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Primary School Science Problem-Solving Teaching:Teaching Misconceptions and Strategy Improvement 认领 引用
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作者 MAO Yuanyuan TANG Aibin 《US-China Education Review(A)》 2026年第1期30-35,共6页
Current Problem-Solving teaching in primary school science suffers from some misconceptions,such as“insufficient cultivation of problem awareness,lacking drive”,“insufficient deliberation in problem setting,lacking... Current Problem-Solving teaching in primary school science suffers from some misconceptions,such as“insufficient cultivation of problem awareness,lacking drive”,“insufficient deliberation in problem setting,lacking design”,“insufficient emphasis on the solving process,lacking effectiveness”,and“insufficient evaluation of solving results,lacking feedback”.To address these,this paper explores the“Four Emphases and Four Transformations”strategy for Problem-Solving teaching:First,emphasize connecting with life phenomena,transforming subject knowledge into practice;second,emphasize flexibly using questioning forms,rationalizing difficulty settings;third,emphasize providing differentiated guidance,autonomizing the solving process;fourth,emphasize monitoring the learning process,routinizing reflection and evaluation. 展开更多
关键词 problem-solving primary school science four emphases and four transformations
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Novel therapeutic strategies for osteoarthritis:from mechanistic insights to precision medicine 认领 引用
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作者 Muhammad Umar Ziling Wang +4 位作者 Jingwen Li Zhen Li Gang Li Liping Tong Di Chen 《Bone Research》 SCIE CAS CSCD 2026年第3期723-741,共19页
Osteoarthritis(OA)is a prevalent chronic degenerative joint disease that significantly impacts the quality of life for over 500 million individuals affected.OA is increasingly recognized as a whole-joint disorder char... Osteoarthritis(OA)is a prevalent chronic degenerative joint disease that significantly impacts the quality of life for over 500 million individuals affected.OA is increasingly recognized as a whole-joint disorder characterized by complex biochemical and cellular changes across various joint tissues.However,traditional approaches such as nonsteroidal anti-inflammatory drugs(NSAIDs)and corticosteroids often fall short in halting disease progression or restoring joint function.Thereby,recent innovations in OA management are focused on underlying pathophysiology,driving the development of regenerative therapies,targeted antiinflammatory agents and senolytic or senomorphic approaches.Accordingly,this paper reviews current progress in these areas by integrating evidence from clinical and pre-clinical studies to clarify therapeutic limitations,unresolved mechanistic and phenotypic gaps and the emerging strategies required to advance disease-modifying therapy in OA.It further outlines pathways toward precision,phenotype-aligned interventions,an integration that current literature has not yet consolidated. 展开更多
关键词 targeted anti inflammatory agents biochemical cellular changes osteoarthritis chronic degenerative joint disease mechanistic insights regenerative therapies senolytic approaches precision medicine
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从Tech Insights公司被制裁看如何在激烈的国际竞争中合法使用技术情报 认领 引用
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作者 彭靖里 《竞争情报》 2026年第2期2-9,共8页
在中美科技竞争加剧和全球半导体产业战略博弈日益深化的背景下,技术情报活动的边界与风险已成为国际社会高度关注的议题。2025年,中国商务部将加拿大公司Tech Insights及其关联实体列入“不可靠实体清单”,标志着中国在半导体领域的反... 在中美科技竞争加剧和全球半导体产业战略博弈日益深化的背景下,技术情报活动的边界与风险已成为国际社会高度关注的议题。2025年,中国商务部将加拿大公司Tech Insights及其关联实体列入“不可靠实体清单”,标志着中国在半导体领域的反制措施由硬件与设备层面进一步延伸至技术情报与信息流动层面。此举引发了业界和学术界的广泛讨论。本文以Tech Insights被制裁事件为切入点,在梳理其业务模式与发展轨迹的基础上,探讨其在芯片逆向工程和技术情报服务方面的做法如何偏离国际公认的商业规范和职业道德,并分析这些做法的深层驱动因素及其对全球半导体创新生态系统及产业链和供应链安全带来的不利影响。文章指出,在大国竞争持续升级和技术民族主义势头渐起的背景下,传统上被视为商业中立的技术情报活动正愈加被工具化,并被纳入战略竞争框架。在这种情况下,仅依靠市场机制不足以化解安全与发展之间日益加剧的矛盾。本文着眼于如何在日趋激烈的国际竞争环境中合法合规地开展技术情报活动,提出有针对性的政策建议。文章强调,必须加快建立符合全球化趋势、以互利原则为基础的国家级竞争情报国际监管框架,这将为维护公平竞争和促进国际科技合作提供关键支持,具有重要的现实意义和政策价值。 展开更多
关键词 Tech Insights 技术情报 国际竞争 合法使用 风险
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Genomic insights into the survival code of karst plants 认领 引用
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作者 Xiongfang Liu Yongpeng Ma 《Plant Diversity》 SCIE CAS CSCD 2026年第2期227-230,共4页
