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Chinese herbal medicine for colorectal cancer:An overview of systematic reviews and evidence map 认领 引用
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作者 He-Ping Wang Xiao-Yan Qin +4 位作者 Bo-Wen Xu Tai-Cheng Lu Rui-Ke Gao Ming Lin Jie Li 《World Journal of Gastrointestinal Oncology》 SCIE 2026年第7期346-361,共16页
BACKGROUND Colorectal cancer(CRC)accounts for second place of new cases in China.Chinese herbal medicine(CHM)is widely used as an integrative treatment for CRC.However,evidence on the efficacy of CHM for CRC remains u... BACKGROUND Colorectal cancer(CRC)accounts for second place of new cases in China.Chinese herbal medicine(CHM)is widely used as an integrative treatment for CRC.However,evidence on the efficacy of CHM for CRC remains unclear.AIM To evaluate quality of previous systematic reviews(SRs)and summarise evidence on CHM treatment for CRC.METHODS All available online academic databases were systematically searched from the time of their foundation to October 2025,and eligible systematic reviews investigating therapeutic effectiveness and safety of CHM in the treatment of CRC patients were incorporated into this study.Their reporting,methodological and evidence quality were evaluated using the PRISMA,AMSTAR-2,and GRADE.RESULTS Ninety-seven SRs were included in this study.Thirty of the included SRs were assessed as high in reporting quality,67 as moderate;12 SRs were assessed as moderate in methodological quality,27 as low quality,58 as critically low quality.Seven pieces of evidence assessed as moderate quality by GRADE approach,40 as low quality,and 46 as very low quality.Moderate-quality evidence showed that orally administered CHM plus XELOX increased the objective response rate(ORR)by 44%.Compound Kushen Injection plus FOLFOX increased ORR by 26%and Karnofsky Performance Status(KPS)improvement rate by 24%.Aidi Injection plus FOLFOX4 chemotherapy increased ORR by 22%,disease control rate by 10%and KPS improvement rate by 30%.CONCLUSION Orally administered CHM and CHM injections combined with chemotherapy have promising effects on tumor response and performance status of patients with advanced CRC. 展开更多
关键词 Chinese herbal medicine Colorectal cancer Randomized controlled trial Evidence map Overview of reviews Meta-analysis
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Correction:M apping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview 认领 引用
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作者 Yi-Ping Wu Lu-Da Feng +5 位作者 Yun Zhao Man-Rui Wang Jia-You Liu Bo-Yang Li Bo-Ya Zhang Jian-Guo Qin 《Medical Data Mining》 CAS 2026年第1期59-60,共2页
Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proo... Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proof on 28 September 2025 without any questions.However,on 13 November 2025,the Editorial Office of Medical Data Mining noticed an inconsistency between the data presented in the main text and Figure 1.Specifically,erroneous Figure 1 states“a total of 56,691 literatures were obtained through database search”,while the main text in the Search results section states“According to the search term,a total of 59,220 publications were retrieved from the database.”The authors acknowledge that the original version of Figure 1 was incorrect and have provided the revised,correct version in this corrigendum.The authors would like to assert that there is no change in the body text of the article. 展开更多
关键词 hotspots global research trends hotspots data mining bibliometrics overview research trends hypertensive nephropathy medical data mining bibliometrics
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An Overview and Pathway Exploration of the Inheritance and Development of Traditional Chinese Medicine in Zhaotong Region from the Perspective of Cultural Confidence 认领 引用
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作者 Changxing Huang Juncheng Liu +4 位作者 Xinglian Gao Zeying Zhao Fu Li Bo Yang Heguo Yan 《Journal of Contemporary Educational Research》 2026年第3期6-16,共11页
