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Bacillus velezensis activates beneficial soil microorganisms to promote the growth and health of cucumber after soil fumigation 认领 引用 被引量：2
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作者 Xuewen Xie Lida Chen +8 位作者 Shicheng Liu Lixia Yan Na Li Changzong Ding Yanxia Shi Ali Chai Tengfei Fan Baoju Li Lei Li 《Horticultural Plant Journal》 SCIE CAS CSCD 2026年第6期1403-1415,共13页
Cucumber root rot,primarily caused by Fusarium solani,threatens global cucumber production through soil-borne infection,vascular wilt,and yield loss.Soil fumigation with Calcium cyanamide(CaCN2)effectively suppress... Cucumber root rot,primarily caused by Fusarium solani,threatens global cucumber production through soil-borne infection,vascular wilt,and yield loss.Soil fumigation with Calcium cyanamide(CaCN2)effectively suppresses soil-borne pathogens but may impair beneficial soil microbiota.This study investigated the synergistic effects of Bacillus velezensis(ZF336)inoculation on reactivating beneficial soil microbes after CaCN2 fumigation and its role in controlling cucumber root rot caused by F.solani.The physicochemical properties and microbial community structure of the soil and the health of the cucumber plants were investigated.Our findings revealed the following.(Ⅰ)The potential for hydrogen(pH)and the contents of organic matter(OM),nitrate nitrogen(NO3-N)and ammonium nitrogen(NH4-N)significantly increased after combined CaCN2 and ZF336 treatment.(Ⅱ)Combined CaCN2 and ZF336 treatment reduced the relative abundance of Fusarium and increased the relative abundances of the potentially beneficial bacteria Trichoderma and Penicillium in the soil.In addition,B.velezensis promoted the recovery of microbial communities after CaCN2 disinfection.(Ⅲ)Combined CaCN2 and ZF336 treatment improved the activities of carbohydrate enzymes,effectively promoting soil carbon metabolism and increasing the cellulase,hemicellulose and lignin decomposition abilities.In conclusion,CaCN2 combined with B.velezensis stimulated the soil microbial community structure and the activities of specific enzymes and is an effective way to control cucumber root rot disease and improve yield and soil quality. 展开更多
关键词 Cucumber Calcium cyanamide Bacillus velezensis Soil microbial community Function genes Fusarium
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Achievement of an ultra-broadband deep red phosphor K3Ca0.3Y0.7Si2O7:Eu^(2+)(phase 1)for phytochrome matching plant-lighting 认领 引用 被引量：1
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作者 Xiaoshuai Zhang Xi Wang +6 位作者 Tao Yin Xuping Han Panlai Li Xiaoyan Yu Zixuan Wang Chengrun Liu Zhijun Wang 《Journal of Rare Earths》 SCIE EI CAS CSCD 2026年第1期103-111,共9页
The market demand for environmentally controlled agricultural indoor lighting is gradually increasing due to environmental pollution and drastic changes in the natural climate.Generally,matrix K3YSi2O7(phase ... The market demand for environmentally controlled agricultural indoor lighting is gradually increasing due to environmental pollution and drastic changes in the natural climate.Generally,matrix K3YSi2O7(phase 1) is difficult to synthesize compared to K3YSi2O7(phase 2),which has been illustrated by theoretical calculations.In this paper,large quantities of pure phase K3YSi2O7(phase 1) matrix were obtained by the substitution engineering strategy(Ca^(2+)→Y3+).Subsequently,Eu^(2+) was doped to obtain a thermally stable ultra-wideband deep red light-emitting phosphor with an emission band centered at721 nm and a full width at half maximum of 186 nm under 450 nm light excitation.It is noteworthy that compared with K3YSi2O7:Eu(phase 2),K3Ca0.3Y0.7Si2O7:Eu^(2+)(phase 1) is superior in terms of emission wavelength,full width at half maximum,and thermal stability.Furthermore,the spectrum resemblance between its emission spectrum and the photosensitive pigment Pfr was calculated to be 97.5%,which set the stage for subsequent plant lighting applications.Finally,light-emitting diode devices were prepared using K3Ca0.3Y0.7Si2O7:Eu^(2+) phosphor for plant lighting experiments,and plants grown under deep red light emitting diode light show more luxuriant growth.The results show that the phosphor K3Ca0.3Y0.7Si2O7:Eu^(2+) has promising applications in indoor plant culture.Meanwhile,the successful implementation of ion substitution engineering also provides a new strategy for transitions in host systems. 展开更多
关键词 Ion substitution Phase transition Eu2+ions Deep red light-emitting Plant lighting Rare earths
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Complete genome assembly of the Xian rice variety IR64 as a valuable source in genomics and breeding research 认领 引用 被引量：1
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作者 Min Li Tingting Sheng +13 位作者 Linjun Yu Shuyue Zheng Shijiao Li Shuran Zhou Fengcai Wu Fan Zhang Chaopu Zhang Erbao Liu Yingyao Shi Xue Mi Xueru Zhang Zhikang Li Yanru Cui Wensheng Wang 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2026年第3期551-554,共4页