Karst landscapes are developed on soluble rocks(primarily limestone),covering about 10-15%of Earth’s ice-free land surface(Ford and Williams,2007).Their unique geological properties have given rise to complex,heterog... Karst landscapes are developed on soluble rocks(primarily limestone),covering about 10-15%of Earth’s ice-free land surface(Ford and Williams,2007).Their unique geological properties have given rise to complex,heterogeneous,and“island-like”habitats that,combined with periodic drought,high calcium,and lownutrient stresses,foster high species diversity and endemism(Clements et al.,2006;Hao et al.,2015;Oliver et al.,2017;Monro et al.,2018).These conditions make karst ecosystems ideal“natural laboratories”for studying speciation and adaptive evolution(Clements et al.,2006;Oliver et al.,2017). 展开更多
关键词 soluble rocks soluble rocks primarily karst ecosystems genomic insights survival code karst plants limestone ice free land surface
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An Empirical Study on the Reflective Feedback Model Based on Pedagogical Agents to Improve Students’ Problem-Solving Ability 认领 引用 被引量：1
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作者 Hui-Lin Zhang Jun-Jie Yan +4 位作者 Jing Liu Zhuo-Cen Zou Qun-Fang Zeng Yu-Lu Jin Jian-Nan Wu 《教育技术与创新》 2025年第1期66-75,共10页
This study constructs a reflective feedback model based on a pedagogical agent(PA)and explores its impact on students’problem-solving ability and cognitive load.A quasi-experimental design was used in the study,with ... This study constructs a reflective feedback model based on a pedagogical agent(PA)and explores its impact on students’problem-solving ability and cognitive load.A quasi-experimental design was used in the study,with 84 students from a middle school selected as the research subjects(44 in the experimental group and 40 in the control group).The experimental group used the reflective feedback model,while the control group used the factual feedback model.The results show that,compared with factual feedback,the reflective feedback model based on the pedagogical agent significantly improves students’problem-solving ability,especially at the action and thinking levels.In addition,this model effectively reduces students’cognitive load,especially in terms of internal and external load. 展开更多
关键词 pedagogical agent problem-solving ability reflective feedback
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基于国产Insight NM/CT Pro SPECT/CT建立正常骨骼标准化摄取值参考区间 认领 引用
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作者 李敏 王雪梅 +3 位作者 刘帆 高丽蕾 李杰 魏振恒 《中国医学影像学杂志》 CSCD 北大核心 2026年第5期595-601,共7页
目的基于国产Insight NM/CT Pro SPECT/CT设备建立正常骨骼标准化摄取值(SUV)参考值范围,并探讨影响SUV的相关因素。资料与方法前瞻性纳入2024年3月-2025年7月内蒙古医科大学附属医院初诊发现占位性病变筛查骨转移的219例患者资料,使用I... 目的基于国产Insight NM/CT Pro SPECT/CT设备建立正常骨骼标准化摄取值(SUV)参考值范围,并探讨影响SUV的相关因素。资料与方法前瞻性纳入2024年3月-2025年7月内蒙古医科大学附属医院初诊发现占位性病变筛查骨转移的219例患者资料,使用Insight NM/CT Pro SPECT/CT行骨显像,使用基于CT的人工智能分割自动提取各骨区感兴趣区,并计算最大、平均标准化摄取值(SUVmax、SUVmean),建立正常骨骼的SUV参考值范围,并分析性别、年龄、身高、体重、体重指数等因素对SUV的影响。结果各骨区SUV差异有统计学意义(H=1162.289、1278.004,P均0.05)。SUVmax和SUVmean与年龄呈负相关(r=-0.718~-0.162,P均<0.05),与体重(r=0.277~0.523)、体重指数(r=0.246~0.505)呈正相关(P均<0.05)。除肋骨、颈椎、胸椎、肱骨(r=-0.200~0.242,P均<0.05),其他各骨区和总骨区SUVmax、SUVmean均与身高无相关性。结论本研究基于国产Insight NM/CT Pro SPECT/CT骨定量技术获得正常骨骼SUV参考值范围,可为骨病变诊断及评估提供参考,为国产设备的推广应用提供依据。 展开更多
关键词 骨骼 单光子发射计算机断层摄影术 国产 Insight NM/CT Pro SPECT/CT 标准化摄取值 骨定量
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Problem-Solving模式在英语读后续写中的运用 认领 引用
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作者 郑越峥 《成长》 2025年第5期37-39,共3页
随着全球化进程的加速,英语作为国际交流语言的重要性无需赘述。在英语教学中,如何有效提高学生的语言综合运用能力,尤其是写作和问题解决能力,成为教育工作者关注的重点。读后续写是一种将阅读与写作紧密结合的新型题型,主要围绕人与... 随着全球化进程的加速,英语作为国际交流语言的重要性无需赘述。在英语教学中,如何有效提高学生的语言综合运用能力,尤其是写作和问题解决能力,成为教育工作者关注的重点。读后续写是一种将阅读与写作紧密结合的新型题型,主要围绕人与自然、人与社会、人与自我三大主题展开。这类题型不仅考查考生的语言综合运用能力,还考验其思维能力和书面表达能力。通过对所给文章进行续写,考生需要创造性地延伸故事情节,同时保持文章的逻辑性和连贯性。在续写故事中,故事不会平淡无奇,总要制造一些起伏情节来吸引读者,最终解决问题,因此Problem-Solving模式在续写中运用广泛。本文通过探讨Problem-Solving模式在英语读后续写中的运用,以期为英语教学提供新的思路和方法。 展开更多
关键词 英语读后续写 Problem-Solving模式 语言综合运用能力
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Visuospatial memory modulates insight and its predictive value for 6-year psychosis risk in clinical high-risk individuals 认领 引用
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作者 Li-Hua Xu Hui-Ru Cui +15 位作者 Yan-Yan Wei Xiao-Chen Tang Zhen-Ying Qian Dan Zhang Wen-Si Zheng Tian-Yuan Zhu Xiang-Fei Hong Jun-Juan Zhu Ye-Gang Hu Xu Liu Xiong Jiao Ying Qing Xiao-Chen Chen Ying-Ying Tang Tian-Hong Zhang Ji-Jun Wang 《World Journal of Psychiatry》 SCIE 2026年第5期156-170,共15页
