asymmetry can become very pronounced in patients who have suffered a stroke. The impairment of trunk function in some stroke patients can restrict thorax mobility and cause respiratory muscle weakness. Trunk and neck dysfunction are believed to affect the gait in stroke patients. OBJECTIVE: This study aimed to investigate the relationship between gait asymmetry and respiratory function in stroke patients by measuring the step time and trunk acceleration. METHODS: This study employed a cross-sec- tional design. Thirty stroke patients participated in this study. The symmetry index (SI) and Lissajous index (LI) were used to evaluate asymmetry during walking. The respiratory function and respiratory muscle strength were evaluated by spirometry. We examined the relation between SI or LI and the respiratory functionespiratory muscle strength in patients with stroke. RE- SULTS: The results of our analysis demonstrated that the SI was significantly correlated with the inspiratory and expiratory muscle strength and the LI was significantly correlated with the percentage of the predicted vital capacity (respectively, r = ﹣0.386, r = ﹣0.392, r = ﹣0.446;p CONCLUSION: The present study is the first to indicate a relationship between gait asymmetry and respiratory function in stroke patients. 展开更多
关键词 Gait Asymmetry Acceleration Load Meter Respiratory Function Stroke
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Analysis of the Effect of Extracorporeal Diaphragmatic Pacing Combined with Noninvasive Ventilator on the Respiratory Function and Prognosis of COPD Patients 认领 引用 被引量：2
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作者 Wei Xu Fei Wang Fang Wang 《Journal of Clinical and Nursing Research》 2024年第4期73-78,共6页
Objective: To investigate the effect of extracorporeal diaphragmatic pacing combined with noninvasive ventilators on the respiratory function and prognosis of chronic obstructive pulmonary disease (COPD) patients. Met... Objective: To investigate the effect of extracorporeal diaphragmatic pacing combined with noninvasive ventilators on the respiratory function and prognosis of chronic obstructive pulmonary disease (COPD) patients. Methods: A total of 50 COPD patients were selected between January 2023 to December 2023 and randomly grouped into an observation group and a control group, with 25 cases. The observation group was given extracorporeal diaphragm pacing combined with a noninvasive ventilator, while the control group was given a conventional treatment mode. After the treatment, the results of each index in the two groups were compared. Results: Compared with the diaphragm function indexes of the two groups, the data of the observation group were more dominant (P < 0.05). The rehospitalization rate of the observation group was lower than that of the control group (P < 0.05). The COPD assessment test (CAT) and mMRC (Modified Medical Research Council) Dyspnoea scale scores after treatment between the two groups were significantly different (P < 0.05). Compared with the control group, the lung function indexes of the observation group were more dominant (P < 0.05). Conclusion: Extracorporeal diaphragmatic pacing combined with a noninvasive ventilator promoted the improvement of the patient’s prognosis and improved their respiratory function. 展开更多
关键词 COPD Extracorporeal diaphragmatic pacing Noninvasive ventilator Respiratory function Prognosis
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Effects of Water Immersion in Different Water Depths on Respiratory Function and Respiratory Muscle Strength among Elderly People: An Observational Study 认领 引用
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作者 Yoshihiro Yamashina Tomoko Hirayama +7 位作者 Hiroki Aoyama Hirofumi Hori Emiko Morita Nami Sakagami Wataru Nanikawa Shigeru Terada Masahiro Goto Kazuyuki Tabira 《Advances in Aging Research》 CAS 2021年第4期71-77,共7页
The aim was to investigate the effect of three water levels (umbilical, 4th rib, and clavicular) on the respiratory function and respiratory muscle strength among elderly. Spirometry and respiratory strength were meas... The aim was to investigate the effect of three water levels (umbilical, 4th rib, and clavicular) on the respiratory function and respiratory muscle strength among elderly. Spirometry and respiratory strength were measured on land as baseline data. Next, water depth conditions were determined randomly, and spirometry and respiratory muscle strength were measured at each water level. The Vital Capacity and Expiratory reserve volume in the clavicular level were significantly lower than those in the land and umbilical trials. No significant difference was observed in other respiratory functions. Chest circumference and respiratory muscle strength were not significantly different among all conditions. 展开更多
关键词 Respiratory Functions Respiratory Muscle Strength Water Immersion Elderly People
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Clinical Effect of Aminophylline Combined with Respiratory Function Training on Obstructive Emphysema Complicated with Respiratory Failure 认领 引用
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作者 PIAOYuxin LIUXiaohua 《外文科技期刊数据库（文摘版）医药卫生》 2022年第2期059-062,共4页
