Figure 6(a)in the paper[Chin.Phys.B 33074203(2024)]was incorrect due to editorial oversight.The correct figure is provided.This modification does not affect the result presented in the paper.
The naturally fermented Inner Mongolian cheese’s flavor and nutritional value make it a popular choice among customers.In this work,to create multi-functional peptides that have taste and biological activity,peptidom...The naturally fermented Inner Mongolian cheese’s flavor and nutritional value make it a popular choice among customers.In this work,to create multi-functional peptides that have taste and biological activity,peptidomics and bioinformatics were used to screen flavor peptides from Inner Mongolian cheese and further assess their antioxidant and angiotensin I-converting enzyme(ACE)inhibitory properties.According to sensory data,YH8 and IL7 had detectable bitter tastes with low thresholds of 0.03 and 0.06 mmol/L,respectively.With an umami threshold range of 0.24‒0.81 mmol/L,VQ6,FK13,HP13 and QT14 exhibited a range of flavors dominated by umami,including sweet,bitter,salty,sour and kokumi.Antioxidant activity wise,YH8,VQ6,HP13 and QT14 were well represented.The above-mentioned peptides all had some ACE inhibitory effect.The bitter peptide IL7(IC50=0.08 mmol/L)had the highest level of ACE inhibitory activity,followed by YH8(IC50=0.33 mmol/L).These multi-functional peptides,which have been assessed for bioactive and taste features in Inner Mongolian cheese,may have positive impacts on health and harmonize the cheese’s overall flavor.These results suggest that some flavor peptides produced in fermented foods might be with bioactivities while providing a basis for the exploration and application of multi-functional peptides.展开更多
Eavesdropping on heterospecific alarm signals provides critical predator information,yet whether recognition is driven by innate phylogenetic biases or learning and ecology remains unclear.We hypothesize that decoding...Eavesdropping on heterospecific alarm signals provides critical predator information,yet whether recognition is driven by innate phylogenetic biases or learning and ecology remains unclear.We hypothesize that decoding strategies arise from interactions between evolutionarily inherited perceptual biases and current ecological adaptations.To test this,we chose Asian Tits(Parus cinereus minor)as an“information hub species”,along with the Green-backed Tits(P.monticolus)and the Coal Tits(Periparus ater),forming a phylogenetic gradient.Playbacks used three call types:territorial song,ground alarm calls(hereafter“alarms”),and aerial alarms.Results demonstrated that Asian Tits exhibited a strong conspecific bias exclusively for ground alarms:fleeing probability in response to conspecific ground alarms(79.3%)was significantly higher than to heterospecific ground alarms,with no difference between the two heterospecific sources.Coal Tits were 2.89 times more likely to flee than Green-backed Tits in response to Asian Tit calls.These results support a binary conspecific-heterospecific distinction for ground threats,not a phylogenetic gradient.Decoding is call-type-specific:ground alarms elicit accuracy-driven responses,whereas aerial alarms permit more permissive decoding.Thus,heterospecific alarm decoding is shaped by signal function,a clear conspecific dichotomy and ecological niche,not by fine-scale phylogenetic distance.展开更多
Power system faults can trigger a massive influx of complex alarm signals to the operation and maintenance center,posing significant challenges for dispatchers in accurately identifying the underlying faults.To addres...Power system faults can trigger a massive influx of complex alarm signals to the operation and maintenance center,posing significant challenges for dispatchers in accurately identifying the underlying faults.To address the issues of sample imbalance and low accuracy in traditional power grid monitoring alarm event identification methods,a power grid monitoring alarm event identification method based on BERT large language model is proposed.Firstly,information entropy is employed to filter effective monitoring alarm signals,and the k-means clustering algorithm is used to group all alarm signals into different event types,forming the initial power grid monitoring alarm event samples.Then,to mitigate the issue of sample imbalance in power grid monitoring alarm events,a pre-trained SimBERT model is proposed to augment minority class samples,thereby reducing the imbalance ratio.Finally,the augmented samples of power grid monitoring alarm events are used to fine-tune the bidirectional encoder representation from transformer(BERT)model.A mix-training optimization strategy is adopted during fine-tuning to ultimately obtain the power grid monitoring alarm event identification model.Case study results demonstrate that the proposed model in this paper achieves superior identification precision of power grid monitoring alarm events compared to traditional deep learning methods.展开更多
With great differences in wind speed changes along the lines of high-speed railways,it cannot meet the operation and maintenance requirements on improving the riding comfort and the efficiency of train operation by us...With great differences in wind speed changes along the lines of high-speed railways,it cannot meet the operation and maintenance requirements on improving the riding comfort and the efficiency of train operation by using the unified alarm threshold at all wind monitoring points along the entire railway line under the current rules of gale alarm.Based on the historical wind monitoring data collected from multiple high-speed railway lines and combined with the analysis of the alarm mechanism,this paper proposes the methods for improving the gale alarm triggering rules and the time limit threshold for gale alarm release.Verifications are carried out by using the wind monitoring data,which show that the methods proposed achieve the identification of potential short-time strong winds and the adaptive setting of alarm thresholds at wind monitoring points.The methods can further improve the train operation efficiency,alleviate the potential impact of instantaneous strong winds on the stability of train operation,and enjoy a good prospect of application.展开更多
