期刊文献+
任意字段
题名或关键词
题名
关键词
摘要
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息
共找到95篇文章
< 1 2 … 5 >
每页显示 20 50 100
已选0条
引用分析
参考文献
引证文献
 统计分析
检索结果
已选文献
显示方式：
Adding implantable cardioverter-defibrillator to cardiac resynchronization therapy in patients with non-ischemic cardiomyopathy:a systematic review and meta-analysis with focus on elderly subpopulation 认领 引用
1
作者 Vanda Devesa Neto Gonçalo Costa +1 位作者 Luís Ferreira Santos Rogério Teixeira 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2025年第9期775-783,共9页
BACKGROUND Cardiac resynchronization therapy(CRT)has been a major therapeutic advancement for patients with heart failure and electrical dyssynchrony.While CRT improves symptoms,reduces hospitalizations,and enhances s... BACKGROUND Cardiac resynchronization therapy(CRT)has been a major therapeutic advancement for patients with heart failure and electrical dyssynchrony.While CRT improves symptoms,reduces hospitalizations,and enhances survival,the role of implantable cardioverter-defibrillators(ICDs)alongside CRT in patients with non-ischemic cardiomyopathy(NICM)remains controversial.To evaluate and compare the outcomes of CRT with ICD(CRT-D)versus CRT with pacemaker-only(CRT-P)in individuals diagnosed with NICM,with a specific focus on the elderly.METHODS A comprehensive search of PubMed,Embase,and the Cochrane Central Register of Controlled Trials was conducted in January 2024.Studies comparing CRT-D and CRT-P in patients with NICM were included,with subgroup analyses focusing on patients aged 75 years and older.RESULTS Twelve studies,including two randomized clinical trials,with a total of 62,145 patients and 16,754 pooled death events(9,171 in CRT-D and 7,583 in CRT-P),were analyzed.CRT-D was associated with a significantly lower risk of all-cause mortality compared to CRT-P(pooled OR=0.72;95%CI:0.61-0.85;P<0.01),with significant heterogeneity(I2=83%).RCT subgroup analysis,was not statistically significant(pooled OR=0.82;95%CI:0.64-1.06;P=0.41;I2=0%).In patients older than 75 years,no significant difference in mortality risk was observed(pooled OR 0.96;95%CI:0.81-1.15;I2=39%).CONCLUSION Our meta-analysis suggests that the addition of ICD therapy to CRT in patients with NICM significantly reduces all-cause mortality.However,this benefit does not extend to cardiovascular mortality,likely due to the primary role of ICDs in preventing sudden cardiac death rather than other causes such as progressive heart failure.The survival advantage of CRT-D is most pronounced in younger patients,with those over 75 years of age deriving less benefit.This highlights the importance of careful patient selection,considering age and comorbidities,when deciding on ICD implantation in NICM patients. 展开更多
关键词 Cardiac Resynchronization Therapy Implantable Cardioverter Defibrillator cardiac resynchronization therapy crt Mortality Non Ischemic Cardiomyopathy Elderly Meta Analysis heart failure electrical dyssynchronywhile
暂未订购 下载PDF
High sensitivity C-reactive protein and cardfiac resynchronization therapy in patients with advanced heart failure 认领 引用 被引量：11
2
作者 Chi CAI Wei HUA +5 位作者 Li-Gang DING Jing WANG Ke-Ping CHEN Xin-Wei YANG Zhi-Min LIU Shu ZHANG 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2014年第4期296-302,共7页
Background The data on the prognostic values of high sensitivity C-reactive protein(hsCRP)levels in patients with advanced symp-tomatic heart failure(HF)receiving cardiac resynchronization therapy(CRT)are scarce.The a... Background The data on the prognostic values of high sensitivity C-reactive protein(hsCRP)levels in patients with advanced symp-tomatic heart failure(HF)receiving cardiac resynchronization therapy(CRT)are scarce.The aim of present study was to investigate the association of serum hsCRP levels with left ventricle reverse remodeling after six months of CRT as well as long-term outcome.Methods A total of 232 CRT patients were included.The assessment of hsCRP values,clinical status and echocardiographic data were performed at baseline and after six months of CRT.Long-term follow-up included all-cause mortality and hospitalizations for HF.Results During the mean follow-up periods of 31.3±31.5 months,elevated hsCRP(〉3 mg/L)prior to CRT was associated with a significant 2.39-fold increase(P=0.006)in the risk of death or HF hospitalizations.At 6-month follow-up,patients who responded to CRT showed significant reductions or maintained low in hsCRP levels(–0.5±4.1 mg/L reduction)compared with non-responders(1.7±6.1 mg/L increase,P=0.018).Com-pared with patients in whom 6-month hsCRP levels were reduced or remained low,patients in whom 6-month hsCRP levels were increased or maintained high experienced a significantly higher risk of subsequent death or HF hospitalizations(Log-rank P〈0.001).The echocardio-graphic improvement was also better among patients in whom 6-month hsCRP levels were reduced or remained low compared to those in whom 6-month hsCRP levels were raised or maintained high.Conclusions Our findings demonstrated that measurement of baseline and follow-up hsCRP levels may be useful as prognostic markers for timely potential risk stratification and subsequent appropriate treatment strategies in patients with advanced HF undergoing CRT. 展开更多
