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Impact of Early Shoulder Joint Functional Exercise Program on Quality of Life of Survivors after Modified Radical Mastectomy 认领 引用
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作者 Tiantian Sun Mary Ann Bayani 《Journal of Clinical and Nursing Research》 2026年第3期349-362,共14页
This study aimed to evaluate the effects of an early shoulder joint functional exercise program on shoulder joint function and quality of life among breast cancer survivors who underwent modified radical mastectomy.Br... This study aimed to evaluate the effects of an early shoulder joint functional exercise program on shoulder joint function and quality of life among breast cancer survivors who underwent modified radical mastectomy.Breast cancer remains the most prevalent malignancy among women worldwide.With advances in early detection and comprehensive treatment,survival rates among breast cancer survivors have markedly improved.Consequently,the focus of postoperative care has shifted from disease control to long-term functional recovery and quality of life enhancement.However,shoulder joint dysfunction following modified radical mastectomy(MRM)remains a common and debilitating complication,significantly affecting upper limb function,daily activities,and overall quality of life.Although early shoulder joint functional exercises have been reported to be beneficial,their systematic integration into routine postoperative nursing care and their effects on both shoulder function and quality of life require further empirical investigation.A quantitative,quasi-experimental,non-equivalent control group design was employed.Sixty female breast cancer survivors who underwent unilateral MRM were recruited from a tertiary hospital in Shandong Province,China,and were allocated into an experimental group(n=30)and a control group(n=30)using sequential recruitment and sealed draw assignment.The experimental group received a structured,phase-based early shoulder joint functional exercise program beginning 1-3 days postoperatively,while the control group received routine postoperative functional exercise guidance.Shoulder joint function was assessed using the Constant-Murley Score(CMS)at baseline(preoperative),postoperative day 10,and postoperative day 30.Quality of life was measured using the Functional Assessment of Cancer Therapy-Breast(FACT-B)at postoperative day 30.Data were analyzed using descriptive statistics,independent and paired t-tests,and correlation analysis.Baseline comparisons revealed no statistically significant differences in demographic characteristics or shoulder function scores between the experimental and control groups of breast cancer survivors(p>0.05),indicating that the two groups were well-matched at the outset of the study.Following the intervention,shoulder function improvement in the experimental group was significantly greater than that in the control group.For instance,assessments using the Constant-Murley Shoulder Score(CMS)demonstrated that the experimental group exhibited statistically significant increases in shoulder function scores at both postoperative day 10 and day 30 compared to baseline levels(p<0.05),with a consistent upward trend.In contrast,although the control group also showed improvement at the same time points,the extent of improvement was markedly smaller.Intergroup comparisons further confirmed that CMS scores in the experimental group were significantly higher than those in the control group at both postoperative day 10 and day 30(p<0.05).With respect to quality of life,as evaluated by the Functional Assessment of Cancer Therapy-Breast(FACT-B)scale,the experimental group exhibited significantly higher total quality-of-life scores than the control group at postoperative day 30(p<0.05).Improvements were particularly notable in the physical well-being and functional well-being domains.Further correlation analysis indicated a significant positive relationship between shoulder function scores and overall quality-of-life scores among breast cancer survivors who received early shoulder rehabilitation interventions(p<0.05).This suggests that greater improvement in shoulder function is associated with better self-perceived quality of life in this population.Early shoulder joint functional exercise significantly improved shoulder joint function and quality of life among breast cancer survivors after modified radical mastectomy.The findings support the systematic incorporation of structured early shoulder joint functional exercises into routine postoperative nursing care to promote functional recovery and enhance overall quality of life. 展开更多
关键词 Breast cancer survivors Modified radical mastectomy Early shoulder joint functional exercise Shoulder joint function Quality of life Nursing intervention
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Clinical Investigation of Shoulder Joint Function and Pain Alleviation in Patients with Rotator Cuff Injuries via Structured Phased Rehabilitation Training 认领 引用
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作者 Yujie CHEN Chunming MA 《Medicinal Plant》 2026年第1期54-56,60,共3页