Multi-functional Al-matrix composites with high volume fraction (55%-57%) of SiC particles are produced with the new pressureless infiltration fabrication technology. X-ray detection and microscopic observation disp...Multi-functional Al-matrix composites with high volume fraction (55%-57%) of SiC particles are produced with the new pressureless infiltration fabrication technology. X-ray detection and microscopic observation display the composites which are macroscopically homogeneous without porosity. The investigation further reveals that the SiC/Al composites possess low density (2.94 g/cm^3), high elastic modulus (220 GPa), prominent thermal management function as a result of low coefficient of thermal expansion (8 × 10^4 K^-1) and high thermal conductivity (235 W/(m.K)) as well as unique preventability of resonance vibration. By adopting a series of developed techniques, the multi-functional SiC/Al composites have managed to be made into near-net-shape parts. Many kinds of precision components of space-based optomechanical structures and airborne optoelectronic platform have been turned out. Of them, several typical products are being under test in practices.展开更多
The robust magnesium surfaces with multi-functions are highly desirable,and the simple and scalable methods to construct such surfaces are urgently indispensable.Herein,we conducted a one-step spraying method to facil...The robust magnesium surfaces with multi-functions are highly desirable,and the simple and scalable methods to construct such surfaces are urgently indispensable.Herein,we conducted a one-step spraying method to facilely fabricate the robust coating with multi-functions on magnesium alloys.The as-sprayed magnesium alloys surface is superhydrophobic with a static water contact angle(WCA)of 157.0°and a roll-off angle of 6.0°.Such surface has excellent mechanical,chemical and thermal stabilities,even undergoing various physical and chemical damages,including sand impact(10 gmin-1,≥20 min),water impact(2 impacts s-1,≥180 min),abrasion(1.00 kPa,≥25 cycles),peeling(≥2.15 kPa),high temperature(200°C,≥24 h),strong acidic/salty/basic media(p H=113)and organic-solvent immersion(ethanol and n-hexane,≥24 h),demonstrating brilliant robustness.Notably,the surface displays multi-functions of corrosion protection,anti-fouling and heat insulation,which will undoubtedly promote the much wider applications of magnesium alloys.展开更多
To fulfill the demands for higher quality,efficiency and flexibility in aviation industry,a multi-functional end effector is designed to automate the drilling and riveting processes in assembling carbon fiber reinforc...To fulfill the demands for higher quality,efficiency and flexibility in aviation industry,a multi-functional end effector is designed to automate the drilling and riveting processes in assembling carbon fiber reinforced polymer(CFRP)and aluminum components for a robotic aircraft assembly system.To meet the specific functional requirements for blind rivet installation on CFRP and aluminum materials,additional modules are incorporated on the end effector aside of the basic processing modules for drilling.And all of these processing modules allow for a onestep-drilling-countersinking process,hole inspection,automatic rivet feed,rivet geometry check,sealant application,rivet insertion and installation.Besides,to guarantee the better quality of the hole drilled and joints riveted,several online detection and adjustment measures are applied to this end effector,including the reference detection and perpendicular calibration,which could effectively ensure the positioning precision and perpendicular accuracy as demanded.Finally,the test result shows that this end effector is capable of producing each hole to a positioning precision within ±0.5 mm,aperpendicular accuracy within 0.3°,a diameter tolerance of H8,and a countersink depth tolerance of±0.01 mm.Moreover,it could drill and rivet up to three joints per minute,with acceptable shearing and tensile strength.展开更多
Folate receptor(FR)overexpression occurs in a variety of cancers,including pancreatic cancer.In addition,enhanced macropinocytosis exists in K-Ras mutant pancreatic cancer.Furthermore,the occurrence of intensive desmo...Folate receptor(FR)overexpression occurs in a variety of cancers,including pancreatic cancer.In addition,enhanced macropinocytosis exists in K-Ras mutant pancreatic cancer.Furthermore,the occurrence of intensive desmoplasia causes a hypoxic microenvironment in pancreatic cancer.In this study,a novel FR-directed,macropinocytosis-enhanced,and highly cytotoxic bioconjugate folate(F)-human serum albumin(HSA)-apoprotein of lidamycin(LDP)-active enediyne(AE)derived from lidamycin was designed and prepared.F-HSA-LDP-AE consisted of four moieties:F,HSA,LDP,and AE.F-HSA-LDP presented high binding efficiency with the FR and pancreatic cancer cells.Its uptake in wild-type cells was more extensive than in K-Ras mutant-type cells.By in vivo optical imaging,F-HSA-LDP displayed prominent tumor-specific biodistribution in pancreatic cancer xenograft-bearing mice,showing clear and lasting tumor localization for 360 h.In the MTT assay,F-HSA-LDP-AE demonstrated potent cytotoxicity in three types of pancreatic cancer cell lines.It also induced apoptosis and caused G2/M cell cycle arrest.F-HSALDP-AE markedly suppressed the tumor growth of AsPc-1 pancreatic cancer xenografts in athymic mice.At well-tolerated doses of 0.5 and 1 mg/kg,(i.v.,twice),the inhibition rates were 91.2%and 94.8%,respectively(P<0.01).The results of this study indicate that the F-HSA-LDP multi-functional bioconjugate might be effective for treating K-Ras mutant pancreatic cancer.展开更多
Photonic spin Hall effect(PSHE), as a novel physical effect in light–matter interaction, provides an effective metrological method for characterizing the tiny variation in refractive index(RI). In this work, we propo...Photonic spin Hall effect(PSHE), as a novel physical effect in light–matter interaction, provides an effective metrological method for characterizing the tiny variation in refractive index(RI). In this work, we propose a multi-functional PSHE sensor based on VO2, a material that can reveal the phase transition behavior. By applying thermal control, the mutual transformation into different phase states of VO2 can be realized, which contributes to the flexible switching between multiple RI sensing tasks. When VO2 is insulating, the ultrasensitive detection of glucose concentrations in human blood is achieved. When VO2 is in a mixed phase, the structure can be designed to distinguish between the normal cells and cancer cells through no-label and real-time monitoring. When VO2 is metallic, the proposed PSHE sensor can act as an RI indicator for gas analytes. Compared with other multi-functional sensing devices with the complex structures, our design consists of only one analyte and two VO2 layers, which is very simple and elegant. Therefore, the proposed VO2-based PSHE sensor has outstanding advantages such as small size, high sensitivity, no-label, and real-time detection, providing a new approach for investigating tunable multi-functional sensors.展开更多