Traditional Chinese medicine(TCM),as a treasure of the Chinese nation,embodies the profound essence of traditional Chinese culture.It serves as a vital component and carrier of this heritage,forming a solid foundation... Traditional Chinese medicine(TCM),as a treasure of the Chinese nation,embodies the profound essence of traditional Chinese culture.It serves as a vital component and carrier of this heritage,forming a solid foundation for upholding cultural confidence in TCM.As one of Yunnan’s three major cultural cradles,Zhaotong boasts a rich accumulation of TCM culture,constituting an integral part of southern Yunnan’s medical tradition.Therefore,this paper aims to examine the development of TCM in the Zhaotong region,interpret its distinctive advantages and existing challenges,and explore potential development pathways.This effort seeks to foster a unique sense of cultural value recognition for TCM in Zhaotong and promote the inheritance and advancement of TCM within the region. 展开更多
关键词 Cultural confidence Zhaotong region Traditional Chinese medicine Development overview Pathways
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An Optimized Teaching Approach of the Course Overview of Arab Countries in a Multimodal Interactive Environment 认领 引用
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作者 QI Ji 《US-China Education Review(A)》 2025年第5期336-339,共4页
Against the backdrop of educational digital transformation,multimodal interactive teaching offers a new paradigm for the reform of area studies courses.Using the course Overview of Arab Countries as a case study,this ... Against the backdrop of educational digital transformation,multimodal interactive teaching offers a new paradigm for the reform of area studies courses.Using the course Overview of Arab Countries as a case study,this research addresses key challenges in traditional teaching approaches,such as weak cultural awareness,low student engagement,and limited cross-cultural communication skills.It proposes an optimized multimodal teaching framework based on the integration of three core components:content,methodology,and assessment,aiming to create a more dynamic and student-centered learning environment.Through the strategic use of digital resources,interactive technologies,and diversified assessment methods,the study demonstrates that multimodal interaction effectively stimulates students’learning interest,enhances their language proficiency,fosters critical thinking,and promotes deeper knowledge acquisition and competence transformation.The findings suggest that multimodal interactive teaching can significantly improve the overall effectiveness of area studies education,providing valuable insights for future pedagogical innovations in the digital era. 展开更多
关键词 multimodal interaction Overview of Arab Countries instructional pathway effectiveness evaluation
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Application of Artificial Intelligence in Medicine: An Overview 认领 引用 被引量：43
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作者 Peng-ran LIU Lin LU +3 位作者 Jia-yao ZHANG Tong-tong HUO Song-xiang LIU Zhe-wei YE 《Current Medical Science》 SCIE CAS 2021年第6期1105-1115,共11页
Artificial intelligence(AI)is a new technical discipline that uses computer technology to research and develop the theory,method,technique,and application system for the simulation,extension,and expansion of human int... Artificial intelligence(AI)is a new technical discipline that uses computer technology to research and develop the theory,method,technique,and application system for the simulation,extension,and expansion of human intelligence.With the assistance of new AI technology,the traditional medical environment has changed a lot.For example,a patient’s diagnosis based on radiological,pathological,endoscopic,ultrasonographic,and biochemical examinations has been effectively promoted with a higher accuracy and a lower human workload.The medical treatments during the perioperative period,including the preoperative preparation,surgical period,and postoperative recovery period,have been significantly enhanced with better surgical effects.In addition,AI technology has also played a crucial role in medical drug production,medical management,and medical education,taking them into a new direction.The purpose of this review is to introduce the application of AI in medicine and to provide an outiook of future trends. 展开更多