BACKGROUND Impaired insight is a core feature of schizophrenia and an established predictor of psychosis in individuals at clinical high risk(CHR).However,the neurocognitive mechanisms underlying impaired insight in C... BACKGROUND Impaired insight is a core feature of schizophrenia and an established predictor of psychosis in individuals at clinical high risk(CHR).However,the neurocognitive mechanisms underlying impaired insight in CHR populations remain unclear.AIM To investigate the role of neurocognitive deficits in impaired insight and examine their combined influence on psychosis risk over a six-year follow-up.METHODS A total of 312 CHR individuals were assessed for insight using the G12 item of the Positive and Negative Syndrome Scale.Participants were categorized into the low-impairment insight group(n=151,G12 score<3)and the high-impairment insight group(n=161,G12 score≥3).Neurocognition was evaluated using the MATRICS Consensus Cognitive Battery.RESULTS Performance on the Brief Visuospatial Memory Test-Revised(BVMT-R)was the only cognitive domain differentiating the insight groups after controlling for positive symptoms.The effect of BVMT-R on insight was most pronounced at moderate symptom levels.Moreover,risk-curve analyses indicated that higher BVMT-R scores were associated with a reduced conversion risk linked to impaired insight.CONCLUSION Incorporating visuospatial memory assessment may improve the identification of those at greatest risk and inform targeted interventions aimed at enhancing insight and reducing conversion to psychosis. 展开更多
关键词 Marginal effects Conversion risk Clinical high risk for psychosis Visuospatial memory Impaired insight
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Chengdu’s Real Estate Market(2019-2024):An Integrated Framework for Data-Driven Insights and Policy Analysis 认领 引用
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作者 HU Xiao WU Jing +1 位作者 WANG Yan JIANG Xinyi 《Cultural and Religious Studies》 2026年第1期26-42,共17页
This study integrates multiple sources of data(transaction data,policy text,public opinion data)with visualization techniques(such as heat maps,time-series trend charts,3D building brochures)to construct an analysis f... This study integrates multiple sources of data(transaction data,policy text,public opinion data)with visualization techniques(such as heat maps,time-series trend charts,3D building brochures)to construct an analysis framework for the Chengdu real estate market.By using the Adaptive Neuro-Fuzzy Inference System(ANFIS)prediction model,spatial GIS(Geographic Information System analysis)analysis,and interactive dashboards,this study reveals market differentiation,policy impacts,and changes in demand structure,thereby providing decision support for the government,enterprises,and homebuyers. 展开更多
关键词 Chengdu City real estate market data-driven insights policy analysis
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Genomic insights into the domestication and genetic basis of yield in papaya 认领 引用 被引量：3
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作者 Min Yang Xiangdong Kong +6 位作者 Chenping Zhou Ruibin Kuang Xiaming Wu Chuanhe Liu Han He Ze Xu Yuerong Wei 《Horticulture Research》 SCIE CSCD 2025年第5期337-351,共15页
Papaya(Carica papaya L.)is an important tropical and subtropical fruit crop,and understanding its genome is essential for breeding.In this study,we assembled a high-quality genome of 344.17 Mb for the newly cultivated... Papaya(Carica papaya L.)is an important tropical and subtropical fruit crop,and understanding its genome is essential for breeding.In this study,we assembled a high-quality genome of 344.17 Mb for the newly cultivated papaya‘Zihui’,which contains 22250 proteincoding genes.By integrating 201 resequenced papaya genomes,we identified four distinct papaya groups and a 34 Mb genomic region with strong domestication selection signals.Within these regions,two key genes associated with papaya yield were discovered:Cp_zihui06549,encoding a leucine-rich receptor-like protein kinase,and Cp_zihui06768,encoding the accumulation of photosystem one 1(APO1)protein.Heterologous expression of Cp_zihui06549 in tomato confirmed that the total number of fruits in transgenic lines more than doubled compared to wild-type plants,resulting in a significant yield increase.Furthermore,we constructed a pan-genome of papaya and obtained a 77.41 Mb nonreference sequence containing 1543 genes.Within this pan-genome,2483 variable genes,we detected,including four genes annotated as the‘terpene synthase activity’Gene Ontology term,which were lost in cultivars during domestication.Finally,gene retention analyses were performed using gene presence and absence variation data and differentially expressed genes across various tissues and organs.This study provides valuable insights into the genes and loci associated with phenotypes and domestication processes,laying a solid foundation for future papaya breeding efforts. 展开更多