IR64 is an elite Xian/indica variety developed by International Rice Research Institute(IRRl)in 1985,which has been the most widely grown variety and core breeding parent in South/Southeast Asia(Mackill and Khush,2018... IR64 is an elite Xian/indica variety developed by International Rice Research Institute(IRRl)in 1985,which has been the most widely grown variety and core breeding parent in South/Southeast Asia(Mackill and Khush,2018).IR64 has been utilized to develop stress-tolerant(such as drought-adapted and submergenceresistant)near-isogenic lines,underscoring its great potential in agricultural genomics(Tanaka et al.,2020). 展开更多
关键词 Xian rice IR core breeding parent breeding research agricultural genomics tanaka genomics genome assembly stress tolerance
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Efficient and tunable photoluminescence from Dy3+-doped Cs2NaLuCl6double perovskites via Sb3+sensitization 认领 引用
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作者 Guodong Zhang Yue Lu +4 位作者 Yaning Zhao Peipei Dang Hao Suo Zhijun Wang Panlai Li 《Journal of Rare Earths》 SCIE EI CAS CSCD 2026年第7期2010-2018,I0001,共9页
Incorporating rare-earth(RE3+)ions into lead-free halide double perovskites represents a promising str ategy for modulating their optical prope rties through energy transfer mechanisms.In this study,Dy3+ions wer... Incorporating rare-earth(RE3+)ions into lead-free halide double perovskites represents a promising str ategy for modulating their optical prope rties through energy transfer mechanisms.In this study,Dy3+ions were successfully incorporated into Cs2NaLuCl6:Sb3+double perovskites via a facile hydrothermal method.The synthesized crystals not only exhibit intense blue emission originating from self-trapped excitons(STEs)but also display effective Dy3+characteristic emissions,thereby broadening the emission spectrum from the visible to the near-infrared region.The energy transfer from STEs to Dy3+is confirmed and extends across various RE3+ions.Temperature-dependent photoluminescence spectra reveal insights into the excitation and emission processes,as well as thermal quenching mechanism.Additionally,the characteristic emissions of Dy3+demonstrate varied anti-thermal quenching behaviors,indicating the remarkable thermal stability of the synthesized crystals.The thermally coupled sublevels of Dy3+ions are employed to develop optical thermometers with notable sensitivity.Finally,the light-emitting diodes fabricated by encapsulating the optimized samples onto commercial chips highlight the great potential of Dy3+-doped Cs2NaLuCl6:Sb3+materials for photoelectric applications. 展开更多
关键词 Metal halide Sb3+ Rare earths Photoluminescence Energy transfer
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Immunometabolic Reprogramming in Hepatocellular Carcinoma Mechanisms,Biomarkers,and Therapeutic Implications 认领 引用
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作者 Guodong Yu Weiying Ge +6 位作者 Hongliang Yao Xuefeng Bai Jianfei Wu Yuan Wang Jiangtao Bai Yong Cui Jijing Han 《Oncology Research》 SCIE 2026年第7期321-356,共36页
Hepatocellular carcinoma(HCC)develops in a chronically inflamed and dysregulated liver metabolism,in which tumor progression and resistance to treatment are orchestrated by the changes in cellular metabolism and immun... Hepatocellular carcinoma(HCC)develops in a chronically inflamed and dysregulated liver metabolism,in which tumor progression and resistance to treatment are orchestrated by the changes in cellular metabolism and immune control.Growing evidence recognizes immunometabolic reprogramming as the two-way interaction of metabolic processes and immune cell capabilities as one of the major determinants of immune evasion and heterogeneity of treatment response in HCC.The review aims to comprehensively evaluate immunometabolic reprogramming in hepatocellular carcinoma,with a focus on its role in tumor progression,immune regulation,and its potential for biomarker identification and therapeutic targeting.Dysregulated glycolysis,lipid metabolism,amino acid utilization,and mitochondrial dysfunction contribute to remodeling of the tumor microenvironment and defects in antitumor immunity.Immunometabolic biomarkers derived from tumor tissue,immune cell states,circulating and liquid biopsy platforms,and metabolic imaging are critically examined for their clinical relevance and associations with disease outcomes and treatment responses.Besides,the role of different immunometabolic conditions on therapeutic efficacy,specifically within the frames of immune checkpoint-inhibitor-based and combination regimens,is addressed.Altogether,immunometabolic reprogramming is identified as a common framework of biomarker-based stratification and precision therapeutic techniques in hepatocellular carcinoma. 展开更多
关键词 Metabolic reprogramming tumor microenvironment biomarkers immune checkpoint hepatocellular carcinoma
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TMO-based SERS:Dual enhancement mechanisms and multi-functional analytical applications 认领 引用
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作者 Xiaoyu Song Lei Xu +5 位作者 Xiangyu Meng Yuening Wang Mingjian Zhang Aochi Liu Jie Lin Xiaotian Wang 《Chinese Journal of Structural Chemistry》 SCIE CAS CSCD 2026年第2期152-166,共15页