关键词 artificial intelligence medicine application overview
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大豆株高QTL的“整合”及Overview分析 认领 引用 被引量：17
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作者 高利芳 郭勇 +1 位作者 郝再彬 邱丽娟 《遗传》 CAS CSCD 北大核心 2013年第2期215-224,共10页
株高是作物株型的重要组成因子,与作物种植密度、抗倒伏性及产量等密切相关。文章利用Soybase数据库和文献报道的201个与大豆株高相关的QTL信息,在物理整合的基础上,采用软件BioMercator2.1进行元分析,得到15个株高的"通用"Q... 株高是作物株型的重要组成因子,与作物种植密度、抗倒伏性及产量等密切相关。文章利用Soybase数据库和文献报道的201个与大豆株高相关的QTL信息,在物理整合的基础上,采用软件BioMercator2.1进行元分析,得到15个株高的"通用"QTL,分别位于大豆的6号、7号、11号、13号和18号染色体。同时,利用基于统计学原理的Overview方法进行优化,将这些QTL位点的置信区间最小缩至0.1 cM,从而明确了QTL位点在染色体上的遗传位置。对重演性较好的QTL位点所对应的区段内的基因进行分析,初步筛选出可能与株高相关的候选基因17个。文章为大豆株高相关QTL位点的精细定位及分子标记辅助育种奠定了基础。 展开更多
关键词 大豆 株高 元分析 Overview分析
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基于Overview和物理图谱的大豆株高性状候选基因挖掘 认领 引用 被引量：5
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作者 尹振功 王强 +3 位作者 孟宪欣 刘广阳 郭怡璠 王秀君 《大豆科学》 CAS CSCD 北大核心 2019年第6期914-920,共7页
为更加准确地挖掘大豆株高性状候选基因,本研究利用已有研究中与大豆株高性状相关的249个QTL位点,以大豆基因组物理图谱为背景进行整合,并通过Overview分析得到32个重演性较好的置信区间,分布在大豆D1b、N、C1、A1、C2、M、K、O、B1、F... 为更加准确地挖掘大豆株高性状候选基因,本研究利用已有研究中与大豆株高性状相关的249个QTL位点,以大豆基因组物理图谱为背景进行整合,并通过Overview分析得到32个重演性较好的置信区间,分布在大豆D1b、N、C1、A1、C2、M、K、O、B1、F、J、D2、G和L连锁群上,其中D1b、A1、C2、M、F、L连锁群的重演性较好的置信区间较多。对候选区段进行基因注释,分析得出植物激素信号转导通路(ID:Ko04075)可能为大豆株高调控的主要通路,该通路与植物细胞增大、分化、茎生长、休眠、果实成熟和抗逆性等植物生理过程紧密相关。通路中13个候选基因与大豆株高性状相关,9个基因被注释为编码生长素响应蛋白,3个基因被注释为编码脱落酸相关蛋白,1个基因为GH3生长素响应启动子。本研究为挖掘大豆株型性状候选基因、构建大豆理想株型和促进分子辅助育种提供新思路。 展开更多
关键词 大豆 物理图谱 Overview 株高 基因挖掘
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Effectiveness and safety of acupuncture for treating functional constipation: An overview of systematic reviews 认领 引用 被引量：9
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作者 Jun-peng Yao Li-ping Chen +7 位作者 Xian-jun Xiao Ting-hui Hou Si-yuan Zhou Ming-min Xu Kai Wang Yu-jun Hou Lin Zhang Ying Li 《Journal of Integrative Medicine》 SCIE CAS CSCD 2022年第1期13-25,共13页
Background: Functional constipation(FC) is one of the most prevalent functional gastrointestinal disorders. Dissatisfaction with medications prescribed to treat FC may lead patients to seek alternative treatments. Num... Background: Functional constipation(FC) is one of the most prevalent functional gastrointestinal disorders. Dissatisfaction with medications prescribed to treat FC may lead patients to seek alternative treatments. Numerous systematic reviews(SRs) examining the use of acupuncture to treat FC have reported inconsistent results, and the quality of these studies has not been fully evaluated.Objective: In this overview, we evaluated and summarized clinical evidence on the effectiveness and safety of acupuncture for treating FC and evaluated the quality and bias of the SRs we reviewed.Search strategy: The search strategy was structured by medical subject headings and search terms such as‘‘acupuncture therapy" and ‘‘functional constipation." Electronic searches were conducted in eight databases from their inception to September 2020.Inclusion criteria: SRs that investigated the effectiveness and safety of acupuncture for managing FC were included.Data extraction and analysis: Two authors independently extracted information and appraised the methodology, reporting accuracy, quality of evidence, and risk of bias using the following critical appraisal tools:(1) A Measurement Tool to Assess Systematic Reviews 2(AMSTAR 2);(2) Risk of Bias in Systematic Reviews(ROBIS);(3) Preferred Reporting Items for Systematic Reviews and Meta-analyses for Acupuncture(PRISMA-A);and(4) the Grading of Recommendations, Assessment, Development and Evaluations(GRADE). A j index was used to score the level of agreement between the 2 reviewers.Results: Thirteen SRs that examined the clinical utility of acupuncture for treating FC were identified.Using the AMSTAR 2 tool, we rated 92.3%(12/13) of the SRs as ‘‘critically low" confidence and one study as ‘‘low" confidence. Using the ROBIS criteria, 38.5%(5/13) of the SRs were considered to have ‘‘low risk"of bias. Based on PRISMA-A, 76.9%(10/13) of the SRs had over 70% compliance with reporting standards.The inter-rater agreement was good for AMSTAR 2, ROBIS, and PRISMA-A. Using the GRADE tool, we classified 22.5%(9/40) of the measured outcomes as ‘‘moderate" quality, 