[Objectives]To investigate the clinical effects of implementing structured phased rehabilitation training,in addition to conventional rehabilitation,on shoulder joint function and pain alleviation in patients with rot... [Objectives]To investigate the clinical effects of implementing structured phased rehabilitation training,in addition to conventional rehabilitation,on shoulder joint function and pain alleviation in patients with rotator cuff injuries managed conservatively.[Methods]Eighty patients diagnosed with rotator cuff injury were selected and randomly assigned to either the control group or the experimental group,each comprising 40 individuals.The control group received conventional rehabilitation treatment,whereas the experimental group underwent phased rehabilitation training in addition to the conventional treatment for 6 weeks.Assessments were conducted prior to treatment,6 weeks following treatment,and 8 weeks after the completion of treatment(follow-up period).The visual analogue scale(VAS)was employed to evaluate pain intensity,the Constant-Murley score was utilized to assess shoulder joint function,and the shoulder joint range of motion was measured.[Results]Prior to treatment,no statistically significant differences were observed between the two patient groups across all measured indicators(P>0.05).Following 6 weeks of treatment and throughout the follow-up period,both groups exhibited significant reductions in VAS scores compared to baseline measurements,alongside improvements in Constant-Murley scores and shoulder joint range of motion(P<0.05).Furthermore,the magnitude of improvement in the experimental group was significantly greater than that in the control group(P<0.05).[Conclusions]Phased rehabilitation training can enhance shoulder joint function and alleviate pain in patients with rotator cuff injuries beyond the effects of conventional rehabilitation treatment,demonstrating notable clinical application value. 展开更多
关键词 Rotator cuff injury Phased rehabilitation training Shoulder joint function Pain Randomized controlled trial
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Evaluation of Task-Oriented Training Combined with Lower Limb Rehabilitation Robot on Improvement of Motor Function and Ankle Joint Function in Stroke Patients with Hemiplegia 认领 引用 被引量：1
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作者 Xingjun Shi 《Journal of Clinical and Nursing Research》 2025年第8期332-338,共7页
Objective:To evaluate the effect of task-oriented training combined with a lower limb rehabilitation robot on improving motor function and ankle joint function in stroke patients with hemiplegia.Methods:Sixty-three st... Objective:To evaluate the effect of task-oriented training combined with a lower limb rehabilitation robot on improving motor function and ankle joint function in stroke patients with hemiplegia.Methods:Sixty-three stroke patients with hemiplegia admitted to our hospital from January 2022 to June 2024 were randomly divided into observation group(32 cases)and control group(31 cases)using the envelope method.The control group received task-oriented training,while the observation group received additional lower limb rehabilitation robot training.The motor function(Fugl-Meyer Assessment of Lower Extremity,FMA-LE)and ankle joint function(Active Dorsiflexion Range of Motion,DF AROM)were compared between the two groups.Results:After treatment,the levels of FMA-LE and DF AROM in both groups increased significantly,and the improvement in each index in the observation group was better than that in the control group(P<0.05).Conclusion:The combination of task-oriented training and lower limb rehabilitation robot training can more effectively improve the overall motor function of the lower limbs and the active dorsiflexion ability of the ankle joint in stroke patients with hemiplegia. 展开更多
关键词 Stroke Hemiplegia Task-oriented training Lower limb rehabilitation robot Motor function Ankle joint function
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Effect of Artificial Hip Replacement Surgery on the Treatment of Intertrochanteric Femur Fractures in Elderly Patients and Its Impact on Hip Joint Function and Quality of Life 认领 引用 被引量：1
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作者 Yong Qin Jianfei Xu +1 位作者 Dongqian Feng Bin Zhang 《Journal of Clinical and Nursing Research》 2025年第1期88-93,共6页
Objective:To evaluate the treatment effect of total hip arthroplasty(THA)for intertrochanteric femur fractures(IFF)in elderly patients.Methods:Thirty-two elderly patients with IFF admitted to the hospital from August ... Objective:To evaluate the treatment effect of total hip arthroplasty(THA)for intertrochanteric femur fractures(IFF)in elderly patients.Methods:Thirty-two elderly patients with IFF admitted to the hospital from August 2021 to August 2024 were selected and randomly divided into two groups using a random number table.The experimental group(16 patients)underwent THA surgery,while the control group(16 patients)underwent proximal femoral nail antirotation(PFNA)surgery.Hip joint function and quality of life indicators were compared between the two groups.Results:Before surgery,there was no significant difference in hip joint function and quality of life scores between the two groups(P>0.05).However,at six months postoperatively,the experimental group had higher hip joint function and quality of life scores compared to the control group(P0.05).Conclusion:THA can improve the clinical efficacy of elderly patients with IFF,minimize postoperative complications,effectively restore hip joint function,and optimize postoperative quality of life. 展开更多