关键词 domestication selection genomic insights understanding its genome yield papaya integrating resequenced genetic basis domestication
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Autophagy regulation and function in axon regeneration:new insights from Caenorhabditis elegans 认领 引用 被引量：1
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作者 Su-Hyuk Ko Lizhen Chen 《Neural Regeneration Research》 SCIE CAS CSCD 2025年第12期3519-3520,共2页
Autophagy plays a crucial role in axon regeneration by maintaining cellular homeostasis and promoting the clearance of damaged organelles and proteins,which is essential for the growth and repair of axons.In response ... Autophagy plays a crucial role in axon regeneration by maintaining cellular homeostasis and promoting the clearance of damaged organelles and proteins,which is essential for the growth and repair of axons.In response to axonal injury,autophagy is upregulated to facilitate the removal of cellular debris and support the recycling of essential components needed for regeneration. 展开更多
关键词 homeostasis debris insight
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Role of academic self-efficacy in the relationship between self-directed learning readiness and problem-solving ability among nursing students 认领 引用
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作者 Xiao-Hong Zhang Li-Na Meng +4 位作者 Hui-Hui Liu Ru-Zhen Luo Chun-Mei Zhang Pei-Pei Zhang Yan-Hui Liu 《Frontiers of Nursing》 2018年第1期75-81,共7页
Objective: Problem-solving should be a fundamental component of nursing education because It is a core ability for professional nurses. For more effective learning, nursing students must understand the relationship be... Objective: Problem-solving should be a fundamental component of nursing education because It is a core ability for professional nurses. For more effective learning, nursing students must understand the relationship between self-directed learning readiness and problem-solving ability. The aim of this study was to investigate the relationships among self-directed learning readiness, problemsolving ability, and academic self-efficacy among undergraduate nursing students.Methods: From November to December 2016, research was conducted among 500 nursing undergraduate students in Tianjin, China,using a self-directed learning readiness scale, an academic self-efficacy scale, a questionnaire related to problem-solving, and selfdesigned demographics. The response rate was 85.8%.Results: For Chinese nursing students, self-directed learning readiness and academic self-efficacy reached a medium-to-high level,while problem-solving abilities were at a low level. There were significant positive correlations among the students' self-directed learning readiness, academic self-efficacy, and problem-solving ability. Furthermore, academic self-efficacy demonstrated a mediating effect on the relationship between the students' self-directed learning readiness and problem-solving ability.Conclusions: To enhance students' problem-solving ability, nursing educators should pay more attention to the positive impact of self-directed learning readiness and self-efficacy in nursing students' education. 展开更多
关键词 self-directed learning readiness problem-solving ability academic self-efficacy nursing undergraduates nursing students cross-sectional survey
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Molecular insights into TT2-type MYB regulators illuminate the complexity of floral flavonoids biosynthesis in Freesia hybrida 认领 引用 被引量：1
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作者 Xiaotong Shan Deyu Zhuang +10 位作者 Ruifang Gao Meng Qiu Liudi Zhou Jia Zhang Yanan Wang Qi Zhang Niu Zhai Guoyun Xu Li Wang Yueqing Li Xiang Gao 《Horticulture Research》 SCIE CSCD 2025年第3期67-79,共13页