关键词 Cardiac resynchronization therapy Clinical outcome Heart failure High sensitivity C-reactive protein
暂未订购 下载PDF
Predictors of super-response to cardiac resynchronization therapy: the significance of heart failure medication, pre-implant left ventricular geometry and high percentage of biventricular pacing 认领 引用 被引量：5
3
作者 Han JIN Min GU +6 位作者 Wei HUA Xiao-Han FAN Hong-Xia NIU Li-Gang DING Jing WANG Cong XUE Shu ZHANG 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2017年第12期737-742,共6页
Background Super-responders （SRs） are defined as patients who show crucial cardiac function improvement after cardiac resynchro- nization therapy （CRT）. The purpose of this study is to identify and validate predic... Background Super-responders （SRs） are defined as patients who show crucial cardiac function improvement after cardiac resynchro- nization therapy （CRT）. The purpose of this study is to identify and validate predictors of SRs after CRT. Methods This study enrolled 201 patients who underwent CRT during the period from 2010 to 2014. Clinical and echocardiographic evaluations were conducted before CRT and 6 months after. Patients with a decrease in New York Heart Association （NYHA） fimctional class 〉 1, a decrease in left ventricular end-systolic volume （LVESV） ≥ 15%, and a final left ventricular ejection fraction （LVEF） ≥ 45% were classified as SRs. Results 29% of the 201 patients who underwent CRT were identified as SRs. At baseline, SRs had significantly smaller left atrial diameter （LAD）, LVESV, left ventricular end-diastolic volume （LVEDV） and higher LVEF than the non-super-responders （non-SRs）. The percentage of patients using angiotensin-converting enzyme inhibitors or angiotensin receptor blockers （ACEI/ARB） was higher in SRs than non-SRs. Most SRs had Biventricular （BiV） pacing percentage greater than 98% six months after CRT. In the multivariate logistic regression analysis, the independ- ent predictors of SRs were lower LVEDV [odd ratios （OR）： 0.93; confidence intervals （CI）： 0.90-0.97], use of ACEI/ARB （OR： 0.33; CI： 0.13~3.82） and BiV pacing percentage greater than 98% （OR： 0.29; CI： 0.16~.87）. Conclusion Patients with a better compliance of ACEI/ARB and a less ectatic ventricular geometry before CRT tends to have a greater probability of becoming SRs. Higher percentage of BiV pacing is essential for becoming SRs. 展开更多
关键词 Biventricular pacing Cardiac resynchronization therapy Heart failure Super-responders
暂未订购 下载PDF
Left univentricular pacing for cardiac resynchronization therapy using rate-adaptive atrioventricular delay 认领 引用 被引量：4
4
作者 Li-Jin PU Yu WANG +9 位作者 Lu-Lu ZHAO Tao GUO Shu-Min LI Bao-Tong HUA Ping YANG Jun YANG Yan-Zhou LU Liu-Qing YANG Ling ZHAO Hai-Yun LUO 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2017年第2期118-126,共9页
Objective To evaluate left univentricular （LUV） pacing for cardiac resynchronization therapy （CRT） using a rate-adaptive atrioven- tricular delay （RAAVD） algorithm to track physiological atrioventricular delay ... Objective To evaluate left univentricular （LUV） pacing for cardiac resynchronization therapy （CRT） using a rate-adaptive atrioven- tricular delay （RAAVD） algorithm to track physiological atrioventricular delay （AVD）. Methods A total of 72 patients with congestive heart failure （CHF） were randomized to RAAVD LUV pacing versus standard biventricular （BiV） pacing in a 1 ： 1 ratio. Echocardiography was used to optimize AVD for both groups. The effects of sequential BiV pacing and LUV pacing with optimized A-V （right atrio-LV） delay using an RAAVD algorithm were compared. The standard deviation （SD） of the S/R ratio in lead VI at five heart rate （HR） segments （Rs/R-SD5）, defined as the ＂tracking index,＂ was used to evaluate the accuracy of the RAAVD algorithm for tracking physiological AVD. Results TheQRS complex duration （132 ± 9.8 vs. 138± 10ms, P 〈 0.05）, the time required for optimization （21 ±5 vs. 50±8min, P〈 0.001）, the mitral regurgitant area （1.9 ± 1.1 vs. 2.5 ± 1.3 em2, P 〈 0.05）, the interventricular mechanical delay time （60.7 ± 13.3 ms vs. 68.3 ± 14.2 ms, P 〈 0.05）, and the average annual cost （13,200 ± 1000 vs. 21,600 ± 2000 RMB, P 〈 0.001） in the RAAVD LUV pacing group were significantly less than those in the standard BiV pacing group. The aortic valve velocity-time integral in the RAAVD LUV pacing group was greater than that in the standard BiV pacing group （22.7 ± 2.2 vs. 21.4 ± 2.1 cm, P 〈 0.05）. The Rs/R-SD5 was 4.08 ± 1.91 in the RAAVD LUV pacing group, and was significantly negatively correlated with improved left ventricular ejection fraction （LVEF） （ALVEF, Pearson＇s r = -0.427, P = 0.009）, and positively correlated with New York Heart Association class （Spearman＇s r - 0.348, P 0.037）. Conclusions RAAVD LUV pacing is as effective as standard BiV pacing, can be more physiological than standard BiV pacing, and can de- crease the average annual cost of CRT. 展开更多