关键词 Artificial hip replacement surgery Intertrochanteric femur fractures Elderly patients Hip joint function Quality of life
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Meta-analysis and trial sequential analysis on blood uric acid and joint function in gouty arthritis treated with fire needling therapy in comparison with western medication 认领 引用 被引量：10
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作者 Kai-feng DENG Liang-huizhi LI +8 位作者 Ting-zhen PAN Heng NING Hui-ling LU Yuan-xi HUANG Xue LI Xiao-hua YOU Dan-meng ZHU Ying ZHU Ri-lan CHEN 《World Journal of Acupuncture-Moxibustion》 CAS CSCD 2022年第1期49-60,共12页
Objective:To conduct the meta-analysis and trial sequential analysis(TSA) on clinical trials of fire needling therapy in treatment of gouty arthritis and review systematically the clinical therapeutic effect of fire n... Objective:To conduct the meta-analysis and trial sequential analysis(TSA) on clinical trials of fire needling therapy in treatment of gouty arthritis and review systematically the clinical therapeutic effect of fire needling therapy on gouty arthritis so as to provide the medical evidences of the extensive application of this therapy in treatment of gouty arthritis.Methods:The relevant clinical trials of fire needling therapy for treatment of gouty arthritis were searched from China National knowledge Infrastructure,Wanfang Data Knowledge Service Platform,Chinese Science and Technology Journal Database,American Medical Online,Dutch Medical Literature Database and International Evidence-Based Medical library.Using Review Manager 5.3 software,the quality of the included trials was assessed and meta-analysis was performed.With TSA v0.9 software,the trial sequential analysis was conduced on the appropriate outcomes.Results:A total of 10 trials were included with 775 patients involved.The analysis results showed that compared with the western medication,the total effective rate(RR=1.14’95%CI [1.09,1.20]),the curative rate(RR=1.59’95%CI [1.33,1.89]),the reduced VAS score(MD=-1.44’ 95%CI [-1.93,-0.951]) and the reduced incidence of adverse reaction(RR=0.27’ 95% CI [0.09,0.76]) of the fire needling therapy were different significantly(all P <0.05).Regarding the reduction of blood uric acid(MD=-40.47’ 95%CI [-80.21,-0.72]) and the score of symptoms and physical signs(MD=-1.38’95% CI [-3.71,0.95]),the effect of fire needling therapy was similar to that of western medication group(both P≥0.05).The trial sequential analysis suggested that the result was reliable,in which,the total effective rate of fire needling therapy was much higher than the western medication.But,it was potentially a false-positive finding,in which,fire needling therapy was much more advantageous at reducing blood uric acid as compared with the western medication.Conclusion:Based on the analytic results,it can be determined that fire needling therapy,as an effective approach to the treatment of gouty arthritis,has a certain advantage as compared with western medication.Given the low overall quality of trials,it still needs high-quality clinical trial to verify the findings of this study results. 展开更多
关键词 Gouty arthritis Fire needle Blood uric acid Joint function Meta-analysis Trial sequential analysis
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Influence of stuck-needle technique on joint function and related inflammatory markers in patients with knee osteoarthritis:A randomized controlled trial 认领 引用 被引量：1
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作者 Kai-feng DENG Ying ZHU +2 位作者 Zi-long LIAO Guo-xiang WANG Ri-lan CHEN 《World Journal of Acupuncture-Moxibustion》 CAS CSCD 2020年第3期178-182,共5页
Objective:To observe the differences of clinical effect and influence on joint function and inflammatory markers in joint fluid between stuck-needle technique and regular acupuncture in patients with knee osteoarthrit... Objective:To observe the differences of clinical effect and influence on joint function and inflammatory markers in joint fluid between stuck-needle technique and regular acupuncture in patients with knee osteoarthritis.Methods:Seventy-two patients with knee osteoarthritis were randomly divided into a stuck-needle technique group and a regular acupuncture group,with 36 cases in each one.The selection of acupoints,retaining time of needles,and treatment course were all the same in both groups.The visual analog scale(VAS)score,Lequesne index score,and the content of related inflammatory indexes in joint fluid before and after treatment were observed,and the therapeutic effect were evaluated.Results:After treatment,the VAS scores,Lequesne index scores,interleukin-1 beta(IL-1β),and the tumor necrosis factor a(TNF-α)of the two groups were all lower than those before treatment(all P<0.05).After treatment,the VAS scores,Lequesne index scores,IL-1β,and TNF-αof the stuck-needle technique group were all lower than those of the regular acupuncture group(all P<0.05).The total effective rate of the stuck-needle technique group was 96.97%(32/33),higher than 93.75%(30/32)of the regular acupuncture group(P<0.05).Conclusion:Stuck-needle technique can effectively relieve the pain and improve the joint functions,being more effective than regular acupuncture for the treatment of knee osteoarthritis. 展开更多