Surface-enhanced Raman scattering(SERS)spectroscopy based on transition metal oxide(TMO)substrates has emerged as a frontier research area,offering distinctive advantages in chemical stability,cost-effectiveness,and t... Surface-enhanced Raman scattering(SERS)spectroscopy based on transition metal oxide(TMO)substrates has emerged as a frontier research area,offering distinctive advantages in chemical stability,cost-effectiveness,and tunable optoelectronic properties compared to conventional noble metal substrates.This review systematically clarifies the dual enhancement mechanisms of TMO-based SERS including charge transfer(CT)resonance at the molecule-semiconductor interface and electromagnetic field amplification induced by localized surface plasmon resonance(LSPR);the two work synergistically to achieve signal amplification.In practical applications,TMO enable multi-scenario analysis via the controllable defect engineering-interfacial CT synergistic mechanism in SERS technology.These scenarios include ultrasensitive detection of biomarkers,dynamic tracking of cellular metabolism,real-time monitoring of environmental pollutants,and mechanistic analysis of catalytic reaction pathways.Nevertheless,critical challenges persist,particularly regarding quantitative reproducibility and long-term stability under operational conditions.This review focuses on discussing the SERS enhancement mecha-nisms of TMO,summarizing their diverse analytical applications across multiple fields,and briefly addressing existing limitations,aiming to provide insights for further advancement in TMO-based SERS research. 展开更多
关键词 Transition metal oxides Surface-enhanced Raman scattering Enhancement mechanisms Defect engineering Analytical applications
Photo-driven upcycling of plastics:pathways to value-added products 认领 引用
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作者 Yachuan Wang Qixuan Wu +7 位作者 Lin Ma Runan Lei Jialin Wang Kai Du Dachao Yuan Yuan Tang Yaguang Li Jinhua Ye 《Science China Chemistry》 SCIE EI CAS CSCD 2026年第7期3286-3302,共17页
Plastic waste faces a serious environmental challenge due to its persistent nature and resource inefficiency in traditional disposal methods.Photo-driven catalytic upcycling technology has emerged as a promising strat... Plastic waste faces a serious environmental challenge due to its persistent nature and resource inefficiency in traditional disposal methods.Photo-driven catalytic upcycling technology has emerged as a promising strategy for converting plastic waste into high-value-added products while utilizing renewable energy sources.This work comprehensively reviews recent advances in photo-driven upcycling of plastics,focusing on photocatalytic and photothermal catalytic plastics upcycling.Based on the distinct mechanisms of photo-oxidation degradation utilizing photo-generated carriers and photothermal depolymerization of plastics,advancements in photo-driven upcycling of diverse plastics are evaluated.Optimized reactor designs to enhance solar thermal conversion efficiency and achieve industrial feasibility for plastics utilization are also summarized and prospected.Guidelines for more accurate evaluation of materials and systems have been proposed to address the limitations and challenges in current plastic photo-driven upcycling research,aiming to provide a reference basis for the plastics recycling economy. 展开更多
关键词 plastic upcycling photocatalysis photothermal catalysis
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Transcriptome and metabolome analysis reveals regulatory network associated with light-independent anthocyanin biosynthesis in blueberry fruit 认领 引用
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作者 Xuyan Li Shouwen Wang +7 位作者 Hongxue Li Fangyun Qian Haiyang Wang Jingying Wang Lulu Zhai Baosheng Shi Junwei Huo Shaomin Bian 《Horticultural Plant Journal》 SCIE CAS CSCD 2026年第3期584-602,共19页
Anthocyanins are vital secondary metabolites contributing to fruit pigmentation and antioxidative properties.While light is a well-known regulator of anthocyanin biosynthesis,the molecular basis of light-independent a... Anthocyanins are vital secondary metabolites contributing to fruit pigmentation and antioxidative properties.While light is a well-known regulator of anthocyanin biosynthesis,the molecular basis of light-independent anthocyanin accumulation remains underexplored.In this study,integrated analysis of metabolome and transcriptome showed that the anthocyanin content in blueberry(Vaccinium corymbosum‘Bluetta’)fruit was slightly decreased by light-impermeable bagging treatment,while anthocyanin biosynthetic genes were transcriptionally inhibited to different levels,suggesting a slight influence of the bagging treatment on anthocyanin accumulation.Further observation showed that fruit bagging did not alter ethylene production but decreased ABA content.Noticeably,two VcMYBA/MYB1s were not transcriptionally altered by the light-impermeable bagging treatment.Consistently,histochemical GUS analysis and pharmacological manipulation suggested light-independent and ethylene-inducible expression of VcMYBA/MYB1.Moreover,WGCNA analysis revealed 3759 genes positively associated with MYBA/MYB1 such as ethylene-associated genes,etc.Additionally,VcbZIP55s and VcCOP1s were activated and inactivated by the bagging treatment,respectively.These findings provided a framework of light-independent anthocyanin biosynthesis in blueberry fruit. 展开更多
