Sintering and coking are critical barriers to achieving high performance in dry reforming of methane(DRM)catalysts.A finely dispersed and thermostable Ni-based catalyst is the key to address these issues.By leveraging...Sintering and coking are critical barriers to achieving high performance in dry reforming of methane(DRM)catalysts.A finely dispersed and thermostable Ni-based catalyst is the key to address these issues.By leveraging the intrinsic superiorities of high-entropy oxides in high-temperature stability and low atomic diffusivity,in this study,a highly dispersed Ni-based catalyst is synthesized via an entropycontrolled exsolution of active components.By increasing the number of transition-metal elements in spinel oxides,the active metalsupport interaction(MSI)can be continuously strengthened,which controls the exsolution and thermal stability of Ni-based active metal in harsh reaction conditions of DRM.An optimized medium-entropy spinel(Mg0.4Ni0.2Co0.2Zn0.2)Al2O4with the exsolution of finely dispersed Ni–Co nanoparticles displayed superior activity and stability in thermal DRM at 800°C and photothermal DRM.This entropy-controlled MSI and exsolution principle provides a significant strategy for designing robust catalysts resistant to sintering and coking for high-temperature reactions like DRM in thermal and photothermal systems.展开更多
The chemical looping steam reforming of methane(CL-SRM)holds immense potential for energy-efficient conversion of CH4into syngas and high-purity hydrogen.However,its large-scale implementation remains limited by hi...The chemical looping steam reforming of methane(CL-SRM)holds immense potential for energy-efficient conversion of CH4into syngas and high-purity hydrogen.However,its large-scale implementation remains limited by high operating temperatures and substantial energy requirements.This paper describes a non-thermal plasma-mediated CL-SRM process based on CH4/H2O redox cycles over lanthanum-based perovskites under mild conditions.The developed process achieves efficient CH4activation at 600℃,attaining 53.5%CH4conversion and0.57 mmol·g-1 H2with 92%purity over La0.5Ce0.5FeO3,while negligible conversion is observed under plasma-free conditions at the same furnace temperature.These performances surpass those observed under purely thermal conditions at 800℃.Mechanistic insights reveal that plasma plays a crucial role in generating vibrationally excited CH4v species,thereby markedly lowering the reaction barrier for CH4activation.The plasma-mediated CL-SRM process delivers energy through voltage-induced electron transfer,offering the potential for adiabatic reactor designs that minimize energy consumption compared with conventional combustion-based systems suffering from heat transfer limitations.展开更多
The urgent transition to low-carbon energy requires the utilization of CO2-rich natural gas.Dry reforming of methane(DRM)offers a viable carbon-for-carbon pathway for converting CH4 and CO2 into syngas,aligni...The urgent transition to low-carbon energy requires the utilization of CO2-rich natural gas.Dry reforming of methane(DRM)offers a viable carbon-for-carbon pathway for converting CH4 and CO2 into syngas,aligning with carbon neutrality goals.However,rapid catalyst deactivation due to coke formation and sintering remains the primary barrier to practical operation.To provide a systematic view of stabilization strategies,we summarize ten representative strategies and consolidate them into seven nanoscale design categories:encapsulation,alloying,promoter modification,defect and interface engineering,exsolution,single-atomization,and nano-island confinement.Future research directions warranting attention include the development of high-spatiotemporal-resolution in situ and operando techniques for monitoring catalyst structural evolution.Equally significant is the systematic development of multi-strategy synergy in catalyst design,with the incorporation of reaction modulation expected to further refine and extend this paradigm.In addition,bridging laboratory-level insights with industrial stability requirements remains important,particularly with respect to synthesis scalability,regeneration behavior,and practical feasibility in catalyst preparation and implementation.This comprehensive review summarizes deactivation mechanisms and stabilization strategies into a roadmap toward robust DRM catalysis.展开更多
Chemical Looping Reforming is an innovative methane-to-syngas conversion process offering high thermal efficiency,flexibility and H2/CO ratio of 2.This study investigates novel NiO-CeO2oxygen carrier combination...Chemical Looping Reforming is an innovative methane-to-syngas conversion process offering high thermal efficiency,flexibility and H2/CO ratio of 2.This study investigates novel NiO-CeO2oxygen carrier combination to leverage their individual benefits while exploring possible synergistic effects.Thermodynamic simulations using Aspen Plus show that NiO-CeO2mixtures promote partial oxidation,suppress carbon formation,and prevent total oxidation,improving cold gas efficiency(CGE),syngas purity,and exergy efficiency.This contrasts with single oxides:excessive NiO induces complete oxidation and CeO2alone suffers from carbon deposition.The optimal composition of 3 kmol·h-1NiO and 1 kmol·h-1CeO2provides enhanced syngas production,limited carbon deposition,92%CGE,and 91%exergy efficiency,causing better temperature control and limited airflow requirements in the oxidation reactor.This supports experimental setups that typically use high MeO/CH4 ratios.The mixture tolerates CO2in methane feed in proportions suitable for natural gas and biogas,promoting CO2utilization and reducing emissions.展开更多
Methanol steam reforming(MSR)represents a promising route for hydrogen production,leveraging the high energy density and liquid-phase storage advantages of methanol.Copper-based catalysts have become indispensable for...Methanol steam reforming(MSR)represents a promising route for hydrogen production,leveraging the high energy density and liquid-phase storage advantages of methanol.Copper-based catalysts have become indispensable for MSR due to their cost-effectiveness,exceptional catalytic activity,and tunable selectivity.However,persistent challenges such as thermal sintering,undesirable CO byproduct formation,diminished low-temperature reactivity,and long-term catalyst deactivation limit their broad industrial deployment.This review comprehensively examines the mechanistic pathways of MSR over Cu-based catalysts,with particular focus on differentiating catalyst formulations optimized for high-temperature(>200°C)versus low-temperature(<200°C)operation.It highlights the decisive influence of Cu nanoparticle size,electronic structure,and crystal structure on catalytic performance.Cutting-edge design strategies,including multi-element engineering,innovative synthesis techniques,and deactivation mitigation,are critically evaluated to elucidate mechanistic connections between atomic-scale structure and catalytic performance enhancement.Finally,industrial applications of commercial Cu/ZnO/Al2O3variants and their scalability challenges are discussed,alongside prospective strategies for catalyst innovation and engineering to advance next-generation hydrogen production.展开更多
The extensive emission of greenhouse gases,primarily CO2 and CH4,has contributed to intensified global warming.Dry reforming of methane(DRM,CH4+CO2→2CO+2H2)offers a pathway for the synergistic utilizat...The extensive emission of greenhouse gases,primarily CO2 and CH4,has contributed to intensified global warming.Dry reforming of methane(DRM,CH4+CO2→2CO+2H2)offers a pathway for the synergistic utilization of these two major greenhouse gases,presenting important implications for both environmental protection and energy sustainability.However,the catalysts still face the challenges such as carbon deposition and sintering of active metals,which adversely affect the catalytic performance and long-term stability.Oxygen vacancies,which are common lattice defects in metal oxides,have been demonstrated to improve the DRM performance by modulating the surface and interfacial properties of the catalysts.This review systematically summarizes research progresses in DRM over the past decade,outlines the major challenges and emphasizes the critical roles of oxygen vacancies in suppressing carbon deposition and inhibiting metal sintering.Furthermore,the mechanisms through which oxygen vacancies influence DRM reactions are discussed,combined with their formation pathways and regulation strategies.These insights provide essential theoretical foundations for the design and synthesis of highly efficient and stable DRM catalysts.展开更多