关键词 Knee osteoarthritis(KOA) Stuck-needle technique Pain Joint function Randomized controlled trial(RCT)
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Progress of improvement of pain and joint function of knee osteoarthritis treated with thunder-fire moxibustion in the last five years 认领 引用
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作者 DENG Kai-feng MAO Wen-qian +1 位作者 ZHU Ying CHEN Ri-lan 《Journal of Hainan Medical University》 CAS 2022年第24期71-75,共5页
Objective:To summarize the clinical research of improvement of pain and joint function of knee osteoarthritis treated with thunder-fire moxibustion in the last five years,in order to provide more objective and scienti... Objective:To summarize the clinical research of improvement of pain and joint function of knee osteoarthritis treated with thunder-fire moxibustion in the last five years,in order to provide more objective and scientific theoretical basis for the clinical use of thunderfire moxibustion in the treatment of knee osteoarthritis.Methods:By using"thunder-fire moxibustion"and"knee osteoarthritis"as keywords,the clinical literature on the treatment of knee osteoarthritis mainly by thunder-fire moxibustion in the past 5 years in PubMed,CNKI,WF and VIP were analyzed.Results:Thunderfire moxibustion and its compound therapy,including internal use of traditional Chinese medicine,external use of traditional Chinese medicine,drug injection,physical therapy,acupuncture,heat sensitive moxibustion,pricking collaterals,acupoint application and ozone,could relieve pain,improve joint function,improve joint activity,improve patients daily life ability and have less adverse reactions.Conclusion:Thunder-fire moxibustion was a safe,non-invasive and effective treatment for knee osteoarthritis.However,further research is necessary due to the non-rigidity of the current clinical trial design. 展开更多
关键词 Thunder-fire moxibustion Osteoarthritis of knee Pain Joint function Research progress
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Study on Effect of Warm Acupuncture on Knee Osteoarthritis and Its Effect on Joint Function 认领 引用
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作者 SHI Chengzhu 《外文科技期刊数据库（文摘版）医药卫生》 2021年第9期960-962,共3页
Objective: to analyze the effect of warm acupuncture on knee osteoarthritis and its effect on joint function. Methods: a total of 60 patients with knee osteoarthritis in our hospital from February 2020 to November 202... Objective: to analyze the effect of warm acupuncture on knee osteoarthritis and its effect on joint function. Methods: a total of 60 patients with knee osteoarthritis in our hospital from February 2020 to November 2021 were selected, and they were randomly divided into 2 groups with 30 patients in each group according to the number table. Patients in the conventional group were given conventional treatment, and warm acupuncture was added to warm acupuncture in the assisted group. The improvement time of knee joint swelling, immobility, tingling and tenderness, morning stiffness, joint function score, lower limb walking function score, visual simulation score, serological inflammatory stress index, total effective rate and adverse reactions is compared between the two groups. Results: the improvement time of knee swelling, immobility, tingling and softness and morning stiffness in the warm acupuncture assisted group was shorter than that in the conventional group. After treatment, the visual simulation score and serological inflammatory stress index of patients were lower than that in the conventional group, and the joint function score and lower limb walking function score were higher than that in the conventional group, and the total effective rate was higher than that in the conventional group, P 0.05. Conclusion: on the basis of conventional treatment combined with warm acupuncture and moxibustion has definite therapeutic effect on knee osteoarthritis, which can improve clinical pain, walking inconvenience and other related symptoms of patients, shorten the time of symptom relief, reduce inflammatory stress, and further improve knee joint function and walking function, which is worthy of promotion and application. 展开更多
关键词 warm acupuncture knee osteoarthritis curative effect joint function impact
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Effect of Perioperative Nursing Intervention on Joint Function of Patients with Osteoarthritis after Operation 认领 引用
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作者 TONG Ting 《外文科技期刊数据库（文摘版）医药卫生》 2021年第8期125-126,共2页