关键词 Vaccinium corymbosum Bagging Light-independent regulation Transcriptome Metabolome Anthocyanins MYBA Ethylene signaling
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In situ construction of ammonium phosphomolybdate@ZIF-8 composite for Rb+and Cs+adsorption performance 认领 引用
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作者 WANG Yang ZHANG Lulu +4 位作者 HE Hanjiang ZHANG Xia SUN Xiaohong WANG Fan WANG Shuli 《无机化学学报》 SCIE CAS CSCD 北大核心 2026年第4期826-842,共17页
A metal-organic framework/inorganic composite(ZIF-8@AMP)was synthesized by the in situ introduction of the active component ammonium phosphomolybdate(AMP)during the ambient solution-phase synthesis of the metal-organi... A metal-organic framework/inorganic composite(ZIF-8@AMP)was synthesized by the in situ introduction of the active component ammonium phosphomolybdate(AMP)during the ambient solution-phase synthesis of the metal-organic framework(ZIF-8).The structure and properties of the composite were characterized using scanning electron microscopy(SEM),X-ray powder diffraction(XRD),X-ray photoelectron spectroscopy(XPS),thermogravimetric analysis(TGA),and Fourier transform infrared spectroscopy(FTIR).Its adsorption performance for Rb+and Cs+in water was investigated.Results indicate that ZIF-8@AMP exhibited adsorption efficiencies of 93.5%and 95.6%for Rb+and Cs+within 30 min,with maximum adsorption capacities of 92.7 and 104.5 mg·g-1,respectively.After five adsorption-desorption cycles,it maintained high adsorption capacity and achieved over 84.9%adsorption efficiency for Rb+and Cs+in actual brine samples.The adsorption of ZIF-8@AMP for Rb+and Cs+follows pseudosecond-order kinetics and the Langmuir adsorption isotherm,indicating an endothermic,entropy-increasing,and spontaneous process.The adsorption mechanism involves electrostatic attraction and ion exchange between ZIF-8@AMP and Rb+and Cs+. 展开更多
关键词 ammonium phosphomolybdate ZIF-8 rubidium cesium adsorption
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Progress in Surface-Enhanced Raman Scattering-Based Volatile Organic Compounds Detection:Materials,Application,and Prospects 认领 引用
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作者 Yuening Wang Lin Qiu +9 位作者 Jian Yu Wen Ma Xiaoyu Song Mingjian Zhang Yujiao Xie Aochi Liu Li Sun Xiangyu Meng Jie Lin Xiaotian Wang 《Rare Metals》 SCIE EI CAS CSCD 2026年第3期14-35,共22页
The detection of volatile organic compounds(VOCs)holds significant implications in environmental monitoring and disease diagnosis.Traditional gas detection technologies are constrained by complex operation and high co... The detection of volatile organic compounds(VOCs)holds significant implications in environmental monitoring and disease diagnosis.Traditional gas detection technologies are constrained by complex operation and high cost,thereby failing to satisfy real-time detection demands.Surface-enhanced Raman scattering(SERS)provides a noble approach for trace VOCs detection,as it possesses single-molecule sensitivity,rapid response,and the ability to analyze chemical structures without being affected by water molecules.Researchers have successfully achieved precise identification of trace VOCs through the meticulous design of SERS substrates,demonstrating excellent application potential in practical detection.This review comprehensively summarizes the research progress and application of SERS technology in VOCs detection,covering the structural design of SERS substrates and the transformation of actual gas detection methods.Specifically,three core substrate structures include noble metal nanostructures,porous semiconductor composite nanostructures,and noble metal-semiconductor composite porous nanostructures that combine the advantages of both were delved into deeply.Furthermore,it also provides a detailed account of the technological innovations in VOCs detection based on SERS technology,expanding the application scope of SERS technology.Nevertheless,the SERS technology still faces significant challenges in VOC gas detection,including nonspecific adsorption in complex matrices,insufficient long-term substrate stability,the need to simultaneously identify multiple components in a mixed gas,etc.This review summarizes the current challenges in detail and looks forward to future research directions and development prospects. 展开更多
关键词 noble metal noble metal-semiconductor semiconductor SERS VOCs
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Single-Atom-Dispersed FeNC/FeS2 Nanocluster for High-Performance Sodium Metal Battery With Hybrid Electrochemical Behavior 认领 引用
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作者 Yuan Liu Geng Li +9 位作者 Shunxian Yu Xinran Qi Zhuang‐Chun Jian Wei Zhan Baoxiu Hou Shuming Zeng Hui Shao Jianjun Song Yao Xiao Xiaoxian Zhao 《Carbon Energy》 SCIE EI CAS CSCD 2026年第3期117-128,共12页
