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Noninvasive interception of circulating leukocyte in vivo by optical tweezer array 认领 引用 被引量：1
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作者 Sisi Ge Jinhua Zhou Xunbin Wei 《Journal of Innovative Optical Health Sciences》 SCIE EI CSCD 2026年第1期56-69,共14页
The ability to noninvasively manipulate and isolate specific cell populations in vivo is critical for advancing real-time diagnostics,precision medicine,and immunological research.Here,we present a novel and broadly a... The ability to noninvasively manipulate and isolate specific cell populations in vivo is critical for advancing real-time diagnostics,precision medicine,and immunological research.Here,we present a novel and broadly applicable optical trapping system based on a custom-designed 2×3 optical tweezer array,which enables the real-time interception and manipulation of circulating leukocytes in live animals.By utilizing intrinsic velocity differences between leukocytes and red blood cells,the system achieves stable trapping of individual leukocytes in vessels 15-20μm in diameter and decelerates multiple cells in vessels greater than 20μm.Notably,it also enables the optical blockage of lymphatic vessels exceeding 50μm,a previously unreported capability.This label-free,noninvasive approach operates without repeated blood draws and is compatible with diverse vessel geometries and flow dynamics.The system offers a generalizable solution for in vivo cell extraction and analysis,paving the way for high-precision single-cell technologies in biomedical research and clinical translation. 展开更多
关键词 Leukocytes optical tweezer array in vivo interception
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Research on anti-active mainlobe interference methods for frequency diverse array radar 认领 引用
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作者 WANG Bo LI Yonglin +2 位作者 WANG Gang YANG Rennong ZHAO Yu 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2026年第2期455-466,共12页
In environments with complex electromagnetic characteristics,signals from active repeater mainlobe deception jamming are closely aligned with radar emissions,significantly impairing radar functionality.This paper expl... In environments with complex electromagnetic characteristics,signals from active repeater mainlobe deception jamming are closely aligned with radar emissions,significantly impairing radar functionality.This paper explores the efficacy of frequency diverse array(FDA)radar in combating active mainlobe jamming.Initially,the signal model for FDA multi-input multioutput(FDA-MIMO)radar is introduced.Building on this,a frequency offset optimization approach for FDA radar using the differential artificial bee colony(DEABC)algorithm is developed.Following this,the steepest descent linear minimum variance distortionless response beamforming algorithm is implemented in an FDA early warning radar to mitigate mainlobe jamming.Simulations are conducted to validate the effectiveness of the proposed strategies.The results from these simulations demonstrate that the methodologies can create a focused beam aimed at the target while effectively neutralizing jamming signals within the mainlobe area. 展开更多
关键词 frequency diverse array(FDA) phased array radar active jamming mainlobe jamming
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Optimization of the frequency offset increment of FDA-MIMO based on cuckoo search algorithm 认领 引用 被引量：1
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作者 WANG Bo ZHAO Yu +2 位作者 LI Yonglin YANG Rennong XUE Junjie 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2026年第1期157-170,共14页
Frequency diverse array multiple-input multiple-output(FDA-MIMO)radar has gained considerable research attention due to its ability to effectively counter active repeater deception jamming in complex electromagnetic e... Frequency diverse array multiple-input multiple-output(FDA-MIMO)radar has gained considerable research attention due to its ability to effectively counter active repeater deception jamming in complex electromagnetic environments.The effectiveness of interference suppression by FDA-MIMO is limited by the inherent range-angle coupling issue in the FDA beampattern.Existing literature primarily focuses on control methods for FDA-MIMO radar beam direction