关键词 Cardiac resynchronization therapy Congestive heart failure Left univentricular pacing Rate adaptive atrio-ventricular delay
暂未订购 下载PDF
Effect of serum γ-glutamyltranferase and albumin levels on the response to cardiac resynchronization therapy in the elderly 认领 引用 被引量：3
5
作者 Maciej Kubala Alexis Hermida +6 位作者 Otilia Buiciuc Pierre-Marc Lallemand Geneviève Bertaina Frédéric Anselme Didier Klug Momar Diouf Jean-Sylvain Hermida 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2020年第6期313-320,共8页
Background Several liver function tests have been identified as predictors of hospitalization for heart failure(HF) and death in patients with chronic HF. The relationship between serum γ-glutamyltranferase(GGT) and ... Background Several liver function tests have been identified as predictors of hospitalization for heart failure(HF) and death in patients with chronic HF. The relationship between serum γ-glutamyltranferase(GGT) and albumin(SA) levels with the response to cardiac resynchronization therapy(CRT) has not been reliably determined. The aim of the study was to evaluate the impact of liver function tests on the results of CRT in the elderly. Methods Baseline GGT and SA were assessed before CRT device implantation in the elderly(> 70-year-old) patients. The endpoints were:(1) CRT response defined as > 5% left ventricular ejection fraction improvement and no hospitalization for HF or cardiovascular death;(2) hospitalizations;and(3) mortality. Results Eighty of 138(58%) included patients were responders at nine months. Compared to responders, the SA levels were not significantly different(35.1 ± 5.4 vs. 33.6 ± 5.5 g/L, P = 0.103);but the GGT levels, higher(81.6 ± 69.3 vs. 54.7 ± 49.6 U/L, P = 0.013) in non-responders to CRT. GGT level was independently associated with non-response to CRT(P < 0.001, OR = 0.17;95% CI: 0.08–0.38, P < 0.001). GGT cut-off value ≥ 55 U/L was highly predictive of non-response [AUC = 0.65, 64% Sensitivity, 69% Specificity(95% CI: 0.56–0.74)]. GGT ≥ 55 U/L was also associated with higher risk of hospitalization for atrial fibrillation(AF)(95% vs. 83%, P = 0.024). Both SA and GGT had no impact on overall(P = 0.220, P = 0.723) mortality. Conclusions Higher level of GGT is an independent predictor of non-response to CRT in patients over age 70 years and is associated with higher risk of hospitalization for AF. Baseline serum levels of albumin and GGT and have no impact on mortality in elderly patients undergoing CRT. 展开更多
关键词 Cardiac resynchronization therapy Heart failure Liver enzymes The elderly
暂未订购 下载PDF
Cardiac resynchronization therapy for heart failure induced by left bundle branch block after transcatheter closure of ventricular septal defect 认领 引用 被引量：3
6
作者 Rong-Zeng DU Jun QIAN +6 位作者 Jun WU Yi LIANG Guang-Hua CHEN Tao SUN Ye ZHOU Yang ZHAO Jin-Chuan YAN 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2014年第4期357-362,共6页
A 54-year-old female patient with congenital heart disease had a persistent complete left bundle branch block three months after closure by an Amplatzer ventricular septal defect occluder.Nine months later,the patient... A 54-year-old female patient with congenital heart disease had a persistent complete left bundle branch block three months after closure by an Amplatzer ventricular septal defect occluder.Nine months later,the patient suffered from chest distress,palpitation,and sweating at daily activities,and her 6-min walk distance decreased significantly(155 m).Her echocardiography showed increased left ventricular end-diastolic diameter with left ventricular ejection fraction of 37%.Her symptoms reduced significantly one week after received cardiac resynchronization therapy.She had no symptoms at daily activities,and her echo showed left ventricular ejection fraction of 46%and 53%.Moreover,left ventricular end-diastolic diameter decreased 6 and 10 months after cardiac resynchronization therapy,and 6-min walk dis-tance remarkably increased.This case demonstrated that persistent complete left bundle branch block for nine months after transcatheter closure with ventricular septal defect Amplatzer occluder could lead to left ventricular enlargement and a significant decrease in left ventricular systolic function.Cardiac resynchronization therapy decreased left ventricular end-diastolic diameter and increased left ventricular ejection fraction,thereby improving the patient’s heart functions. 展开更多
关键词 Ventricular septal defect Amplatzer occluder Left bundle branch block Heart failure Cardiac resynchronization therapy
暂未订购 下载PDF
The Temporal Relation between Cardiomyopathy and LBBB and Response to Cardiac Resynchronization Therapy:Case Series and Literature Review 认领 引用 被引量：2
7
作者 Sanshuai Chang Yi He +8 位作者 Hui Wang Fei Guo Qiang Lv Junping Kang Rong Bai Xiaohui Liu Xin Du Changsheng Ma Jianzeng Dong 《Cardiovascular Innovations and Applications》 2020年第1期163-172,共10页