Objective: to explore the effect of perioperative nursing intervention on joint function of patients with osteoarthritis. Methods: 74 patients with osteoarthritis treated in our hospital from July 2020 to April 2021 w... Objective: to explore the effect of perioperative nursing intervention on joint function of patients with osteoarthritis. Methods: 74 patients with osteoarthritis treated in our hospital from July 2020 to April 2021 were randomly divided into control group and experimental group, with 37 cases in each group. The therapeutic effect of the two groups, routine management of the control group and preoperative management of the experimental group were compared. Results: the joint function recovery rate of the control group was lower than that of the control group, with statistical significance. Conclusion: the preoperative nursing intervention for the patients with osteoarthritis treated by operation can restore the joint function of the patients after operation. 展开更多
关键词 perioperative nursing osteoarthritis joint function
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Dynamic gait parameters reveal long-term compensatory characteristics in knee joint function recovery following anterior cruciate ligament reconstruction:A retrospective cohort study 认领 引用
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作者 Qitai Lin Zehao Li +10 位作者 Meiming Li Yongsheng Ma Wenming Yang Yugang Xing Yang Liu Ruifeng Liang Yixuan Zhang Ruipeng Zhao Wangping Duan Pengcui Li Xiaochun Wei 《Chinese Medical Journal》 SCIE CAS CSCD 2025年第22期3016-3018,共3页
To the Editor:Anterior cruciate ligament(ACL)rupture is a frequent knee injury that modifies knee joint kinematics,including intra-articular motions and forces,leading to recurrent functional instability of the knee.W... To the Editor:Anterior cruciate ligament(ACL)rupture is a frequent knee injury that modifies knee joint kinematics,including intra-articular motions and forces,leading to recurrent functional instability of the knee.With an estimated 200,000 ACL ruptures annually in the United States,ACL ruptures are prevalent,especially in young,physically active individuals.[1]Restoring knee morphology,stability,and function is the aim of conventional therapy,which is ACL reconstruction(ACLR).[2]Previous studies have evaluated gait function at different time points before and after ACLR to quantify impairments in movement patterns and knee joint biomechanics.[3]These investigations have consistently revealed substantial alterations in gait patterns induced by ACLR,with recovery persisting for at least 6 months post-procedure.[4]Majewska et al[4]pointed out that most studies focus on short-term follow-up within 6 months after surgery,while time-dependent changes in long-term dynamic functional recovery remain poorly studied.Accordingly,we aimed to perform gait analysis both pre-ACLR and throughout the 12 months postoperatively,complemented by standard assessments of knee joint function. 展开更多
关键词 knee joint function compensatory characteristics anterior cruciate ligament reconstruction long term recovery cruciate ligament acl rupture dynamic gait parameters conventional therapywhich
The effect of exercise rehabilitation on bone mineral density,muscle strength,and physical function outcomes in ACL ruptures:A randomized controlled clinical trial 认领 引用
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作者 Yue Wu Ruilan Dai +4 位作者 Yunan Zhou Wenqiang Yan Shuang Ren Xi Gong Yingfang Ao 《Sports Medicine and Health Science》 CAS CSCD 2026年第2期185-192,共8页
The purpose is to explore the effects of Exercise rehabilitation(ER)on bone mineral density(BMD)of the knee,muscle strength(MS),and physical function(PF)after ACL rupture.Finally,A total of 58 patients were randomized... The purpose is to explore the effects of Exercise rehabilitation(ER)on bone mineral density(BMD)of the knee,muscle strength(MS),and physical function(PF)after ACL rupture.Finally,A total of 58 patients were randomized into 2 groups(Control Group[CON]:conventional treatment,male=16,female=13,age=[31.63±8.01]years;Exercise rehabilitation group[ER]:6-week ER on CON basis,male=17,female=12,age=[31.26±7.07]years).At baseline and 6 weeks,the knee BMD was measured using DEXA,MS and PF measures were recorded by isokinetic strength test,IKDC,Lysholm,and VAS score.T-tests,analysis of variance(ANOVA),and Mann-Whitney tests were used for comparisons.The BMD outcomes:after a 6-week period,the BMD of the CON([1.47±0.24]g·cm-2)was significantly lower than that of the ER([1.65±0.37]g·cm-2)at lateral condyle of femur(LCF)(p=0.041).MS outcomes:at 6 weeks,the relative peak torque(RPT)of the quadriceps and hamstrings during concentric contractions in ER group were significantly higher than that in CON group(p<0.001,p=0.017).Similarly,during eccentric contractions in ER group,the RPT of the quadriceps and the H/Q ratio revealed significant variations from the CON group(p=0.033,p=0.043).PF outcomes:the IKDC,Lysholm,and VAS scores of the ER group were significantly improved compared to the CON group(p<0.001,p<0.001,p=0.002).The conclusion is that 6 weeks of ER intervention for patients with ACL rupture can effectively delay the decline of BMD in the LCF of the knee joint,and enhance the restoration of MS and PF.This provides guidance for clinical rehabilitation. 展开更多