under the assumption of static beampatterns,with insufficient exploration of techniques for managing nonstationary beam directions.To address this gap,this paper initially introduces the FDA-MIMO signal model and the calculation formula for the FDA-MIMO array output using the minimum variance distortionless response(MVDR)beamformer.Building on this,the problem of determining the optimal frequency offset for the FDA is rephrased as a convex optimization problem,which is then resolved using the cuckoo search(CS)algorithm.Simulations confirm the effectiveness of the proposed approach,showing that the frequency offsets obtained through the CS algorithm can create a dot-shaped beam direction at the target location while effectively suppressing interference signals within the mainlobe. 展开更多
关键词 frequency diverse array multiple-input multiple-output(FDA-MIMO) convex optimization cuckoo search algorithm beampattern
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2025年美国FDA批准兽药汇总与统计分析 认领 引用
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作者 孙雷 沈昕 +5 位作者 段聪 王亦琳 叶妮 郭翱 杜雨 徐倩 《中国兽药杂志》 2026年第5期6-13,共8页
本文汇总了2025年美国FDA批准的兽药,并从批准途径、靶动物和适应证等方面进行统计分析,对部分兽药进行简要介绍,旨在为我国兽药研发和评审工作提供参考。
关键词 FDA 批准兽药 2025年 汇总 统计分析
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Accurate mode control based on inerter array of large unmanned underwater vehicle propulsion motor floating raft system 认领 引用
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作者 Yuehao Li Niaoqing Hu +4 位作者 Zhengyang Yin Yi Yang Xiaosong Lin Zhe Cheng Zuanbo Zhou 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2026年第4期166-194,共29页
Inerter is a basic two-terminal dynamic element.To explore the theory of inerter and obtain new mode control method of large unmanned underwater vehicle propulsion motor floating raft system,novel accurate mode contro... Inerter is a basic two-terminal dynamic element.To explore the theory of inerter and obtain new mode control method of large unmanned underwater vehicle propulsion motor floating raft system,novel accurate mode control based on inerter array is proposed.First,accurate mode control based on triangular inerter array is researched.Then,method of accurate mode control based on rectangular inerter array is explained.Then,accurate mode control based on cross inerter array is researched.Dynamic models and accurate mode control methods are verified by experiments.The percentage deviations between experimental and theoretical natural frequencies are within 12%.It is concluded that accurate mode control based on inerter array is effective.Triangular inerter array and rectangular inerter array with equal inertances and nonzero distances must change all points to change a mode.Isosceles triangular inerter array which contains zero distance and cross inerter array need to change two points to change a torsional mode.Inerter arrays with a centroid inerter can accurately change the translational mode. 展开更多
关键词 Inerter Inerter array Accurate mode control Natural frequency
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玻璃体内抗VEGF药物血栓栓塞不良事件风险:基于美国FDA不良事件报告系统的真实世界药物警戒研究 认领 引用
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作者 张英杰 陈耀升 贾雪松 《眼科新进展》 CAS CSCD 北大核心 2026年第8期642-646,共5页
目的基于美国FDA不良事件报告系统(FAERS)数据库,分析阿柏西普、布西珠单抗、法瑞西单抗及雷珠单抗四种玻璃体内抗血管内皮生长因子(VEGF)药物的栓塞不良事件特征及风险,为临床安全用药提供参考。方法提取2004年第1季度至2025年第4季度F... 目的基于美国FDA不良事件报告系统(FAERS)数据库,分析阿柏西普、布西珠单抗、法瑞西单抗及雷珠单抗四种玻璃体内抗血管内皮生长因子(VEGF)药物的栓塞不良事件特征及风险,为临床安全用药提供参考。方法提取2004年第1季度至2025年第4季度FAERS数据库中目标药物相关不良事件公开去标识化数据,筛选栓塞不良事件;采用报告比值比法与比例报告比值比法进行信号挖掘,分析事件特征及风险关联。结果共纳入四种药物不良事件报告58451例,栓塞不良事件6331例,其中阿柏西普占其总不良事件的8.67%、布西珠单抗占12.27%、法瑞西单抗占3.65%、雷珠单抗占14.93%。系统器官分类方面,雷珠单抗与阿柏西普主要累及神经系统、心脏及眼部,法瑞西单抗与布西珠单抗以眼部事件为主。栓塞不良事件中位发生时间由短至长依次为:布西珠单抗(50.0 d)、法瑞西单抗(68.4 d)、阿柏西普(93.8 d)、雷珠单抗(125.2 d);死亡比例由高至低依次为:雷珠单抗(10.54%)、阿柏西普(9.02%)、法瑞西单抗(8.26%)、布西珠单抗(2.54%)。结论布西珠单抗与阿柏西普眼内血管栓塞风险更高,阿柏西普及雷珠单抗兼具心脑血管栓塞风险。临床应结合患者个体情况,加强眼部及心脑血管不良事件监测与风险评估。 展开更多
关键词 抗血管内皮生长因子药物 血栓栓塞不良事件 美国FDA不良事件报告系统 死亡 数据挖掘
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Albumin-based fluorescent sensor array for differentiating of tetracyclines through host-guest recognitions 认领 引用
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作者 Zhongyong Xu Jun Peng +3 位作者 Wenxing Zhang Lei Wang Xiongzhi Xiang Bin Liu 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第6期448-451,共4页