To cope with the problem of emitter identification caused by the radar words' uncertainty of measured multi-function radar emitters, this paper proposes a new identification method based on stochastic syntax-directed...To cope with the problem of emitter identification caused by the radar words' uncertainty of measured multi-function radar emitters, this paper proposes a new identification method based on stochastic syntax-directed translation schema(SSDTS). This method, which is deduced from the syntactic modeling of multi-function radars, considers the probabilities of radar phrases appearance in different radar modes as well as the probabilities of radar word errors occurrence in different radar phrases. It concludes that the proposed method can not only correct the defective radar words by using the stochastic translation schema, but also identify the real radar phrases and working modes of measured emitters concurrently. Furthermore, a number of simulations are presented to demonstrate the identification capability and adaptability of the SSDTS algorithm.The results show that even under the condition of the defective radar words distorted by noise,the proposed algorithm can infer the phrases, work modes and types of measured emitters correctly.展开更多
Avian alarm calls mediate defenses against brood parasites and predators. These calls facilitate communication among adults and alert nestlings to potential danger. While heterospecific call recognition has been exten...Avian alarm calls mediate defenses against brood parasites and predators. These calls facilitate communication among adults and alert nestlings to potential danger. While heterospecific call recognition has been extensively studied in adult birds, nestlings—lacking direct predation experience and heterospecific alarm exposure—represent an ideal system to investigate the response to interspecific warning cues. This study explored the recognition capabilities of 5–6-day-old nestlings in Oriental Reed Warbler (Acrocephalus orientalis), a common host of the Common Cuckoo (Cuculus canorus). We exposed the nestlings to playbacks of alarm calls directed at parasites and raptors from conspecific, Vinous-throated Parrotbill (Sinosuthora webbiana, sympatric species), Isabelline Shrike (Lanius isabellinus, allopatric species) and Common Tailorbird (Orthotomus sutorius, allopatric species) adults. Results indicated that there was no significant difference in the responses of nestlings to the alarm calls of conspecific and allopatric adults directed at cuckoos and sparrowhawks. In addition, interestingly, nestlings significantly reduced their begging in response to conspecific and unfamiliar allopatric Isabelline Shrike and Common Tailorbird alarm calls but exhibited a weak response to the sympatric Vinous-throated Parrotbill. Whether older warbler nestlings with more social experience exhibit stronger responses to the alarm calls of Vinous-throated Parrotbill adults requires further investigation.展开更多
We propose a novel and efficient multi-functional optical fiber sensor system based on a dense wavelength division multiplexer(DWDM).This system consists of an optical fiber temperature sensor, an optical fiber strain...We propose a novel and efficient multi-functional optical fiber sensor system based on a dense wavelength division multiplexer(DWDM).This system consists of an optical fiber temperature sensor, an optical fiber strain sensor, and a 48-channel DWDM.This system can monitor temperature and strain changes at the same time.The ranges of these two sensors are from-20℃ to 100℃ and from-1000 με to 2000 με, respectively.The sensitivities of the temperature sensor and strain sensor are 0.03572 nm/℃ and 0.03808 nm/N, respectively.With the aid of a broadband source and spectrometer,different kinds and ranges of parameters in the environment can be monitored by using suitable sensors.展开更多
Emitting alarm calls may be costly,but few studies have asked whether calling increases a caller’s risk of predation and survival.Since observing animals calling and being killed is relatively rare,we capitalized on ...Emitting alarm calls may be costly,but few studies have asked whether calling increases a caller’s risk of predation and survival.Since observing animals calling and being killed is relatively rare,we capitalized on over 24,000 h of observations of marmot colonies and asked whether variation in the rate that yellow-bellied marmots(Marmota faviventer)alarm called was associated with the probability of summer mortality,a proxy for predation.Using a generalized mixed model that controlled for factors that infuenced the likelihood of survival,we found that marmots who called at higher rates were substantially more likely to die over the summer.Because virtually all summer mortality is due to predation,these results suggest that calling is indeed costly for marmots.Additionally,the results from a Cox survival analysis showed that marmots that called more lived signifcantly shorter lives.Prior studies have shown that marmots reduce the risk by emitting calls only when close to their burrows,but this newly quantifed survival cost suggests a constraint on eliminating risks.Quantifying the cost of alarm calling using a similar approach in other systems will help us better understand its true costs,which is an essential value for theoretical models of calling and social behavior.展开更多
A new appraisal method(QDA, quasi-distribution appraisal) which could be used to evaluate the finite element analysis of multi-functional structure made of honeycomb sandwich materials is developed based on sub-sect...A new appraisal method(QDA, quasi-distribution appraisal) which could be used to evaluate the finite element analysis of multi-functional structure made of honeycomb sandwich materials is developed based on sub-section Bezier curve. It is established by simulating the distribution histogram data obtained from the numerical finite element analysis values of a satellite component with sub-section Bezier curve. Being dealt with area normalization method, the simulation curve could be regarded as a kind of probability density function(PDF), its mathematical expectation and the variance could be used to evaluate the result of finite element analysis. Numerical experiments have indicated that the QDA method demonstrates the intrinsic characteristics of the finite element analysis of multi-functional structure made of honeycomb sandwich materials, as an appraisal method, it is effective and feasible.展开更多