Multicomponent synergistic catalysis offers a promising strategy to address the severe coking in dry reforming of methane(DRM).In this study,a multicomponent Ni0.05Mn0.05Co0.05Zn0.05Mg0.8O catalyst was ...Multicomponent synergistic catalysis offers a promising strategy to address the severe coking in dry reforming of methane(DRM).In this study,a multicomponent Ni0.05Mn0.05Co0.05Zn0.05Mg0.8O catalyst was developed,with Zn stabilized MnO(Mn-Zn-O active phase)promotes the DRM performance of exsolved NiCo nanometals from MgO-based oxide.Zn doping improves MnO dispersion and enrichment on MgO support during reduction by forming Mn-Zn-O active phase,in which Mn serves as a redox-active promoter to enhance activation and dissociation of CH4and CO2.The reduction of Mn to a lower valence state can facilitate CO2adsorption and dissociation on the surface of catalysts,which also enhanced oxygen mobility to promote CH4activation and coke removal.The optimized Ni0.05Mn0.05Co0.05Zn0.05Mg0.8O catalyst demonstrates exceptional stability in thermal DRM at 800℃for 100 h.And in photothermal DRM,the catalyst also achieves outstanding activity under high gas flow rates with well-designed three-dimensional porosity catalytic reactor.展开更多
Methanol steam reforming(MSR)stands as a pivotal process for efficient hydrogen production.In this study,density functional theory(DFT)calculations were employed to conduct a comparative analysis of the MSR reaction m...Methanol steam reforming(MSR)stands as a pivotal process for efficient hydrogen production.In this study,density functional theory(DFT)calculations were employed to conduct a comparative analysis of the MSR reaction mechanism on PdCu(111)and PtCu(111)bimetallic surfaces.The investigation unveiled the underlying mechanism by which alloying modulates reaction pathways and overall catalytic performance.Notably,Cu sites were found to stabilize adsorption of OH and CH2O species,whereas Pd/Pt sites exhibited a preferential affinity for CO molecule.This spatial site separation facilitates progression along the formate pathway.PdCu(111)demonstrated superior overall catalytic performance compared to PtCu(111),with water dissociation identified as the rate-determining step(RDS),featuring an activation energy of only 0.74 eV.The bimetallic synergy breaks the inherent contradiction between the activity and selectivity of monometallic catalysts:Cu sites serve as a source of hydroxyl groups,while Pd/Pt sites enhance C–H bond cleavage efficiency,ultimately enabling high methanol conversion alongside low CO formation.From the perspectives of electronic structure and geometric configuration,this study establishes a theoretical framework to guide the rational design of high-performance bimetallic catalysts for MSR.展开更多
The CO2 dry reforming of methane(DRM)reaction represents a pivotal technology for CO2 utilization technology within the dual-carbon framework,offering significant advantages in carbon reduction,emission mitigati...The CO2 dry reforming of methane(DRM)reaction represents a pivotal technology for CO2 utilization technology within the dual-carbon framework,offering significant advantages in carbon reduction,emission mitigation,and the production of value-added chemicals.However,research reports on shaped catalysts suitable for industrial-scale DRM processes remain limited.In this work,a monolithic catalyst was constructed using honeycomb cordierite as the structural support,and the effects of organic and inorganic binders on the coating structure and catalytic performance were systematically investigated.Comparative studies revealed that the active coating fabricated with an inorganic aluminum sol exhibited a continuous uniform morphology and demonstrated excellent adhesion strength.Simultaneously during high-temperature calcination,elemental diffusion within the Al2O3 networks bridged the cordierite surface with active catalyst particles,forming a(Ni-Mg)AlxO4 composite structure.This created robust“metal-support”interactions between active sites and the residual alumina matrix.The interconnected mesoporous framework provided superior pore confinement,which ultimately contributed to strong coating adhesion,enhanced activity and improved resistance to carbon deposition in the monolithic m-NCM-Al-sol catalyst.In contrast,mesoporous network coatings derived from inorganic silica sol suffered from coating detachment and catalytic activity loss due to heterogeneous surface structures and poor adhesion.Organic binders demonstrated inferior performance compared to inorganic binders in macroscopic coating uniformity,adhesion strength,mesoporous confinement capability and localized electronic effects,resulting in the poorest catalytic performance among modified samples.Furthermore,by optimizing the aluminum sol coating process parameters such as binder content,active component dosage,and coating cycles,a synergistic balance between coating thickness and mass transfer performance was achieved.The optimized integrated catalyst demonstrated excellent performance in DRM reactions.This work provides valuable insights for controlling and constructing high-performance shaped catalysts with cordierite coatings.展开更多
Under the backdrop of“Carbon Peak and Carbon Neutrality”(dual carbon)goal in China,the methane-carbon dioxide reforming reaction has attracted considerable attention due to its environmental benefits of converting t...Under the backdrop of“Carbon Peak and Carbon Neutrality”(dual carbon)goal in China,the methane-carbon dioxide reforming reaction has attracted considerable attention due to its environmental benefits of converting two greenhouse gases(methane and carbon dioxide)into syngas and its promising industrial applications.Nickel(Ni)-based catalysts,with high catalytic activity,low cost,and abundant resources,are considered ideal candidates for industrial applications.In this article,three reaction kinetic models were briefly introduced,namely the Power-Law(PL)model,the Eley-Rideal(ER)model,and the Langmuir-Hinshelwood-Hougen-Watson(LHHW)model.Based on the LHHW model,the reaction kinetics and mechanisms of different catalytic systems were systematically discussed,including the properties of supports,the doping of noble metals and transition metals,the role of promoters,and the influence of the geometric and electronic structures of Ni on the reaction mechanism.Furthermore,the kinetics of carbon deposition and elimination on various catalysts were analyzed.Based on the reaction rate expressions for carbon elimination,the reasons for the high activity of transition metal iron(Fe)-doped catalysts and core-shell structured catalysts in carbon elimination were explained.Based on the detailed collation and comparative analysis of the reaction mechanisms and kinetic characteristics across diverse Ni-based catalytic systems,a theoretical guidance for the designing of high-performance catalysts was provided in this work.展开更多