57.5%(23/40) as ‘‘low" quality, and 20.0%(8/40) as ‘‘very low" quality. The inter-rater agreement was moderate when using GRADE.Descriptive analyses indicated that acupuncture was more efficacious than sham acupuncture for improving weekly complete spontaneous bowel movements(CSBMs) and for raising the Bristol Stool Form Scale(BSFS) score. Acupuncture appeared to be superior to anti-constipation drugs for improving weekly spontaneous bowel movements, the total effective rate, and the Patient Assessment of Constipation Quality of Life score. Although ten SRs mentioned the occurrence of adverse events, serious adverse events were not associated with acupuncture treatment.Conclusion: Acupuncture may be more efficacious than sham acupuncture for improving CSBMs and BSFS scores and may be superior to anti-constipation drugs for improving bowel movement frequency, as well as quality of life. Limitations to current studies and inconsistent evidence suggest a need for more rigorous and methodologically sound SRs to draw definitive conclusions. 展开更多
关键词 Functional constipation Acupuncture Overview Systematic review Meta-analysis
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大豆倒伏性相关QTL的整合及Overview分析 认领 引用 被引量：8
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作者 刘硕 郭勇 +1 位作者 罗玲 邱丽娟 《植物遗传资源学报》 CAS CSCD 北大核心 2014年第1期137-143,共7页
倒伏性是影响大豆产量的重要因素,发掘与大豆倒伏相关的基因对于培育抗倒伏优良高产大豆品种具有重要意义。目前利用不同群体所构建的遗传图谱已经定位了大量与大豆倒伏性相关的QTLs。本研究在对已报道的QTLs进行物理整合的基础上,选择... 倒伏性是影响大豆产量的重要因素,发掘与大豆倒伏相关的基因对于培育抗倒伏优良高产大豆品种具有重要意义。目前利用不同群体所构建的遗传图谱已经定位了大量与大豆倒伏性相关的QTLs。本研究在对已报道的QTLs进行物理整合的基础上,选择元分析方法将这些倒伏性相关的QTLs进一步整合,鉴定出位于C2(6号染色体)、F(13号染色体)、L(19号染色体)这3个连锁群上重复次数较多的QTL区间6个。选用基于统计学原理的Overview方法进行优化,获得了这些QTL在各个连锁群上的有效遗传位置,这些QTL的置信区间长度最小可缩至0.2 cM。通过在这些区间内进一步筛选,获得一个稳定性较好的标记Satt277。本研究可为大豆抗倒伏基因发掘及分子标记辅助选择育种提供理论依据。 展开更多
关键词 大豆 倒伏性 物理整合 元分析 Overview分析
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Overview of the systematic reviews of premature ovarian insufficiency treated with acupuncture 认领 引用 被引量：7
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作者 Xue CAO Ming-lin SUN +5 位作者 Yu-ning QIN Jia-jia ZHANG Yi-fan BAI Yan ZHANG Yan-ke AI Jia LIU 《World Journal of Acupuncture-Moxibustion》 CAS CSCD 2022年第4期287-297,共11页
Objective:To assess the reliability of the methodological quality and outcome measures of systematic reviews(SR)/meta-analysis of premature ovarian insufficiency(POI) treated with acupuncture.Methods:SR/meta-analysis ... Objective:To assess the reliability of the methodological quality and outcome measures of systematic reviews(SR)/meta-analysis of premature ovarian insufficiency(POI) treated with acupuncture.Methods:SR/meta-analysis of POI treated with acupuncture were searched on POI from the databases including PubMed,Web of Science,EMBase,the Cochran Library,Chinese biomedical literature database(SinoMed),China journal full-text database(CNKI),Wanfang data knowledge service platform(Wanfang)and VIP information Chinese periodical service platform(VIP),from inception to 1 st May 2021.Using A Measurement Tool to Assess Systematic Reviews 2(AMSTAR 2) scale and Grades of Recommendations Assessment,Development and Evaluation(GRADE) system,the methodological quality and outcome measures of the included studies were appraised.Results:Ten articles of SR/meta-analysis were included,published from 2015 to 2020.Using AMSTAR 2,5 articles of SR/meta-analysis were rated as critical low quality in methods,3 articles as low quality,and2 articles as moderate quality.The results of GRADE showed that among the 50 outcomes the quality of evidence of 22 outcomes was very low,that of 25 outcomes was low and that of 3 outcomes was moderate.Conclusion:The methodological quality and the reliability of outcome measures were not high in existing SR/meta-analysis on POI treated with acupuncture,which may affect the translation of the SR/metaanalysis findings into clinical practice.It is necessary to further strengthen the methodological quality and reporting standard of SR/meta-analysis,as well as the robustness of design and implementation of randomized controlled trials(RCTs),in order to generate high quality evidences for clinical decision-making and practice. 展开更多
关键词 Acupuncture Premature ovarian insufficiency Overview of systematic reviews AMSTAR 2 GRADE system