Metal-organic frameworks(MOFs) are a unique class of porous crystalline materials that have shown promise for a wide range of applications. MOFs have been explored as a new type of heterogeneous catalytic materials,...Metal-organic frameworks(MOFs) are a unique class of porous crystalline materials that have shown promise for a wide range of applications. MOFs have been explored as a new type of heterogeneous catalytic materials, because of their high surface area, uniform and tunable pores, facile functionalization and incorporation of catalytic active sites. The use of multi-functional sites MOF materials as catalysts for synergistic catalysis and tandem reactions has attracted increasing attention. In this review, we aim to introduce the construction of bi-or multi-functional MOF catalysts with cooperative or cascade functions via post-synthetic modification(PSM).展开更多
There are multiple types of risks involved in the service of long-span railway bridges.Classical methods are difficult to provide targeted alarm information according to different situations of load anomalies and stru...There are multiple types of risks involved in the service of long-span railway bridges.Classical methods are difficult to provide targeted alarm information according to different situations of load anomalies and structural anomalies.To accurately alarm different risks of long-span railway bridges by structural health monitoring systems,this paper proposes a cross-cooperative alarm method using principal and secondary indicators during high-wind periods.It provides the prior criterion for monitoring systems under special conditions,defining the principal and secondary indicators,alarm levels,and thresholds based on the relationship between dynamic equilibrium equations and multiple linear regression analysis.Analysis of one-year monitoring data from a longspan railway cable-stayed bridge shows that the 10-min average cross-bridge wind speed(excitation indicator)can be selected as the principal indicator,while lateral displacement(response indicator)can serve as the secondary indicator.The threshold levels of the secondary indicator prioritize the safety of bridge operation(mainly aiming at the safety of trains traversing bridges),with values significantly lower than structural safety thresholds.This approach enhances alarm timeliness and effectively distinguishes between load anomalies,structural anomalies,and equipment failures.Consequently,it improves alarm accuracy and provides timely decision support for bridge maintenance,train traversing,and emergency treatment.展开更多
Fiber-shaped supercapacitors(FSSCs)show great potential in portable and wearable electronics due to their unique advantages of high safety,environmental friendliness,high performances,outstanding flexibility and integ...Fiber-shaped supercapacitors(FSSCs)show great potential in portable and wearable electronics due to their unique advantages of high safety,environmental friendliness,high performances,outstanding flexibility and integrability.They can directly act as the power sources or be easily integrated with other flexible devices to constitute self-powered and sustainable energy suppliers,providing excellent adaptability to irregular surfaces.This review mainly summarizes the recently reported works of FSSCs including preparation methods of various fiber electrodes,construction strategies of FSSCs and multi-functional device integrations,exploration of reaction mechanisms and strategies to improve the electrochemical performance and provision of suggestions on further designing and optimization of FSSCs.Meanwhile,it shares our perspectives on challenges and opportunities in this field,shedding light on the development of high-performance fiber-shaped supercapacitors with multifunctions.展开更多
Calcium is a critical second messenger molecule in all cells and is vital in neurons for synaptic transmission.Given this importance,calcium ions are tightly controlled by a host of molecular players including ion cha...Calcium is a critical second messenger molecule in all cells and is vital in neurons for synaptic transmission.Given this importance,calcium ions are tightly controlled by a host of molecular players including ion channels,sensors,and buffering proteins.Calcium can act directly by binding to signaling molecules or calcium’s effects can be indirect,for example by altering nuclear histones.展开更多
Alarm calls in bird vocalizations serve as acoustic signals announcing danger.Owing to the convergent evolution of alarm calls,some bird species can beneft from eavesdropping on certain parameters of alarm calls of ot...Alarm calls in bird vocalizations serve as acoustic signals announcing danger.Owing to the convergent evolution of alarm calls,some bird species can beneft from eavesdropping on certain parameters of alarm calls of other species.Vocal mimicry,displayed by many bird species,aids defense against predators and may help brood parasites during parasitism.In the coevolutionary dynamics between brood parasites,such as the common cuckoo(Cuculus canorus),and their hosts,female cuckoo vocalizations can induce hosts to leave the nest,increasing the probability of successful parasitism and reducing the risk of host attacks.Such cuckoo calls were thought to mimic those of the sparrowhawk.However,owing to their similarity to alarm calls,we propose a new hypothesis:Female cuckoos cheat their hosts by mimicking the parameters of the host alarm call.In this study,we tested this new hypothesis and the sparrowhawk mimicry hypothesis simultaneously by manipulating the syllable rate in male and female common cuckoo vocalizations and playing them in front of the host Oriental reed warbler(Acrocephalus orientalis)for examination.The results indicate that similar to a normal female cuckoo call,a female call with a reduced syllable rate prompted the hosts to leave their nests more frequently and rapidly than male cuckoo calls.Additionally,the male cuckoo calls with increased syllable rate did not prompt the host to leave their nests more frequently or quickly compared with the male cuckoo calls with a normal syllable rate.Our results further confrm that female common cuckoos mimic the vocalizations of Eurasian sparrowhawks(Accipiter nisus),reveal the function mechanisms underlying such mimicry,and support the theory of imperfect mimicry.展开更多
摘要Figure 6(a)in the paper[Chin.Phys.B 33074203(2024)]was incorrect due to editorial oversight.The correct figure is provided.This modification does not affect the result presented in the paper.