关键词 Anterior cruciate ligament Rehabilitation Bone mineral density Joint function
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Research on the Causes of Joint Stiffness and Comprehensive Rehabilitation Therapy After Hand and Foot Fracture Surgery 认领 引用
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作者 YU Changle 《外文科技期刊数据库（文摘版）医药卫生》 2026年第6期021-025,共5页
Objective: To investigate the core etiological factors of postoperative joint stiffness in patients with hand and foot fractures, and to evaluate the clinical efficacy and application value of comprehensive rehabilita... Objective: To investigate the core etiological factors of postoperative joint stiffness in patients with hand and foot fractures, and to evaluate the clinical efficacy and application value of comprehensive rehabilitation therapy in this population. Methods: A total of 80 patients with postoperative joint stiffness following hand and foot fractures admitted to our hospital from January 2025 to December 2025 were enrolled as study subjects. They were randomly divided into a conventional treatment group and a rehabilitation group (n=40 each) using a random number table. The conventional group received standard postoperative symptomatic treatment, while the rehabilitation group underwent systematic comprehensive rehabilitation therapy in addition to conventional treatment. The postoperative joint function recovery, clinical treatment efficacy rate, and incidence of complications were compared between the two groups. Results: Post-intervention, the rehabilitation group demonstrated significantly higher joint function scores, greater clinical treatment efficacy, and lower complication rates compared to the conventional group (P<0.05). Conclusion: Postoperative joint stiffness following hand and foot fractures is associated with multiple factors including immobilization, local tissue adhesion, and delayed rehabilitation intervention. Targeted comprehensive rehabilitation therapy can effectively improve joint mobility in these patients. 展开更多
关键词 Hand and foot fractures Postoperative joint stiffness Etiology Comprehensive rehabilitation therapy Joint function
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Joint geostatistical seismic inversion of elastic and petrophysical properties using stochastic co-simulation models based on parametric copulas 认领 引用
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作者 Daniel Vázquez-Ramírez Martín ADíaz-Viera Raúl del Valle-García 《Petroleum Science》 SCIE EI CAS CSCD 2026年第2期608-625,共18页
Seismic properties play a fundamental role in the geological and petrophysical modeling of reservoirs due to their dependence on petrophysical properties.Most existing stochastic seismic inversion methods are based on... Seismic properties play a fundamental role in the geological and petrophysical modeling of reservoirs due to their dependence on petrophysical properties.Most existing stochastic seismic inversion methods are based on Gaussian probability distribution functions and assume linear dependence.Examples include sequential Gaussian co-simulation(SGCS)and direct sequential simulation(DSS).In contrast,spatial stochastic co-simulation methods based on Bernstein copulas(BCCS)have recently been developed.These methods do not require a specific distribution type or linear dependence,thereby overcoming the limitations of traditional approaches.In this context,we propose a novel approach for the joint seismic inversion of elastic and petrophysical properties using parametric copulas within a Bayesian inference framework.A joint probability distribution is constructed using well-scale petrophysical and elastic property data,fitted to parametric copula functions and treated as prior information.The model parameters are then updated a posteriori using petrophysical properties scaled by a moving window averaging method and seismic properties upscaled using the Backus averaging method.The resulting posterior model is used within the inversion process to generate elastic property realizations at the seismic scale.The inverse problem is solved using a simulated annealing algorithm that minimizes a global objective function combining the root-mean-square(RMS)error between synthetic and observed seismic traces,and the semivariogram error between the simulated and target variogram models.For each elastic realization,a reflectivity series is computed and convolved with a seismic wavelet to generate a synthetic seismic trace.The best-fitting elastic realization is then used to simulate the corresponding petrophysical property using the same joint probability distribution.The proposed method was applied to a deepwater reservoir case study to estimate total porosity and acoustic impedance at the seismic scale.Results demonstrate that the use of parametric copulas reduces computational cost and execution time while enabling effective integration of nonlinear dependencies.The synthetic traces exhibit RMS errors below 8%,validating the accuracy and robustness of the copulabased inversion framework. 展开更多