The overuse and improper disposal of tetracyclines raise significant environmental and public health concerns due to their persistent ecotoxicological effects.However,there is still a lack of simple,readily available,... The overuse and improper disposal of tetracyclines raise significant environmental and public health concerns due to their persistent ecotoxicological effects.However,there is still a lack of simple,readily available,and effective method for simultaneously detecting multiple tetracyclines.Herein,we present a simple fluorescent sensor array for the detection and identification of multiple tetracyclines(including tetracycline,oxytetracycline,chlortetracycline,and doxycycline)based on host-guest recognitions between albumin(host)and tetracycline(guest).Upon entering the hydrophobic cavity of albumin,tetracycline exhibits a significant enhancement in its intrinsic fluorescence.The differential binding affinity of two albumins to four tetracyclines resulted in different fluorescent responses,creating distinct fluorescence patterns for each tetracycline.With the assistance of machine learning technique,including linear discriminant analysis(LDA)and hierarchical cluster analysis(HCA),this sensor array demonstrated the significant discrimination and classification capabilities for four common tetracyclines and their mixtures with 100%accuracy.Additionally,the array has been successfully applied to differentiate tetracyclines in real food samples.The spiked antibiotics in water sample were determined with a satisfactory recovery of 96.33%-106.5%.This work offers a simple but promising method for differentiating tetracycline antibiotics and presents a versatile strategy for sensor array design. 展开更多
关键词 Tetracyclines Fluorescent sensor array Albumin Host-guest Food samples
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A“breathable”3D lithium host with MnO2nanoflake array for long-lifespan anode-free lithium metal batteries 认领 引用
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作者 Jiaojiao Deng Haocheng Li +6 位作者 Fei Zheng Qingsong Weng Yu Bai Xiaoliang Yu Qianlin Zhang Qinghua Liang Baohua Li 《Chinese Chemical Letters》 SCIE CAS CSCD 2026年第3期722-726,共5页
The emerging anode-free lithium metal battery(AFLMB)is very promising for the next-generation electrochemical energy storage technology due to its remarkable high-energy density.However,the current development of AFLM... The emerging anode-free lithium metal battery(AFLMB)is very promising for the next-generation electrochemical energy storage technology due to its remarkable high-energy density.However,the current development of AFLMB is seriously hampered by the low Coulombic efficiency and limited lifespan caused mainly by the uncontrolled dendritic lithium growth and significant volume change during Li plating/stripping on the traditional current collector.Here,we report the design of a“breathable”threedimensional(3D)lithium host with MnO2nanoflake array for long-lifespan AFLMB.Specifically,a dense MnO2nanoflake array stretchably grown on carbon cloth by an easy solution dipping method is constructed as a 3D current collector for AFLMBs.Both experimental and theoretical studies underlined that the Li2O/Mn nanoflake arrays produced spontaneously upon the initial lithiation can effectively guide uniform lithium nucleation and growth.Moreover,this unique 3D hierarchical structure expands/shrinks along with the lithium plating/stripping,accommodating the large volume expansion/shrinkage over the subsequent charge/discharge processes.As such,a dendrite-free lithium structure was achieved even at a high capacity of 10 m Ah/cm2.More importantly,the as-constructed AFLMB with this current collector exhibits impressive cycling stability with 64%capacity retained after 200 cycles.This study offers new insights into constructing highly efficient 3D protective layers for metal anodes toward the practical feasibility of anode-free batteries. 展开更多
关键词 Lithium metal battery Anode free Nanoflake array Mechanical breathing Cycling stability
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Design and investigation of iontronic flexible pressure sensor based on microstructure array 认领 引用
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作者 Zhenzhen Shang Hairong Kou +2 位作者 Libo Yang Xiaoyong Zhang Yuhang Pang 《Nanotechnology and Precision Engineering》 EI CAS CSCD 2026年第1期44-51,共8页