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大豆蛋白质含量QTL的“整合”及Overview分析 认领 引用 被引量：15
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作者 刘硕 罗玲 +2 位作者 刘章雄 关荣霞 邱丽娟 《大豆科学》 CAS CSCD 北大核心 2011年第1期1-7,14,共7页
在物理整合的基础上,选用元分析方法将已发表的与蛋白质相关的QTL整合到物理整合中重复次数较多的6个QTL区间处,并且选用基于统计学原理的Overview方法进行优化,得到连锁群上QTL的有效遗传位置,最终筛选出稳定性较强的标记Satt127,研究... 在物理整合的基础上,选用元分析方法将已发表的与蛋白质相关的QTL整合到物理整合中重复次数较多的6个QTL区间处,并且选用基于统计学原理的Overview方法进行优化,得到连锁群上QTL的有效遗传位置,最终筛选出稳定性较强的标记Satt127,研究结果为标记辅助鉴定提供了理论依据。 展开更多
关键词 大豆 蛋白质 物理整合 元分析 Overview 优化
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Deep learning based point cloud registration:an overview 认领 引用 被引量：17
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作者 Zhiyuan ZHANG Yuchao DAI Jiadai SUN 《虚拟现实与智能硬件（中英文）》 EI 2020年第3期222-246,共25页
Point cloud registration aims to find a rigid transformation for aligning one point cloud to another.Such registration is a fundamental problem in computer vision and robotics,and has been widely used in various appli... Point cloud registration aims to find a rigid transformation for aligning one point cloud to another.Such registration is a fundamental problem in computer vision and robotics,and has been widely used in various applications,including 3D reconstruction,simultaneous localization and mapping,and autonomous driving.Over the last decades,numerous researchers have devoted themselves to tackling this challenging problem.The success of deep learning in high-level vision tasks has recently been extended to different geometric vision tasks.Various types of deep learning based point cloud registration methods have been proposed to exploit different aspects of the problem.However,a comprehensive overview of these approaches remains missing.To this end,in this paper,we summarize the recent progress in this area and present a comprehensive overview regarding deep learning based point cloud registration.We classify the popular approaches into different categories such as correspondences-based and correspondences-free approaches,with effective modules,i.e.,feature extractor,matching,outlier rejection,and motion estimation modules.Furthermore,we discuss the merits and demerits of such approaches in detail.Finally,we provide a systematic and compact framework for currently proposed methods and discuss directions of future research. 展开更多
关键词 Overview Point cloud registration Deep learning Graph neural networks
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Chinese herbal medicine combined with Western medicine for Mycoplasma pneumoniae pneumonia in children:An overview of systematic reviews 认领 引用 被引量：5
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作者 Si Zhang Xuan Zhang +4 位作者 Yuehua Cui Juan Huang Fei Fan Simeng Wang Fei Han 《Journal of Traditional Chinese Medical Sciences》 CAS 2024年第1期131-139,共9页
Objective:To summarize the characteristics and evaluate the quality of the methodology and evidence within systematic reviews(SRs)of Chinese herbal medicine(CHM)for Mycoplasma pneumoniae pneumonia(MPP)inchildren.Metho... Objective:To summarize the characteristics and evaluate the quality of the methodology and evidence within systematic reviews(SRs)of Chinese herbal medicine(CHM)for Mycoplasma pneumoniae pneumonia(MPP)inchildren.Methods:SRs of randomized controlled trials were searched using PubMed,the Cochrane Library,Embase,the Chinese National Knowledge Infrastructure Databases(CNKI),the Chinese Scientific Journals Database(VIP),Wanfang,and the SinoMed Database.SRs on the use of CHM alone or in combination with Western medications for MPP in children were included.The study compared the effects of Western medicine alone with those of CHM.The evidence quality using the A Measurement Tool to Assess Systematic Reviews(AMSTAR)2,the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)2020,and the Grading of Recommendations,Assessment,Development,and Evaluation(GRADE)criteria.The primary indicators were the total effective rate,fever subsidence time,and cough disappearance time.The secondary outcomes were pulmonary rale disappearance time,average hospitalization time,lung X-ray infiltrate disappearance time,immunological indices,and inflammatory cytokine levels.Results:Twelve