基金supported by the central government and guides local funds for science and technology development(2022ZY0109).
摘要The naturally fermented Inner Mongolian cheese’s flavor and nutritional value make it a popular choice among customers.In this work,to create multi-functional peptides that have taste and biological activity,peptidomics and bioinformatics were used to screen flavor peptides from Inner Mongolian cheese and further assess their antioxidant and angiotensin I-converting enzyme(ACE)inhibitory properties.According to sensory data,YH8 and IL7 had detectable bitter tastes with low thresholds of 0.03 and 0.06 mmol/L,respectively.With an umami threshold range of 0.24‒0.81 mmol/L,VQ6,FK13,HP13 and QT14 exhibited a range of flavors dominated by umami,including sweet,bitter,salty,sour and kokumi.Antioxidant activity wise,YH8,VQ6,HP13 and QT14 were well represented.The above-mentioned peptides all had some ACE inhibitory effect.The bitter peptide IL7(IC50=0.08 mmol/L)had the highest level of ACE inhibitory activity,followed by YH8(IC50=0.33 mmol/L).These multi-functional peptides,which have been assessed for bioactive and taste features in Inner Mongolian cheese,may have positive impacts on health and harmonize the cheese’s overall flavor.These results suggest that some flavor peptides produced in fermented foods might be with bioactivities while providing a basis for the exploration and application of multi-functional peptides.
基金supported by the National Natural Science Foundation of China(No.32470513 to W.L.)supported by the 2023 Ningxia Hui Autonomous Region Youth Science and Technology Support Talent Training Project。
摘要Eavesdropping on heterospecific alarm signals provides critical predator information,yet whether recognition is driven by innate phylogenetic biases or learning and ecology remains unclear.We hypothesize that decoding strategies arise from interactions between evolutionarily inherited perceptual biases and current ecological adaptations.To test this,we chose Asian Tits(Parus cinereus minor)as an“information hub species”,along with the Green-backed Tits(P.monticolus)and the Coal Tits(Periparus ater),forming a phylogenetic gradient.Playbacks used three call types:territorial song,ground alarm calls(hereafter“alarms”),and aerial alarms.Results demonstrated that Asian Tits exhibited a strong conspecific bias exclusively for ground alarms:fleeing probability in response to conspecific ground alarms(79.3%)was significantly higher than to heterospecific ground alarms,with no difference between the two heterospecific sources.Coal Tits were 2.89 times more likely to flee than Green-backed Tits in response to Asian Tit calls.These results support a binary conspecific-heterospecific distinction for ground threats,not a phylogenetic gradient.Decoding is call-type-specific:ground alarms elicit accuracy-driven responses,whereas aerial alarms permit more permissive decoding.Thus,heterospecific alarm decoding is shaped by signal function,a clear conspecific dichotomy and ecological niche,not by fine-scale phylogenetic distance.
基金funded by Science and Technology Project of State Grid Jiangsu Electric Power Co.Ltd.(No.J2024172).
摘要Power system faults can trigger a massive influx of complex alarm signals to the operation and maintenance center,posing significant challenges for dispatchers in accurately identifying the underlying faults.To address the issues of sample imbalance and low accuracy in traditional power grid monitoring alarm event identification methods,a power grid monitoring alarm event identification method based on BERT large language model is proposed.Firstly,information entropy is employed to filter effective monitoring alarm signals,and the k-means clustering algorithm is used to group all alarm signals into different event types,forming the initial power grid monitoring alarm event samples.Then,to mitigate the issue of sample imbalance in power grid monitoring alarm events,a pre-trained SimBERT model is proposed to augment minority class samples,thereby reducing the imbalance ratio.Finally,the augmented samples of power grid monitoring alarm events are used to fine-tune the bidirectional encoder representation from transformer(BERT)model.A mix-training optimization strategy is adopted during fine-tuning to ultimately obtain the power grid monitoring alarm event identification model.Case study results demonstrate that the proposed model in this paper achieves superior identification precision of power grid monitoring alarm events compared to traditional deep learning methods.
摘要With great differences in wind speed changes along the lines of high-speed railways,it cannot meet the operation and maintenance requirements on improving the riding comfort and the efficiency of train operation by using the unified alarm threshold at all wind monitoring points along the entire railway line under the current rules of gale alarm.Based on the historical wind monitoring data collected from multiple high-speed railway lines and combined with the analysis of the alarm mechanism,this paper proposes the methods for improving the gale alarm triggering rules and the time limit threshold for gale alarm release.Verifications are carried out by using the wind monitoring data,which show that the methods proposed achieve the identification of potential short-time strong winds and the adaptive setting of alarm thresholds at wind monitoring points.The methods can further improve the train operation efficiency,alleviate the potential impact of instantaneous strong winds on the stability of train operation,and enjoy a good prospect of application.
基金Foundation items: High-technology Research and Development Programme of China (2007AA03Z544) Aeronautical Science Foundation of China (20075221001)
摘要Multi-functional Al-matrix composites with high volume fraction (55%-57%) of SiC particles are produced with the new pressureless infiltration fabrication technology. X-ray detection and microscopic observation display the composites which are macroscopically homogeneous without porosity. The investigation further reveals that the SiC/Al composites possess low density (2.94 g/cm^3), high elastic modulus (220 GPa), prominent thermal management function as a result of low coefficient of thermal expansion (8 × 10^4 K^-1) and high thermal conductivity (235 W/(m.K)) as well as unique preventability of resonance vibration. By adopting a series of developed techniques, the multi-functional SiC/Al composites have managed to be made into near-net-shape parts. Many kinds of precision components of space-based optomechanical structures and airborne optoelectronic platform have been turned out. Of them, several typical products are being under test in practices.