The rate capability and cycling stability of sodium metal batteries taking FeS2 or sulfur as cathode are limited due to their low reaction kinetics and severe shuttle effect.Herein,we rationally design a novel sing... The rate capability and cycling stability of sodium metal batteries taking FeS2 or sulfur as cathode are limited due to their low reaction kinetics and severe shuttle effect.Herein,we rationally design a novel single-atom-dispersed S2-FeNC/FeS2 nanocluster heterojunction embedded in carbon spheres(SFNC/FeS2) for the electrode material of sodium metal batteries.Interestingly,during the discharging process,the Na+ is inserted into FeS2 to generate Na2S,as well as the unique electrochemical reaction between S2-FeNC and Na+ to form Na2S.Meanwhile,the FeNC can adsorb Na2S and catalyze the conversion from Na2S and Fe to FeS2 or from Na2S and FeNC to S2-FeNC for suppressing the shuttle effect and promoting the distinct hybrid reversible electrochemical behavior,which improves performance tremendously.Notably,the SFNC/FeS2 electrode delivers a specific capacity of 338.7 mAh g-1 after superlong 2000 cycles at a current density of 5.0 A g-1 and achieves a high energy density of 430.1 Wh Kg-1 at a current density of 0.05 A g-1.This work presents a novel approach to studying sodium metal batteries with hybrid behavior for excellent high energy density and cycling stability. 展开更多
关键词 electrochemical behavior Fe single atom FeS2 sodium metal battery sodium sulfur battery
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Soil science research in Research Center for Eco-Environmental Sciences:Review and outlook 认领 引用
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作者 Baodong Chen Zhipeng Hao +13 位作者 Lei Luo Nan Wu Wenju Liu Dong Zhu Yuan Ge Weiping Chen Wentao Jiao Xin Zhang Siyi Liu Jupei Shen Ke-Qing Xiao Wei Fu Songlin Wu Yong-Guan Zhu 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第3期64-74,共11页
Soil science research involves the composition,properties,processes,and functions of soil under natural conditions and anthropogenic utilization,and provides scientific basis for the utilization,protection,and sustain... Soil science research involves the composition,properties,processes,and functions of soil under natural conditions and anthropogenic utilization,and provides scientific basis for the utilization,protection,and sustainable management of soil resources.This review summarizes the significant contributions of Research Center for EcoEnvironmental Sciences(RCEES),Chinese Academy of Sciences,to the advances of soil science.Over past decades,RCEES has conducted innovative research in areas such as soil pollution and remediation,biogeochemical cycling of macro and trace elements and soil microbial ecology.Groundbreaking discoveries have been achieved in research directions such as metal transformation and translocation in the soil-plant continuum,soil microbial diversity and biogeography,and the environmental and health risk of soil contamination.In recent years,on-going projects also involves cutting-edge hotspots,including the environmental behavior of emerging pollutants,and soil organic matter dynamics.The soil lab in RCEES has undertaken important research projects and trained a group of dynamic young scientists,and has also been instrumental in establishing international collaborations,enhancing its global impact through participation in global soil research initiatives and conferences.Concurrently,soil science at RCEES is moving forward to the resilience of soil ecosystems to global changes,integrating soil health into the One Health framework,and sustainable soil management practices.RCEES remains a key player in shaping the future of soil science,contributing to both scientific advances and the sustainable management of soil resources in China. 展开更多
关键词 Soil environmental science Plant-soil interactions Soil microbial ecology Biogeochemical cycling Emerging pollutants
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Genome-wide association study of HBV-related hepatocellular carcinoma identifies a functional variant at the FAM114A1 locus 认领 引用
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作者 Hong-Ping Yu Bang-De Xiang +29 位作者 Ji Qian Hongliang Liu Yuan-Feng Li Qiuling Lin Shun Liu Junjie Wei Shicheng Zhan Binbin Jiang Juncheng Dai Liang Ma Litu Zhang Yingchun Liu Qiuping Wen Wenfeng Gong Shengping Li Yanji Jiang Ji Zheng Tianyi Zhu Zihan Zhou Xiaoyun Zeng Ziliang Wang Ji-Ao Wang Rui Guo Yuan Yang Qingyi Wei Gangqiao Zhou Xiao-Qiang Qiu Weizhong Tang Mengyun Wang Ruoxin Zhang 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2026年第4期643-654,共12页