Objective: to analyze the effect of combined treatment of obstructive emphysema with respiratory failure by adding respiratory function training on the basis of aminophylline therapy. Methods: in this study, 80 patien... Objective: to analyze the effect of combined treatment of obstructive emphysema with respiratory failure by adding respiratory function training on the basis of aminophylline therapy. Methods: in this study, 80 patients with obstructive emphysema and respiratory failure admitted to our hospital from October 2018 to October 2021 were selected as study members, and divided into two groups, 40 cases in each group. In order to compare the clinical indicators, clinical effects and treatment recognition of the two groups, aminophylline treatment and combined treatment with aminophylline therapy were respectively performed, with the former as the control group and the latter as the study group. Results: after combined treatment, the clinical indicators, clinical effects and treatment recognition of the study group were better than those of the control group (P < 0.05). Conclusion: on the basis of aminophylline treatment, the combined treatment of respiratory function training can improve the therapeutic effect of patients with obstructive emphysema and respiratory failure, and improve the clinical symptoms of most patients. After treatment, the patients' condition has improved, so they feel very satisfied with the treatment. 展开更多
关键词 aminophylline respiratory function training obstructive emphysema respiratory failure
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The Effect of Comfort Care in Improving Respiratory Function of Patients with Pulmonary Heart Disease 认领 引用
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作者 YANG Maogong NIE Jingting 《外文科技期刊数据库（文摘版）医药卫生》 2021年第9期060-062,共3页
Objective: to analyze the clinical value of comfort nursing for patients with cor pulmonale, and to explore the role of improving patients' respiratory function. Methods: 70 cases of cor pulmonale patients admitte... Objective: to analyze the clinical value of comfort nursing for patients with cor pulmonale, and to explore the role of improving patients' respiratory function. Methods: 70 cases of cor pulmonale patients admitted to our hospital in recent one year were selected and their clinical data were studied. The specific time was from April 2020 to April 2021. All patients included in the study were randomly divided into two groups, the research group and the reference group, with 35 patients in each group. Patients who implemented basic nursing procedures were defined as the reference group, and patients who implemented comfort care were defined as the research group to compare the nursing effects. Results: comparing the nursing satisfaction data between the research group and the reference group, the former 100% is higher than the latter 77.14%, P ＜ 0.05. Compared with the reference group, the improvement of respiratory function was better in the research group (P ＜ 0.05). Conclusion: comfort care for patients with pulmonary heart disease has a positive effect on the improvement of respiratory function, with high patient satisfaction and high feasibility. 展开更多
关键词 pulmonary heart disease comfort care respiratory function effect
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Improvement of Respiratory Function in the Nursing of Children with Pneumonia by Targeted Nursing 认领 引用
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作者 ZHOU Qi 《外文科技期刊数据库（文摘版）医药卫生》 2021年第11期617-619,共3页
Objective: to explore the improvement of respiratory function of targeted nursing in children with pneumonia. Methods: 68 children with pneumonia diagnosed from January 2019 to January 2020 were randomly divided into ... Objective: to explore the improvement of respiratory function of targeted nursing in children with pneumonia. Methods: 68 children with pneumonia diagnosed from January 2019 to January 2020 were randomly divided into two groups by number table. Control group had 34 cases of routine nursing, and research group had 34 cases of targeted nursing. Compare the effects. Results: the respiratory function and parental satisfaction ratio of the study group were superior to the control group (P ＜ 0.05). Conclusion: the implementation of targeted nursing in children with pneumonia is beneficial to the improvement of lung function and the proportion of parents' satisfaction. 展开更多
关键词 targeted nursing pediatric pneumonia care respiratory function to improve the
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Effect of Respiratory Function Training on Pulmonary Function in Patients with Rheumatic Heart Disease 认领 引用
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作者 LIUTing XIEJiaxiang 《外文科技期刊数据库（文摘版）医药卫生》 2022年第4期127-131,共5页