To investigate influence of mixing modes on integrated process of co-pyrolysis of coal and biomass with CO2 reforming of methane(CP-CRM),Naomaohu coal(NMH)and elm(ELM)were chosen and three mixing modes(NMH/ELM,ELM/...To investigate influence of mixing modes on integrated process of co-pyrolysis of coal and biomass with CO2 reforming of methane(CP-CRM),Naomaohu coal(NMH)and elm(ELM)were chosen and three mixing modes(NMH/ELM,ELM/NMH and Blends)were examined over Ni-based reforming catalysts prepared by ball milling,and compared with co-pyrolysis under N2 atmosphere(CP-N2).The results show that the products distribution was significantly affected by the mixing mode.Tar yield during CP-CRM under Blends model was higher than those of NMH/ELM and ELM/NMH,increasing by 35.29%compared with CP-N2.Meanwhile,light oil content in the tar was higher than those of NMH/ELM and ELM/NMH,but the pitch content was opposite.Phenols content in tar from Blends model was 19.52%higher than that of CP-N2,along with more free radicals in tar than that of CP-N2,which was mainly ascribed to the enhanced heat and mass transfer between raw material particles by mechanical mixing,making the co-pyrolysis process more complete.At the same time,the mechanical mixing was conducive to more efficient action of hydrogen-rich free radicals(such as·H,·CHx)on pyrolysis products,suppressing the secondary cracking and polymerization.The results provide a good guidance for regulating tar yield and compositions of the co-pyrolysis process.展开更多
Tetragonal ZrO2(t-ZrO2)with abundant oxygen vacancies offers a viable approach to support Ni catalysts for enhanced catalytic performance in dry reforming of methane(DRM).However,the application of t-ZrO2is l...Tetragonal ZrO2(t-ZrO2)with abundant oxygen vacancies offers a viable approach to support Ni catalysts for enhanced catalytic performance in dry reforming of methane(DRM).However,the application of t-ZrO2is limited by its inherent thermal instability.Herein,we evaluated Ni3Fe1alloy supported on m-ZrO2and t-ZrO2stabilized with CaO or Y2O3for DRM.Ni3Fe1/m-ZrO2showed inferior activity,while Ni3Fe1/Y2O3—t-ZrO2retained t-ZrO2structure but exhibited poor stability.In contrast,Ni3Fe1/CaO—tZrO2demonstrated high stability,maintaining CH4 and CO2conversions of 78.0%and 87.2%with H2/CO ratio of 0.95 at 800℃.This is attributed to the CaO dopant,which not only stabilized t-ZrO2phase but also strengthened metal—support interaction at the Ni3Fe1—ZrO2interface,increased oxygen vacancy concentration,and improved surface basicity.Notably,these significantly facilitated CH4 dissociation and CO2activation,establishing an effective balance between carbon formation and gasification,thereby improving the coke resistance of the catalyst.展开更多
A new strategy for preparing highly dispersed,richer oxygen vacancies Ni/ZrO2catalysts derived from UiO-66-NH2is reported via pyrolysis-calcination removal of the ligands under N2,CO2,and Air atmospheres f...A new strategy for preparing highly dispersed,richer oxygen vacancies Ni/ZrO2catalysts derived from UiO-66-NH2is reported via pyrolysis-calcination removal of the ligands under N2,CO2,and Air atmospheres followed by loading Ni with 5 wt.%via wet impregnation method.Subsequently,the low-temperature dry reforming of methane(DRM)reaction over the obtained Ni/ZrO2catalysts was preliminarily investigated.The results indicated that the Ni/ZrO2C catalyst,obtained by two-step pyrolysis in CO2,contained smaller Ni particles with a size of only 5-7 nm and possessed a hierarchical porous structure,as well as richer oxygen vacancies and basic active sites compared to the other two catalysts.Its catalytic activity in the DRM reaction presented the highest initial conversion of CH4(35%)and CO2(26%)at 600℃,which was 5%higher than that of the Ni/ZrO2-N and Ni/ZrO2-O catalysts obtained by two-step pyrolysis under an N2atmosphere and one-step pyrolysis under an air atmosphere,respectively.Meanwhile,an in-situ DRIFTS experiment revealed that Ni/ZrO2-C could enhance the adsorption and activation of CO2by promoting the formation of formate as an intermediate of CO hydrogenation and reverse water-gas shift(RWGS)reactions,which in turn facilitates the decomposition of CH4.展开更多
Aiming at the problem of innovative talent training in the industry field in characteristic software colleges,combined with the actual situation of Software College of Northeastern University,this paper analyzes the c...Aiming at the problem of innovative talent training in the industry field in characteristic software colleges,combined with the actual situation of Software College of Northeastern University,this paper analyzes the construction requirements of characteristic talent training mode and training scheme,puts forward the reform of characteristic software innovative talent training scheme integrating production and education,and takes the characteristic direction of financial technology as an example to introduce the curriculum construction based on industry-education integration and school-enterprise cooperation.展开更多
The rapid development of artificial intelligence(AI)has placed significant pressure on universities to rethink how they train software engineering students.Tools like GitHub Copilot can now generate basic code in seco...The rapid development of artificial intelligence(AI)has placed significant pressure on universities to rethink how they train software engineering students.Tools like GitHub Copilot can now generate basic code in seconds.This raises important questions:What is the value of traditional programming education?What role should instructors play when AI becomes a powerful teaching assistant?How should the goals of software engineering programs change as companies increasingly use AI to handle coding tasks?This paper explores the key challenges AI brings to software engineering education and proposes practical strategies for updating talent development models to meet these changes.展开更多
Chemical looping reforming of coke oven gas(COG)is a promising technology for producing low-cost hydrogen,but the presence of coal tar with relatively high concentration presents a significant challenge for the design...Chemical looping reforming of coke oven gas(COG)is a promising technology for producing low-cost hydrogen,but the presence of coal tar with relatively high concentration presents a significant challenge for the design of oxygen carriers.In the present work,the effect of naphthalene(a coal tar model compound)on the activity and structure stability of LaFeO3-based perovskite oxygen carriers for chemical looping reforming of COG was investigated.We found that the presence of naphthalene would inhibit the methane conversion and lead to serious carbon deposits on oxygen carriers,thus reducing the structure stability during the redox cycling.In response to the aforementioned findings,a series of La1-xYxFe0.93Ni0.07O3-λperovskite oxygen carriers were designed based on co-doping of A and B sites strategy.The presence of Ni2+at B-site can improve the capacity of oxygen carrier for methane activation,and the Y3+substitution at A-site may enhance the activity of lattice oxygen via regulating the Fe-O bond-length.With a suitable content of Ni and Y,the La0.9Y0.1Fe0.93Ni0.07O3-λoxygen carrier shows superior performance for chemical looping reforming of COG,with the CH4conversion higher than 99%and excellent stability during long-term redox cycles in the presence of 400 ppm naphthalene at 800℃.This work may provide a viable strategy for developing robust perovskite oxygen carriers for the chemical looping reforming of fuels with relatively high content of impurities.展开更多
China’s rapid economic growth has long relied on a model of large-scale urban land acquisition and transfer,which is now increasingly constrained by central government policies.In response,local governments have impl...China’s rapid economic growth has long relied on a model of large-scale urban land acquisition and transfer,which is now increasingly constrained by central government policies.In response,local governments have implemented the“Area-Based Evaluation Mechanism”Reform to reallocate land resources to more efficient enterprises;however,the specific effects of this reform remain unclear.This study investigates the economic impact of China’s“Area-Based Evaluation Mechanism”Reform using panel data on 2530 county-level units from 2011 to 2020 and a multiperiod difference-in-differences model.The results show that the reform increased county-level economic growth by approximately 1.4 percentage points in the baseline case.Two mechanisms are identified:(1)a positive incentive channel,which reduces resource misallocation between efficient and inefficient enterprises by 0.254 units;and(2)a reverse pressure channel,which drives enterprises to increase R&D investment by 0.207,boosts innovation output by 0.119,and thereby enhances total factor productivity by 0.283.Heterogeneity analyses reveal that the reform’s effects are more pronounced in eastern and Yangtze River Delta regions,counties with higher land output values,and those with a lower proportion of industrial activity.In contrast,the impact is limited in inland regions,areas with lower land output values,and regions with higher industrial proportions.These results remain robust after a series of tests and suggest that promoting economic growth through land reform requires advancing market-oriented approaches to fully utilize the market mechanism.The study offers practical implications for designing more effective and incentive-compatible governance frameworks.展开更多