Background:Left bundle branch block(LBBB)-induced cardiomyopathy has been proposed,but the association between LBBB and cardiac resynchronization therapy(CRT)response remains unclear and practical criteria for selecti... Background:Left bundle branch block(LBBB)-induced cardiomyopathy has been proposed,but the association between LBBB and cardiac resynchronization therapy(CRT)response remains unclear and practical criteria for selecting CRT candidates are needed.Methods:One hundred and seventeen consecutive heart failure patients were reviewed,24 of whom received CRT.Only two patients had a clear temporal relation between cardiomyopathy and LBBB.Results:Compared with the patient with“cardiomyopathy-induced LBBB,”the patient with“LBBB-induced cardiomyopathy”had higher left ventricular(LV)wall thickness,higher LV wall thickening rate,higher peak circumferential strain,and longer peak circumferential strain delay.The LV deformation patterns in the two patients were obviously distinct on cardiovascular magnetic resonance tissue tracking.During follow-up,the patient with LBBB-induced cardiomyopathy had a good response to CRT(LV ejection fraction 23 before CRT vs.30%at 6 months vs.29 at 12 months vs.32%at 18 months;LV end-diastolic diameter 77 mm before CRT vs.66 mm at 6 months vs.62 mm at 12 months vs.63 mm at 18 months),and the other patient had no response to CRT(LV ejection fraction 29 before CRT vs.29%at 6 months vs.26 at 12 months vs.22%at 24 months;LV end-diastolic diameter 85 mm before CRT vs.88 mm at 6 months vs.85 mm at 12 months vs.84 mm at 24 months).Conclusion:The temporal relation between cardiomyopathy and LBBB could be a determinant for CRT response.Cardiovascular magnetic resonance tissue tracking may be a useful tool to identify the chronological order and a principal consideration for selecting candidates for CRT.Larger prospective clinical trials are needed to study the prevalence of,time course of,and risk factors for LBBB-induced cardiomyopathy. 展开更多
关键词 left bundle branch block cardiomyopathy heart failure cardiovascular magnetic resonance cardiac resynchronization therapy
暂未订购 下载PDF
Transvenous versus open chest lead placement for resynchronization therapy in patients with heart failure: comparison of ventricular electromechanical synchronicity 认领 引用 被引量：2
8
作者 Hai-Bo ZHANG Xu MENG +5 位作者 Jie HAN Yan LI Ye ZHANG Teng-Yong JIANG Ying-Xin ZHAO Yu-Jie Zhou 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2017年第4期261-265,共5页
Background Transvenous lead placement is the standard approach for left ventricular （LV） pacing in cardiac resynchronization ther- apy （CRT）, while the open chest access epicardial lead placement is currently the ... Background Transvenous lead placement is the standard approach for left ventricular （LV） pacing in cardiac resynchronization ther- apy （CRT）, while the open chest access epicardial lead placement is currently the most frequently used second choice. Our study aimed to compare the ventricular electromechanical synchronicity in patients with heart failure after CRT with these two different LV pacing tech- niques. Methods We enrolled 33 consecutive patients with refractory heart failure secondly to dilated cardiomyopathy who were eligible for CRT in this study. Nineteen patients received transvenous （TV group） while 14 received open chest （OP group） LV lead pacing. Intraand inter-ventricular electromechanical synchronicity was assessed by tissue Doppler imaging （TDI） before and one year after CRT procedure. Results Before CRT procedure, the mean QRS-duration, maximum time difference to systolic peak velocity among 12 left ventricle segments （LV Ts-12）, standard deviation of time difference to systolic peak velocity of 12 left ventricle segments （LV Ts-SD）, and inter-ventficular mechanical delay （IVMD） in OP and TV group were 166 ± 17 ms and 170 ± 21 ms, 391 ±42 ms and 397 ± 36 ms, 144 ± 30 ms and 148 ± 22 ms, 58 ± 25 ms and 60 ± 36 ms, respectively （all P 〉 0.05）. At one year after the CRT, the mean QRS-duration, LV Ts-12, LV Ts-SD, and IVMD in TV and OP group were 128 ± 14 ms and 141 ± 22 ms （P = 0.031）, 136 ± 37 ms and 294 ± 119 ms （P = 0.023）, 50± 22 ms and 96 ± 34 ms （P = 0.015）, 27 ± 11 ms and 27 ± 26 ms （P = 0.86）, respectively. The LV lead implantation procedure time was 53.4±16.3 rain for OP group and 136 ± 35.1 min for TV group （P = 0.016）. The mean LV pacing threshold increased significantly from 1.7 ± 0.6 V/0.5 ms to 2.3 ± 1.6 V/0.5 ms （P 〈 0.05） in TV group while it remained stable in the OP group. Conclusions Compared to conventional endovascular approach, open chest access of LV pacing for CRT leads to better improvement of the intraventricular synchronization. 展开更多
关键词 Heart failure Resynchronization Tissue Doppler imaging
暂未订购 下载PDF
The role of electrocardiography in the elaboration of a new paradigm in cardiac resynchronization therapy for patients with nonspecific intraventricular conduction disturbance 认领 引用 被引量：2
9
作者 Andras Vereckei Gabor Katona +3 位作者 Zsuzsanna Szelenyi Gabor Szenasi Balint Kozman Istvan Karadi 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2016年第2期118-125,共8页