Liver cancer ranks sixth in cancer incidence and third in cancer-related deaths worldwide.Hepatocellular carcinoma(HCC)is the primary histological subtype,and hepatitis B virus(HBV)carriers have a higher risk of HCC.A... Liver cancer ranks sixth in cancer incidence and third in cancer-related deaths worldwide.Hepatocellular carcinoma(HCC)is the primary histological subtype,and hepatitis B virus(HBV)carriers have a higher risk of HCC.Although several susceptibility loci for HCC have been identified in East Asian populations through genome-wide association studies(GWAS),the underlying biological mechanisms of this malignancy remain incompletely understood.Here,we conduct a two-stage GWAS including 2413 cases and 2794 HBV-positive controls from a high-incidence region in Southern China.The function of the susceptibility locus is investigated by bioinformatic and experimental approaches,supported by a xenograft model.We identify a 4p14 locus significantly associated with the risk of HCC(rs55718051,OR[95%CI]=0.73[0.67-0.80],Pmeta=9.14×10-11),and 18q23 locus with borderline significance(rs12964643:OR[95%CI]=0.75[0.67-0.83],Pmeta=1.11×10-7).Functional experiments indicate the role of rs55718051 in FAM114A1 expression regulation,possibly through the interaction with FOXA1.Knockdown of FAM114A1 significantly promote the oncogenic phenotypes in liver cancer cells,suggesting its potential tumor suppressor role.Our findings expand the understanding of HCC susceptibility and suggest FAM114A1 as a potential suppressor in HBV-related HCC carcinogenesis. 展开更多
关键词 Hepatocellular carcinoma Hepatitis B virus Genome-wide association study Functional variant Cancer susceptibility
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Establishment of a novel field in vivo Agrobacterium tumefaciens mediated transgenic system in fruit tree Chinese jujube 认领 引用
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作者 Tingting Ye Xiaoxue Guo +7 位作者 Yuting Duan Meiyi Zhao Xinyu Zhang Di Xun Jiurui Wang Lixin Wang Mengjun Liu Ping Liu 《Horticultural Plant Journal》 SCIE CAS CSCD 2026年第4期955-959,共5页
Agrobacterium tumefaciens mediated transgenic system is an effective and convenient method for plant breeding.However,the method was almost conducted in uitro,which requires strict tissue culture conditions and it was... Agrobacterium tumefaciens mediated transgenic system is an effective and convenient method for plant breeding.However,the method was almost conducted in uitro,which requires strict tissue culture conditions and it was time consuming from tissue culture plantlets to field evaluation.Therefore,it is crucial to develop a tissue-culture-free field in uiuo transgenic technique.In the current study,we established a novel field in uiuo A.tumefaciens mediated genetic transformation system for Chinese jujube with a pink colormarker gene SUPER RUBY. 展开更多
关键词 tissue culture genetic transformation system chinese jujube agrobacterium tumefaciens mediated transgenic system vivo plant breedinghoweverthe tissue culture plantlets novel field
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Phosphorus source-sink distributions and fluxes in shallow-water wetland sediments:Insights from multiple habitats,varying water quality,and microbial communities 认领 引用
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作者 Yuwei Zhang Shengqi Zhang +3 位作者 Yangyang Han Cheng Guo Ling Liu Hongjie Wang 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第6期752-767,共16页
Fluctuation in overlying water quality across multiple habitats and the reservoir conditions of different sediment pollutants significantly influence the“source-sink”effect of endogenous nutrients in shallow-water w... Fluctuation in overlying water quality across multiple habitats and the reservoir conditions of different sediment pollutants significantly influence the“source-sink”effect of endogenous nutrients in shallow-water wetlands.This study investigated the sediment nutrient composition in four habitats(i.e.open-water area,ditch,pond,and reed marsh)within Baiyangdian wetland(BYDW),combined with the simulated release experiment to estimate the nutrient exchange flux under the different overlying water qualities.The findings indicate that the nutrient contents of ditch sediments were significantly higher than those in the other habitats.The ditch overlying water exhibited significantly higher concentrations of soluble reactive phosphorus(SRP),total phosphorus(TP),and ammonia nitrogen(NH4+-N),and the maximum contents were 0.009 mg/L,0.0443 mg/L,and 0.4057 mg/L,respectively.Sediment horizon depth significantly influenced the composition of different P fractions.While residual phosphorus(Res-P)and calcium-bound phosphorus(Ca-P)comprised a substantial portion of TP,about 60.53%-79.46%.Sediments in ditch,pond,and reed marsh areas acted as TP sources under the raw water quality condition,and the releasing rate was 4.68,1.80,and 0.18 mg/(m2・day).The overlying water quality,sediment pH,organic matter(OM)content,as well as phosphorus speciation significantly influenced the exchange of phosphorus-containing substances.Both Chloroflexi and Proteobacteria significantly contributed to the degradation of sediment nutrients in open-water and reed areas.Ditch exhibited the highest TP release,with the release amount W(TP)varied from 64.15–72.17 t/yr.The ditch and pond areas exhibited relatively strong“source”potential,highlighting the need for effective management of endogenous pollution. 展开更多
关键词 Multiple habitats Nutrients distribution Source-sink Environmental factors
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Visible-Light-Induced Phosphorylation Cyclization to Phosphorylated Indole-Fused Diazepines 认领 引用