To meet the need for cultivating application-oriented talents in local universities,this study introduced a project-based learning approach into the reform of bioinformatics experimental teaching.The course was struct...To meet the need for cultivating application-oriented talents in local universities,this study introduced a project-based learning approach into the reform of bioinformatics experimental teaching.The course was structured around a project titled"Influenza Virus Analysis",comprising four progressive modules:database utilization and information retrieval,sequence alignment and phylogenetic analysis,functional and structural prediction,and omics data analysis.These modules were integrated into a coherent research workflow that connected fragmented knowledge and technical skills.During implementation,flipped classroom and group collaboration methods were employed,alongside the establishment of a diversified assessment system emphasizing process evaluation.Teaching practice indicates that the reform effectively enhances students professional application skills,learning experience,and scientific literacy,facilitating a shift from"tool operation"to"problem-solving"capabilities.This study provides a reference model for the reform of bioinformatics experimental teaching in local universities.展开更多
The deep integration of digitalization and intelligence presents unprecedented challenges to traditional teaching models.To address common issues such as fragmented knowledge systems,weak practical links,insufficient ...The deep integration of digitalization and intelligence presents unprecedented challenges to traditional teaching models.To address common issues such as fragmented knowledge systems,weak practical links,insufficient personalized cultivation,and single evaluation mode,this study constructs a systematic reform framework of“concept-technology empowerment-mechanism innovation”based on the concept of digital-intelligence integration and vocational-undergraduate collaborative education.It proposes a four-dimensional implementation path:“driven by dynamic knowledge graphs,by project-flow simulation,supported by AI-human collaborative teaching,and guaranteed by an integrated practical teaching system.”The research specifically focuses on the construction of a higher vocational-undergraduate integrated practical teaching system,forming a progressive practical teaching closed loop of“basic skill training-comprehensive ability cultivation-innovative ability stimulation”through the construction of a cross-stage,cross-disciplinary,virtual-real combined practical platform.The results show that this system can effectively promote the transformation of theoretical knowledge into practical ability and enhance students’comprehensive literacy and innovative spirit,providing a replicable systematic solution for higher education teaching reform under higher vocational-undergraduate cooperation.展开更多
Purpose:This research sets out to explore the practical application value of an innovative teaching mode that organically combines evidence-based medicine(EBM)with artificial intelligence(AI),and analyze its applicati...Purpose:This research sets out to explore the practical application value of an innovative teaching mode that organically combines evidence-based medicine(EBM)with artificial intelligence(AI),and analyze its application effect on undergraduate medical students during their ophthalmology internship.Methods:This research team independently built a multi-functional online teaching platform integrating EBM and AI technologies,which incorporates specialized evidence resource libraries,AI auxiliary diagnosis tools,and simulated clinical case modules.A total of 30 fifth-year clinical undergraduates receiving ophthalmology internship training were enrolled as research subjects and randomly assigned into two groups with 15 participants each.The experimental group adopted the newly developed EBM-AI integrated teaching method,while the control group received the conventional offline teaching mode.Multiple indicators were adopted to evaluate the teaching effect,covering students’professional theoretical reserves,EBM and AI-related comprehensive abilities,clinical decision-making level,autonomous learning enthusiasm,and subjective evaluation of teaching quality.Results:Before the intervention,there was no statistical difference in the basic ophthalmology knowledge reserve between the two groups(P>0.05).After the implementation of different teaching schemes,the experimental group outperformed the control group in all evaluation indicators.To be specific,the experimental group obtained higher scores in overall theoretical assessment(86.12±4.05 vs.74.93±5.62,P<0.001)and EBM/AI specialized knowledge test(36.25±2.31 vs.26.80±3.17,P<0.001).Meanwhile,the group also achieved better results in the Script Concordance Test(SCT)for clinical decision-making ability(81.60±5.24 vs.63.87±6.08,P<0.001).In terms of learning initiative,the weekly self-study duration of students in the experimental group was obviously longer than that of the control group(4.02±0.71 vs.1.68±0.44,P<0.001).Additionally,the student satisfaction rate of the new teaching model reached 93.3%,which was notably higher than 73.3%of the traditional teaching group(P=0.031).Conclusion:The integrated teaching model combining EBM and AI can effectively help interns consolidate EBM and AI professional knowledge,optimize clinical case analysis and decision-making capabilities,and stimulate their enthusiasm for independent learning.Importantly,the new teaching method will not affect students’mastery of basic ophthalmology knowledge.This optimized teaching scheme can serve as a reliable reference for promoting the innovative reform of modern ophthalmology higher education.展开更多
基金supported by the National Key R&D Program of China(2023YFB4104600)National Natural Science Foundation of China(52572313)+1 种基金Tangshan Talent Funding Project(A202202007)Shenzhen Science and Technology Innovation Commission under Grant No.20231120185819001。
摘要Sintering and coking are critical barriers to achieving high performance in dry reforming of methane(DRM)catalysts.A finely dispersed and thermostable Ni-based catalyst is the key to address these issues.By leveraging the intrinsic superiorities of high-entropy oxides in high-temperature stability and low atomic diffusivity,in this study,a highly dispersed Ni-based catalyst is synthesized via an entropycontrolled exsolution of active components.By increasing the number of transition-metal elements in spinel oxides,the active metalsupport interaction(MSI)can be continuously strengthened,which controls the exsolution and thermal stability of Ni-based active metal in harsh reaction conditions of DRM.An optimized medium-entropy spinel(Mg0.4Ni0.2Co0.2Zn0.2)Al2O4with the exsolution of finely dispersed Ni–Co nanoparticles displayed superior activity and stability in thermal DRM at 800°C and photothermal DRM.This entropy-controlled MSI and exsolution principle provides a significant strategy for designing robust catalysts resistant to sintering and coking for high-temperature reactions like DRM in thermal and photothermal systems.