Cardiac resynchronization therapy （CRT） is associated with a favorable outcome only in patients with left bundle branch block （LBBB） pattern and in patients with a QRS duration 〉 150 ms, in patients with non-LBBB... Cardiac resynchronization therapy （CRT） is associated with a favorable outcome only in patients with left bundle branch block （LBBB） pattern and in patients with a QRS duration 〉 150 ms, in patients with non-LBBB pattern with a QRS duration of 120-150 ms usually is not beneficial. After adjusting for QRS duration, QRS morphology was no longer a determinant of the clinical response to CRT. In contrast to the mainstream view, we hypothesized that the unfavorable CRT outcome in patients with non-LBBB and a QRS duration of 120-150 ms is not due to the QRS morphology itself, but to less dyssynchrony and unfavorable patient characteristics in this subgroup, such as more ischemic etiology and greater prevalence of male patients compared with patients with LBBB pattern. Further, the current CRT technique is devised to eliminate the dyssynchrony present in patients with LBBB pattern and inappropriate to eliminate the dyssynchrony in patients with non-LBBB pattern. We also hypothesized that electrocardiography may also provide information about the presence of interventricular and left intraventricular dyssynchrony and the approximate location of the latest activated left ventricular （LV） region. To this end, we devised new ECG criteria to estimate interventricular and LV intraventricular dyssynchrony and the approximate location of the latest activated LV region. Our preliminary data demonstrated that the latest activated LV region in patients with nonspecific intraventricular conduction disturbance （NICD） pattern might be at a remote site from that present in patients with LBBB pattern, which might necessitate the invention of a novel CRT technique for patients with NICD pattern. The application of the new interventricular and LV intraventricular dyssynchrony ECG criteria and a potential novel CRT technique might decrease the currently high nonresponder rate in patients with NICD pattern. 展开更多
关键词 Cardiac resynchronization therapy Electrocardiography Heart failure
暂未订购 下载PDF
Left bundle branch pacing with optimization of cardiac resynchronization treatment:A case report 认领 引用 被引量：2
10
作者 Deng-Hong Zhang Ming-Jian Lang +2 位作者 Gang Tang Xiao-Xiao Chen Hong-Fei Li 《World Journal of Clinical Cases》 SCIE 2020年第18期4266-4271,共6页
BACKGROUND Cardiac resynchronization therapy(CRT)is a well-established therapy for patients with cardiomyopathy.CASE SUMMARY The patient underwent left bundle branch area and left ventricular(reaching the left ventric... BACKGROUND Cardiac resynchronization therapy(CRT)is a well-established therapy for patients with cardiomyopathy.CASE SUMMARY The patient underwent left bundle branch area and left ventricular(reaching the left ventricular lateral vein through the coronary sinus)pacing.The optimal CRT was performed under the right bundle branch of the patient by adjusting the optimal a-v and v-v interphases to achieve the maximal benefit of the treatment.CONCLUSION The patient was diagnosed with left bundle branch block and heart failure.A left bundle branch area pacemaker assisted in correcting the complete left bundle branch block.However,the shorter QRS wave shape after pacemaker implantation through the left bundle branch area indicated a complete right bundle branch block pattern.Hence,the left bundle branch area pacemaker is not always considered as the optimal treatment.The left bundle branch pacing with the optimization of cardiac resynchronization treatment may serve as a new CRT strategy. 展开更多
关键词 Cardiac resynchronization therapy Cardiomyopathy Left bundle branch Case report
暂未订购 下载PDF
Reversal of Wolff-Parkinson-White Syndrome induced dilated cardiomyopathy via resynchronization and subsequent accessory pathway ablation 认领 引用 被引量：1
11
作者 Long-Bin LIU Chang-Zuan ZHOU +4 位作者 Hui LIN Li-Ping MENG Chang BIAN Yu ZHANG Hang-Yuan GUO 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2017年第10期654-656,共3页
Recurrent or incessant tachycardia is frequently found in symptomatic Wolff-Parkinson-White （WPW） syndrome, leading to ventricular dysfunction, dilated cardiomyopathy （DCM） and heart failure in infants and childre... Recurrent or incessant tachycardia is frequently found in symptomatic Wolff-Parkinson-White （WPW） syndrome, leading to ventricular dysfunction, dilated cardiomyopathy （DCM） and heart failure in infants and children.[1] Recently, Winter, et al.[2] report that WPW syndrome could provoke many kinds of cardiac dysfunction, leading to remodeling and progressive ventricular dilatation through pre-excita- tion-related dyssynchrony, even without arrhythmia. 展开更多
关键词 Catheter ablation Cardiomyopathy Cardiac resynchronization therapy
暂未订购 下载PDF
Clinical outcome of cardiac resynchronization therapy in dilated-phase hypertrophic cardiomyopathy 认领 引用 被引量：1
12
作者 Min GU Han JIN +7 位作者 Wei HUA Xiao-Han FAN Hong-Xia NIU Tao TIAN Li-Gang DING Jing WANG Cong XUE Shu ZHANG 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2017年第4期238-244,共7页