基金supported by the National Natural Science Foundation of China(21773019,21972012)the Graduate Research and Innovation Foundation of Chongqing(CYB18044)the sharing fund of Chongqing University s Large-scale Equipment
摘要The robust magnesium surfaces with multi-functions are highly desirable,and the simple and scalable methods to construct such surfaces are urgently indispensable.Herein,we conducted a one-step spraying method to facilely fabricate the robust coating with multi-functions on magnesium alloys.The as-sprayed magnesium alloys surface is superhydrophobic with a static water contact angle(WCA)of 157.0°and a roll-off angle of 6.0°.Such surface has excellent mechanical,chemical and thermal stabilities,even undergoing various physical and chemical damages,including sand impact(10 gmin-1,≥20 min),water impact(2 impacts s-1,≥180 min),abrasion(1.00 kPa,≥25 cycles),peeling(≥2.15 kPa),high temperature(200°C,≥24 h),strong acidic/salty/basic media(p H=113)and organic-solvent immersion(ethanol and n-hexane,≥24 h),demonstrating brilliant robustness.Notably,the surface displays multi-functions of corrosion protection,anti-fouling and heat insulation,which will undoubtedly promote the much wider applications of magnesium alloys.
基金supported by the National Natural Science Foundations of China(Nos.5157051626,51475225)
摘要To fulfill the demands for higher quality,efficiency and flexibility in aviation industry,a multi-functional end effector is designed to automate the drilling and riveting processes in assembling carbon fiber reinforced polymer(CFRP)and aluminum components for a robotic aircraft assembly system.To meet the specific functional requirements for blind rivet installation on CFRP and aluminum materials,additional modules are incorporated on the end effector aside of the basic processing modules for drilling.And all of these processing modules allow for a onestep-drilling-countersinking process,hole inspection,automatic rivet feed,rivet geometry check,sealant application,rivet insertion and installation.Besides,to guarantee the better quality of the hole drilled and joints riveted,several online detection and adjustment measures are applied to this end effector,including the reference detection and perpendicular calibration,which could effectively ensure the positioning precision and perpendicular accuracy as demanded.Finally,the test result shows that this end effector is capable of producing each hole to a positioning precision within ±0.5 mm,aperpendicular accuracy within 0.3°,a diameter tolerance of H8,and a countersink depth tolerance of±0.01 mm.Moreover,it could drill and rivet up to three joints per minute,with acceptable shearing and tensile strength.
基金supported by grants from CAMS Innovation Fund for Medical Sciences(Grant No.:2021-I2M-1-026)Scientific Research Project of Tianjin Education Commission(Grant No.:2020KJ140)Tianjin Health Research Project(Grant No.:KJ20017)。
摘要Folate receptor(FR)overexpression occurs in a variety of cancers,including pancreatic cancer.In addition,enhanced macropinocytosis exists in K-Ras mutant pancreatic cancer.Furthermore,the occurrence of intensive desmoplasia causes a hypoxic microenvironment in pancreatic cancer.In this study,a novel FR-directed,macropinocytosis-enhanced,and highly cytotoxic bioconjugate folate(F)-human serum albumin(HSA)-apoprotein of lidamycin(LDP)-active enediyne(AE)derived from lidamycin was designed and prepared.F-HSA-LDP-AE consisted of four moieties:F,HSA,LDP,and AE.F-HSA-LDP presented high binding efficiency with the FR and pancreatic cancer cells.Its uptake in wild-type cells was more extensive than in K-Ras mutant-type cells.By in vivo optical imaging,F-HSA-LDP displayed prominent tumor-specific biodistribution in pancreatic cancer xenograft-bearing mice,showing clear and lasting tumor localization for 360 h.In the MTT assay,F-HSA-LDP-AE demonstrated potent cytotoxicity in three types of pancreatic cancer cell lines.It also induced apoptosis and caused G2/M cell cycle arrest.F-HSALDP-AE markedly suppressed the tumor growth of AsPc-1 pancreatic cancer xenografts in athymic mice.At well-tolerated doses of 0.5 and 1 mg/kg,(i.v.,twice),the inhibition rates were 91.2%and 94.8%,respectively(P<0.01).The results of this study indicate that the F-HSA-LDP multi-functional bioconjugate might be effective for treating K-Ras mutant pancreatic cancer.
基金Project supported by the National Natural Science Foundation of China(Grant No.NSFC 12175107)the Natural Science Foundation of Nanjing Vocational University of Industry Technology,China(Grant No.YK22-02-08)+3 种基金the Qing Lan Project of Jiangsu Province,Chinathe Postgraduate Research&Practice Innovation Program of Jiangsu Province,China(Grant No.KYCX23_0964)the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20230347)the Fund from the Research Center of Industrial Perception and Intelligent Manufacturing Equipment Engineering of Jiangsu Province,China(Grant No.ZK21-05-09)。
摘要Photonic spin Hall effect(PSHE), as a novel physical effect in light–matter interaction, provides an effective metrological method for characterizing the tiny variation in refractive index(RI). In this work, we propose a multi-functional PSHE sensor based on VO2, a material that can reveal the phase transition behavior. By applying thermal control, the mutual transformation into different phase states of VO2 can be realized, which contributes to the flexible switching between multiple RI sensing tasks. When VO2 is insulating, the ultrasensitive detection of glucose concentrations in human blood is achieved. When VO2 is in a mixed phase, the structure can be designed to distinguish between the normal cells and cancer cells through no-label and real-time monitoring. When VO2 is metallic, the proposed PSHE sensor can act as an RI indicator for gas analytes. Compared with other multi-functional sensing devices with the complex structures, our design consists of only one analyte and two VO2 layers, which is very simple and elegant. Therefore, the proposed VO2-based PSHE sensor has outstanding advantages such as small size, high sensitivity, no-label, and real-time detection, providing a new approach for investigating tunable multi-functional sensors.