基金supported by the National Key Research and Development Program(2023YFA1507800 and 2021YFA1501303)the National Natural Science Foundation of China(22208239,22121004,and U20B6002)+3 种基金the China Postdoctoral Science Foundation(2021TQ0240)the Haihe Laboratory of Sustainable Chemical Transformations(CYZC202107)the Program of Introducing Talents of Discipline to Universities(BP0618007)the XPLORER PRIZE。
摘要The chemical looping steam reforming of methane(CL-SRM)holds immense potential for energy-efficient conversion of CH4into syngas and high-purity hydrogen.However,its large-scale implementation remains limited by high operating temperatures and substantial energy requirements.This paper describes a non-thermal plasma-mediated CL-SRM process based on CH4/H2O redox cycles over lanthanum-based perovskites under mild conditions.The developed process achieves efficient CH4activation at 600℃,attaining 53.5%CH4conversion and0.57 mmol·g-1 H2with 92%purity over La0.5Ce0.5FeO3,while negligible conversion is observed under plasma-free conditions at the same furnace temperature.These performances surpass those observed under purely thermal conditions at 800℃.Mechanistic insights reveal that plasma plays a crucial role in generating vibrationally excited CH4v species,thereby markedly lowering the reaction barrier for CH4activation.The plasma-mediated CL-SRM process delivers energy through voltage-induced electron transfer,offering the potential for adiabatic reactor designs that minimize energy consumption compared with conventional combustion-based systems suffering from heat transfer limitations.
基金supported by National Key Research and Development Program of China(2021YFA1500500)Chinese Academy of Sciences(CAS)Project for Young Scientists in Basic Research(YSBR-051)+11 种基金National Natural Science Foundation of China(22525021,22302185,22221003,22250007,and 22361162655)the Science and Technology Development Fund(FDCT)of Macao S.A.R(0070/2023/AFJ)Fundamental Research Funds for the Central Universities(WK9990000167)Special Science and Technology Innovation Program for Carbon Peak and Carbon Neutralization of Jiangsu Province(BE2025014)the State Key Laboratory of Catalysis(2024SKL-A-011)University of Science and Technology of China-Xinjiang Normal University Counterpart Cooperation and Development Joint Fundthe Key Project of Natural Science Foundation of Anhui Province(2508085ZD020)International Partnership Program of Chinese Academy of Sciences(123GJHZ2022101GC)the Young Elite Scientists Sponsorship Program by the China Association for Science and Technology(2022QNRC001)the Anhui Natural Science Foundation for Young Scholars(2308085QB53)support from the New Cornerstone Science Foundation through the XPLORER PRIZEsupport from the USTC Tang Scholar。
摘要The urgent transition to low-carbon energy requires the utilization of CO2-rich natural gas.Dry reforming of methane(DRM)offers a viable carbon-for-carbon pathway for converting CH4 and CO2 into syngas,aligning with carbon neutrality goals.However,rapid catalyst deactivation due to coke formation and sintering remains the primary barrier to practical operation.To provide a systematic view of stabilization strategies,we summarize ten representative strategies and consolidate them into seven nanoscale design categories:encapsulation,alloying,promoter modification,defect and interface engineering,exsolution,single-atomization,and nano-island confinement.Future research directions warranting attention include the development of high-spatiotemporal-resolution in situ and operando techniques for monitoring catalyst structural evolution.Equally significant is the systematic development of multi-strategy synergy in catalyst design,with the incorporation of reaction modulation expected to further refine and extend this paradigm.In addition,bridging laboratory-level insights with industrial stability requirements remains important,particularly with respect to synthesis scalability,regeneration behavior,and practical feasibility in catalyst preparation and implementation.This comprehensive review summarizes deactivation mechanisms and stabilization strategies into a roadmap toward robust DRM catalysis.
基金supported by the Lebanese American University President's Intramural Research Fund PIRF I0046。
摘要Chemical Looping Reforming is an innovative methane-to-syngas conversion process offering high thermal efficiency,flexibility and H2/CO ratio of 2.This study investigates novel NiO-CeO2oxygen carrier combination to leverage their individual benefits while exploring possible synergistic effects.Thermodynamic simulations using Aspen Plus show that NiO-CeO2mixtures promote partial oxidation,suppress carbon formation,and prevent total oxidation,improving cold gas efficiency(CGE),syngas purity,and exergy efficiency.This contrasts with single oxides:excessive NiO induces complete oxidation and CeO2alone suffers from carbon deposition.The optimal composition of 3 kmol·h-1NiO and 1 kmol·h-1CeO2provides enhanced syngas production,limited carbon deposition,92%CGE,and 91%exergy efficiency,causing better temperature control and limited airflow requirements in the oxidation reactor.This supports experimental setups that typically use high MeO/CH4 ratios.The mixture tolerates CO2in methane feed in proportions suitable for natural gas and biogas,promoting CO2utilization and reducing emissions.
基金supported by the National Natural Science Foundation of China(No.22208374)the Excellent Youth Scientist Award Foundation of Shandong Province(No.ZR2024YQ009)+2 种基金the Distinguished Young Scholars of the National Natural Science Foundation of China(No.22322814)CNPC Innovation Found(2022DQ02-0607)the Fundamental Research Funds for the Central Universities(No.24CX07006A).
摘要Methanol steam reforming(MSR)represents a promising route for hydrogen production,leveraging the high energy density and liquid-phase storage advantages of methanol.Copper-based catalysts have become indispensable for MSR due to their cost-effectiveness,exceptional catalytic activity,and tunable selectivity.However,persistent challenges such as thermal sintering,undesirable CO byproduct formation,diminished low-temperature reactivity,and long-term catalyst deactivation limit their broad industrial deployment.This review comprehensively examines the mechanistic pathways of MSR over Cu-based catalysts,with particular focus on differentiating catalyst formulations optimized for high-temperature(>200°C)versus low-temperature(<200°C)operation.It highlights the decisive influence of Cu nanoparticle size,electronic structure,and crystal structure on catalytic performance.Cutting-edge design strategies,including multi-element engineering,innovative synthesis techniques,and deactivation mitigation,are critically evaluated to elucidate mechanistic connections between atomic-scale structure and catalytic performance enhancement.Finally,industrial applications of commercial Cu/ZnO/Al2O3variants and their scalability challenges are discussed,alongside prospective strategies for catalyst innovation and engineering to advance next-generation hydrogen production.
基金Supported by the National Natural Science Foundation of China(22476199,U23A20125)Zhejiang Provincial Natural Science Foundation of China(LY23B070002,LQN25B030007)+1 种基金Ningbo Municipal Natural Science Foundation of China(2023J046)China Postdoctoral Science Foundation(2024M753338).