Backgrounds Clinical trials have demonstrated that cardiac resynchronization therapy （CRT） is effective in patients with ＂non-is- chemic cardiomyopathy＂. However, patients with dilated-phase hypertrophic cardiomyo... Backgrounds Clinical trials have demonstrated that cardiac resynchronization therapy （CRT） is effective in patients with ＂non-is- chemic cardiomyopathy＂. However, patients with dilated-phase hypertrophic cardiomyopathy （DHCM） have been generally excluded from such trials. We aimed to compare the clinical outcome of CRT in patients with DHCM, idiopathic dilated cardiomyopathy （IDCM）, or ischemic cardiomyopathy （ICM）. Methods A total of 312 consecutive patients （DHCM： n = 16; IDCM： n = 231; ICM： n = 65） undergoing CRT in Fuwai hospital were studied respectively. Response to CRT was defmed as reduction in left ventricular end-systolic volume （LVESV） _〉 15% at 6-month follow-up. Results Compared with DHCM, IDCM was associated with a lower total mortality （HR： 0.35, 95% CI： 0.13-0.90）, cardiac mortality （HR： 0.29; 95% CI： 0.11-0.77）, and total mortality or heart failure （HF） hospitalizations （HR： 0.34, 95% CI： 0.17-0.69）, independent of known confounders. Compared with DHCM, the total mortality, cardiac mortality and total mortality or HF hospitalizations favored ICM but were not statistically significant （HR： 0.59, 95% CI： 0.22-1.61; HR： 0.59, 95% CI： 0.21-1.63; HR： 0.54, 95% CI： 0.26-1.15; respectively）. Response rate to CRT was lower in the DHCM group than the other two groups although the differences didn＇t reach statistical significance. Conclusions Compared with IDCM, DHCM was associated with a worse outcome after CRT. The clinical outcome of DHCM patients receiving CRT was similar to or even worse than that of ICM patients. These indicate that DHCM behaves very differently after CRT. 展开更多
关键词 Cardiac resynchronization therapy Dilated-phase hypertrophic cardiomyopathy Idiopathic dilated cardiomyopathy Ischemic cardiomyopathy
暂未订购 下载PDF
Predictors of persistence of functional mitral regurgitation after cardiac resynchronization therapy:Review of literature 认领 引用 被引量：1
13
作者 Eleonora Russo Giulio Russo +1 位作者 Maurizio Braccio Mauro Cassese 《World Journal of Cardiology》 2022年第3期170-176,共7页
Functional mitral regurgitation is a common finding among heart failure patients with ischemic and non-ischemic dilated cardiomyopathies.The presence of moderate or severe mitral regurgitation is associated with highe... Functional mitral regurgitation is a common finding among heart failure patients with ischemic and non-ischemic dilated cardiomyopathies.The presence of moderate or severe mitral regurgitation is associated with higher morbidity and mortality.Heart failure patients meeting electrocardiogram and left ventricle function criteria are good candidates for cardiac resynchronization therapy,which may reduce the degree of functional mitral regurgitation in the short and long term,specifically targeting myocardial dyssynchrony and inducing left ventricle reverse remodeling.In this article,we analyze data from the literature about predictors of mitral regurgitation improvement after cardiac resynchronization therapy implantation. 展开更多
关键词 Functional mitral regurgitation Cardiac resynchronization therapy Predictors Mitral regurgitation improvement Dyssynchrony
暂未订购 下载PDF
Intermediate-term mortality and incidence of ICD therapy in octogenarians after cardiac resynchronization therapy 认领 引用 被引量：2
14
作者 Heval Mohamed Kelli Faisal MMerchant +3 位作者 Andenet Mengistu Mary Casey Michael Hoskins Mikhael FEl-Chami 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2014年第3期180-184,共5页
Background Clinical outcomes of cardiac resynchronization therapy （CRT） in patients over the age of 80 have not been well de-scribed.MethodsWe retrospectively identified 96 consecutive patients≥ 80 years old who un... Background Clinical outcomes of cardiac resynchronization therapy （CRT） in patients over the age of 80 have not been well de-scribed.MethodsWe retrospectively identified 96 consecutive patients≥ 80 years old who underwent an initial implant or an upgrade to CRT, with or without defibrillator （CRT-Dvs. CRT-P）, at our institution between January 2003 and July 2008. The control cohort consisted of 177 randomly selected patients 〈 80 years old undergoing CRT implant during the same time period. The primary efficacy endpoint was all-cause mortality at 36 months, assessed by Kaplan-Meier time to first event curves.Results In the octogenarian cohort, mean age at CRT implant was 83.1 ± 2.9 yearsvs. 60.1 ± 8.8 years among controls （P 〈 0.001）. Across both groups, 70% were male, mean left ventricular ejection fraction （LVEF） was 24.8% ± 14.1% and QRS duration was 154 ± 24.8 ms, without significant differences between groups. Octo-genarians were more likely to have ischemic cardiomyopathy （74%vs. 37%,P 〈 0.001） and more likely to undergo upgrade to CRT instead of an initial implant （42%vs. 19%,P 〈 0.001）. The rate of appropriate defibrillator shocks was lower among octogenarians （14%vs. 27%,P = 0.02） whereas the rate of inappropriate shocks was similar （3%vs. 6%,P = 0.55）. At 36 months, there was no significant difference in the rate of all-cause mortality between octogenarians （11%） and controls （8%,P = 0.381）.ConclusionAppropriately selected octogenarians who are candidates for CRT have similar intermediate-term mortality compared to younger patients receiving CRT. 展开更多