relevant SRs were included;75%(9/12)were assessed as very low quality,and 25%(3/12)Were rated as low quality using the AMSTAR 2 criteria.According to the PRISMA 2020 checklist,the average SR score was 20.3 out of a 27 point maximum.In all SRs,CHM demonstrated improvement in symptoms and signs among children with MPP.The evidence quality using the GRADE criteria ranged from"very low"(>50%)to"moderate"(<5%).The most common downgrading factor was imprecision,followed by publication bias and inconsistency.Conclusion:This overview highlights the limited quality of the methodology and evidence of the included SRs.Although the included studies showed the beneficial effects of CHM on MPP in children,it was difficult to draw firm conclusions owing to methodological flaws. 展开更多
关键词 Chinese herbal medicine Mycoplasma pneumoniae pneumonia Children Overview Systematic review
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基于Overview和物理图谱的大豆主茎节数候选基因挖掘 认领 引用 被引量：2
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作者 尹振功 王强 +5 位作者 孟宪欣 刘广阳 郭怡璠 王秀君 魏淑红 来永才 《大豆科学》 CAS CSCD 北大核心 2020年第3期370-376,共7页
利用与大豆主茎节数性状相关的54个原始QTL位点,应用Overview方法首次以大豆参考基因组物理图谱为背景进行整合和分析,得到11个重演性较好的置信区间,分布在大豆D1b、C2、B1、F、L和I连锁群上,其中L连锁群重演性较好的置信区间较多。对... 利用与大豆主茎节数性状相关的54个原始QTL位点,应用Overview方法首次以大豆参考基因组物理图谱为背景进行整合和分析,得到11个重演性较好的置信区间,分布在大豆D1b、C2、B1、F、L和I连锁群上,其中L连锁群重演性较好的置信区间较多。对得到的候选区段进行基因注释得到488个候选基因,其中Glyma.11G087300、Glyma.20G014300、Glyma.13G221400、Glyma.06G243500、Glyma.13G052900、Glyma.13G052700参与植物激素信号转到通路(ID:Ko04075),推测这6个基因通过该通路的赤霉素途径和生长素途径参与大豆主茎节数的遗传调控。本研究所挖掘到的与茎生长发育及主茎节数直接相关的通路和候选基因能够为构建理想株型和大豆分子辅助育种提供新思路。 展开更多
关键词 大豆 主茎节数 QTL Overview 候选基因
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Chinese medicine formulas for nonalcoholic fatty liver disease: Overview of systematic reviews 认领 引用 被引量：5
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作者 Liang Dai Wen-Jun Zhou +2 位作者 Linda L D Zhong Xu-Dong Tang Guang Ji 《World Journal of Clinical Cases》 SCIE 2021年第1期102-117,共16页
BACKGROUND Nonalcoholic fatty liver disease(NAFLD)affects more than one-quarter of the global population.Due to the lack of approved chemical agents,many patients seek treatment from traditional Chinese medicine(TCM)f... BACKGROUND Nonalcoholic fatty liver disease(NAFLD)affects more than one-quarter of the global population.Due to the lack of approved chemical agents,many patients seek treatment from traditional Chinese medicine(TCM)formulas.A variety of systematic reviews have been published regarding the effectiveness and safety of TCM formulas for NAFLD.AIM To critically appraise available systematic reviews and sort out the high-quality evidence on TCM formulas for the management of NAFLD.METHODS Seven databases were systematically searched from their inception to 28 February 2020.The search terms included“non-alcoholic fatty liver disease,”“Chinese medicines,”“systematic review,”and their synonyms.Systematic reviews involving TCM formulas alone or in combination with conventional medications were included.The methodological quality and risk of bias of eligible systematic reviews were evaluated by using A Measure Tool to Assess Systematic Reviews 2(AMSTAR 2)and Risk of Bias in Systematic Review(ROBIS).The quality of outcomes was assessed by the Grading of Recommendations Assessment,Development and Evaluation(GRADE)system.RESULTS Seven systematic reviews were ultimately included.All systematic reviews were conducted based on randomized controlled trials and published in the last decade.According to the AMSTAR 2 tool,one systematic review was judged as having a moderate confidence level,whereas the other studies were rated as having a low or extremely low level of confidence.The ROBIS tool showed that the included systematic reviews all had a high risk of bias due to insufficient consideration of identified concerns.According to the GRADE system,only two outcomes were determined as high quality;namely,TCM formulas with the HuoXueHuaYu principle were better than conventional medications in ultrasound improvement,and TCM formulas were superior to antioxidants in alanine aminotransferase normalization.Other outcomes were downgraded to lower levels,mainly because of heterogeneity among studies,not meeting optimal information sample size,and inclusion of excessive numbers of small sample studies.Nevertheless,the evidence quality of extracted outcomes should be further downgraded when applying to clinical practice due to indirectness.CONCLUSION The quality of available systematic reviews was not satisfactory.Researchers should avoid repeatedly conducting systematic reviews in this area and focus on designing rigorous randomized controlled trials to support TCM formula applications. 展开更多