摘要The extensive emission of greenhouse gases,primarily CO2 and CH4,has contributed to intensified global warming.Dry reforming of methane(DRM,CH4+CO2→2CO+2H2)offers a pathway for the synergistic utilization of these two major greenhouse gases,presenting important implications for both environmental protection and energy sustainability.However,the catalysts still face the challenges such as carbon deposition and sintering of active metals,which adversely affect the catalytic performance and long-term stability.Oxygen vacancies,which are common lattice defects in metal oxides,have been demonstrated to improve the DRM performance by modulating the surface and interfacial properties of the catalysts.This review systematically summarizes research progresses in DRM over the past decade,outlines the major challenges and emphasizes the critical roles of oxygen vacancies in suppressing carbon deposition and inhibiting metal sintering.Furthermore,the mechanisms through which oxygen vacancies influence DRM reactions are discussed,combined with their formation pathways and regulation strategies.These insights provide essential theoretical foundations for the design and synthesis of highly efficient and stable DRM catalysts.
基金supported by the National Key R&D Program of China(2023YFB4104600)the National Natural Science Foundation of China(52572313)+1 种基金the Tangshan Talent Funding Project(A202202007)the Shenzhen Science and Technology Innovation Commission(20231120185819001).
摘要Multicomponent synergistic catalysis offers a promising strategy to address the severe coking in dry reforming of methane(DRM).In this study,a multicomponent Ni0.05Mn0.05Co0.05Zn0.05Mg0.8O catalyst was developed,with Zn stabilized MnO(Mn-Zn-O active phase)promotes the DRM performance of exsolved NiCo nanometals from MgO-based oxide.Zn doping improves MnO dispersion and enrichment on MgO support during reduction by forming Mn-Zn-O active phase,in which Mn serves as a redox-active promoter to enhance activation and dissociation of CH4and CO2.The reduction of Mn to a lower valence state can facilitate CO2adsorption and dissociation on the surface of catalysts,which also enhanced oxygen mobility to promote CH4activation and coke removal.The optimized Ni0.05Mn0.05Co0.05Zn0.05Mg0.8O catalyst demonstrates exceptional stability in thermal DRM at 800℃for 100 h.And in photothermal DRM,the catalyst also achieves outstanding activity under high gas flow rates with well-designed three-dimensional porosity catalytic reactor.
基金Supported by Fundamental Research Program of Shanxi Province(202503021212289)the Research Start-up Funds of Shanxi College of Technology。
摘要Methanol steam reforming(MSR)stands as a pivotal process for efficient hydrogen production.In this study,density functional theory(DFT)calculations were employed to conduct a comparative analysis of the MSR reaction mechanism on PdCu(111)and PtCu(111)bimetallic surfaces.The investigation unveiled the underlying mechanism by which alloying modulates reaction pathways and overall catalytic performance.Notably,Cu sites were found to stabilize adsorption of OH and CH2O species,whereas Pd/Pt sites exhibited a preferential affinity for CO molecule.This spatial site separation facilitates progression along the formate pathway.PdCu(111)demonstrated superior overall catalytic performance compared to PtCu(111),with water dissociation identified as the rate-determining step(RDS),featuring an activation energy of only 0.74 eV.The bimetallic synergy breaks the inherent contradiction between the activity and selectivity of monometallic catalysts:Cu sites serve as a source of hydroxyl groups,while Pd/Pt sites enhance C–H bond cleavage efficiency,ultimately enabling high methanol conversion alongside low CO formation.From the perspectives of electronic structure and geometric configuration,this study establishes a theoretical framework to guide the rational design of high-performance bimetallic catalysts for MSR.
基金Supported by the National Natural Science Foundation of China(22578255,22178202)the Central Government Guidance Fund for Local Science and Technology Development(YDZJSX2024D004)the Key Research and Development Special Program of Shanxi Province(202402090301006,202302090301004)。
摘要The CO2 dry reforming of methane(DRM)reaction represents a pivotal technology for CO2 utilization technology within the dual-carbon framework,offering significant advantages in carbon reduction,emission mitigation,and the production of value-added chemicals.However,research reports on shaped catalysts suitable for industrial-scale DRM processes remain limited.In this work,a monolithic catalyst was constructed using honeycomb cordierite as the structural support,and the effects of organic and inorganic binders on the coating structure and catalytic performance were systematically investigated.Comparative studies revealed that the active coating fabricated with an inorganic aluminum sol exhibited a continuous uniform morphology and demonstrated excellent adhesion strength.Simultaneously during high-temperature calcination,elemental diffusion within the Al2O3 networks bridged the cordierite surface with active catalyst particles,forming a(Ni-Mg)AlxO4 composite structure.This created robust“metal-support”interactions between active sites and the residual alumina matrix.The interconnected mesoporous framework provided superior pore confinement,which ultimately contributed to strong coating adhesion,enhanced activity and improved resistance to carbon deposition in the monolithic m-NCM-Al-sol catalyst.In contrast,mesoporous network coatings derived from inorganic silica sol suffered from coating detachment and catalytic activity loss due to heterogeneous surface structures and poor adhesion.Organic binders demonstrated inferior performance compared to inorganic binders in macroscopic coating uniformity,adhesion strength,mesoporous confinement capability and localized electronic effects,resulting in the poorest catalytic performance among modified samples.Furthermore,by optimizing the aluminum sol coating process parameters such as binder content,active component dosage,and coating cycles,a synergistic balance between coating thickness and mass transfer performance was achieved.The optimized integrated catalyst demonstrated excellent performance in DRM reactions.This work provides valuable insights for controlling and constructing high-performance shaped catalysts with cordierite coatings.
基金Supported by Innovation Capability Support Program of Shaanxi(2024RS-CXTD-53,2024ZC-KJXX-096)the Key R&D Program of Shaanxi Province(2022QCY-LL-69)Xi’an Science and Technology Project(24GXFW0089)。
摘要Under the backdrop of“Carbon Peak and Carbon Neutrality”(dual carbon)goal in China,the methane-carbon dioxide reforming reaction has attracted considerable attention due to its environmental benefits of converting two greenhouse gases(methane and carbon dioxide)into syngas and its promising industrial applications.Nickel(Ni)-based catalysts,with high catalytic activity,low cost,and abundant resources,are considered ideal candidates for industrial applications.In this article,three reaction kinetic models were briefly introduced,namely the Power-Law(PL)model,the Eley-Rideal(ER)model,and the Langmuir-Hinshelwood-Hougen-Watson(LHHW)model.Based on the LHHW model,the reaction kinetics and mechanisms of different catalytic systems were systematically discussed,including the properties of supports,the doping of noble metals and transition metals,the role of promoters,and the influence of the geometric and electronic structures of Ni on the reaction mechanism.Furthermore,the kinetics of carbon deposition and elimination on various catalysts were analyzed.Based on the reaction rate expressions for carbon elimination,the reasons for the high activity of transition metal iron(Fe)-doped catalysts and core-shell structured catalysts in carbon elimination were explained.Based on the detailed collation and comparative analysis of the reaction mechanisms and kinetic characteristics across diverse Ni-based catalytic systems,a theoretical guidance for the designing of high-performance catalysts was provided in this work.