关键词 Geostatistical seismic inversion Bayesian inference Joint probability distribution function Parametric copula Petrophysical simulation Seismic property simulation
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Joint probability density function of the stochastic responses of nonlinear structures 认领 引用 被引量：3
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作者 陈建兵 李杰 《Earthquake Engineering and Engineering Vibration》 SCIE EI 2007年第1期35-47,共13页
The joint probability density fimction （PDF） of different structural responses is a very important topic in the stochastic response analysis of nonlinear structures. In this paper, the probability density evolution ... The joint probability density fimction （PDF） of different structural responses is a very important topic in the stochastic response analysis of nonlinear structures. In this paper, the probability density evolution method, which is successfully developed to capture the instantaneous PDF of an arbitrary single response of interest, is extended to evaluate the joint PDF of any two responses. A two-dimensional partial differential equation in terms of the joint PDF is established. The strategy of selecting representative points via the number theoretical method and sieved by a hyper-ellipsoid is outlined. A two-dimensional difference scheme is developed. The free vibration of an SDOF system is examined to verify the proposed method, and a flame structure exhibiting hysteresis subjected to stochastic ground motion is investigated. It is pointed out that the correlation of different responses results from the fact that randomness of different responses comes from the same set of basic random parameters involved. In other words, the essence of the probabilistic correlation is a physical correlation. 展开更多
关键词 stochastic response nonlinearity joint probability density function probability density evolution method number theoretical method finite difference method
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The Community Promotion of Wax Therapy Combined with Functional Exercise of Hand Joints in Patients with Rheumatoid Arthritis with Swelling and Pain of Hand Joints 认领 引用
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作者 LIChengyan QIXiangjun ZHAOTongzhen 《外文科技期刊数据库（文摘版）医药卫生》 2022年第6期181-185,共5页
Objective: in the treatment of rheumatoid arthritis hand joint swelling and pain, observe the curative effect of using wax therapy with hand joint function exercise, and promote it in the community. Methods: from June... Objective: in the treatment of rheumatoid arthritis hand joint swelling and pain, observe the curative effect of using wax therapy with hand joint function exercise, and promote it in the community. Methods: from June 2020 to December 2021, 60 RA patients screened in the pain department, ward and health management center of our hospital were selected and divided into 30 control group with routine treatment and care, and 30 observation group with routine treatment and care and wax therapy and hand joint function exercise. Results: the pain index, self-care ability, morning stiffness time and joint mobility before and after the patients in the observation group were better than the control group. Conclusion: in the treatment of hand joint swelling and pain in rheumatoid arthritis, routine treatment and care for the observation group and wax therapy and hand joint function exercise have significant effect in treatment and is worth promoting in the community. 展开更多
关键词 wax therapy with hand joint function exercise rheumatoid arthritis hand joint swelling and pain community promotion
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丁香脂素对膝骨关节炎的治疗作用及机制研究 认领 引用 被引量：1
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作者 王若秦 陈飞飞 +2 位作者 郑永智 张果 贾洋洋 《云南民族大学学报（自然科学版）》 CAS 2026年第1期77-85,116,共9页
探讨丁香脂素(Syr)对膝骨关节炎(KOA)大鼠的软骨保护作用及TLR4/NF-κB通路调控机制.采用改良Hulth法构建SD大鼠KOA模型,30只大鼠随机分为假手术组、模型组、阳性药组(吲哚美辛,10 mg/kg)及Syr低、高剂量组(25、50 mg/kg),每组6只.结果... 探讨丁香脂素(Syr)对膝骨关节炎(KOA)大鼠的软骨保护作用及TLR4/NF-κB通路调控机制.采用改良Hulth法构建SD大鼠KOA模型,30只大鼠随机分为假手术组、模型组、阳性药组(吲哚美辛,10 mg/kg)及Syr低、高剂量组(25、50 mg/kg),每组6只.结果显示,与模型组相比,Syr干预组大鼠运动功能显著改善(P<0.01),血清IL-1β、MMP13水平下降(P<0.01),软骨病理损伤减轻.蛋白免疫印迹及实时荧光定量聚合酶链式反应证实Syr可剂量依赖性下调软骨组织TLR4、P-NF-κB蛋白及mRNA表达(P<0.01),同时显著提升Ⅱ型胶原蛋白表达(P<0.01).机制研究表明,Syr通过抑制TLR4/NF-κB信号通路活化,有效缓解关节炎症并延缓软骨基质降解.上述结果为丁香脂素防治KOA和中医药现代化发展提供了理论依据. 展开更多
关键词 丁香脂素 膝骨性关节炎 关节功能 软骨保护 TLR4/NF-κB信号通路
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老年股骨转子间骨折患者PFNA术后髋关节功能不良风险等级预测模型的构建和评价 认领 引用 被引量：1
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作者 武志刚 张海东 刘海洋 《临床误诊误治》 CAS 2026年第1期44-52,共9页
目的构建老年股骨转子间骨折患者股骨近端防旋髓内钉(PFNA)术后髋关节功能不良的风险等级预测模型,并评价其效能。方法选取2021年1月至2023年6月收治的208例老年股骨转子间骨折患者为研究对象,通过一般资料调查表、医院电子病历系统、Ha... 目的构建老年股骨转子间骨折患者股骨近端防旋髓内钉(PFNA)术后髋关节功能不良的风险等级预测模型,并评价其效能。方法选取2021年1月至2023年6月收治的208例老年股骨转子间骨折患者为研究对象,通过一般资料调查表、医院电子病历系统、Harris髋关节功能评分系统、恐动症Tampa量表进行问卷调查。采用单因素、多因素Logistic回归分析老年股骨转子间骨折患者PFNA术后髋关节功能不良的影响因素,将Logistic回归分析中有意义变量纳入列线图模型,采用受试者工作特征(ROC)曲线验证其效能,根据个体携带的危险因素,运用列线图模型计算患者PFNA术后髋关节功能不良的风险总得分及其风险概率,并根据风险总得分进行危险等级划分。结果最终完成206例老年股骨转子间骨折患者的随访及资料收集,Harris髋关节功能评分(86.12±7.32)分,髋关节功能预后良好率为75.24%(155/206),预后不良率为24.76%(51/206)。单因素、多因素Logistic回归分析显示,超重/肥胖、不稳定性骨折、手术时机≥7 d、Clavien-Dindo分级、恐动症、营养不良、骨质疏松症、血清Ⅰ型胶原氨基端前肽、血清骨织素均为老年股骨转子间骨折患者PFNA术后髋关节功能不良的独立危险因素,而功能锻炼依从性、血清25羟维生素D3是其保护因素(P160~200分)、高风险(>200分)3个等级,对应概率分别为≤10%、>10%~50%、>50%。结论超重/肥胖、营养不良、骨质疏松症等是老年股骨转子间骨折患者PFNA术后髋关节功能不良的影响因素,以此为基础构建的列线图模型具有良好临床预测效用,可指导临床建立风险预警模式。 展开更多