Flexible pressure sensors are widely used in fields such as healthcare,owing to their simple preparation method,abundant raw materials,and high sensitivity.To solve the problems of low sensitivity and high noise impac... Flexible pressure sensors are widely used in fields such as healthcare,owing to their simple preparation method,abundant raw materials,and high sensitivity.To solve the problems of low sensitivity and high noise impact that arise with traditional capacitive pressure sensors,this paper proposes an electrical double layer microarray capacitive pressure sensor using silver nanowires(AgNW)and ionic liquids.AgNW/polyimide(PI)flexible electrodes and microarray-structured ionic liquids are utilized to obtain highly sensitive responses to changes in weak physiological signals.The microarray structure is a 20×20 quadrangular prism convex array.Experimental tests show that the sensor has high sensitivity(3.1202 kPa−1,0–800 kPa)and fast responseecovery times(100/100 ms).By flexibly attaching the sensor to the skin or a computer mouse,rapid and stable monitoring of micromovements such as facial muscles,vocalization,swallowing,finger joint activity,and mouse clicks can be achieved.The results obtained here are of value for the development of intelligent flexible electronics. 展开更多
关键词 Electronic skin Iontronic mechanism Flexible sensor Ionic dielectric layer Highly sensitive array
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An Optimal Projection Residual Method for Identifying the Number and Types of Underwater Acoustic Propagating Modes Using a Vertical Line Array 认领 引用
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作者 ZHANG Shuang ZHANG Yinquan +3 位作者 QIN Jinxing LI Zhenglin GUO Yonggang WU Shuanglin 《Journal of Ocean University of China》 SCIE CAS CSCD 2026年第3期776-786,共11页
The structural characteristics of underwater acoustic fields are governed by propagating modes.Underwater acoustic signal processing requires accurate identification of both the number and types of these modes,which a... The structural characteristics of underwater acoustic fields are governed by propagating modes.Underwater acoustic signal processing requires accurate identification of both the number and types of these modes,which also has significant potential applications in underwater target detection,underwater communication,and ocean environment inversion.For a vertical line array(VLA),the conventional singular value(SV)method can estimate the mode number in high signal-to-noise ratio(SNR)conditions,but it fails to discriminate modal types and suffers rapid performance degradation in practical low-SNR environments.To overcome these limitations,a novel optimal projection residual(OPR)method that simultaneously identifies the number and types of acoustic propagating modes in the acoustic field of a VLA was developed.Comprehensive numerical simulations and experimental data demonstrate two distinct advantages of the proposed OPR method compared to the conventional SV method:1)the OPR method enables more accurate estimation of the number of propagating modes,and 2)it can efficiently identify both the number and types of acoustic propagating modes. 展开更多
关键词 optimal projection residual singular value vertical line array acoustic propagating modes
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CONSTRUCTION OF ASYMMETRIC ORTHOGONAL ARRAYS WITH REPEATED ROWS 认领 引用
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作者 Shanqi PANG Ganyu SONG +1 位作者 Jing WANG Yan ZHU 《Acta Mathematica Scientia》 SCIE CSCD 2026年第4期1957-1978,共22页
Orthogonal arrays with repeated rows have significant applications in the domains of statistical experimental design and pure error estimation,quantum information and quantum communication,and scientific computing and... Orthogonal arrays with repeated rows have significant applications in the domains of statistical experimental design and pure error estimation,quantum information and quantum communication,and scientific computing and computer theory,among others.However,there are many unsolved problems on orthogonal arrays with repeated rows.This paper focuses on asymmetric orthogonal arrays.First,we find a bound for asymmetric orthogonal arrays of strength 2 with repeated rows.Second,based on this bound,optimal orthogonal arrays and m-optimal orthogonal arrays are defined.By using the orthogonal decomposition of projection matrices and the contractive replacement method,we construct many asymmetric orthogonal arrays of strength 2 with repeated rows including quite a few optimal and m-optimal ones.Finally,by employing the juxtaposition method and the expansive replacement method,asymmetric orthogonal arrays of general strength with repeated rows are obtained.Some selective new ROAs are tabulated for practical uses. 展开更多