Objective: to explore the effect of respiratory function training on improving pulmonary function in patients with rheumatic heart disease. Methods: 61 patients with rheumatic heart disease received by the cardiac sur... Objective: to explore the effect of respiratory function training on improving pulmonary function in patients with rheumatic heart disease. Methods: 61 patients with rheumatic heart disease received by the cardiac surgery department of the hospital from April 11, 2020 to April 11, 2021 were grouped according to the time of elective heart surgery. 30 patients in the traditional group received traditional nursing intervention and 31 patients in the experimental group received respiratory function training. The postoperative pulmonary function and postoperative adverse reactions of the two groups were observed. Results: before nursing, the forced expiratory volume (FEV1), respiratory volume (FVC), the percentage of forced vital capacity in forced vital capacity (FEV1%) in the first second and the level of blood oxygen saturation (SaO2) in the two groups were highly homogeneous. After nursing, the levels of FEV1, FVC, FEV1% and SaO2 in the two groups were higher than those before nursing. FEV1, FVC The level of FEV1% was significantly higher than that of the traditional group, the statistical predictive value showed that there was specificity (P 0.05);The incidence of sputum cough and aspiration pneumonia in the experimental group was lower than that in the traditional group. The statistical prediction results showed that there was specificity (P < 0.05);The comparison of the satisfaction questionnaire between the two groups shows that the average score of the satisfaction questionnaire in the experimental group is higher than that in the traditional group, and the statistical prediction results suggest that there is specificity (P < 0.05). Conclusion: preoperative respiratory function training for rheumatic heart disease is helpful to the recovery of postoperative pulmonary function, reduce postoperative adverse reactions and improve patients satisfaction with medical services, which can be used as an important auxiliary measure before heart surgery. 展开更多
关键词 rheumatic heart disease heart surgery respiratory function training pulmonary function
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Nursing Effect of Individualized Nursing Combined with Respiratory Function Training on Children with Cerebral Palsy 认领 引用
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作者 ZHAO Lei 《外文科技期刊数据库（文摘版）医药卫生》 2021年第11期796-798,共3页
Objective: to analyze the nursing effect of personalized nursing combined with respiratory function training on children with cerebral palsy. Methods: a total of 60 children with cerebral palsy admitted to our hospita... Objective: to analyze the nursing effect of personalized nursing combined with respiratory function training on children with cerebral palsy. Methods: a total of 60 children with cerebral palsy admitted to our hospital from May 2020 to May 2021 were randomly divided into two groups by number table method. The children in the control group were given routine nursing, and the children in the research group were given personalized nursing combined with respiratory function training. Torso control ability assessment (TCMS), daily living ability assessment (ADL), inspiratory pressure MIP and family satisfaction were compared between the two groups before and after nursing. Results: the comparison of torso control ability (TCMS), daily living ability (ADL) and inspiratory pressure MIP between the two groups before nursing, P ＞ 0.05; after nursing, the evaluation of torso control ability (TCMS), daily living ability (ADL) and inspiratory pressure MIP between the two groups were improved, P ＜ 0.05. The family satisfaction of the study group was higher than that of the control group, P ＜ 0.05. Conclusion: personalized nursing combined with respiratory function training has a great impact on children with cerebral palsy, which can effectively improve the children's respiratory function, promote the improvement of their daily living ability, and improve the satisfaction of their family members. It is worth promoting. 展开更多
关键词 personalized nursing respiratory function training children with cerebral palsy nursing effect
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Application of Psychological Nursing in Nursing Care of Elderly Patients with COPD and Its Influence on Respiratory Function 认领 引用
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作者 YANGMinhui 《外文科技期刊数据库（文摘版）医药卫生》 2022年第5期013-017,共5页
Objective: to observe the effect of psychological nursing on clinical respiratory function of elderly patients with chronic obstructive pulmonary disease (COPD). Methods: 50 COPD patients (age ≥65 years old) who were... Objective: to observe the effect of psychological nursing on clinical respiratory function of elderly patients with chronic obstructive pulmonary disease (COPD). Methods: 50 COPD patients (age ≥65 years old) who were treated in the South Hospital of Kunming First People's Hospital during the research period from May 1, 2019 to January 31, 2022 were selected for research. They were divided into routine control group (25 cases, routine nursing) and psychological intervention group (25 cases, psychological nursing plus routine nursing) by the central digital stratification method, and their application values were observed. Results: after application, the respiratory rate of COPD patients in psychological intervention