关键词 股骨转子间骨折 老年 股骨近端防旋髓内钉 髋关节功能 危险因素 预测模型 列线图
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Expert consensus on treatment of condylar hyperplasia and secondary dento-maxillofacial deformities 认领 引用
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作者 Ruiye Bi Bassam M.Abotaleb +39 位作者 Xiaofeng Bai Kun Cao Gang Chen Jie Cheng Weihua Guo Min Hu Li Huang Xuanping Huang Hongbing Jiang Lingyong Jiang Xiaolei Jin Feiwu Kang Tangxin Li Wenyang Li Shuguang Liu Yanpu Liu Yanshan Liu Li Lu Yisen Shao Bin Shi Guodong Song Yuxiong Su Jian Sun Zhenglong Tang Lei Tian Maimaitituxun Tuerdi Qilong Wan Xiaoxia Wang Xuejiu Wang Yong Wang Guomin Wu Zhijian Xie Guangqi Yan Xuewen Yang Meng You Fenghe Zhang Shilei Zhang Guangsen Zheng Songsong Zhu En Luo 《International Journal of Oral Science》 SCIE CAS CSCD 2026年第3期347-356,共10页
Condylar hyperplasia(CH),characterized by progressive facial deviation,occlusion disorders,and temporomandibular joint dysfunction,often requires combined temporomandibular joint(TMJ)-orthognathic interventions to rec... Condylar hyperplasia(CH),characterized by progressive facial deviation,occlusion disorders,and temporomandibular joint dysfunction,often requires combined temporomandibular joint(TMJ)-orthognathic interventions to reconstruct joint and occlusal functions as well as rebuilding harmonious facial expressions.Managing the dentomaxillofacial deformities secondary to CH involves hyperplastic condylar resection,orthognathic surgery,facial contour surgery and orthodontic treatment.Based on the activity of condylar hypertrophy,the severity of dentomaxillofacial deformity and malocclusion,an individualized treatment plan should be formulated to reconstruct joint functions,correct deformities and recover occlusal relationships.This expert consensus,informed by the latest clinical research and practical experience,addresses clinical considerations for surgical treatment strategies for patients with different CH types,delineating indications,objectives,procedures,and principles with the aim of providing clear and practical guidance for clinical practitioners. 展开更多
关键词 condylar hyperplasia ch characterized reconstruct joint occlusal functions condylar hy orthodontic treatmentbased hyperplastic condylar resectionorthognathic surgeryfacial contour surgery dentomaxillofacial deformities temporomandibular joint dysfunctionoften progressive facial deviationocclusion disordersand
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手法复位联合小夹板固定治疗桡骨远端骨折的临床疗效及影像学指标分析——一项倾向性评分匹配的回顾性多中心研究 认领 引用
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作者 吴毛 戴国达 +10 位作者 邵阳 李绍烁 华臻 崔恒燕 朱庭辰 励迪鹏 刘锦涛 周明 王培民 张利勇 王建伟 《中医杂志》 CSCD 北大核心 2026年第10期1086-1092,共7页
目的观察手法复位联合小夹板固定治疗桡骨远端骨折的临床疗效以及对影像学指标的影响。方法回顾性收集江苏省中医优势病种诊疗数据大平台中5家医院的1051例桡骨远端骨折患者的病例资料,根据倾向性评分匹配法按1∶4进行匹配,共纳入580例... 目的观察手法复位联合小夹板固定治疗桡骨远端骨折的临床疗效以及对影像学指标的影响。方法回顾性收集江苏省中医优势病种诊疗数据大平台中5家医院的1051例桡骨远端骨折患者的病例资料,根据倾向性评分匹配法按1∶4进行匹配,共纳入580例患者资料,其中中医治疗组(手法复位联合小夹板固定)448例,手术治疗组(手术切开复位内固定)132例。每组根据骨折AO分型再分为A、B、C型。比较两组治疗前及治疗后1天、1周、4~6周的影像学指标(掌倾角、尺偏角、桡骨高度),治疗前及治疗后1周、4~6周的疼痛视觉模拟量表(VAS)评分,治疗后12周根据Dienst腕关节功能评分、Gartland与Werley腕关节评分(G-W评分)的腕关节功能等级;再比较不同骨折分型中两组患者上述不同时间的影像学指标,以及治疗后12周腕关节功能等级。结果两组治疗前后各时间点影像学指标、VAS评分比较差异均无统计学意义,治疗后12周根据Dienst腕关节功能评分和G-W评分的腕关节功能等级比较差异亦无统计学意义(P>0.05)。与本组治疗前比较,两组治疗后1周及治疗后4~6周掌倾角、尺偏角及桡骨高度增加,VAS评分降低(P<0.05)。与本组治疗后1周比较,两组治疗后4~6周掌倾角减小,尺偏角及桡骨高度增加,VAS评分降低(P<0.05)。A、B型骨折中,手术治疗组治疗后4~6周尺偏角高于中医治疗组;C型骨折中,手术治疗组治疗后4~6周桡骨高度高于中医治疗组(P<0.05)。C型骨折中,两组治疗后12周根据G-W评分的腕关节功能等级比较差异具有统计学意义(P<0.05)。结论手法复位联合小夹板固定治疗桡骨远端骨折能维持骨折形态,减轻疼痛,疗效与手术治疗相当,且尤适用于A、B型骨折,可作为桡骨远端骨折的有效治疗方法。 展开更多
关键词 桡骨远端骨折 手法复位 小夹板固定 手术复位 腕关节功能
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股骨远端骨折松解术中活动度与术后膝关节功能的关系:多因素预测模型验证 认领 引用
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作者 董瑞波 唐东鸣 +2 位作者 费奉龙 陈封明 汤永南 《中国组织工程研究》 CAS 北大核心 2026年第27期7135-7141,共7页
背景:股骨远端骨折术后膝关节僵硬是患者功能恢复的核心问题,其病理机制涉及伸膝装置粘连、关节囊挛缩、关节面形态异常等因素。目的:探讨关节镜联合小切口粘连松解治疗股骨远端骨折术后伸直性膝关节僵硬的疗效,并分析影响膝关节功能恢... 背景:股骨远端骨折术后膝关节僵硬是患者功能恢复的核心问题,其病理机制涉及伸膝装置粘连、关节囊挛缩、关节面形态异常等因素。目的:探讨关节镜联合小切口粘连松解治疗股骨远端骨折术后伸直性膝关节僵硬的疗效,并分析影响膝关节功能恢复的危险因素。方法:选择2019年3月至2024年10月广州市中西医结合医院收治的股骨远端骨折术后非感染性伸直性膝关节僵硬患者152例,根据松解术后6个月美国特种外科医院膝关节评分分为恢复良好组(≥70分,n=122)和恢复较差组(<70分,n=30)。收集患者年龄、复位质量、连续被动运动功能锻炼等临床资料,采用单因素及多因素Logistic回归分析法筛选危险因素,建立预测模型并通过受试者工作特征曲线、校准曲线和决策曲线评估模型效能。结果与结论:①单因素分析显示年龄≥60岁、非解剖复位、无连续被动运动锻炼、术后并发症、术中屈伸活动度<120°、术前胫骨内侧关节线改变程度增大及术前美国特种外科医院膝关节评分降低与术后功能恢复较差显著相关(均P<0.05);②多因素分析确认年龄≥60岁、无连续被动运动锻炼、术后并发症、术中活动度<120°、术前美国特种外科医院膝关节评分低及胫骨内侧关节线改变大为独立危险因素(均P<0.05);③阈值效应分析揭示术中活动度与恢复风险呈非线性关系(P<0.001),120°为拐点,活动度<120°时,每增加1°恢复风险降低3.3%(OR=0.967);≥120°时风险不再显著降低(P=0.073);④预测模型的区分度(曲线下面积=0.821,95%CI:0.760-0.953)、校准度(Brier值=0.097)及临床净收益(决策曲线阈值0.1-0.9)均表现良好。提示:股骨远端骨折术后膝关节僵硬患者功能恢复与术中活动度阈值(120°)、年龄、康复管理及术前关节状态密切相关,基于6项独立危险因素构建的预测模型具有良好效能,可为临床干预提供依据。 展开更多
关键词 股骨骨折 膝关节僵硬 松解术 膝关节功能 预后 预测模型
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