关键词 Octogenarians Cardiac resynchronization therapy Implantable cardioverter-defibrillator
暂未订购 下载PDF
Clinical efficacy and predictor of cardiac resynchronization therapy on left bundle branch block-associated heart dysfunction 认领 引用 被引量：2
15
作者 梁远红 陈泗林 +5 位作者 林纯莹 费洪文 刘烈 陈东骊 詹贤章 吴书林 《South China Journal of Cardiology》 CAS 2013年第4期230-236,共7页
Background Left bundle branch block （LBBB） results in an altered pattern of left ventricular （LV） activation and subsequent contraction. Cardiac synchrony and cardiac function are deteriorated by LBBB. However, th... Background Left bundle branch block （LBBB） results in an altered pattern of left ventricular （LV） activation and subsequent contraction. Cardiac synchrony and cardiac function are deteriorated by LBBB. However, the effect of LBBB history on progressive heart dysfunction and clinical efficacy of cardiac resynchronization therapy （CRT） in such patients are not clear. In this study we explore the clinical efficacy and predictor of cardiac resynchronization therapy in LBBB heart dysfunction. Methods Twenty-seven LBBB patients with severe heart failure were treated with CRT. Twenty-six LBBB patients without CRT served as control. During 6 months follow-up, ECG, plasma NT-proBNP and echocardiogram indexes were measured. Results Compared with baseline, NYHA functional class of 23 patients （85.2%） was improved in CRT group. Compared with baseline and control, QRS duration （QRSd） was significantly more narrow （P = 0.023, P = 0.019）, NT-proBNP was significantly lower （P = 0.011,P = 0.009）, ventricular septal to left ventricular posterior wall delay time and left ventricular dyssynchrony index （Ts-SD） were significantly worse （P 〈 0.05）; left ventricular ejection fraction, left ventricular end-systolic volume, mitral regurgitation area were significantly improved in CRT group （P 〈 0.05）. when the LBBB history was I〉 2 years and QRSd I〉 155 ms, the sensitivity and specificity of CRT super-response were 53.4% and 85.6% respectively. Conclusions CRT can improve the synchronization and hemodynamic of LBBB patients with heart dysfunction, the LBBB history I〉 2 years and QRSd I〉 155 ms are one of the CRT super-response predictors. 展开更多
关键词 cardiac resynchronization therapy left bundle branch block hyperresponse predictors
暂未订购 下载PDF
Left bundle branch pacing set to outshine biventricular pacing for cardiac resynchronization therapy? 认领 引用 被引量：2
16
作者 Akash Batta Juniali Hatwal 《World Journal of Cardiology》 2024年第4期186-190,共5页
The deleterious effects of long-term right ventricular pacing necessitated the search for alternative pacing sites which could prevent or alleviate pacinginduced cardiomyopathy.Until recently,biventricular pacing(BiVP... The deleterious effects of long-term right ventricular pacing necessitated the search for alternative pacing sites which could prevent or alleviate pacinginduced cardiomyopathy.Until recently,biventricular pacing(BiVP)was the only modality which could mitigate or prevent pacing induced dysfunction.Further,BiVP could resynchronize the baseline electromechanical dssynchrony in heart failure and improve outcomes.However,the high non-response rate of around 20%-30%remains a major limitation.This non-response has been largely attributable to the direct non-physiological stimulation of the left ventricular myocardium bypassing the conduction system.To overcome this limitation,the concept of conduction system pacing(CSP)came up.Despite initial success of the first CSP via His bundle pacing(HBP),certain drawbacks including lead instability and dislodgements,steep learning curve and rapid battery depletion on many occasions prevented its widespread use for cardiac resynchronization therapy(CRT).Subsequently,CSP via left bundle branch-area pacing(LBBP)was developed in 2018,which over the last few years has shown efficacy comparable to BiVP-CRT in small observational studies.Further,its safety has also been well established and is largely free of the pitfalls of the HBP-CRT.In the recent metanalysis by Yasmin et al,comprising of 6 studies with 389 participants,LBBPCRT was superior to BiVP-CRT in terms of QRS duration,left ventricular ejection fraction,cardiac chamber dimensions,lead thresholds,and functional status amongst heart failure patients with left bundle branch block.However,there are important limitations of the study including the small overall numbers,inclusion of only a single small randomized controlled trial(RCT)and a small follow-up duration.Further,the entire study population analyzed was from China which makes generalizability a concern.Despite the concerns,the meta-analysis adds to the growing body of evidence demonstrating the efficacy of LBBP-CRT.At this stage,one must acknowledge that the fact that still our opinions on this technique are largely based on observational data and there is a dire need for larger RCTs to ascertain the position of LBBPCRT in management of heart failure patients with left bundle branch block. 展开更多