group was lower than that in routine control group, and the peak-to-peak time ratio and peak-to-volume ratio were higher than those in routine control group (P < 0.05). After application, the emotional evaluation score of COPD patients in psychological intervention group was lower than that in routine control group (P < 0.05). After application, the quality of life of COPD patients in psychological intervention group was higher than that in routine control group (P < 0.05). After application, the compliance of COPD patients in psychological intervention group was higher than that in routine control group (P < 0.05). After application, the satisfaction of COPD patients in psychological intervention group was higher than that in routine control group (P < 0.05). Conclusion: patients with COPD (age ≥65 years old) have poor respiratory function and poor quality of life. Implementing psychological nursing measures can optimize their mental health, guide patients to follow a number of nursing measures, improve their respiratory function and improve their quality of life, and make them more satisfied with the nursing work of COPD provided by the hospital. 展开更多
关键词 psychological nursing chronic obstructive pulmonary disease in the elderly respiratory function q
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Periodontitis pathogen Porphyromonas gingivalis promotes chronic obstructive pulmonary disease via affecting neutrophils chemotaxis and function 认领 引用 被引量：1
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作者 Luyao Zhang Huan Tian +4 位作者 Yuanyuan Ma Jing Xu Chang Guo Zuomin Wang Jie Ma 《International Journal of Oral Science》 SCIE CAS CSCD 2026年第1期115-125,共11页
Chronic obstructive pulmonary disease(COPD),a disease responsible for early mortality worldwide,is well accepted to be associated with periodontitis epidemiologically.Although both of the diseases are the multi-microb... Chronic obstructive pulmonary disease(COPD),a disease responsible for early mortality worldwide,is well accepted to be associated with periodontitis epidemiologically.Although both of the diseases are the multi-microbial inflammatory disease,the precise underlying mechanisms by which periodontitis influences the progression of COPD remains largely unknown.Here,we established COPD accompanied with periodontitis mouse models and observed the pronounced progress in pulmonary symptoms and histopathology,cha racterized by poorer respiratory function,thicke ned bronchial walls,and increased neutrophils infiltration in lung tissue.Mechanistically,periodontitis pathogen Porphyromonas gingivalis(P.gingivalis)relocated in the lung through the respiratory tract and LPS from P.gingivalis promoted the secretion of chemokines CXCL2 and G-CSF of alveolar epithelial cells through NF-κB and p38 MAPK pathways to recruit neutrophils.Furthermore,exposure to P.gingivalis of infiltrated neutrophils released matrix metallopeptidase-8(MMP-8)and neutrophil elastase(NE),which aggravated airway inflammation and tissue damage.These findings indicated that periodontitis could exacerbate COPD via its pathogen P.gingivalis,which translocated in the lung and stimulated neutrophil chemotaxis and activation in the lung. 展开更多
关键词 neutrophils chemotaxis pulmonary symptoms histopathology periodontitis neutrophils function chronic obstructive pulmonary disease respiratory function chronic obstructive pulmonary disease copd
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Correlation of diaphragm thickness with pulmonary function test in Parkinson’s disease 认领 引用
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作者 Zeliha Cosgun Emine Afsin +3 位作者 Ramazan Kurul Sule Aydin Turkoglu Melike Elif Kalfaoglu Gulali Aktas 《World Journal of Methodology》 2026年第3期251-258,共8页
BACKGROUND Dopaminergic neurons are lost in Parkinson’s disease(PD),a degenerative neurological condition.While the effects of PD on motor functions are well understood,its impact on respiratory function is less clea... BACKGROUND Dopaminergic neurons are lost in Parkinson’s disease(PD),a degenerative neurological condition.While the effects of PD on motor functions are well understood,its impact on respiratory function is less clear.In PD patients with suspicious pulmonary symptoms,the presence and degree of impairment in lung function often cannot be optimally assessed through pulmonary function tests(PFTs)due to the patients'neurological symptoms.AIM To examine the relationship between diaphragmatic thickness as determined by ultrasonography(US)and conventional PFTs in PD patients.Additionally,we evaluated the potential use of diaphragmatic thickness as an alternative measure for assessing respiratory function in PD patients who are unable to perform PFTs.METHODS A total of 43 PD patients who presented to the clinics between June 15,2021,and June 30,2022,were included.Patients with coronavirus disease 2019 infection history,conditions affecting diaphragmatic motility,recent thoracic or abdominal surgery,or imaging showing restrictive masses were excluded.Demographic data,disease duration,Hoehn-Yahr stage,and medication use were recorded.PFTs were used to evaluate forced vital capacity,forced expiratory