Proanthocyanidins(PAs),anthocyanins,and flavonols are key flavonoids that play diverse roles in plant physiology and human health.Despite originating from a shared biosynthetic pathway,the regulatory mechanisms of PA ... Proanthocyanidins(PAs),anthocyanins,and flavonols are key flavonoids that play diverse roles in plant physiology and human health.Despite originating from a shared biosynthetic pathway,the regulatory mechanisms of PA biosynthesis and the cooperative regulation of different kinds of flavonoids remain elusive,particularly in flower tissues or organs.Here,we elucidated the regulatory network governing PA biosynthesis in Freesia hybrida‘Red River®’by characterizing four TT2-type MYB transcription factors,designated FhMYBPAs.Phylogenetic analysis,subcellular localization,and transactivation assays predicted their roles as PA-related activators.Pearson correlation analysis revealed significant correlations between FhMYBPAs and PA accumulation in various floral tissues and development stages.Functional studies demonstrated that FhMYBPAs activated PA biosynthesis by directly binding to the promoters of target genes,which can be enhanced by FhTT8L.Additionally,a hierarchical and feedback regulatory model involving FhTTG1,FhMYB27,and FhMYBx was proposed for PA biosynthesis.Furthermore,comparative analysis of flavonoid-related MYB factors involving FhPAP1,FhMYB5,FhMYBF1,and FhMYB21L2 highlighted their roles in regulating PA,anthocyanin,and flavonol biosynthesis,with some exhibiting versatile regulations.Overall,our findings provide insights into the spatio-temporal regulation of flavonoids in flowers and expand our understanding of MYB-mediated transcriptional regulation of specialized metabolites in plants. 展开更多
关键词 cooperative regulation regulatory network molecular insights floral flavonoids biosynthesis proanthocyanidins freesia hybrida red tt type myb regulators freesia hybrida
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Improved chromosome-level donkey(Equus asinus)genome provides insights into genome and chromosome evolution 认领 引用
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作者 Ge Yang Mian Gong +5 位作者 Qi-Meng Yang Yi-Dan Li Halima Jafari Chu-Zhao Lei Yu Jiang Rui-Hua Dang 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2025年第2期269-272,共4页
The donkey is an important livestock species that can provide milk,meat,and skin and belongs to the family Equus.The first genome of a male donkey was sequenced and de novo assembled using a whole-genome shotgun strat... The donkey is an important livestock species that can provide milk,meat,and skin and belongs to the family Equus.The first genome of a male donkey was sequenced and de novo assembled using a whole-genome shotgun strategy(Huang et al.,2015).Subsequently,the donkey genome showed greater improvement in continuity and chromosome length than a previous assembly(Renaud et al.,2018). 展开更多
关键词 insight belongs
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Mechanistic Insights into Electrocatalytic Urea Oxidation Reaction Through in situ Characterizations 认领 引用
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作者 Suzhen Bai Yi Zeng +3 位作者 Zhengshan Tian Kesheng Cao Xingwu Li Haoqi Wang 《化学进展》 SCIE CAS CSCD 北大核心 2025年第12期1769-1791,共23页
The electrocatalytic urea oxidation reaction(UOR)has emerged as an energy-efficient alternative to the traditional oxygen evolution reaction for hydrogen production,with mechanistic understanding being critical for th... The electrocatalytic urea oxidation reaction(UOR)has emerged as an energy-efficient alternative to the traditional oxygen evolution reaction for hydrogen production,with mechanistic understanding being critical for the rational design of catalysts.This review systematically summarizes recent advances in in situ characterization techniques for elucidating the dynamic reaction mechanisms of UOR.Studies reveal that phase transitions,valence state migration,and electronic structure evolution of catalysts under operational conditions are key factors governing activity and stability.Techniques such as in situ X-ray diffraction,X-ray absorption spectroscopy,Raman spectroscopy,and Fourier-transform infrared spectroscopy enable real-time monitoring of catalyst reconstruction,intermediate evolution,and interfacial adsorption behavior,overcoming the environmental deviations inherent in conventional ex situ characterization.When combined