基金Supported by Science and Technology Planning Project of Xinjiang Uygur Autonomous Region(2023D04025)Tianshan Talent Training Program(2023TSYCJU0004)+1 种基金Natural Science Foundation of Xinjiang Uygur Autonomous Region(2024D01D02)National Key Research and Development Program Project(2023YFB4103802)。
摘要To investigate influence of mixing modes on integrated process of co-pyrolysis of coal and biomass with CO2 reforming of methane(CP-CRM),Naomaohu coal(NMH)and elm(ELM)were chosen and three mixing modes(NMH/ELM,ELM/NMH and Blends)were examined over Ni-based reforming catalysts prepared by ball milling,and compared with co-pyrolysis under N2 atmosphere(CP-N2).The results show that the products distribution was significantly affected by the mixing mode.Tar yield during CP-CRM under Blends model was higher than those of NMH/ELM and ELM/NMH,increasing by 35.29%compared with CP-N2.Meanwhile,light oil content in the tar was higher than those of NMH/ELM and ELM/NMH,but the pitch content was opposite.Phenols content in tar from Blends model was 19.52%higher than that of CP-N2,along with more free radicals in tar than that of CP-N2,which was mainly ascribed to the enhanced heat and mass transfer between raw material particles by mechanical mixing,making the co-pyrolysis process more complete.At the same time,the mechanical mixing was conducive to more efficient action of hydrogen-rich free radicals(such as·H,·CHx)on pyrolysis products,suppressing the secondary cracking and polymerization.The results provide a good guidance for regulating tar yield and compositions of the co-pyrolysis process.
基金the National Natural Science Foundation of China(22278286)Science Foundation for Distinguished Young Scholar of Shanxi Province(202303021223001)。
摘要Tetragonal ZrO2(t-ZrO2)with abundant oxygen vacancies offers a viable approach to support Ni catalysts for enhanced catalytic performance in dry reforming of methane(DRM).However,the application of t-ZrO2is limited by its inherent thermal instability.Herein,we evaluated Ni3Fe1alloy supported on m-ZrO2and t-ZrO2stabilized with CaO or Y2O3for DRM.Ni3Fe1/m-ZrO2showed inferior activity,while Ni3Fe1/Y2O3—t-ZrO2retained t-ZrO2structure but exhibited poor stability.In contrast,Ni3Fe1/CaO—tZrO2demonstrated high stability,maintaining CH4 and CO2conversions of 78.0%and 87.2%with H2/CO ratio of 0.95 at 800℃.This is attributed to the CaO dopant,which not only stabilized t-ZrO2phase but also strengthened metal—support interaction at the Ni3Fe1—ZrO2interface,increased oxygen vacancy concentration,and improved surface basicity.Notably,these significantly facilitated CH4 dissociation and CO2activation,establishing an effective balance between carbon formation and gasification,thereby improving the coke resistance of the catalyst.
基金supported by the National Natural Science Foundation of China(No.22308012)the National Key Laboratory of Efficient Exploitation and Clean Utilization of Coal Resources Open Fund Grant for General Project(No.2021-CMCU-KF005).
摘要A new strategy for preparing highly dispersed,richer oxygen vacancies Ni/ZrO2catalysts derived from UiO-66-NH2is reported via pyrolysis-calcination removal of the ligands under N2,CO2,and Air atmospheres followed by loading Ni with 5 wt.%via wet impregnation method.Subsequently,the low-temperature dry reforming of methane(DRM)reaction over the obtained Ni/ZrO2catalysts was preliminarily investigated.The results indicated that the Ni/ZrO2C catalyst,obtained by two-step pyrolysis in CO2,contained smaller Ni particles with a size of only 5-7 nm and possessed a hierarchical porous structure,as well as richer oxygen vacancies and basic active sites compared to the other two catalysts.Its catalytic activity in the DRM reaction presented the highest initial conversion of CH4(35%)and CO2(26%)at 600℃,which was 5%higher than that of the Ni/ZrO2-N and Ni/ZrO2-O catalysts obtained by two-step pyrolysis under an N2atmosphere and one-step pyrolysis under an air atmosphere,respectively.Meanwhile,an in-situ DRIFTS experiment revealed that Ni/ZrO2-C could enhance the adsorption and activation of CO2by promoting the formation of formate as an intermediate of CO hydrogenation and reverse water-gas shift(RWGS)reactions,which in turn facilitates the decomposition of CH4.
摘要Aiming at the problem of innovative talent training in the industry field in characteristic software colleges,combined with the actual situation of Software College of Northeastern University,this paper analyzes the construction requirements of characteristic talent training mode and training scheme,puts forward the reform of characteristic software innovative talent training scheme integrating production and education,and takes the characteristic direction of financial technology as an example to introduce the curriculum construction based on industry-education integration and school-enterprise cooperation.
基金supported in part by the Northeastern University’s 2024 Undergraduate Education and Teaching Reform Research Project:Innovation and Practice of Professional Course Teaching Paradigms in the Context of Digital Education.
摘要The rapid development of artificial intelligence(AI)has placed significant pressure on universities to rethink how they train software engineering students.Tools like GitHub Copilot can now generate basic code in seconds.This raises important questions:What is the value of traditional programming education?What role should instructors play when AI becomes a powerful teaching assistant?How should the goals of software engineering programs change as companies increasingly use AI to handle coding tasks?This paper explores the key challenges AI brings to software engineering education and proposes practical strategies for updating talent development models to meet these changes.
基金financially supported by the National Natural Science Foundation of China(Nos.52174279,U2202251 and 52266008)Major Science and Technology Projects in Yunnan Province(No:202302AG050005).
摘要Chemical looping reforming of coke oven gas(COG)is a promising technology for producing low-cost hydrogen,but the presence of coal tar with relatively high concentration presents a significant challenge for the design of oxygen carriers.In the present work,the effect of naphthalene(a coal tar model compound)on the activity and structure stability of LaFeO3-based perovskite oxygen carriers for chemical looping reforming of COG was investigated.We found that the presence of naphthalene would inhibit the methane conversion and lead to serious carbon deposits on oxygen carriers,thus reducing the structure stability during the redox cycling.In response to the aforementioned findings,a series of La1-xYxFe0.93Ni0.07O3-λperovskite oxygen carriers were designed based on co-doping of A and B sites strategy.The presence of Ni2+at B-site can improve the capacity of oxygen carrier for methane activation,and the Y3+substitution at A-site may enhance the activity of lattice oxygen via regulating the Fe-O bond-length.With a suitable content of Ni and Y,the La0.9Y0.1Fe0.93Ni0.07O3-λoxygen carrier shows superior performance for chemical looping reforming of COG,with the CH4conversion higher than 99%and excellent stability during long-term redox cycles in the presence of 400 ppm naphthalene at 800℃.This work may provide a viable strategy for developing robust perovskite oxygen carriers for the chemical looping reforming of fuels with relatively high content of impurities.