关键词 Biventricular pacing Cardiac resynchronization therapy Conduction system pacing Left bundle branch-area pacing Left bundle branch block Electromechanical dssynchrony
暂未订购 下载PDF
Cardiac resynchronization therapy: Dire need for targeted left ventricular lead placement and optimal device programming 认领 引用 被引量：1
17
作者 Sokratis Pastromas Antonis S Manolis 《World Journal of Cardiology》 2014年第12期1270-1277,共8页
Cardiac resynchronization therapy(CRT) effected via biventricular pacing has been established as prime therapy for heart failure patients of New York Heart Association functional class Ⅱ, Ⅲ and ambulatory Ⅳ, reduce... Cardiac resynchronization therapy(CRT) effected via biventricular pacing has been established as prime therapy for heart failure patients of New York Heart Association functional class Ⅱ, Ⅲ and ambulatory Ⅳ, reduced left ventricular(LV) function, and a widened QRS complex. CRT has been shown to improve symptoms, LV function, hospitalization rates, and survival. In order to maximize the benefit from CRT and reduce the number of non-responders, consideration should be given to target the optimal site for LV lead implantation away from myocardial scar and close to the latest LV site activation; and also to appropriately program the device paying particular attention to optimal atrioventricular and interventricular intervals. We herein review current data related to both optimal LV lead placement and device programming and their effects on CRT clinical outcomes. 展开更多
关键词 Heart failure Cardiac dyssynchrony Left bundle branch block Cardiac resynchronization therapy Biventricular pacing
暂未订购 下载PDF
Does it make sense evaluating cardiac resynchronization therapy in the elderly regardless of the type of the device? 认领 引用
18
作者 Mehmet Tezcan Omer Uz +1 位作者 Gokhan Degirmencioglu Mustafa Aparci 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2016年第4期371-372,共2页
We read the research article entitled Is cardiac resyn- chronisation therapy feasible, safe and beneficial in the very elderly？ with great interest. The authors emphasized that despite the average age of heart failur... We read the research article entitled Is cardiac resyn- chronisation therapy feasible, safe and beneficial in the very elderly？ with great interest. The authors emphasized that despite the average age of heart failure was 77 years in the general population of UK,patients receiving cardiac re- synchronisation therapy [with pacemaker alone （CRT-P） or with additional defibrillator capabilities （CRT-D）] were on younger ages at 72 and 67 years respectively. In the lights of this data, we agree with the authors that CRT seems to be undemtilized in the elderly patients with heart failure. 展开更多
关键词 Cardiac resynchronization therapy Defibrillator Pacemaker
暂未订购 下载PDF
Cardiac resynchronization in the elderly is beneficial, but could we implant our devices in old patients safer? 认领 引用
19
作者 Evgeny N Mikhaylov Dmitry S Lebedev 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2016年第3期277-278,共2页
We read with interest the article by Olechowski, et aL recently published in the Journal of Geriatric Cardiology. The results of this retrospective analysis of patients under- going cardiac resynchronization therapy ... We read with interest the article by Olechowski, et aL recently published in the Journal of Geriatric Cardiology. The results of this retrospective analysis of patients under- going cardiac resynchronization therapy （CRT） device implantation are in line with previous reports, suggesting that resynchronization therapy in the elderly is feasible and may lead to significant improvement of cardiac function and clinical status. 展开更多
关键词 Cardiac resynchronization therapy Implantable cardioverter-defibrillator Pneumothorax
暂未订购 下载PDF
Cardiac resynchronization therapy in China 认领 引用
20
作者 Wei HUA 《Journal of Geriatric Cardiology》 CAS 2006年第4期248-249,共2页
　　Congestive heart failure (HF) is a major and growing public health problem. The therapeutic approach includes non-pharmacological measures, pharmacological therapy,mechanical devices, and surgery. Despite the bene... 　　Congestive heart failure (HF) is a major and growing public health problem. The therapeutic approach includes non-pharmacological measures, pharmacological therapy,mechanical devices, and surgery. Despite the benefits of optimal pharmacologic therapy, the prognosis is still not ideal. At this time, cardiac resynchronization therapy (CRT)has gained wide acceptance as an alternative treatment for HF patients with conduction delay.1…… 展开更多
关键词 CRT AHA ACC CHF Cardiac resynchronization therapy in China
暂未订购 下载PDF
已选0条
引用分析
参考文献
引证文献
 统计分析
检索结果
已选文献
上一页 1 2 … 5 下一页 到第 页
在线咨询 使用帮助 返回顶部 意见反馈