with theoretical calculations,these methods provide direct evidence for identifying active-site configurations,reaction pathways,and rate-determining steps.In addition,special emphasis is placed on multimodal in situ strategies for deciphering synergistic effects in nickel-based catalysts,while current challenges,including non-alkaline systems,real wastewater environments,and multi-metal cooperation mechanisms,are critically discussed.Future research should focus on developing novel in situ approaches for complex systems and establishing a mutually reinforcing framework integrating theoretical prediction and experimental validation,thereby advancing UOR catalyst design from empirical exploration to mechanism-guided optimization. 展开更多
关键词 urea oxidation reaction mechanistic insight in-situ characterizations active sites dynamic evolution
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Emerging insights into the function of very long chain fatty acids at cerebellar synapses 认领 引用
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作者 Martin-Paul Agbaga Mohiuddin Ahmad 《Neural Regeneration Research》 SCIE CAS CSCD 2025年第6期1709-1710,共2页
Very long chain-saturated and-polyunsaturated fatty acids(VLC-SFA and VLC-PUFA, respectively) are a functionally important class of fatty acids containing 28 carbons or more in their acyl chain. They are synthesized b... Very long chain-saturated and-polyunsaturated fatty acids(VLC-SFA and VLC-PUFA, respectively) are a functionally important class of fatty acids containing 28 carbons or more in their acyl chain. They are synthesized by the elongation of very long fatty acids-4(ELOVL4) enzyme, expressed mainly in the brain, retina, skin, testes, and meibomian gland, where these fatty acids are found(Agbaga et al., 2008). Further, these organs exhibit tissuespecific VLC-PUFA and VLC-SFA biosynthesis and incorporation into complex lipids for specific functions. In the brain, skin, and Meibomian glands, the ELOVL4 mainly makes VLC-SFA, which are incorporated into complex sphingolipids. In the retina, the ELOVL4 makes VLC-PUFA that are incorporated into phosphatidylcholine, that are critical for visual function, while in testes and sperm, the VLC-PUFA are incorporated into sphingolipids that are critical for fertility(Yeboah et al., 2021). 展开更多
关键词 functions function insight
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Genomic insights into the absence of root nodule formation and nitrogen fixation in Zenia insignis 认领 引用
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作者 Hang Yu Yongbin Lu +4 位作者 Chao Zhang Wenyuan Yang Hongjiang Xie Huiru Liu Haifeng Wang 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2025年第6期860-863,共4页
Symbiotic nitrogen fixation in members of the Fabaceae family is highly efficient and beneficial for global agriculture,but not all species in this family form root nodules with rhizobial bacteria.Nodulation mainly oc... Symbiotic nitrogen fixation in members of the Fabaceae family is highly efficient and beneficial for global agriculture,but not all species in this family form root nodules with rhizobial bacteria.Nodulation mainly occurs in plants belonging to the Papilionoideae and Caesalpinioideae subfamilies(Tederso0 et al.,2018;van Velzen et al.,2019).Nodulation mechanisms in Fabaceae are well studied(Yang et al.,2022),and genomic comparisons of nodulating and non-nodulating host species can provide valuable insights into the evolutionary and genetic basis of this key process. 展开更多
关键词 nitrogen fixation genomic insights rhizobial bacterianodulation symbiotic nitrogen fixation root nodule formation Zenia insignis genomic comparisons Fabaceae
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Making bridges between preclinical and clinical insights into age-related cognitive decline 认领 引用 被引量：2
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作者 David VC Brito Clévio Nóbrega 《Neural Regeneration Research》 SCIE CAS CSCD 2025年第8期2321-2322,共2页
With people living longer,the societal impact of age-related cognitive decline is becoming more pronounced(Crimmins,2015).Thus,it is increasingly important to comprehend the cognitive shifts linked to aging-whether th... With people living longer,the societal impact of age-related cognitive decline is becoming more pronounced(Crimmins,2015).Thus,it is increasingly important to comprehend the cognitive shifts linked to aging-whether they are physiological or pathological. 展开更多