关键词 orthogonal array with repeated rows optimal projection matrices replacement method juxtaposition
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3D printed high-temperature ceramic conformal array antenna:Design,analysis,manufacturing,and testing 认领 引用
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作者 Peng Li Ruibo Li +5 位作者 Zijiao Fan Jiujiu Han Guangda Ding Qunbiao Wang Wanye Xu Paolo Rocca 《Defence Technology（防务技术）》 SCIE EI CAS CSCD 2026年第1期340-353,共14页
In this study,the design,analysis,manufacturing,and testing of a 3D-printed conformal microstrip array antenna for high-temperature environments is presented.3D printing technology is used to fabricate a curved cerami... In this study,the design,analysis,manufacturing,and testing of a 3D-printed conformal microstrip array antenna for high-temperature environments is presented.3D printing technology is used to fabricate a curved ceramic substrate,and laser sintering and microdroplet spraying processes are used to add the conductive metal on the curved substrate.The problems of gain loss,bandwidth reduction,and frequency shift caused by high temperatures are addressed by using a proper antenna design,with parasitic patches,slots,and metal resonant cavities.The antenna prototype is characterized by the curved substrates and the conductive metals for the power dividers,the patch,and the ground plane;its performance is examined up to a temperature of 600℃in a muffle furnace and compared with the results from the numerical analysis.The results show that the antenna can effectively function at 600℃and even higher temperatures. 展开更多
关键词 Ceramic antenna Conformal array High-temperature environment 3D printing High gain and wide band
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Short-period dense linear array ambient noise tomography of shallow crustal structure across the Haichenghe fault zone,China 认领 引用
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作者 Mingruo Jiao Liang Wang +9 位作者 Hongyu Ni Haiyan Wang Lanshu Bai Shuo Liu Zhihong Zhang Zhenpeng Yang Zhengdong Cui Qingshan Sun Rui Qian Mengying Li 《Earthquake Science》 CAS CSCD 2026年第2期220-234,共15页
The Haicheng region,Liaoning,China,likely hosts a conjugate fault system comprising the NW-trending Haichenghe fault and NE-trending secondary faults.On February 4,1975,at 19:36 CST,an earthquake of MS7.3 and inten... The Haicheng region,Liaoning,China,likely hosts a conjugate fault system comprising the NW-trending Haichenghe fault and NE-trending secondary faults.On February 4,1975,at 19:36 CST,an earthquake of MS7.3 and intensity(MMI)IX hit the city of Haicheng,Liaoning,China.Although deep seismic profiling was previously conducted along the Haichenghe fault,the limited horizontal resolution in the shallow part prevented the recognition of kilometer-scale anomalies.The velocity structure characteristics of the Haichenghe fault and its NE-trending conjugate faults remain unclear.Using the extended range phase shift method,the high-resolution S-wave velocity structures are obtained by deploying a long,dense linear array of 55 short-period seismometers across the fault and NE-trending conjugate faults.The array length was 32 km and inter-station spacing was approximately 600 m,facilitating the collection of approximately 22 days of continuous waveform data.Employing the Extended Range Phase Shift(ERPS)method enabled the extraction of broadband 0.2–5 s Rayleigh wave phase velocity dispersion curves.The broadband dispersion data were used for inversion of the high-resolution S-wave velocity structure to a depth of 8 km from the surface.The velocity structure characteristics and seismicity of the Haichenghe fault and NE-trending conjugate faults were analyzed and compared with nearby fault gas measurements.Results show(1)shallow S-wave velocities