volume in the first second,and other parameters,while US was used to measure diaphragmatic thickness.Breathlessness was assessed using the modified medical research council dyspnea scale.RESULTS Significant correlations were found between peak expiratory flow(PEF)and diaphragm fraction(P=0.019),as well as between PEF percentage and diaphragmatic thickness during expiration(P=0.023).In early-stage PD,diaphragmatic thickness during inspiration correlated with oxygen saturation(P=0.048).In advanced-stage PD,PEF and PEF%were significantly correlated with diaphragm thickness during expiration[r=0.405,P=0.049(for PEF);r=0.463,P=0.023(for PEF%)]and diaphragm fraction[r=-0.476,P=0.019(for PEF);r=-0.617,P=0.001(for PEF%)].CONCLUSION Present study assessed the relationship between PFTs and diaphragmatic thickness in PD patients.Diaphragmatic thickness measured by US was found to correlate with certain PFT parameters,suggesting it could be used as an alternative measure for assessing respiratory function in Parkinson’s patients who have difficulty performing PFTs. 展开更多
关键词 Parkinson’s disease Ultrasonography Diaphragmatic thickness Pulmonary function test Respiratory function
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Computed tomography-derived assessment of respiratory impairment in thoracic scoliosis:Comparison between idiopathic and non-idiopathic etiologies 认领 引用
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作者 Nanae Tsuchiya Satoko Yogi +5 位作者 Akira Yogi Gyo Iida Koji Yonemoto Takanao Shimabukuro Kotaro Nishida Akihiro Nishie 《World Journal of Radiology》 2026年第6期29-41,共13页
BACKGROUND Thoracic scoliosis causes complex three-dimensional deformities of the thoracic cage that can impair lung mechanics and airway geometry,leading to restrictive ventilatory dysfunction.Respiratory impairment ... BACKGROUND Thoracic scoliosis causes complex three-dimensional deformities of the thoracic cage that can impair lung mechanics and airway geometry,leading to restrictive ventilatory dysfunction.Respiratory impairment differs by etiology,with nonidiopathic scoliosis often showing more severe and persistent deformity.Conventional pulmonary function testing provides global functional assessment but is frequently limited in patients with non-idiopathic scoliosis.Advances in chest computed tomography(CT)allow quantitative evaluation of lung volume and airway morphology,offering an alternative approach to assess respiratory function and the relationship to spinal deformity.AIM To investigate CT-derived airway morphology and respiratory function in thoracic scoliosis,focusing on etiologic differences and structure-function relationships.METHODS This retrospective observational study included 53 patients≤30 years of age who underwent corrective surgery for thoracic scoliosis and had preoperative and postoperative CT examinations.Patients were classified into idiopathic(n=25)or non-idiopathic scoliosis(n=28).Spinal deformity parameters,lung volumes,predicted total lung capacity percentage(TLC%),and airway dimensions were quantified using CT.Group comparisons were performed using the Wilcoxon rank-sum test,correlations were determined using Spearman’s rank correlation,and pre-and postoperative changes were determined using the Wilcoxon signed-rank test.RESULTS Patients with non-idiopathic scoliosis had significantly more severe spinal deformities and a lower TLC%compared to patients with idiopathic scoliosis(median TLC%:39%vs 64%,P<0.001).The Cobb angle was negatively correlated with TLC%(ρ=-0.52,P=0.004),lung volumes,and multiple airway parameters in patients with non-idiopathic scoliosis.Surgical correction significantly improved spinal alignment in both groups.CTderived lung volume parameters did not show significant postoperative changes.In contrast,selective improvement was observed in the left bronchus.CONCLUSION CT-derived analysis showed differences in respiratory impairment between idiopathic and non-idiopathic scoliosis.Surgical correction improved alignment without immediate lung volume improvement,with selective changes in the left bronchus. 展开更多
关键词 Thoracic scoliosis Computed tomography airway analysis Respiratory function Cobb angle Lung volume Three-dimensional imaging
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Effects of magnesium sulfate on brain mitochondrial respiratory function in rats after experimental traumatic brain injury 认领 引用 被引量：6
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作者 许民辉 代文光 邓洵鼎 《Chinese Journal of Traumatology》 EI CAS 2002年第6期361-364,共4页