关键词 bridges becoming insight
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Genomic insights into deleterious mutations and their impact on agronomic traits during pear domestication 认领 引用 被引量：2
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作者 Xiang Zhang Bobo Song +10 位作者 Shuai Du Shiqiang Zhang Yuexing Ren Cheng Xue Shaozhuo Xu Pengfei Zheng Shulin Chen Zhiwen Qiao Jiahao Liu Wei Wei Jun Wu 《Horticulture Research》 SCIE CSCD 2025年第9期76-90,共15页
The pear(Pyrus spp.),a perennial fruit tree,is subjected to genetic alterations over decades or even centuries to adapt to complex climatic and cultivation conditions.Genome-wide studies of deleterious mutations remai... The pear(Pyrus spp.),a perennial fruit tree,is subjected to genetic alterations over decades or even centuries to adapt to complex climatic and cultivation conditions.Genome-wide studies of deleterious mutations remain limited in perennial fruit trees,particularly regarding the effects of domestication on deleterious mutations.In this study,232 pear accessions were resequenced,and 9909773 single-nucleotide polymorphisms(SNPs),and 139335 deleterious mutation sites,were identified genome wide.A higher proportion of deleterious mutations in coding regions(1.4%)were observed in the pear genome than annual crops.During domestication,a reduction in deleterious mutations in Pyrus pyrifolia/P.bretschneideri was found to be associated with their decreases in selective sweep regions.Conversely,an increase in the number of deleterious mutations in P.communis was observed,which may be related to a higher occurrence within selective sweep regions.In P.ussuriensis,an overall increasing trend in deleterious mutations was identified,which was determined to be unrelated to domestication or gene introgression but instead linked to its relatively high heterozygosity.Differential deleterious mutation genes were identified during the domestication process.Among these,the PyMYC2 gene,associated with stone cell synthesis,was identified through GWAS,overexpression of PyMYC2 in pear callus significantly promoter lignin biosynthesis,PyMYC2 contains three nonsynonymous deleterious mutations that were selected during the domestication of Asian pears.This research provides new insights into developing future breeding strategies aimed at improving agronomic traits and offers a framework for studying deleterious mutation patterns in the domestication of perennial fruit trees. 展开更多
关键词 agronomic traits genomic insights selective sweep regions single nucleotide polymorphisms deleterious mutations pear domestication genetic alterations higher proportio
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Enhancing the Problem-Solving Skills of Vocational Students Through Skills Competition 认领 引用 被引量：4
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作者 Shang Wang Fei Peng Mengjie Li 《Journal of Contemporary Educational Research》 2022年第12期9-15,共7页
Unlike general education,vocational education aims to nurture skilled people for various sectors in the society.The development of students’problem analysis and problem-solving skills is crucial.As an important part ... Unlike general education,vocational education aims to nurture skilled people for various sectors in the society.The development of students’problem analysis and problem-solving skills is crucial.As an important part of the vocational education system,skills competitions are considered a“booster”for improving the quality of teaching in vocational institutions.This paper examines the problem-solving skills of students in preparation for skills competition.First of all,we introduce China’s education policies and conduct a review of early scholars’views,followed by a discussion on the specific problems faced in the design of the entry for skills competition and an exploration of the process of enhancing students’problem-solving skills around these problems;we then propose several suggestions for vocational institutions to enhance their participation in skills competitions.Skills competitions provide a“special stage”for students in vocational institutions to show their abilities.The question of how this“stage”can be utilized to better improve students’abilities is worth exploring in different fields. 展开更多
关键词 Skills competition Problem-solving skills Vocational students Vocational colleges
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