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作者 Hou Xinyi Shi Tongtong +3 位作者 Li Zejiang Dong Qinghao Sun Kai Wang Xin 《有机化学》 SCIE CAS CSCD 北大核心 2026年第4期1776-1787,共12页
novel visible-light induced phosphorylation cyclization to indole-fused medium-sized diazepines was established under room temperature.Broad substrate scope,good functional group compatibility,large-scale synthesis an... novel visible-light induced phosphorylation cyclization to indole-fused medium-sized diazepines was established under room temperature.Broad substrate scope,good functional group compatibility,large-scale synthesis and derivatization via nitration,chlorination and cyanation demonstrate the utility of this protocol.P-centered radical involed energy transfer(EnT)process was proposed based on radical inhibition experiments,visible-light irradiation on-off test,apparent quantum efficiency(AQE)calculation,UV-vis absorption spectroscopic studies and cyclic voltammetry experiments. 展开更多
关键词 photocatalysis radical cyclization phosphorylation medium-sized N-heterocycles
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Sustainable alternative to biochar:Effects of oxychar on soil carbon sequestration pathway and microbial communities 认领 引用
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作者 Cheng Ji Chenchen Zhao +8 位作者 Shutao Wang Qinggang Meng Huiwei Zhao Yifan Li Duo Li Mingzhen Xing Shiming Su Bing Han Wei Liu 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2026年第5期823-833,共11页
The rapid development of agriculture poses significant challenges to carbon sequestration and sustainable agriculture due to frequent plowing cultivation,has resulted in a notable decline in soil quality.The applicati... The rapid development of agriculture poses significant challenges to carbon sequestration and sustainable agriculture due to frequent plowing cultivation,has resulted in a notable decline in soil quality.The application of carbon materials is regarded as a synergistic and effective approach for conserving organic carbon,increasing microbial activity,and promoting plant growth.To explore whether oxychar can serve as a substitute for traditional biochar(HBC)in enhancing soil carbon sequestration,a method combining a 680-day field experiment with a pot experiment was adopted to assess the impacts of oxychar on soil carbon sequestration,microbial communities,and rape growth.The study revealed that the addition of oxychar reduces soil pH,increases soil electrical conductivity and CO2emissions,and achieves carbon sequestration by increasing the content of readily oxidizable organic carbon in the soil.The soil carbon pool management index of the oxychar treatment(131.32)was significantly higher than that of the traditional biochar treatment(101.93),indicating that oxychar has higher ability to improve soil organic carbon quality.Both the oxychar and HBC treatments improved the richness and diversity of the soil bacterial community.However,oxychar indirectly influenced the soil microbial community by increasing soil electrical conductivity and promoted soil carbon sequestration through carbohydrate metabolism.And,oxychar could promote plant growth in many ways.In general,this study provides a theoretical basis for the practical application of oxychar replacing HBC in soil carbon sequestration. 展开更多
关键词 Oxychar Biochar Soil carbon sequestration Microbial community
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Escape behavior and refuge selection preferences by two common urban birds 认领 引用
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作者 Haijie Zhang Yining Li +3 位作者 Yiran Wang Guofen Zhu Jiaojiao Wang Laikun Ma 《Avian Research》 SCIE CAS CSCD 2026年第1期84-94,共11页
Urbanization destroys wildlife habitats,fragmenting them into small patches with poor connectivity,leading to population declines in species sensitive to such chan ges.Escape is the most common anti-predator strategy ... Urbanization destroys wildlife habitats,fragmenting them into small patches with poor connectivity,leading to population declines in species sensitive to such chan ges.Escape is the most common anti-predator strategy adopted by birds,refuges in habitats reduce or eliminate predation risk.Therefore,creating habitats with suitable refuges for birds has significant implications for their conservation.However,there have been few studies on refuge selection in birds.This study examined the Eurasian Tree Sparrow(Passer montanus)and Oriental Magpie(Pica serica)in urban and rural areas of Chengde City,northern China by measuring their alert distance(AD),flight initiation distance(FID),an d distance fled(DF)and analyzed their refuge selection characteristics after escaping.The FID/AD ratio was employed to assess the behavioral differences of birds in the risk trade-off.The results showed that the FID and FID/AD of both species were lower in urban areas than in rural areas and were negatively correlated with immediate human density.Sparrow FID was significantly affected by group size and landing substrate type.The FID of sparrows was positively correlated with the group size.The sparrows that fled to bushes escaped earlier.In urban and rural areas,sparrows exhibited significantly lower FID,DF,and FID/AD than magpies.The species adopted different refuge selection strategies,with magpies preferentially selecting trees with greater vertical height and sparrows selecting both trees and bushes.Further analysis indicated that the horizontal and vertical distances fled of both species were lower when fleeing to bushes.Urban planning and conservation areas construction should incorporate the ecological needs of local bird species to rationally configure their habitat structure,thereby optimizing the effect of avian conservation. 展开更多