基金supported by the National Natural Science Foundation of China (No. 61002026)
摘要To cope with the problem of emitter identification caused by the radar words' uncertainty of measured multi-function radar emitters, this paper proposes a new identification method based on stochastic syntax-directed translation schema(SSDTS). This method, which is deduced from the syntactic modeling of multi-function radars, considers the probabilities of radar phrases appearance in different radar modes as well as the probabilities of radar word errors occurrence in different radar phrases. It concludes that the proposed method can not only correct the defective radar words by using the stochastic translation schema, but also identify the real radar phrases and working modes of measured emitters concurrently. Furthermore, a number of simulations are presented to demonstrate the identification capability and adaptability of the SSDTS algorithm.The results show that even under the condition of the defective radar words distorted by noise,the proposed algorithm can infer the phrases, work modes and types of measured emitters correctly.
基金funded by the National Natural Science Foundation of China (No. 32301295 to JW, 32101242 to LM, and 32260253 to LW)High-Level Talents Research Start-Up Project of Hebei University (No. 521100222044 to JW)
摘要Avian alarm calls mediate defenses against brood parasites and predators. These calls facilitate communication among adults and alert nestlings to potential danger. While heterospecific call recognition has been extensively studied in adult birds, nestlings—lacking direct predation experience and heterospecific alarm exposure—represent an ideal system to investigate the response to interspecific warning cues. This study explored the recognition capabilities of 5–6-day-old nestlings in Oriental Reed Warbler (Acrocephalus orientalis), a common host of the Common Cuckoo (Cuculus canorus). We exposed the nestlings to playbacks of alarm calls directed at parasites and raptors from conspecific, Vinous-throated Parrotbill (Sinosuthora webbiana, sympatric species), Isabelline Shrike (Lanius isabellinus, allopatric species) and Common Tailorbird (Orthotomus sutorius, allopatric species) adults. Results indicated that there was no significant difference in the responses of nestlings to the alarm calls of conspecific and allopatric adults directed at cuckoos and sparrowhawks. In addition, interestingly, nestlings significantly reduced their begging in response to conspecific and unfamiliar allopatric Isabelline Shrike and Common Tailorbird alarm calls but exhibited a weak response to the sympatric Vinous-throated Parrotbill. Whether older warbler nestlings with more social experience exhibit stronger responses to the alarm calls of Vinous-throated Parrotbill adults requires further investigation.
基金Project supported by the National Key Research and Development Program of China(Grant No.2016YFB0402504)the National Natural Science Foundation of China(Grant Nos.61875069 and 61575076)+1 种基金Hong Kong Scholars Program,China(Grant No.XJ2016026)the Science and Technology Development Plan of Jilin Province,China(Grant Nos.20190302010GX and 20160520091JH)
摘要We propose a novel and efficient multi-functional optical fiber sensor system based on a dense wavelength division multiplexer(DWDM).This system consists of an optical fiber temperature sensor, an optical fiber strain sensor, and a 48-channel DWDM.This system can monitor temperature and strain changes at the same time.The ranges of these two sensors are from-20℃ to 100℃ and from-1000 με to 2000 με, respectively.The sensitivities of the temperature sensor and strain sensor are 0.03572 nm/℃ and 0.03808 nm/N, respectively.With the aid of a broadband source and spectrometer,different kinds and ranges of parameters in the environment can be monitored by using suitable sensors.
基金National Geographic Society,UCLA(Faculty Senate and the Division of Life Sciences),a Rocky Mountain Biological Laboratory research fellowship,NSF IDBR-0754247,and DEB-1119660 and 1557130 all to D.T.B.DBI-0242960,0731346,1226713,and 1755522 to the RMBL.K.A.was a NSF GRFP fellow during the fnal preparation of this MS。
摘要Emitting alarm calls may be costly,but few studies have asked whether calling increases a caller’s risk of predation and survival.Since observing animals calling and being killed is relatively rare,we capitalized on over 24,000 h of observations of marmot colonies and asked whether variation in the rate that yellow-bellied marmots(Marmota faviventer)alarm called was associated with the probability of summer mortality,a proxy for predation.Using a generalized mixed model that controlled for factors that infuenced the likelihood of survival,we found that marmots who called at higher rates were substantially more likely to die over the summer.Because virtually all summer mortality is due to predation,these results suggest that calling is indeed costly for marmots.Additionally,the results from a Cox survival analysis showed that marmots that called more lived signifcantly shorter lives.Prior studies have shown that marmots reduce the risk by emitting calls only when close to their burrows,but this newly quantifed survival cost suggests a constraint on eliminating risks.Quantifying the cost of alarm calling using a similar approach in other systems will help us better understand its true costs,which is an essential value for theoretical models of calling and social behavior.
基金Funded by the National Natural Science Foundation of China(No.61471024)National Marine Technology Program for Public Welfare,China(No.201505002-1)
摘要A new appraisal method(QDA, quasi-distribution appraisal) which could be used to evaluate the finite element analysis of multi-functional structure made of honeycomb sandwich materials is developed based on sub-section Bezier curve. It is established by simulating the distribution histogram data obtained from the numerical finite element analysis values of a satellite component with sub-section Bezier curve. Being dealt with area normalization method, the simulation curve could be regarded as a kind of probability density function(PDF), its mathematical expectation and the variance could be used to evaluate the result of finite element analysis. Numerical experiments have indicated that the QDA method demonstrates the intrinsic characteristics of the finite element analysis of multi-functional structure made of honeycomb sandwich materials, as an appraisal method, it is effective and feasible.