show a low-high-low horizontal distribution,corresponding to basin-uplift-basin topography;(2)significant velocity contrasts occur across the Haichenghe fault:its SW segment(0–17 km)exhibits high velocities consistent with Paleoproterozoic crystalline basement(Pt1),while the NE segment(17–32 km)shows low velocities related to Yanshanian intrusions(γ5)and Quaternary sediments.NE-trending conjugate faults display sharp velocity gradients marking fracture locations,with all faults being near-vertical to~8 km depth;(3)seismicity at 1–6 km depth mainly clusters in high-velocity zones;at 6–8 km depth,it concentrates beneath the Haichenghe fault in low-velocity areas and along NE-trending faults;(4)the seismic activity characteristics and fault zone width of the Haicheng he fault reflected by velocity imaging results are basically consistent with those obtained by the fault gas measurement method. 展开更多
关键词 dense linear array ambient noise tomography extended range phase shift method S-wave velocity structure Haichenghe fault
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Solar array design and verification for Tianwen-2 认领 引用
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作者 WU Yuemin YU Jingjun +5 位作者 LI Xuli YIN Xingyue HAO Xiaoli ZHANG Qiming ZENG Fuming ZHANG He 《中国空间科学技术（中英文）》 CSCD 北大核心 2026年第3期181-191,共11页
Tianwen-2 is China's first mission for near-Earth asteroid sampling and main-belt comet exploration. After analyzing the orbital environment and operational requirement, a circular flexible solar wing configuratio... Tianwen-2 is China's first mission for near-Earth asteroid sampling and main-belt comet exploration. After analyzing the orbital environment and operational requirement, a circular flexible solar wing configuration is adopted, addressing key constraints including operation under low-intensity low-temperature(LILT) conditions, reliable stowage during launch, and long-term tension management. High-efficiency triple-junction GaAs solar cells are developed through bandgap engineering and edge passivation, achieving an average conversion efficiency >34% at 2.5 au. The blanket design uses a modular, mirror-symmetric layout with planarized circuits and lightweight backing to ensure reliable stowage. Thermal simulation and tension compensation are employed to manage internal stresses, while ultra-lightweight support structures and planar stress-relief interconnects maintain ribbon stresses below 80% of the fatigue limit. Simulation and ground testing confirm that the array meets the mission's power needs, with post-deployment verification validating its output performance and operational stability. 展开更多
关键词 Tianwen-2 deep space probe solar array flexible solar wing low-intensity low-temperature(LILT)
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Low-Frequency Ultrasonic Array Imaging of Interlayer Voids Hidden in Ballastless Track Structure of High-Speed Railway 认领 引用
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作者 Guopeng Fan Xuefeng Chen +1 位作者 Hao Liu Jiaqing Zheng 《Structural Durability & Health Monitoring》 EI 2026年第4期88-117,共30页
Low-frequency ultrasonic array is commonly used to detect interlayer voids located in high-speed railway ballastless track,which is a typical multilayer concrete bonded structure.The difficulty of detection lies in th... Low-frequency ultrasonic array is commonly used to detect interlayer voids located in high-speed railway ballastless track,which is a typical multilayer concrete bonded structure.The difficulty of detection lies in the fact that the total focusingmethod(TFM)based on a single fixed sound velocity model cannot adapt to the acoustic propagation characteristics of multilayer structures,which is prone to generating artifacts.In addition,the long duration of lowfrequency ultrasonic pulses is prone to causing significant deviations in defect localization.To address these issues,a theoretical model of the layered bonded structure is proposed.The acoustic wave propagation path and travel time calculation are clarified after combining the Fermat’s principle and Snell’s law,and the shortest path ray tracing(SPRT)is proposed,which achieves visual imaging of interlayer voids;The pulse peak delay(PPD)is applied to correct the travel time of low-frequency ultrasonic waves,and the shortest path ray tracing