基金supported by the 2025 STCSM Soft Science Research Project[Grant No.25692115900].
摘要China’s rapid economic growth has long relied on a model of large-scale urban land acquisition and transfer,which is now increasingly constrained by central government policies.In response,local governments have implemented the“Area-Based Evaluation Mechanism”Reform to reallocate land resources to more efficient enterprises;however,the specific effects of this reform remain unclear.This study investigates the economic impact of China’s“Area-Based Evaluation Mechanism”Reform using panel data on 2530 county-level units from 2011 to 2020 and a multiperiod difference-in-differences model.The results show that the reform increased county-level economic growth by approximately 1.4 percentage points in the baseline case.Two mechanisms are identified:(1)a positive incentive channel,which reduces resource misallocation between efficient and inefficient enterprises by 0.254 units;and(2)a reverse pressure channel,which drives enterprises to increase R&D investment by 0.207,boosts innovation output by 0.119,and thereby enhances total factor productivity by 0.283.Heterogeneity analyses reveal that the reform’s effects are more pronounced in eastern and Yangtze River Delta regions,counties with higher land output values,and those with a lower proportion of industrial activity.In contrast,the impact is limited in inland regions,areas with lower land output values,and regions with higher industrial proportions.These results remain robust after a series of tests and suggest that promoting economic growth through land reform requires advancing market-oriented approaches to fully utilize the market mechanism.The study offers practical implications for designing more effective and incentive-compatible governance frameworks.
基金Supported by Undergraduate Higher Education Teaching Quality and Reform Projects of Guangdong Province(Yuejiao Gao Han[2024]No.9,Yuejiao Gao Han[2024]No.30)Guangdong Basic and Applied Basic Research Foundation(2023A1515110973)+1 种基金Guangdong Provincial Young Innovative Talents Project of General Colleges and Universities(2023KQNCX089)Quality Engineering and Teaching Reform Projects of Zhaoqing University(zlgc202239,zlgc202207,zlgc2024005,zlgc2024038).
摘要To meet the need for cultivating application-oriented talents in local universities,this study introduced a project-based learning approach into the reform of bioinformatics experimental teaching.The course was structured around a project titled"Influenza Virus Analysis",comprising four progressive modules:database utilization and information retrieval,sequence alignment and phylogenetic analysis,functional and structural prediction,and omics data analysis.These modules were integrated into a coherent research workflow that connected fragmented knowledge and technical skills.During implementation,flipped classroom and group collaboration methods were employed,alongside the establishment of a diversified assessment system emphasizing process evaluation.Teaching practice indicates that the reform effectively enhances students professional application skills,learning experience,and scientific literacy,facilitating a shift from"tool operation"to"problem-solving"capabilities.This study provides a reference model for the reform of bioinformatics experimental teaching in local universities.
基金Education Department of Hainan Province(Hnjg2026-121)Education Reform Research Project of Hainan Tropical Ocean University(RHYxgnw2026-03)+2 种基金Education Reform Research Project of Hainan Tropical Ocean University(RHYxgnw2026-04)Education Reform Research Project of Hainan Tropical Ocean University(RHYjg2026-18)Education Reform Research Project of Hainan Tropical Ocean University(RHYjg2025-10)。
摘要The deep integration of digitalization and intelligence presents unprecedented challenges to traditional teaching models.To address common issues such as fragmented knowledge systems,weak practical links,insufficient personalized cultivation,and single evaluation mode,this study constructs a systematic reform framework of“concept-technology empowerment-mechanism innovation”based on the concept of digital-intelligence integration and vocational-undergraduate collaborative education.It proposes a four-dimensional implementation path:“driven by dynamic knowledge graphs,by project-flow simulation,supported by AI-human collaborative teaching,and guaranteed by an integrated practical teaching system.”The research specifically focuses on the construction of a higher vocational-undergraduate integrated practical teaching system,forming a progressive practical teaching closed loop of“basic skill training-comprehensive ability cultivation-innovative ability stimulation”through the construction of a cross-stage,cross-disciplinary,virtual-real combined practical platform.The results show that this system can effectively promote the transformation of theoretical knowledge into practical ability and enhance students’comprehensive literacy and innovative spirit,providing a replicable systematic solution for higher education teaching reform under higher vocational-undergraduate cooperation.
基金Sichuan Province 2025 High-Quality Educational and Teaching Resource Construction Project-High-Quality Textbook Cases for Professional Degree Graduate Programs(Rong Li)。
摘要Purpose:This research sets out to explore the practical application value of an innovative teaching mode that organically combines evidence-based medicine(EBM)with artificial intelligence(AI),and analyze its application effect on undergraduate medical students during their ophthalmology internship.Methods:This research team independently built a multi-functional online teaching platform integrating EBM and AI technologies,which incorporates specialized evidence resource libraries,AI auxiliary diagnosis tools,and simulated clinical case modules.A total of 30 fifth-year clinical undergraduates receiving ophthalmology internship training were enrolled as research subjects and randomly assigned into two groups with 15 participants each.The experimental group adopted the newly developed EBM-AI integrated teaching method,while the control group received the conventional offline teaching mode.Multiple indicators were adopted to evaluate the teaching effect,covering students’professional theoretical reserves,EBM and AI-related comprehensive abilities,clinical decision-making level,autonomous learning enthusiasm,and subjective evaluation of teaching quality.Results:Before the intervention,there was no statistical difference in the basic ophthalmology knowledge reserve between the two groups(P>0.05).After the implementation of different teaching schemes,the experimental group outperformed the control group in all evaluation indicators.To be specific,the experimental group obtained higher scores in overall theoretical assessment(86.12±4.05 vs.74.93±5.62,P<0.001)and EBM/AI specialized knowledge test(36.25±2.31 vs.26.80±3.17,P<0.001).Meanwhile,the group also achieved better results in the Script Concordance Test(SCT)for clinical decision-making ability(81.60±5.24 vs.63.87±6.08,P<0.001).In terms of learning initiative,the weekly self-study duration of students in the experimental group was obviously longer than that of the control group(4.02±0.71 vs.1.68±0.44,P<0.001).Additionally,the student satisfaction rate of the new teaching model reached 93.3%,which was notably higher than 73.3%of the traditional teaching group(P=0.031).Conclusion:The integrated teaching model combining EBM and AI can effectively help interns consolidate EBM and AI professional knowledge,optimize clinical case analysis and decision-making capabilities,and stimulate their enthusiasm for independent learning.Importantly,the new teaching method will not affect students’mastery of basic ophthalmology knowledge.This optimized teaching scheme can serve as a reliable reference for promoting the innovative reform of modern ophthalmology higher education.