关键词 Anti-predator behavior Avian tolerance Flight initiation distance Refuge Urbanization
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Electrophilic aryl spiroannulation induced by diaryliodonium salts:efficient synthesis of[5,5]-spiro lactone-lactam scaffolds fromα-cyanocarboxylates 认领 引用
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作者 Zhiyuan Bao Yifei Li +2 位作者 Ruitong Zhang Zhengsen Yu Chao Chen 《Green Synthesis and Catalysis》 CSCD 2026年第3期294-302,共9页
Spirocyclic architectures represent one of the privileged three-dimensional scaffolds in pharmaceutical chemistry and drug discovery,while the new-skeletal synthesis of spiromolecules from simple starting materials re... Spirocyclic architectures represent one of the privileged three-dimensional scaffolds in pharmaceutical chemistry and drug discovery,while the new-skeletal synthesis of spiromolecules from simple starting materials remains a challenging task.Here,we report the first diaryliodonium salt-mediated electrophilic aryl spiroannulation reaction starting from simple substratesα-cyanocarboxylates.With this strategy,a broad spectrum of new[5,5]spiro-fused skeletons can be efficiently constructed in one step via Cu-catalyzed cascade N-arylation-acylation and etheral skeleton rearrangement reaction.The key point of this transformation is the intramolecular electrophilic cyclization due to the nucleophilicity of O-atom and electrophilicity ofα-C induced by diaryliodonium salts.With this protocol,the more challenging activation of ether bonds was achieved via diaryliodonium salts-mediated.This method has the major advantages of a broad substrate scope and excellent functional group compatibility.Further synthetic elaboration was performed using substrate with steric hindrance to showcase the versatility of this methodology. 展开更多
关键词 Electrophilic arylation Spiroannulation Diaryliodonium salts Lactones Lactams Cyanocarboxylates Rearrangement
INHBA Promotes the Progression of Gastric Cancer by Activating MAPK Signaling Pathway via Targeting ITGA6 认领 引用
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作者 Guojian Zhou Rui Zhang +7 位作者 Lei Nie Yi Si Ting Liu Jing Wang Shuangshuang Han Mingda Xuan Jia Wang Weifang Yu 《Oncology Research》 SCIE 2026年第3期644-666,共23页
Objectives:Gastric cancer(GC)is among the most prevalent malignancies worldwide,ranking as the fifth most common cancer and the fifth leading cause of cancer-related mortality.This study intends to investigate how Inh... Objectives:Gastric cancer(GC)is among the most prevalent malignancies worldwide,ranking as the fifth most common cancer and the fifth leading cause of cancer-related mortality.This study intends to investigate how Inhibin subunit beta A(INHBA)promotes the progression of GC by activating the mitogen-activated protein kinase(MAPK)signaling pathway via targeting Integrin alpha-6(ITGA6).Methods:Quantitative reverse transcription-Polymerase Chain Reaction(qRT-PCR)and Immunohistochemistry(IHC)were utilised to validate the expression levels of INHBA in GC,which were subsequently correlated with the clinicopathological factors and outcomes.Cellular and animal studies were conducted to ascertain the role of INHBA in GC.RNA-sequencing(RNA-seq)and bioinformatics analysis were used to screen for the downstream target and pathway of INHBA,with Co-immunoprecipitation(Co-IP),Co-Immunofluorescent(Co-IF),Western blot(WB)and Rescue experiments validating their mechanisms of action in GC.Results:IHC and qRT-PCR analysis confirmed that GC tissues exhibited higher INHBA expression than adjacent noncancerous tissues.This elevated INHBA expression was found to be significantly associated with the incidence of tumor lesions,lymph node metastasis,and progression to higher TNM stages.Functional experiments showed that INHBA promoted GC cell proliferation and enhanced their migration and invasion in vitro while inhibiting apoptosis.Animal studies results indicated that INHBA overexpression promoted tumor growth and increased tumor weight and volume.Through a series of experiments,including RNA-seq,Co-IP,Co-IF,WB,and rescue assays,this study demonstrated that INHBA promotes GC progression by targeting ITGA6 to regulate the MAPK signaling pathway.Conclusions:INHBA/ITGA6/MAPK axis can provide new insights into GC therapy.Targeted INHBA inhibition holds promise as a therapeutic approach for GC treatment. 展开更多
关键词 Gastric cancer(GC) inhibin subunit beta A(INHBA) integrin alpha-6(ITGA6) RNA-sequencing(RNA-seq) mitogen-activated protein kinase(MAPK)
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