关键词 Nonalcoholic fatty liver disease Traditional Chinese medicines Systematic review Meta-analysis Overview Grading of recommendations assessment,development and evaluation system
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Overview of Permanent-Magnet Fault-Tolerant Machines: Topology and Design 认领 引用 被引量：11
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作者 Wenxiang Zhao Liang Xu Guohai Liu 《CES Transactions on Electrical Machines and Systems》 CSCD 2018年第1期51-64,共14页
Permanent-magnet(PM)machines have attracted a lot of interest in various applications since they have the merits of high torque density,high power density and high efficiency.However,issue of poor fault tolerance of t... Permanent-magnet(PM)machines have attracted a lot of interest in various applications since they have the merits of high torque density,high power density and high efficiency.However,issue of poor fault tolerance of the conventional PM machines restricts their practical applications in the field of safety-critical applications,e.g.aerospace,electric vehicle,electrical propulsion and wind power generator applications.An enormous amount of work has been done to improve the fault-tolerant capability of PM machines.This paper will review research work on PM fault-tolerant machines up-to-date,including modular design,short-circuit current limitation design,redundant design,ease of thermal dissipation of PM design,and torque enhancement design techniques.The work of this paper can provide some references for future studies and engineering applications of PM fault-tolerant machines for safety-critical applications. 展开更多
关键词 Fault-tolerant machine modular overview permanent-magnet machine torque
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激光共聚焦显微镜的Overview功能应用于古气候纹层学的扫描技巧 认领 引用 被引量：2
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作者 曲晓丽 朱楠 +2 位作者 王鑫垚 赵景耀 董西瑀 《电子显微学报》 CAS CSCD 北大核心 2021年第3期265-269,共5页
激光扫描共聚焦显微镜(laser scanning confocal microscope,LSCM)的Overview功能,即对大视野的总览扫描,可以对视野的不同位置进行分别定焦,在扫描大图像过程中实现对焦面变化的平滑过渡,得到聚焦准确、亮度均衡的完整大图像。为了推广... 激光扫描共聚焦显微镜(laser scanning confocal microscope,LSCM)的Overview功能,即对大视野的总览扫描,可以对视野的不同位置进行分别定焦,在扫描大图像过程中实现对焦面变化的平滑过渡,得到聚焦准确、亮度均衡的完整大图像。为了推广LSCM在古气候纹层学的应用,本文以古气候学研究载体-石笋为例,使用Nikon A1的Overview功能,通过LSCM软件功能的灵活运用,实现了其荧光微层的大视野扫描成像,为古气候纹层学的进一步发展提供支持。 展开更多
关键词 激光共聚焦显微镜 Overview功能 古气候纹层学 大图像
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Common traditional Chinese medicine therapies for diarrhea-predominant irritable bowel syndrome: An overview of systematic reviews 认领 引用 被引量：2
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作者 Jun Zhao Xia Li +7 位作者 Xiaowei Chen Hui Zheng Kun Ye Yunzhou Shi Xin Xie Jianfang Wang Min Chen Zhigang Li 《Journal of Traditional Chinese Medical Sciences》 CAS 2022年第3期330-339,共10页
Objective: To critically evaluate and summarize the methodological quality of systematic reviews(SRs)and present objective and important outcomes on the effectiveness of traditional Chinese medicine(TCM) therapies, in... Objective: To critically evaluate and summarize the methodological quality of systematic reviews(SRs)and present objective and important outcomes on the effectiveness of traditional Chinese medicine(TCM) therapies, including Chinese herbal medicine(CHM), acupuncture, and moxibustion, for diarrheapredominant irritable bowel syndrome(IBS-D).Methods: We conducted a comprehensive literature search for SRs in 7 databases until April 16, 2022.Two reviewers independently extracted data and assessed the methodological quality of the reviews according to the Assessing the Methodological Quality of Systematic Reviews 2(AMSTAR-2), the Risk of Bias in Systematic reviews(ROBIS) tool, and the Preferred Reporting Item for Systematic Review and Meta-analysis(PRISMA) statement. The Grading of