combined with pulse peak delay(PSPRT)is proposed,which significantly improves the localization accuracy of defects.Finally,by integrating the amplitude and phase information of scattered signals,the shortest path ray tracing based on pulse peak delay and sign coherence factor(PPSPRT)is constructed,which significantly enhances the SNR.The test results show that,compared with the conventional TFM,the proposed PPSPRT achieves average SNR improvements of 6.62 dB in numerical simulations and 14.30 dB in field tests,and reduces the average depth localization error of interlayer voids to merely 23.49%and 10.38%of that of TFM under corresponding test conditions,respectively.PPSPRT can provide important guidance for accurate imaging of interlayer voids. 展开更多
关键词 Low-frequency ultrasonic array interlayer voids bonded structure ray tracing localization accuracy
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Improved dynamic anti-resonance vibration isolator based on a Halbach array negative stiffness mechanism 认领 引用
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作者 Jialei DENG Xinhua LONG 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2026年第5期941-964,共24页
To concurrently achieve low-frequency vibration absorption and high-frequency vibration isolation in high-static-stiffness applications,this study proposes a hybrid passive vibration isolator that integrates a lever m... To concurrently achieve low-frequency vibration absorption and high-frequency vibration isolation in high-static-stiffness applications,this study proposes a hybrid passive vibration isolator that integrates a lever mechanism with a Halbach array negative stiffness mechanism.The lever mechanism reduces the natural frequency by increasing the system's effective mass and introduces an anti-resonance frequency.Additionally,the negative stiffness amplified by the lever counteracts the positive stiffness,leading to the substantial reduction in the dynamic stiffness with only a small amount of negative stiffness required.Both theoretical and experimental results indicate that the synergistic integration facilitates the broad isolation bandwidth and effective low-frequency absorption while keeping the added mass minimal and the negative stiffness low.The comparative analysis of several magnetic array configurations demonstrates that,when the isolator dimensions and added mass are held constant,the Halbach array configuration reduces both resonance and anti-resonance frequencies while preserving high-frequency transmissibility.The integrated strategy enables the development of a compact and lightweight isolator,providing an effective solution for low-frequency vibration suppression in scenarios where mass and space are limited. 展开更多
关键词 lever mechanism Halbach array low-frequency vibration absorption high-frequency vibration isolation high-static-stiffness application
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A double-layer reflective metasurface with increased polarization independent channels through rotating array 认领 引用
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作者 Bo YIN Xiaoliang LI Shubin WANG 《Optoelectronics Letters》 EI 2026年第6期337-343,共7页
The implementation of multifunctional metasurfaces through loading diodes has extremely high costs,while increasing the number of channels in the element through polarization multiplexing technology is limited.This pa... The implementation of multifunctional metasurfaces through loading diodes has extremely high costs,while increasing the number of channels in the element through polarization multiplexing technology is limited.This paper proposes a dual-band five-channel(DBFC)1-bit surface,which expands the polarization independent(PD)channels through rotating array.The polarization-independent metasurface element consists of three layers of metal,with the top layer comprising three rectangular patches oriented in the x-direction,the middle layer featuring a Jerusalem cross structure with accompanying resonators,and the bottom layer being a metal ground plane.The middle layer element can easily independently provide the required 1-bit reflection phases for two orthogonal polarizations in every frequency.The rectangular patches in the x-direction on the top layer do not contribute to the phase of y-polarization.By rotating the upper layer dielectric array 90°,the rectangular patches change to the y-direction.Under y-polarized illumination,the current distribution in the middle layer is shielded,providing a fifth set of polarization independent phases.The proposed 1-bit DBFC metasurface array has advantages in terms of structure and cost,while enhancing the utilization rate of the metasurface array.It has high application potential in microwave imaging,wireless power transmission,and other projects. 展开更多