基金supported by the National Natural Science Foundation of China (Nos. 21371069 and 21621001)
摘要Metal-organic frameworks(MOFs) are a unique class of porous crystalline materials that have shown promise for a wide range of applications. MOFs have been explored as a new type of heterogeneous catalytic materials, because of their high surface area, uniform and tunable pores, facile functionalization and incorporation of catalytic active sites. The use of multi-functional sites MOF materials as catalysts for synergistic catalysis and tandem reactions has attracted increasing attention. In this review, we aim to introduce the construction of bi-or multi-functional MOF catalysts with cooperative or cascade functions via post-synthetic modification(PSM).
基金supported by the National Natural Science Foundation of China(Grants U23A20660,52008099,and 52378288)the Major Science and Technology Project of Yunnan Province,China(Grant 202502AD080007)the China Railway Engineering Corporation Science and Technology Research and Development Project(Grant 2022-Key-44).
摘要There are multiple types of risks involved in the service of long-span railway bridges.Classical methods are difficult to provide targeted alarm information according to different situations of load anomalies and structural anomalies.To accurately alarm different risks of long-span railway bridges by structural health monitoring systems,this paper proposes a cross-cooperative alarm method using principal and secondary indicators during high-wind periods.It provides the prior criterion for monitoring systems under special conditions,defining the principal and secondary indicators,alarm levels,and thresholds based on the relationship between dynamic equilibrium equations and multiple linear regression analysis.Analysis of one-year monitoring data from a longspan railway cable-stayed bridge shows that the 10-min average cross-bridge wind speed(excitation indicator)can be selected as the principal indicator,while lateral displacement(response indicator)can serve as the secondary indicator.The threshold levels of the secondary indicator prioritize the safety of bridge operation(mainly aiming at the safety of trains traversing bridges),with values significantly lower than structural safety thresholds.This approach enhances alarm timeliness and effectively distinguishes between load anomalies,structural anomalies,and equipment failures.Consequently,it improves alarm accuracy and provides timely decision support for bridge maintenance,train traversing,and emergency treatment.
基金upported by the National Natural Science Foundation of China(No.21875226)the Science Fund for Distinguished Young Scholars of Sichuan Province(No.2017JQ0036)the Chengdu Rongpiao Talent plan,the Sichuan'Ten-thousand Talents Program",the"QianYingBaiTuan"Plan of China Mianyang Science City,the Science Foundation of Institute of Chemical Materials(No.O11100301)the"Global Experts Recruitment"program.
摘要Fiber-shaped supercapacitors(FSSCs)show great potential in portable and wearable electronics due to their unique advantages of high safety,environmental friendliness,high performances,outstanding flexibility and integrability.They can directly act as the power sources or be easily integrated with other flexible devices to constitute self-powered and sustainable energy suppliers,providing excellent adaptability to irregular surfaces.This review mainly summarizes the recently reported works of FSSCs including preparation methods of various fiber electrodes,construction strategies of FSSCs and multi-functional device integrations,exploration of reaction mechanisms and strategies to improve the electrochemical performance and provision of suggestions on further designing and optimization of FSSCs.Meanwhile,it shares our perspectives on challenges and opportunities in this field,shedding light on the development of high-performance fiber-shaped supercapacitors with multifunctions.
摘要Calcium is a critical second messenger molecule in all cells and is vital in neurons for synaptic transmission.Given this importance,calcium ions are tightly controlled by a host of molecular players including ion channels,sensors,and buffering proteins.Calcium can act directly by binding to signaling molecules or calcium’s effects can be indirect,for example by altering nuclear histones.
基金funded by the Education Department of Hainan Province(no.HnjgY 2022-12)the National Natural Science Foundation of China(no.32260127).
摘要Alarm calls in bird vocalizations serve as acoustic signals announcing danger.Owing to the convergent evolution of alarm calls,some bird species can beneft from eavesdropping on certain parameters of alarm calls of other species.Vocal mimicry,displayed by many bird species,aids defense against predators and may help brood parasites during parasitism.In the coevolutionary dynamics between brood parasites,such as the common cuckoo(Cuculus canorus),and their hosts,female cuckoo vocalizations can induce hosts to leave the nest,increasing the probability of successful parasitism and reducing the risk of host attacks.Such cuckoo calls were thought to mimic those of the sparrowhawk.However,owing to their similarity to alarm calls,we propose a new hypothesis:Female cuckoos cheat their hosts by mimicking the parameters of the host alarm call.In this study,we tested this new hypothesis and the sparrowhawk mimicry hypothesis simultaneously by manipulating the syllable rate in male and female common cuckoo vocalizations and playing them in front of the host Oriental reed warbler(Acrocephalus orientalis)for examination.The results indicate that similar to a normal female cuckoo call,a female call with a reduced syllable rate prompted the hosts to leave their nests more frequently and rapidly than male cuckoo calls.Additionally,the male cuckoo calls with increased syllable rate did not prompt the host to leave their nests more frequently or quickly compared with the male cuckoo calls with a normal syllable rate.Our results further confrm that female common cuckoos mimic the vocalizations of Eurasian sparrowhawks(Accipiter nisus),reveal the function mechanisms underlying such mimicry,and support the theory of imperfect mimicry.