Recommendations, Assessment, Development, and Evaluation(GRADE) was used to rate the quality of evidence.Results: IBS-D patients included in 12 reviews were diagnosed in accordance with the Rome criteria, 9 reviews focused on CHM, 2 articles observed moxibustion and heat-sensitive moxibustion, 1 article studied acupuncture and CHM. The outcomes of the SRs were the effectiveness rate, the total effectiveness rate,global symptom improvement, and adverse effects. Based on AMSTAR-2, which measures the quality of methodology, all of the included studies were of low or critically low quality. According to the ROBIS tool, 10 SRs(83.33%) had a high risk of bias. With the PRISMA checklist, only 3 SRs reached over 90% compliance.Based on GRADE, most evidence was of low quality, and there was a moderate quality of evidence that the effectiveness rate of modified-Tongxie Yaofang was superior to Western medicine in the treatment of IBS-D.Conclusion: Given the suboptimal reporting and methodological quality of existing SRs, more studies are needed to clarify whether TCM therapies are more effective or safe than pharmacological medicine.Future studies should combine evidence-based medicine with TCM research according to the characteristics of TCM. 展开更多
关键词 Diarrhea-predominant irritable bowel syndrome Overview Traditional Chinese medicine therapies AMSTAR-2 GRADE PRISMA ROBIS
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Overview of Molecular Typing Tools for The Characterization of Salmonella enterica in Malaysia 认领 引用 被引量：2
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作者 Soo Tein Ngoi Cindy Shuan Ju Teh +1 位作者 Lay Ching Chai Kwai Lin Thong 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2015年第10期751-764,共14页
Salmonella is a member of the family Enterobacteriaceae. This genus comprises two species, namely Salmonella enterica and Salmonella bongori. Salmonella enterica is further divided into six subspecies, namely enterica... Salmonella is a member of the family Enterobacteriaceae. This genus comprises two species, namely Salmonella enterica and Salmonella bongori. Salmonella enterica is further divided into six subspecies, namely enterica, salamae, arizonae, 展开更多
关键词 Overview of Molecular Typing Tools for The Characterization of Salmonella enterica in Malaysia PFGE MLVA PCR
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Research overview of profile control and water shut-off agents for heavy oil thermal recovery 认领 引用 被引量：1
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作者 ZHAO Xiu-tai FU Min-jie +2 位作者 WANG Zeng-bao DONG Lin-yan TANG Jin-yu 《特种油气藏》 CAS CSCD 北大核心 2013年第4期I0001-I0008,共8页
Heavy oil will play an important role in future resources exploitation.Factors such as reservoir heterogeneity and adverse oil/steam mobility ratio have led to severe steam channeling and fingering,thereby reduced con... Heavy oil will play an important role in future resources exploitation.Factors such as reservoir heterogeneity and adverse oil/steam mobility ratio have led to severe steam channeling and fingering,thereby reduced conformance efficiency and affected de-velopment response.Therefore,the research on profile control and water shut-off agents becomes increasingly important for thermal recovery wells.The requirements on the performances of profile control and water shut-off agents are discussed in conjunction with the physical properties of heavy oil reservoirs and the technical conditions of steam injection in China.Based on the mechanism of action,research progress and application status,5 agents are summarized including polymer gel,solid particles plugging agent,foam,water-in-oil emulsion and salt precipitation.Problems in each agent are mentioned,and optimization solutions are put for-ward.At last,the development trend of future profile control and water shut-off agents is put forward,i.e.synthesizing agents of low cost and high-temperature resistance,intensifying mechanism research,developing composite system,and researching on new technologies that are less harmful and environmental friendly. 展开更多
关键词 heavy oil thermal recovery profile control and water shut-off agents research progress development trend overview
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