To study the effects of magnesium sul fate on brain mitochondrial respiratory function in rats after experimental trau matic brain injury and the possible mechanism. Methods: The middle degree brain injury in rats was... To study the effects of magnesium sul fate on brain mitochondrial respiratory function in rats after experimental trau matic brain injury and the possible mechanism. Methods: The middle degree brain injury in rats was made by BIM III multi function impacting machine. The brain mitochondrial respiratory fun ction was measured with oxygen electrode and the ultra structural changes were observed with transmission electron microscope (TEM). Results: 1. The brain mitochondrial respiratory stage III and r espiration control rate reduced significantly in the untreated groups within 24 and 72 hours. But treated Group A showed certain degree of recovery of respirato ry function; treated Group B showed further improvement. 2. Untreated Group, tre ated Groups A and B had different degrees of mitochondrial ultra structural dam age respectively, which could be attenuated after the treatment with magnesium s ulfate.Conclusions: The mitochondrial respiratory function decreases s ignificantly after traumatic brain injury. But it can be apparently improved aft er magnesium sulfate management along with the attenuated damage of mitochondria discovered by TEM. The longer course of treatment can obtain a better improveme nt of mitochondrial respiratory function. 展开更多
关键词 Brain injuries Magnesium Mitochondria Respiratory function tests Rats
The rapeutic Effect of Sheng mai Injection (生脉注射液) on Respiratory Functionin Chronic Obstructive Pulmonary Disease 认领 引用 被引量：2
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作者 方宗君 王丽华 《Chinese Journal of Integrative Medicine》 CAS 2000年第2期101-103,共3页
Objective: To explore the therapeutic effect of shengmai injec tion (SMI) on respiratory function in chronic obstructive pulmonary disease (COPD ).Methods: Twenty patients with COPD were continuously treated w ith SMI... Objective: To explore the therapeutic effect of shengmai injec tion (SMI) on respiratory function in chronic obstructive pulmonary disease (COPD ).Methods: Twenty patients with COPD were continuously treated w ith SMI by intravenous drip for 14 days and their lung vital capacity (VC),for ced vital capacity (FVC),forced vital capacity of the first second (FEV1),FEV1/FVC , maximum voluntary ventilation (MVV), maximum inspiratory pressure (MIP),load respiratory time (LT), 6 minute walk distance (6 MWD), arterial blood gas an alysis, and Borg dyspnea scale were examined respectively before and after treatment a nd compared before and after treatment or with the control group.Results: After treatment all parameters in the treated group were significantly better than those in the control group or than those before treatment (P<0.05) with the exception of FVC and FEV1/FVC. Conclusion: SMI could improve respiratory function in COPD. So i t is an effective rehabilitative injection in treating COPD 展开更多
关键词 Shengmai injection chronic obstructiv e pulmonary disease respiratory function
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Risk Factors for Postoperative Pulmonary Complications Following Posterior Spinal Fusion in Adolescent Scoliosis:A Retrospective Cohort Study 认领 引用
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作者 Jing Zhan Ai Hu +2 位作者 Huai-Yuan Wang Yue-Lun Zhang Wei-Yun Chen 《Chinese Medical Sciences Journal》 CAS CSCD 2026年第1期1-9,I0001,共9页
Objective Scoliosis is a prevalent spinal deformity that severely impacts the physical and psychological well being of adolescents and often requires surgical correction.This study aimed to investigate the risk factor... Objective Scoliosis is a prevalent spinal deformity that severely impacts the physical and psychological well being of adolescents and often requires surgical correction.This study aimed to investigate the risk factors for postoperative pulmonary complications(PPCs)following posterior spinal fusion in adolescent scoliosis,with a specific focus on evaluating the predictive value of preoperative forced vital capacity(FVC)and etiological classification.Methods This retrospective cohort study enrolled adolescents who underwent posterior spinal fusion for scoliosis correction at Peking Union Medical College Hospital between January 2018 and December 2022.The baseline demographic,clinical,and perioperative variables were collected.The primary endpoint was the occurrence of PPCs prior to hospital discharge.Univariate and multivariable binary logistic regression analyses were conducted to identify independent risk factors.Results A total of 1,234 patients were included,of whom 29(2.35%)developed PPCs and 1,205 did not.Univariate analysis revealed that 12 variables,including non-idiopathic scoliosis,a larger main thoracic curve,a decreased FVC%predicted,and increased perioperative blood transfusions,were significantly associated with PPCs(P<0.05).Multivariable logistic regression model showed that non-idiopathic scoliosis emerged as the sole independent risk factor for PPCs[adjusted odds ratio(OR)=5.478,95%confidence interval:2.017-19.148,P=0.002].Preoperative FVC%predicted(adjusted OR=0.993,P=0.497)and main thoracic curve(adjusted OR=1.002,P=0.736)did not demonstrate independent predictive value.Conclusions Non-idiopathic scoliosis,rather than preoperative pulmonary function or curve severity,is an independent risk factor for PPCs following posterior spinal fusion in adolescents.During perioperative respiratory risk assessment,particular emphasis should be placed on the etiological classification of these patients. 展开更多
关键词 scoliosis adolescent spinal fusion postoperative complications respiratory function tests risk factors
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