关键词 Polarization independent channels Rotating array multifunctional metasurfaces loading diodes three rectangular patches Double layer reflective metasurface rotating arraythe polarization multiplexing technology
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FDA新政宣称“以新方法(NAMs)替代动物实验”,这是否意味实验动物学科将被取代? 认领 引用
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作者 赵建国 《中国比较医学杂志》 CAS 北大核心 2026年第3期F0002-F0002,共1页
FDA宣布计划逐步取消在单克隆抗体疗法和其他药物的研发中的动物实验要求,我觉得有两个考虑,一是新技术的发展日新月异,包括器官芯片、类器官和AI模型等在生物医药的研发中作用越来越大,但另外的考虑确实也是传统的实验动物在生物医药... FDA宣布计划逐步取消在单克隆抗体疗法和其他药物的研发中的动物实验要求,我觉得有两个考虑,一是新技术的发展日新月异,包括器官芯片、类器官和AI模型等在生物医药的研发中作用越来越大,但另外的考虑确实也是传统的实验动物在生物医药研发中并没有达到一个理想的支持作用。但在新技术还没有完全验证之前,取消药物研发中的动物实验要求是非常不负责任的。 展开更多
关键词 动物实验 新方法 替代 FDA 新政
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Pre‐Established Zincophilic Na2SiO3Decorated Array‐Like Channels to Regulate the Zn2þFlux and Interfacial Corrosion for Dendrite‐Free Zinc Anode 认领 引用
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作者 Xiangzhong Kong Jun Cao +6 位作者 Yanting Cai Yuyang Ding Zicong Wang Liya Rong Xi Chen Zhongmin Wan Jiande Lin 《Rare Metals》 SCIE EI CAS CSCD 2026年第6期536-548,共13页
Aqueous zinc‐ion batteries(AZIBs)have attracted increasing attention in energy storage owing to their high energy density,low redox potential,and cost‐effectiveness.Nevertheless,uncontrolled dendrite accumulation,ga... Aqueous zinc‐ion batteries(AZIBs)have attracted increasing attention in energy storage owing to their high energy density,low redox potential,and cost‐effectiveness.Nevertheless,uncontrolled dendrite accumulation,gas generation,and severe side‐reaction problems hinder the cycling lifespan,which prevents their commercial applications.Herein,array‐like porous channels decorated by Na2SiO3sites were in situ created on the diatomite layers by etching with NaOH(DH).DFT calculation results demonstrate that in situ formed Na2SiO3possesses improved Zn2+affinity.The negative 3D porous channels combined with zincophilic Na2SiO3sites provide a fast Zn2+transport pathway and facilitate the ion‐pair dissociation of ZnSO4,ensuring favorable Zn2+transfer kinetics and inhibited side reactions.Moreover,the ordered array‐like structure not only can exert a spatial confinement effect to suppress the 2D diffusion of Zn2+but also drive Zn metal preferential deposit toward the rigid microaligned channels and curb the formation of large‐scale zinc dendrites.Additionally,the hydrophobic diatomite protective layer can accelerate desolvation kinetics of Zn(H2O)62+and suppress the hydrogen evolution reactions.As a result,the DH‐modified Zn anode(DH@Zn)achieves a long cycle lifespan of 2500 h at 1 mA cm−2,much more than that of bare Zn(~100 h lifespan)in symmetrical cells.Besides,the DH@Zn//NH4V4O10(NVO)full cells demonstrate a high‐capacity retention of 93.3%after 1800 cycles at 5 A g−1.This work provides a promising strategy and new insights into the design of electrolyte‐anode interfacial protection. 展开更多
关键词 aqueous zinc ion batteries array‐like porous channels dendrite‐free Zn anode hydrophobic diatomite protective layer zincophilic Na2SiO3sites
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基于密度锥削阵的FDA-MIMO抗随队干扰方法 认领 引用
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作者 张晶 刘征 王博 《空天预警研究学报》 CSCD 2026年第3期210-215,共6页
针对随队干扰下传统相控阵存在主瓣畸变、基础频率分集阵列(FDA)波束多极值的问题,提出一种基于密度锥削阵(DTA)的频率分集阵列-多输入多输出(FDA-MIMO)随队干扰抑制方法.首先,将搭载正弦频控函数的DTA引入FDA体制,优化发射波束能量聚焦... 针对随队干扰下传统相控阵存在主瓣畸变、基础频率分集阵列(FDA)波束多极值的问题,提出一种基于密度锥削阵(DTA)的频率分集阵列-多输入多输出(FDA-MIMO)随队干扰抑制方法.首先,将搭载正弦频控函数的DTA引入FDA体制,优化发射波束能量聚焦;然后,提出牛顿-最速下降线性约束最小方差(NeWton-SD-LCMV)自适应波束形成算法,修正导向矢量失配.仿真结果表明,该方法角度维主瓣宽度减小了37.5%,距离维主瓣宽度减小了50%,旁瓣电平降低了7.3dB;在角度强耦合场景下输出信干噪比(SINR)达30.5dB,较基础FDA-MIMO提升11.9dB;2°指向误差下目标增益损失仅0.2dB,干扰零陷深度最深可达-36.8dB,可在距离-角度耦合场景下精准抑制随队干扰. 展开更多
关键词 随队干扰抑制 密度锥削阵 频率分集阵列-多输入多输出 自适应波束形成
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